| Entry |
|
|---|
| Name |
Insulin human (USP/INN);
Insulin human (genetical recombination) (JP17);
Insulin human (biosynthesis) (JAN);
Insulin human (synthesis) (JAN);
Humulin (TN) |
|---|
| Product |
|
|---|
| Formula |
C257H383N65O77S6
|
|---|
| Exact mass |
5803.6376
|
|---|
| Mol weight |
5807.5702
|
|---|
| Sequence |
(A chain) Gly Ile Val Glu Gln Cys Cys Thr Ser Ile Cys Ser Leu Tyr
Gln Leu Glu Asn Tyr Cys Asn
(B chain) Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala
Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro Lys Thr
(Disulfide bridge: A6-A11, A7-B7, A20-B19) |
|---|
| Type |
Peptide |
|---|
| Class |
Antidiabetic agent
DG01636 Insulin and analog
DG01802 Human insulin
DG01798 Human insulin, fast-acting
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
|
|---|
| Remark |
| Therapeutic category: | 2492 |
|
|---|
| Efficacy |
Antidiabetic, Insulin receptor agonist |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
CYP induction: CYP1A2 [HSA: 1544]
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10A INSULINS AND ANALOGUES
A10AB Insulins and analogues for injection, fast-acting
A10AB01 Insulin (human)
D03230 Insulin human (USP/INN) <JP/US>
A10AC Insulins and analogues for injection, intermediate-acting
A10AC01 Insulin (human)
D03230 Insulin human (USP/INN) <JP/US>
A10AD Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting
A10AD01 Insulin (human)
D03230 Insulin human (USP/INN) <JP/US>
A10AE Insulins and analogues for injection, long-acting
A10AE01 Insulin (human)
D03230 Insulin human (USP/INN) <JP/US>
A10AF Insulins and analogues for inhalation
A10AF01 Insulin (human)
D03230 Insulin human (USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
249 Miscellaneous
2492 Pancreatic hormones
D03230 Insulin human (USP/INN); Insulin human (genetical recombination) (JP17); Insulin human (biosynthesis) (JAN); Insulin human (synthesis) (JAN)
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
INSR family
INSR (CD220)
D03230 Insulin human (USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D03230 Insulin human (genetical recombination)
D03230 Insulin human (genetical recombination) injection
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D03230
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03230
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| Other DBs |
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| LinkDB |
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