KEGG   DRUG: Butenafine
Entry
D07596                      Drug                                   

Name
Butenafine (INN)
Formula
C23H27N
Exact mass
317.2144
Mol weight
317.4672
Structure
Simcomp
Remark
Same as: C08067
ATC code: D01AE23
Chemical structure group: DG00378
Product (DG00378): D01093<JP/US>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Benzylamine derivative
Target
squalene epoxidase [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis
Structure map
map07026  Antifungal agents
map07114  Naphthalene family
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE23 Butenafine
      D07596  Butenafine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Butenafine
    D07596  Butenafine (INN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Butenafine
    D07596  Butenafine (INN)
Other DBs
CAS: 101828-21-1
PubChem: 51091907
ChEBI: 3238
ChEMBL: CHEMBL990
DrugBank: DB01091
LigandBox: D07596
NIKKAJI: J276.436I
LinkDB
KCF data

ATOM        24
            1   C8x C    14.0000  -18.9000
            2   C8x C    14.0000  -20.3000
            3   C8x C    15.2124  -21.0000
            4   C8y C    16.4249  -20.3000
            5   C8y C    16.4249  -18.9000
            6   C8x C    15.2124  -18.2000
            7   C8x C    17.6373  -21.0000
            8   C8x C    18.8497  -20.3000
            9   C8x C    18.8497  -18.9000
            10  C8y C    17.6373  -18.2000
            11  C1b C    17.6373  -16.8000
            12  N1c N    18.8518  -16.0988
            13  C1b C    20.0483  -16.7898
            14  C8y C    21.2351  -16.1046
            15  C8x C    22.4266  -16.7928
            16  C8x C    23.6391  -16.0929
            17  C8y C    23.6393  -14.6929
            18  C8x C    22.4478  -14.0048
            19  C8x C    21.2353  -14.7046
            20  C1d C    24.8641  -13.9858
            21  C1a C    26.0766  -13.2858
            22  C1a C    25.5667  -15.2026
            23  C1a C    24.1668  -12.7780
            24  C1a C    18.8518  -14.7002
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   14  19 1
            22   17  20 1
            23   20  21 1
            24   20  22 1
            25   20  23 1
            26   12  24 1

» Japanese version   » Back

KEGG   DRUG: Butenafine hydrochloride
Entry
D01093                      Drug                                   

Name
Butenafine hydrochloride (JP17/USAN);
Mentax (TN);
Volley (TN)
Product
Formula
C23H27N. HCl
Exact mass
353.191
Mol weight
353.9281
Structure
Simcomp
Remark
Same as: C12490
Therapeutic category: 2659
ATC code: D01AE23
Chemical structure group: DG00378
Product (DG00378): D01093<JP/US>
Efficacy
Antifungal, Ergosterol biosynthesis inhibitor
  Disease
Tinea (pityriasis) versicolor [DS:H01334]
Comment
Benzylamine derivative
Target
squalene epoxidase [KO:K00511]
  Pathway
ko00100  Steroid biosynthesis
Structure map
map07026  Antifungal agents
map07114  Naphthalene family
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AE Other antifungals for topical use
     D01AE23 Butenafine
      D01093  Butenafine hydrochloride (JP17/USAN) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Topical Anti-infectives
   Antifungals, dermatological
    Butenafine
     D01093  Butenafine hydrochloride (JP17/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   265  Antiparasitic dermatosis agents
    2659  Others
     D01093  Butenafine hydrochloride (JP17/USAN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  58 Ringworm drugs
   D01093  Butenafine hydrochloride (JP17/USAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Butenafine
    D01093  Butenafine hydrochloride (JP17/USAN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Butenafine
    D01093  Butenafine hydrochloride (JP17/USAN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01093  Butenafine hydrochloride
  D01093  Butenafine hydrochloride solution
  D01093  Butenafine hydrochloride spray
  D01093  Butenafine hydrochloride cream
Rx-to-OTC switch list in the USA [br08315.html]
 D01093
Rx-to-OTC switch list in Japan [br08314.html]
 D01093
Other DBs
CAS: 101827-46-7
PubChem: 7848156
ChEBI: 31325
ChEMBL: CHEMBL1200397
DrugBank: DB01091
LigandBox: D01093
NIKKAJI: J277.857B
LinkDB
KCF data

ATOM        25
            1   C8x C    18.4139  -17.1211
            2   C8x C    18.4139  -18.5242
            3   C8x C    19.6290  -19.2258
            4   C8y C    20.8442  -18.5242
            5   C8y C    20.8442  -17.1211
            6   C8x C    19.6290  -16.4196
            7   C8x C    22.0593  -19.2258
            8   C8x C    23.2745  -18.5242
            9   C8x C    23.2745  -17.1211
            10  C8y C    22.0593  -16.4196
            11  C1b C    22.0593  -15.0164
            12  N1c N    23.2766  -14.3137
            13  C1b C    24.4758  -15.0062
            14  C1a C    23.2766  -12.9119
            15  C8y C    25.6653  -14.3195
            16  C8x C    26.8594  -15.0092
            17  C8x C    28.0746  -14.3077
            18  C8y C    28.0748  -12.9046
            19  C8x C    26.8807  -12.2150
            20  C8x C    25.6655  -12.9163
            21  C1d C    29.3024  -12.1959
            22  C1a C    30.5176  -11.4944
            23  C1a C    30.0065  -13.4155
            24  C1a C    28.6035  -10.9854
            25  X   Cl   30.3101  -17.1500
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   12  14 1
            16   13  15 1
            17   15  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   15  20 1
            23   18  21 1
            24   21  22 1
            25   21  23 1
            26   21  24 1

» Japanese version   » Back

DBGET integrated database retrieval system