KEGG   DRUG: Levorphanol
Entry
D08123                      Drug                                   

Name
Levorphanol (INN)
Formula
C17H23NO
Exact mass
257.178
Mol weight
257.3706
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C08014
Chemical structure group: DG01341
Product (DG01341): D00841<US>
Efficacy
Analgesic (narcotic)
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08123  Levorphanol (INN)
Other DBs
CAS: 77-07-6
PubChem: 96024813
ChEBI: 6444
ChEMBL: CHEMBL1617689 CHEMBL592
DrugBank: DB00854
LigandBox: D08123
NIKKAJI: J86.103K
LinkDB
KCF data

ATOM        19
            1   C1z C    22.8900  -18.6200
            2   C1y C    24.0800  -19.3200
            3   C8y C    22.8900  -17.2900
            4   C1x C    24.0800  -17.9900
            5   C1x C    21.7700  -19.3200
            6   C1y C    25.2700  -18.6200
            7   C1x C    24.0800  -20.6500
            8   C8y C    24.0800  -16.5900
            9   C8x C    21.7000  -16.5900
            10  C1x C    26.4600  -17.9200
            11  C1x C    21.7700  -20.6500
            12  C1x C    25.2700  -17.2900
            13  N1y N    26.4600  -19.3200
            14  C1x C    22.9600  -21.3500
            15  C8x C    24.0800  -15.2600
            16  C8y C    21.7000  -15.2600
            17  C1a C    27.7900  -19.3200
            18  C8x C    22.8900  -14.5600
            19  O1a O    20.5800  -14.5600
BOND        22
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     1   5 1
            5     2   6 1
            6     2   7 1
            7     3   8 2
            8     3   9 1
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    6  13 1 #Up
            13    7  14 1
            14    8  15 1
            15    9  16 2
            16   13  17 1
            17   15  18 2
            18   16  19 1
            19    8  12 1
            20   10  13 1
            21   11  14 1
            22   16  18 1

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KEGG   DRUG: Levorphanol tartrate
Entry
D00841                      Drug                                   

Name
Levorphanol tartrate (USP);
Levorphanol tartrate dihydrate;
Levo-dromoran (TN)
Product
  Generic
Formula
C17H23NO. C4H6O6. 2H2O
Exact mass
443.2155
Mol weight
443.488
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Chemical structure group: DG01341
Product (DG01341): D00841<US>
Efficacy
Analgesic (narcotic)
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Levorphanol
    D00841  Levorphanol tartrate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00841  Levorphanol tartrate (USP) <US>
Other DBs
CAS: 5985-38-6
PubChem: 7847906
ChEBI: 6445
DrugBank: DB00854
LigandBox: D00841
LinkDB
KCF data

ATOM        31
            1   C1z C    19.0596  -19.7705
            2   C1y C    20.2344  -20.4367
            3   C8y C    19.0538  -18.4029
            4   C1x C    20.2285  -19.0751
            5   C1x C    17.8966  -20.4543
            6   C1y C    21.4091  -19.7588
            7   C1x C    20.2402  -21.7868
            8   C8y C    20.2285  -17.7250
            9   C8x C    17.8734  -17.7250
            10  C1x C    22.6421  -19.1392
            11  C1x C    17.9025  -21.7985
            12  C1x C    21.4091  -18.3972
            13  N1y N    22.5779  -20.4309
            14  C1x C    19.0772  -22.4647
            15  C8x C    20.2285  -16.3691
            16  C8y C    17.8734  -16.3691
            17  C1a C    23.9337  -20.4309
            18  C8x C    19.0538  -15.6912
            19  O1a O    16.6870  -15.6912
            20  C1c C    30.0658  -17.7504
            21  C1c C    28.8502  -18.4517
            22  C6a C    31.2815  -18.4517
            23  O1a O    30.0600  -16.3420
            24  C6a C    27.6405  -17.7504
            25  O1a O    28.8443  -19.8543
            26  O6a O    32.4912  -17.7504
            27  O6a O    31.2698  -19.8543
            28  O6a O    26.4249  -18.4517
            29  O6a O    27.6345  -16.3420
            30  O0  O    37.4500  -18.6900
            31  O0  O    37.4500  -18.6900
BOND        31
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Up
            4     1   5 1
            5     2   6 1
            6     2   7 1
            7     3   8 2
            8     3   9 1
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12    6  13 1 #Up
            13    7  14 1
            14    8  15 1
            15    9  16 2
            16   13  17 1
            17   15  18 2
            18   16  19 1
            19    8  12 1
            20   10  13 1
            21   11  14 1
            22   16  18 1
            23   20  21 1
            24   20  22 1
            25   20  23 1 #Up
            26   21  24 1
            27   21  25 1 #Up
            28   22  26 1
            29   22  27 2
            30   24  28 1
            31   24  29 2
BRACKET     1    35.3500  -19.7400   35.3500  -17.7100
            1    38.2900  -17.7100   38.2900  -19.7400
            1  2
 ORIGINAL  1   31
 REPEAT    1   32

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