| Entry |
|
|---|
| Name |
Metaraminol (INN) |
|---|
| Formula |
C9H13NO2
|
|---|
| Exact mass |
167.0946
|
|---|
| Mol weight |
167.205
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypotensive, alpha-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA09 Metaraminol
D08192 Metaraminol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00218 Metaraminol
D08192 Metaraminol
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG00218 Metaraminol
D08192 Metaraminol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D08192 Metaraminol (INN)
ADRA2
D08192 Metaraminol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00218 Metaraminol
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG00218 Metaraminol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C8y C 8.1200 -18.6900
2 C8x C 8.1200 -20.0900
3 C8x C 9.3324 -20.7900
4 C8x C 10.5449 -20.0900
5 C8y C 10.5449 -18.6900
6 C8x C 9.3324 -17.9900
7 O1a O 6.9076 -17.9900
8 C1c C 11.7760 -17.9790
9 C1c C 12.9812 -18.6747
10 O1a O 11.7757 -16.5901
11 N1a N 14.1635 -17.9919
12 C1a C 12.9816 -20.0896
BOND 12
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 5 8 1
9 8 9 1
10 8 10 1 #Up
11 9 11 1 #Up
12 9 12 1
|
|---|
