KEGG   DRUG: Oxymorphone
Entry
D08323                      Drug                                   

Name
Oxymorphone (INN)
Formula
C17H19NO4
Exact mass
301.1314
Mol weight
301.3371
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C08019
Chemical structure group: DG01343
Product (DG01343): D00844<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D08323  Oxymorphone (INN)
Other DBs
CAS: 76-41-5
PubChem: 96025010
ChEBI: 7865
ChEMBL: CHEMBL963
DrugBank: DB01192
LigandBox: D08323
NIKKAJI: J4.174B
LinkDB
KCF data

ATOM        22
            1   C1z C    22.8900  -18.6200
            2   C8y C    22.8900  -17.2200
            3   C1z C    24.0800  -19.2500
            4   C1y C    21.7700  -19.2500
            5   C8y C    21.7000  -16.5900
            6   C8y C    24.0800  -16.5900
            7   C1y C    25.2000  -18.5500
            8   C1x C    24.0800  -20.5800
            9   O1a O    25.2000  -20.2300
            10  O2x O    21.0700  -17.9200
            11  C5x C    21.7700  -20.5800
            12  C8y C    21.7000  -15.2600
            13  C1x C    25.2000  -17.2200
            14  C8x C    24.0800  -15.2600
            15  N1y N    26.3900  -19.2500
            16  C1x C    22.8900  -21.2800
            17  O5x O    20.5800  -21.2800
            18  C8x C    22.8900  -14.5600
            19  O1a O    20.5800  -14.5600
            20  C1a C    27.7200  -19.2500
            21  C1x C    26.3900  -17.9200
            22  C1x C    24.0800  -17.9200
BOND        26
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     3   8 1
            8     3   9 1 #Up
            9     4  10 1 #Down
            10    4  11 1
            11    5  12 2
            12    6  13 1
            13    6  14 1
            14    7  15 1 #Up
            15    8  16 1
            16   11  17 2
            17   12  18 1
            18   12  19 1
            19   15  20 1
            20    5  10 1
            21    7  13 1
            22   11  16 1
            23   14  18 2
            24    1  22 1 #Up
            25   22  21 1
            26   15  21 1 #Up

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KEGG   DRUG: Oxymorphone hydrochloride
Entry
D00844                      Drug                                   

Name
Oxymorphone hydrochloride (USP);
Numorphan (TN);
Opana (TN)
Product
  Generic
Formula
C17H19NO4. HCl
Exact mass
337.1081
Mol weight
337.798
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Chemical structure group: DG01343
Product (DG01343): D00844<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
USP drug classification [BR:br08302]
 Analgesics
  Opioid Analgesics, Long-acting
   Oxymorphone
    D00844  Oxymorphone hydrochloride (USP)
  Opioid Analgesics, Short-acting
   Oxymorphone
    D00844  Oxymorphone hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00844  Oxymorphone hydrochloride (USP) <US>
Other DBs
CAS: 357-07-3
PubChem: 7847909
ChEBI: 7866
ChEMBL: CHEMBL1200794
LigandBox: D00844
NIKKAJI: J219.953J
LinkDB
KCF data

ATOM        23
            1   X   Cl   28.8996  -15.0125
            2   C1z C    23.5917  -17.6850
            3   C8y C    23.5857  -16.3337
            4   C1z C    24.7573  -18.3521
            5   C1y C    22.4376  -18.3637
            6   C8y C    22.4201  -15.6610
            7   C8y C    24.7515  -15.6610
            8   C1y C    25.9174  -17.6677
            9   C1x C    24.7630  -19.6859
            10  O1a O    25.9174  -19.2917
            11  O2x O    21.7357  -17.0300
            12  C5x C    22.4433  -19.6975
            13  C8y C    22.4201  -14.3156
            14  C1x C    25.9174  -16.3278
            15  C8x C    24.7515  -14.3156
            16  N1y N    27.0771  -18.3403
            17  C1x C    23.6090  -20.3645
            18  O5x O    21.2660  -20.3586
            19  C8x C    23.5857  -13.6429
            20  O1a O    21.2486  -13.6429
            21  C1a C    28.4226  -18.3403
            22  C1x C    27.0771  -17.0172
            23  C1x C    24.7979  -16.9886
BOND        26
            1     2   3 1
            2     2   4 1
            3     2   5 1
            4     3   6 1
            5     3   7 2
            6     4   8 1
            7     4   9 1
            8     4  10 1 #Up
            9     5  11 1 #Down
            10    5  12 1
            11    6  13 2
            12    7  14 1
            13    7  15 1
            14    8  16 1 #Up
            15    9  17 1
            16   12  18 2
            17   13  19 1
            18   13  20 1
            19   16  21 1
            20    6  11 1
            21    8  14 1
            22   12  17 1
            23   15  19 2
            24    2  23 1 #Up
            25   23  22 1
            26   16  22 1 #Up

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