KEGG   DRUG: GantenerumabHelp
Entry
D09713                      Drug                                   

Name
Gantenerumab (USAN/INN);
Gantenerumab (genetical recombination) (JAN)
Formula
C6496H10072N1740O2024S42
Exact mass
146184.6967
Mol weight
146274.6525
Sequence
(gamma1-heavy chain) QVELVESGGG LVQPGGSLRL SCAASGFTFS SYAMSWVRQA
PGKGLEWVSA INASGTRTYY ADSVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARGK
GNTHKPYGYV RYFDVWGQGT LVTVSSASTK GPSVFPLAPS SKSTSGGTAA LGCLVKDYFP
EPVTVSWNSG ALTSGVHTFP AVLQSSGLYS LSSVVTVPSS SLGTQTYICN VNHKPSNTKV
DKKVEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP
EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP
IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY
KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK
(kappa-light chain) DIVLTQSPAT LSLSPGERAT LSCRASQSVS SSYLAWYQQK
PGQAPRLLIY GASSRATGVP ARFSGSGSGT DFTLTISSLE PEDFATYYCL QIYNMPITFG
QGTKVEIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS
QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC
  Type
Peptide
Class
Neuropsychiatric agent
 DG01968  Agents for Alzheimer-type dementia
Efficacy
Dementia therapeutic agent
Comment
Monoclonal antibody
Treatment of Alzheimer's disease
Target
beta-amyloid
Structure map
map07056  Agents for Alzheimer-type dementia
Other DBs
CAS: 1043556-46-2
PubChem: 124490453
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