KEGG   GLYCAN: G00060Help
Entry
G00060                      Glycan                                 

Name
III3Fuc-nLc4Cer;
III3-a-Fuc-nLc4Cer;
Lacto-N-fucopentaosyl III ceramide;
LNF III cer;
SSEA-1
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (LFuc)1 (Cer)1
Mass
835.8 (Cer)
Structure
KCF fileKCaMSNFG
Reaction
Pathway
map00601  Glycosphingolipid biosynthesis - lacto and neolacto series
map01100  Metabolic pathways
Enzyme
2.4.1.65        2.4.1.152       2.4.1.-
Brite
Lipids [BR:br08002]
 SP  Sphingolipids
  SP05 Neutral glycosphingolipids
   SP0505 Galb1-4GlcNAcb1-3Galb1-4Glc- (Neolacto series)
    G00060  Gal-beta1->4(Fuc-alpha1->3)GlcNAc-beta1->3Gal-beta1->4Glc-beta1->1'Cer (SSEA-1)
BRITE hierarchy
Reference
1  [PMID:9111138]
  Authors
Henry S, Jovall PA, Ghardashkhani S, Elmgren A, Martinsson T, Larson G, Samuelsson B.
  Title
Structural and immunochemical identification of Le(a), Le(b), H type 1, and related glycolipids in small intestinal mucosa of a group O Le(a-b-) nonsecretor.
  Journal
Glycoconj J 14:209-23 (1997)
Reference
2  [PMID:2960671]
  Authors
Holmes EH, Hakomori S, Ostrander GK.
  Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 262:15649-58 (1987)
Reference
3  [PMID:2430018]
  Authors
Umeda M, Diego I, Marcus DM.
  Title
The occurrence of anti-3-fucosyllactosamine antibodies and their cross-reactive idiotopes in preimmune and immune mouse sera.
  Journal
J Immunol 137:3264-9 (1986)
Other DBs
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KCF data Show

NODE        6
            1   Cer        13     0
            2   Glc         7     0
            3   Gal         1     0
            4   GlcNAc     -6     0
            5   Gal       -13     4
            6   LFuc      -14    -4
EDGE        5
            1     2:b1    1:1  
            2     3:b1    2:4  
            3     4:b1    3:3  
            4     5:b1    4:4  
            5     6:a1    4:3

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