KEGG   ORTHOLOGY: K00002
Entry
K00002                      KO                                     

Name
AKR1A1, adh
Definition
alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
Pathway
ko00010  Glycolysis / Gluconeogenesis
ko00040  Pentose and glucuronate interconversions
ko00053  Ascorbate and aldarate metabolism
ko00561  Glycerolipid metabolism
ko00930  Caprolactam degradation
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
ko01240  Biosynthesis of cofactors
Module
M00014  Glucuronate pathway (uronate pathway)
M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
   00040 Pentose and glucuronate interconversions
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
   00053 Ascorbate and aldarate metabolism
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
  09111 Xenobiotics biodegradation and metabolism
   00930 Caprolactam degradation
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.2  alcohol dehydrogenase (NADP+)
     K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K00002  AKR1A1, adh; alcohol dehydrogenase (NADP+)
Other DBs
RN: R00746 R01041 R01481 R05231
COG: COG0656
GO: 0008106
Genes
HSA: 10327(AKR1A1)
PTR: 741418(AKR1A1)
PPS: 100990701(AKR1A1)
GGO: 101124639(AKR1A1)
PON: 100173796(AKR1A1)
NLE: 100581229(AKR1A1)
MCC: 693380(AKR1A1)
MCF: 102143796(AKR1A1)
CSAB: 103224909(AKR1A1)
RRO: 104662135(AKR1A1)
RBB: 108520216 108535599(AKR1A1)
CJC: 100404430(AKR1A1)
SBQ: 101054314(AKR1A1)
MMU: 58810(Akr1a1)
MCAL: 110292309(Akr1a1)
MPAH: 110322723(Akr1a1)
RNO: 78959(Akr1a1)
MUN: 110546525(Akr1a1)
CGE: 100689106(Akr1a1)
NGI: 103728426 103737782(Akr1a1)
HGL: 101710959(Akr1a1)
CCAN: 109698640(Akr1a1)
TUP: 102474258(AKR1A1)
CFA: 610537(AKR1A1)
VVP: 112914782(AKR1A1)
AML: 100466911(AKR1A1)
UMR: 103670772(AKR1A1)
UAH: 113254739(AKR1A1)
ORO: 101378260(AKR1A1)
ELK: 111143518
FCA: 101091464(AKR1A1)
PTG: 102953655(AKR1A1)
PPAD: 109266967(AKR1A1)
AJU: 106970247(AKR1A1)
BTA: 618607(AKR1A1)
BOM: 102278148(AKR1A1)
BIU: 109556353(AKR1A1)
BBUB: 102399958(AKR1A1)
CHX: 102181747(AKR1A1)
OAS: 101121637(AKR1A1)
SSC: 396924(AKR1A1)
CFR: 102508336(AKR1A1)
CDK: 105090867(AKR1A1)
BACU: 103012987(AKR1A1)
LVE: 103076421(AKR1A1)
OOR: 101275575(AKR1A1)
DLE: 111175752(AKR1A1)
PCAD: 102977999(AKR1A1)
ECB: 100052360(AKR1A1)
EPZ: 103551882(AKR1A1)
EAI: 106826141(AKR1A1)
MYB: 102261432(AKR1A1)
MYD: 102763234(AKR1A1)
MNA: 107526721(AKR1A1)
HAI: 109375511(AKR1A1)
DRO: 112314630(AKR1A1)
PALE: 102889346(AKR1A1)
RAY: 107506894(AKR1A1)
MJV: 108401896(AKR1A1)
MDO: 100024617(AKR1A1)
SHR: 100933920(AKR1A1)
PCW: 110209283(AKR1A1)
OAA: 100076515(AKR1A1)
GGA: 424599(AKR1A1)
MGP: 100547531(AKR1A1)
CJO: 107317439(AKR1A1)
NMEL: 110402948(AKR1A1)
APLA: 101804381(AKR1A1)
ACYG: 106033070(AKR1A1)
TGU: 100220342(AKR1A1)
LSR: 110469644(AKR1A1)
SCAN: 103814983(AKR1A1)
GFR: 102039134(AKR1A1)
FAB: 101814677(AKR1A1)
PHI: 102111381(AKR1A1)
PMAJ: 107208007(AKR1A1)
CCAE: 111933109(AKR1A1)
CCW: 104695240(AKR1A1)
ETL: 114062136(AKR1A1)
FPG: 101914281(AKR1A1)
FCH: 102058485(AKR1A1)
CLV: 102086095(AKR1A1)
EGZ: 104126259(AKR1A1)
NNI: 104015414(AKR1A1)
ACUN: 113482955(AKR1A1)
PADL: 103919132(AKR1A1)
AAM: 106485925(AKR1A1)
ASN: 102381941(AKR1A1)
AMJ: 102560934(AKR1A1)
PSS: 102453813(AKR1A1)
CMY: 102932885(AKR1A1)
CPIC: 101951623(AKR1A1)
ACS: 100553683(akr1a1)
PVT: 110073749(AKR1A1)
PBI: 103067202(AKR1A1)
PMUR: 107283429(AKR1A1)
TSR: 106546846(AKR1A1)
PMUA: 114599099(AKR1A1)
GJA: 107107909(AKR1A1)
XLA: 108715556(akr1a1.S) 444488(akr1a1.L)
XTR: 548891(akr1a1)
NPR: 108802784(AKR1A1)
DRE: 445326(akr1a1a) 799805(akr1a1b)
IPU: 100528626(akr1a1)
PHYP: 113538367(akr1a1)
AMEX: 103028964(akr1a1)
EEE: 113586153(akr1a1)
TRU: 101075563 101077149(akr1a1)
LCO: 104921221 104937447(akr1a1)
NCC: 104947807 104956412(akr1a1)
MZE: 101467748 101476039(akr1a1)
ONL: 100534433 100697867(akr1a1)
OLA: 101172969(akr1a1) 101175168
XMA: 102234019 102236025(akr1a1)
XCO: 114151486(akr1a1) 114154606
PRET: 103464015(akr1a1) 103470380
CVG: 107083683 107091692(akr1a1)
NFU: 107387343(akr1a1) 107393930
KMR: 108234548 108244962(akr1a1)
ALIM: 106521742 106530424(akr1a1)
AOCE: 111576142(akr1a1) 111584853
CSEM: 103398194 103398807(akr1a1)
POV: 109625235(akr1a1) 109638162
LCF: 108878174 108878819(akr1a1)
SDU: 111231669 111232002(akr1a1)
SLAL: 111660303 111671969(akr1a1)
HCQ: 109506839(akr1a1) 109514126
BPEC: 110156675 110168991(akr1a1)
MALB: 109965784(akr1a1)
SASA: 106560437(AK1A1) 106580289 106584055(AK1A1)
ELS: 105005908(akr1a1) 105025564
SFM: 108935416(akr1a1) 108938083
PKI: 111834770(akr1a1) 111856600
LCM: 102347995 102356304(AKR1A1)
CMK: 103176872 103182771(akr1a1)
RTP: 109916604(akr1a1) 109927014
SPU: 587281
DME: Dmel_CG2767(CG2767)
DER: 6553578
DSE: 6614318
DSI: Dsimw501_GD19441(Dsim_GD19441)
DAN: 6499665
DSR: 110188410
DPE: 6587327
DMN: 108154723
DAZ: 108621143
DNV: 108659544
DHE: 111594614
MDE: 101897237
LCQ: 111689702
AAG: 5577411
HST: 105187493
BMOR: 101746883
BMAN: 114249313
HAW: 110378598
TNL: 113498726
PXY: 105398444
API: 100159357
CSCU: 111634554
PTEP: 107447942
BMY: Bm1_28070
MYI: 110455981
EGL: EGR_03866
ADF: 107338307
ATH: AT2G37790(AKR4C10) AT5G01670
LJA: Lj0g3v0141139.1(Lj0g3v0141139.1) Lj1g3v2393300.1(Lj1g3v2393300.1) Lj1g3v3443800.1(Lj1g3v3443800.1) Lj3g3v1591680.1(Lj3g3v1591680.1) Lj4g3v0473890.1(Lj4g3v0473890.1) Lj4g3v0484310.1(Lj4g3v0484310.1) Lj5g3v0110960.1(Lj5g3v0110960.1)
DOSA: Os01t0847600-01(Os01g0847600) Os01t0847700-01(Os01g0847700) Os05t0456200-00(Os05g0456200) Os05t0456300-01(Os05g0456300) Os05t0474600-01(Os05g0474600)
ATS: 109742647(LOC109742647) 109745552(LOC109745552) 109748209(LOC109748209) 109751157(LOC109751157) 109751158(LOC109751158) 109751159(LOC109751159) 109751161(LOC109751161) 109751162(LOC109751162) 109751164(LOC109751164) 109751166(LOC109751166) 109760025(LOC109760025) 109760026(LOC109760026) 109768050(LOC109768050) 109786214(LOC109786214)
ZMA: 100037812(pco147797a) 100194348 100279403(cl25115_1) 100381673(TIDP2673) 100857058 103625686 103630432
MNG: MNEG_0815
SCE: YCR105W(ADH7) YMR318C(ADH6)
ERC: Ecym_1093
KMX: KLMA_80339(ADH6)
NCS: NCAS_0C03020(NCAS0C03020) NCAS_0D01220(NCAS0D01220)
NDI: NDAI_0A08470(NDAI0A08470) NDAI_0G04880(NDAI0G04880) NDAI_0H02940(NDAI0H02940) NDAI_0H02950(NDAI0H02950)
TPF: TPHA_0A00140(TPHA0A00140) TPHA_0F02090(TPHA0F02090) TPHA_0J00170(TPHA0J00170)
TBL: TBLA_0A02730(TBLA0A02730) TBLA_0A06640(TBLA0A06640)
TDL: TDEL_0E00230(TDEL0E00230) TDEL_0F02300(TDEL0F02300)
KAF: KAFR_0A08730(KAFR0A08730) KAFR_0B00190(KAFR0B00190) KAFR_0C01550(KAFR0C01550) KAFR_0H03770(KAFR0H03770)
PIC: PICST_29079(ADH4) PICST_31312(ADH5) PICST_34588(ADH6) PICST_45137(ADH7) PICST_88760(ADH3)
SPAA: SPAPADRAFT_63283(ADH6)
CAL: CAALFM_C602480WA(CaO19.5517)
SLB: AWJ20_360(ADH6)
NTE: NEUTE1DRAFT63362(NEUTE1DRAFT_63362) NEUTE1DRAFT68571(NEUTE1DRAFT_68571) NEUTE1DRAFT83201(NEUTE1DRAFT_83201)
ANG: ANI_1_1690074(An08g01520) ANI_1_3340014(An01g14380) ANI_1_358144(An16g02510) ANI_1_562044(An05g02070) ANI_1_800034(An03g06430) ANI_1_92104(An12g00670)
MRT: MRET_1998
EHI: EHI_039190(73.t00013) EHI_198760(34.t00053)
TCR: 504425.60
AHN: NCTC12129_03662(dkgA_2)
PHEI: NCTC12003_03169(dkgA)
CBD: CBUD_1937
CBG: CbuG_1847
NTT: TAO_0889
ABO: ABO_2414(AKR1A1)
ADI: B5T_00396(akr1a1)
AXE: P40_01805
BPH: Bphy_4997
CABA: SBC2_37080
DSF: UWK_02985
PSF: PSE_5041
CBEI: LF65_04156
CCE: Ccel_1009
CSS: Cst_c01000(dkgA)
CSD: Clst_0095
RUM: CK1_37840
ROB: CK5_18630
RTO: RTO_08790
PUF: UFO1_2988
KRA: Krad_3571
SYN: slr0942
SYY: SYNGTS_1828(slr0942)
SYT: SYNGTI_1828(slr0942)
SYS: SYNPCCN_1827(slr0942)
SYQ: SYNPCCP_1827(slr0942)
SYG: sync_0822
CYT: cce_0782
MFF: MFFC18_27540(dkgA_1)
PBAS: SMSP2_00412(dkgA)
SRU: SRU_1267
SRM: SRM_01456
FLM: MY04_0328
GFO: GFO_1874
GFL: GRFL_3606
ZPR: ZPR_1868
CBAT: M666_15795
NDO: DDD_2147
 » show all
Reference
PMID:2498333
  Authors
Bohren KM, Bullock B, Wermuth B, Gabbay KH
  Title
The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.
  Journal
J Biol Chem 264:9547-51 (1989)
  Sequence
[hsa:10327]
LinkDB

DBGET integrated database retrieval system