KEGG   ORTHOLOGY: K00011
Entry
K00011                      KO                                     

Name
AKR1B
Definition
aldehyde reductase [EC:1.1.1.21]
Pathway
ko00040  Pentose and glucuronate interconversions
ko00051  Fructose and mannose metabolism
ko00052  Galactose metabolism
ko00561  Glycerolipid metabolism
ko00790  Folate biosynthesis
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    K00011  AKR1B; aldehyde reductase
   00051 Fructose and mannose metabolism
    K00011  AKR1B; aldehyde reductase
   00052 Galactose metabolism
    K00011  AKR1B; aldehyde reductase
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    K00011  AKR1B; aldehyde reductase
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K00011  AKR1B; aldehyde reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.21  aldose reductase
     K00011  AKR1B; aldehyde reductase
Other DBs
RN: R01036 R01041 R01093 R01095 R01431 R01758 R01759 R01787 R02531 R02577 R04285 R11764
COG: COG0656
GO: 0004032
Genes
HSA: 231(AKR1B1) 57016(AKR1B10)
PTR: 463867(AKR1B10) 736853(AKR1B15) 737737(AKR1B1)
PPS: 100967410(AKR1B15) 100975756(AKR1B10) 100996067(AKR1B1)
GGO: 101144124(AKR1B1) 101145822(AKR1B10) 115935241
PON: 100444840(AKR1B1) 100445201(AKR1B10) 100445574
NLE: 100585224(AKR1B1) 100585902(AKR1B10)
MCC: 106996453 705957(AKR1B1) 706528 706646 713150
MCF: 101865018 101926277(AKR1B1) 102120093 102121104 102121743 102122400 102122997(AKR1B10)
CSAB: 103226928(AKR1B1) 103226929 103226931 103226932
RRO: 104657859 104657860 104657861 104657863(AKR1B1)
RBB: 108515792(AKR1B1) 108539216(AKR1B10)
CJC: 100387030(AKR1B10) 100387387(AKR1B1)
SBQ: 101031103(AKR1B1) 101045366
MMU: 11677(Akr1b3) 11997(Akr1b7) 14187(Akr1b8) 67861(Akr1b10)
MCAL: 110295915(Akr1b10) 110295916 110296013(Akr1b1)
RNO: 116463(Akr1b7) 24192(Akr1b1) 286921(Akr1b8) 296972(Akr1b10)
CGE: 100689318(Akr1b8) 100751272(Akr1b1) 100757262 100758120
NGI: 103736560(Akr1b10) 103736561(Akr1b1)
HGL: 101705915 101706493(Akr1b10) 101720124(Akr1b1)
OCU: 100009122(AKR1B1) 100341518(AKR1B10)
TUP: 102468970 102469817 102494851(AKR1B1) 102495669(AKR1B10)
CFA: 607537(AKR1B1)
VVP: 112928987(AKR1B1)
AML: 100479370(AKR1B1)
UMR: 103678252(AKR1B1)
UAH: 113264345(AKR1B1)
ORO: 101366220(AKR1B1)
ELK: 111152013
FCA: 101095406(AKR1B1)
PTG: 102953851(AKR1B1)
PPAD: 109269032(AKR1B1)
AJU: 106975707
BTA: 317748(AKR1B1) 525193(AKR1B10) 616199
BOM: 102283791(AKR1B1) 102284069(AKR1B10) 102286471
BIU: 109557651(AKR1B1) 109557652(AKR1B10)
BBUB: 102392991(AKR1B1) 102402798(AKR1B10)
CHX: 102187190(AKR1B1) 102187646(AKR1B10)
OAS: 101107697 101120824(AKR1B1)
SSC: 396816(AKR1B1)
CFR: 102513557(AKR1B1)
CDK: 105085402(AKR1B1)
BACU: 103010471(AKR1B1)
LVE: 103088864(AKR1B1)
OOR: 101287897(AKR1B1)
DLE: 111178199(AKR1B1)
PCAD: 102985317(AKR1B1)
ECB: 100065145(AKR1B1)
EPZ: 103551318(AKR1B1)
EAI: 106830010(AKR1B1)
MYB: 102254354(AKR1B10) 102256742(AKR1B1)
MYD: 102753092(AKR1B1) 102772161(AKR1B10)
MNA: 107544356 107544458(AKR1B10)
HAI: 109389373(AKR1B1)
DRO: 112297391 112299891(AKR1B1)
PALE: 102887071(AKR1B1)
MJV: 108400068(AKR1B1)
MDO: 100021757(AKR1B1)
SHR: 100923275
PCW: 110219188(AKR1B1)
GGA: 395338(AKR1B10L2) 418169(AKR1B10L1) 418170(AKR1B10L3) 418171(AKR1E2) 425137(AKR1B1L) 772271(AKR1B10L4)
AMJ: 102567910 102569073(AKR1B1)
PVT: 110088824
PBI: 103050065
PMUR: 107294356
TSR: 106551076
PMUA: 114605229
GJA: 107108024
XLA: 108704367(akr1b1.L) 398904(akr1b1.S)
XTR: 496546(akr1b1)
NPR: 108789955(AKR1B1)
DRE: 553452(akr1b1.2)
SGH: 107587162
IPU: 100528852(akr1b1)
AMEX: 103035339
EEE: 113587784
TRU: 101070998
LCO: 109138870
NCC: 104960079
MZE: 101477205
ONL: 100700843
OLA: 101167259
XMA: 102229660
XCO: 114161093
PRET: 103459462
CVG: 107098428
NFU: 107384342
KMR: 108240995(akr1b1)
ALIM: 106523520
AOCE: 111563385
CSEM: 107988900
POV: 109632879
LCF: 108887379
SDU: 111224606
SLAL: 111663697
HCQ: 109523886
BPEC: 110155854
MALB: 109968263
SASA: 106576053 106609240(ALDR)
ELS: 105029080
SFM: 108920995
LCM: 102361295(AKR1B1)
DME: Dmel_CG10638(CG10638) Dmel_CG10863(CG10863) Dmel_CG12766(CG12766) Dmel_CG40064(ARY) Dmel_CG6083(CG6083) Dmel_CG6084(Akr1B) Dmel_CG9436(CG9436)
DSI: Dsimw501_GD10303(Dsim_GD10303) Dsimw501_GD12788(Dsim_GD12788) Dsimw501_GD12789(Dsim_GD12789) Dsimw501_GD13308(Dsim_GD13308) Dsimw501_GD13309(Dsim_GD13309)
BIM: 100748867
BTER: 100652140
OBB: 114883145
BMOR: 101736565
BMAN: 114248479
PMAC: 106709371
HAW: 110380546
DNX: 107169883
CEL: CELE_Y39G8B.1(Y39G8B.1)
CBR: CBG20740
BMY: Bm1_43535
SHX: MS3_00286
DDI: DDB_G0268058(alrC) DDB_G0285053(alrB) DDB_G0293850(alrA)
EHI: EHI_029620(466.t00004)
 » show all
Reference
PMID:2498333
  Authors
Bohren KM, Bullock B, Wermuth B, Gabbay KH
  Title
The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.
  Journal
J Biol Chem 264:9547-51 (1989)
  Sequence
[hsa:231]
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