KEGG   ORTHOLOGY: K00182
Entry
K00182                      KO                                     

Name
WNT2
Definition
wingless-type MMTV integration site family, member 2
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04390 Hippo signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   04150 mTOR signaling pathway
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05205 Proteoglycans in cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05226 Gastric cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05217 Basal cell carcinoma
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05224 Breast cancer
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00182  WNT2; wingless-type MMTV integration site family, member 2
   05022 Pathways of neurodegeneration - multiple diseases
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00182  WNT2; wingless-type MMTV integration site family, member 2
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00182  WNT2; wingless-type MMTV integration site family, member 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00182  WNT2; wingless-type MMTV integration site family, member 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00182  WNT2; wingless-type MMTV integration site family, member 2
Genes
HSA: 7472(WNT2) 7482(WNT2B)
PTR: 457103(WNT2B) 463673(WNT2)
PPS: 100983371(WNT2B) 100990322(WNT2)
GGO: 101129834(WNT2B) 101130779(WNT2)
PON: 100137034(WNT2) 100460815(WNT2B)
NLE: 100600353(WNT2) 100607954(WNT2B)
MCC: 704991(WNT2) 705773(WNT2B)
MCF: 102129174(WNT2) 102130917(WNT2B)
CSAB: 103224207(WNT2B) 103226775(WNT2)
RRO: 104658925(WNT2B) 104682628(WNT2)
RBB: 108526536(WNT2) 108528095(WNT2B)
CJC: 100395234(WNT2B) 100411308(WNT2)
SBQ: 101037307(WNT2) 101051098(WNT2B)
MMU: 22413(Wnt2) 22414(Wnt2b)
MCAL: 110291476(Wnt2b) 110296313(Wnt2)
MPAH: 110316416(Wnt2) 110320339(Wnt2b)
RNO: 114487(Wnt2) 116466(Wnt2b)
MUN: 110546992(Wnt2b) 110548404(Wnt2)
CGE: 100752722(Wnt2) 100761413(Wnt2b)
NGI: 103734912(Wnt2b) 103737375(Wnt2)
HGL: 101704935(Wnt2b) 101723565(Wnt2)
CCAN: 109681721(Wnt2b) 109684416(Wnt2)
OCU: 100126569(WNT2) 100349847(WNT2B)
TUP: 102479831(WNT2B) 102483867(WNT2)
CFA: 483220(WNT2B) 612141(WNT2)
VVP: 112907938(WNT2B) 112929869(WNT2)
AML: 100480237(WNT2) 100481665(WNT2B)
UMR: 103675048(WNT2B) 103676588(WNT2)
UAH: 113244420(WNT2B) 113263284(WNT2)
ORO: 101364222(WNT2) 101373643(WNT2B)
FCA: 101080904(WNT2B) 493672(WNT2)
PTG: 102954954(WNT2) 102963336(WNT2B)
PPAD: 109248384(WNT2) 109272063(WNT2B)
AJU: 106969623(WNT2B) 106970665(WNT2)
BTA: 445420(WNT2B) 493729(WNT2)
BOM: 102285570(WNT2B) 102288008(WNT2)
BIU: 109555924(WNT2B) 109557407(WNT2)
BBUB: 102392459(WNT2) 102401777(WNT2B)
CHX: 102180281(WNT2) 102182009(WNT2B)
OAS: 100126577(WNT2) 101116782(WNT2B)
SSC: 100516839(WNT2) 100520560(WNT2B)
CFR: 102505341(WNT2) 102517871(WNT2B)
CDK: 105085323(WNT2) 105102049(WNT2B)
BACU: 103003752(WNT2) 103013943(WNT2B)
LVE: 103089326(WNT2) 103089709(WNT2B)
OOR: 101279049(WNT2) 101289035(WNT2B)
DLE: 111179238(WNT2) 111180026(WNT2B)
PCAD: 102984033(WNT2) 102988919(WNT2B)
ECB: 100056092(WNT2) 100063931(WNT2B)
EPZ: 103541803(WNT2B) 103550603(WNT2)
EAI: 106828591(WNT2B) 106829346(WNT2)
MYB: 102255951(WNT2B) 102261227(WNT2)
MYD: 102752980(WNT2) 102765024(WNT2B)
MNA: 107524863(WNT2) 107545293(WNT2B)
HAI: 109389334(WNT2) 109391554(WNT2B)
DRO: 112300214(WNT2) 112314027(WNT2B)
PALE: 102880959(WNT2B) 102885080(WNT2)
RAY: 107499803(WNT2B) 107505364(WNT2)
MJV: 108393959(WNT2) 108398947(WNT2B)
LAV: 100653551(WNT2B) 100657046(WNT2)
MDO: 100011991(WNT2) 100033140(WNT2B)
SHR: 100918306(WNT2) 100918389(WNT2B)
PCW: 110200646(WNT2) 110218849(WNT2B)
OAA: 100077640(WNT2) 100087253(WNT2B)
GGA: 374243(WNT2B) 417769(WNT2)
MGP: 100545665(WNT2) 100551435(WNT2B)
CJO: 107309102(WNT2) 107324859(WNT2B)
NMEL: 110388347(WNT2B) 110392596(WNT2)
APLA: 101799824(WNT2) 101800865(WNT2B)
ACYG: 106041264(WNT2B) 106042052(WNT2)
TGU: 100221216(WNT2) 100227493(WNT2B)
LSR: 110475395(WNT2B) 110483525(WNT2)
SCAN: 103813467(WNT2) 103823266(WNT2B)
GFR: 102039793(WNT2B) 102040836(WNT2)
FAB: 101807109(WNT2B) 101821440(WNT2)
PHI: 102099201(WNT2) 102111953(WNT2B)
PMAJ: 107204737(WNT2) 107215039(WNT2B)
CCAE: 111931532(WNT2) 111939776(WNT2B)
CCW: 104692318(WNT2B) 104698447(WNT2)
ETL: 114062355(WNT2) 114063117(WNT2B)
FPG: 101916797(WNT2B) 101924187(WNT2)
FCH: 102050583(WNT2) 102054880(WNT2B)
EGZ: 104126790(WNT2B) 104133417(WNT2)
NNI: 104010320(WNT2B) 104013623(WNT2)
ACUN: 113488894(WNT2B) 113491227(WNT2)
PADL: 103917006(WNT2) 103923556(WNT2B)
AAM: 106485278(WNT2B) 106488127(WNT2)
ASN: 102377917(WNT2B) 102388685(WNT2)
AMJ: 102569359(WNT2) 102575620(WNT2B)
PSS: 102443393(WNT2B) 102448332(WNT2)
CMY: 102929895(WNT2B) 102936696(WNT2)
CPIC: 101932483(WNT2) 101949084(WNT2B)
ACS: 100559857(wnt2b)
PVT: 110072347(WNT2B)
PBI: 103048288(WNT2B)
PMUR: 107300573(WNT2B)
TSR: 106548888(WNT2B)
PMUA: 114599371(WNT2B)
GJA: 107110304(WNT2B)
XLA: 108711137 108713107 378566(wnt2b.L)
XTR: 100038261(wnt2) 100491761(wnt2b)
NPR: 108790556(WNT2B) 108802068(WNT2)
DRE: 30127(wnt2) 359837(wnt2ba) 556087(wnt2bb)
IPU: 108263957(wnt2) 108266047(wnt2b) 108271793
PHYP: 113528241 113529774(wnt2b) 113534315(wnt2)
AMEX: 103029625 103033339(wnt2) 103046094(wnt2b)
EEE: 113572035(wnt2b) 113573613(wnt2) 113583078
ONL: 100693354 100693728(wnt2b) 100710509(wnt2)
PRET: 103464374(wnt2b) 103465636(wnt2) 103467401
CVG: 107083201(wnt2) 107091405 107103507(wnt2b)
CSEM: 103379582(wnt2) 103384543 103386704(wnt2b)
LCF: 108889451(wnt2b) 108893965(wnt2) 108902118
SDU: 111218939(wnt2b) 111220512(wnt2) 111239696
SLAL: 111669004(wnt2b) 111669668 111672160(wnt2)
LCM: 102345664(WNT2) 102352078(WNT2B)
CMK: 103179360(wnt2) 103182404(wnt2b)
RTP: 109915129 109917718(wnt2)
BFO: 118416575
CIN: 778720
APLC: 110984921
SKO: 100303493(Wnt2)
FCD: 110856954
DPX: DAPPUDRAFT_43478(WNT2)
CSCU: 111625291
PTEP: 107442876
BMY: Bm1_22145
TSP: Tsp_07695
PCAN: 112572019
CRG: 105340175
MYI: 110456287
OBI: 106880752
LAK: 106154358
SHX: MS3_03376
EGL: EGR_03800
NVE: 5513514
EPA: 110234822
HMG: 100214868(hywnt7) 100215038(hywnt9/10a)
 » show all
Reference
  Authors
Kawakami Y, Capdevila J, Buscher D, Itoh T, Rodriguez Esteban C, Izpisua Belmonte JC
  Title
WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.
  Journal
Cell 104:891-900 (2001)
DOI:10.1016/S0092-8674(01)00285-9
  Sequence
[gga:374243]
Reference
PMID:2971536
  Authors
Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS, et al.
  Title
Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.
  Journal
EMBO J 7:1743-8 (1988)
DOI:10.1002/j.1460-2075.1988.tb03003.x
  Sequence
[hsa:7472]
Reference
PMID:8761309
  Authors
Katoh M, Hirai M, Sugimura T, Terada M
  Title
Cloning, expression and chromosomal localization of Wnt-13, a novel member of the Wnt gene family.
  Journal
Oncogene 13:873-6 (1996)
  Sequence
[hsa:7482]
LinkDB

KEGG   ORTHOLOGY: K00312
Entry
K00312                      KO                                     

Name
WNT3
Definition
wingless-type MMTV integration site family, member 3
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00636  Tetra-amelia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   04390 Hippo signaling pathway
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   04150 mTOR signaling pathway
    K00312  WNT3; wingless-type MMTV integration site family, member 3
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00312  WNT3; wingless-type MMTV integration site family, member 3
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00312  WNT3; wingless-type MMTV integration site family, member 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05206 MicroRNAs in cancer
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05205 Proteoglycans in cancer
    K00312  WNT3; wingless-type MMTV integration site family, member 3
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05226 Gastric cancer
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05217 Basal cell carcinoma
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05224 Breast cancer
    K00312  WNT3; wingless-type MMTV integration site family, member 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00312  WNT3; wingless-type MMTV integration site family, member 3
   05022 Pathways of neurodegeneration - multiple diseases
    K00312  WNT3; wingless-type MMTV integration site family, member 3
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00312  WNT3; wingless-type MMTV integration site family, member 3
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00312  WNT3; wingless-type MMTV integration site family, member 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00312  WNT3; wingless-type MMTV integration site family, member 3
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00312  WNT3; wingless-type MMTV integration site family, member 3
Genes
HSA: 7473(WNT3) 89780(WNT3A)
PTR: 100615247(WNT3A) 107966366(WNT3)
PPS: 100977143(WNT3A) 100992553(WNT3)
GGO: 101133265(WNT3) 101148241 115931239(WNT3A)
PON: 100431449(WNT3) 100448240(WNT3A)
NLE: 100599381(WNT3) 100606846(WNT3A)
MCC: 696200(WNT3A) 716909(WNT3)
MCF: 102129654(WNT3) 102131688(WNT3A)
CSAB: 103229967(WNT3A) 103243255(WNT3)
RRO: 104672034(WNT3A) 104682399(WNT3)
RBB: 108529362(WNT3) 108536790(WNT3A)
CJC: 100385309(WNT3A) 100398579(WNT3)
SBQ: 101035500(WNT3A) 101048838(WNT3)
MMU: 22415(Wnt3) 22416(Wnt3a)
MCAL: 110304911(Wnt3) 110305853(Wnt3a)
MPAH: 110331285(Wnt3a) 110331952(Wnt3)
RNO: 24882(Wnt3) 303181(Wnt3a)
MUN: 110545664(Wnt3)
CGE: 100764164(Wnt3a) 100774849
NGI: 103724772(Wnt3) 103739037(Wnt3a)
HGL: 101716074(Wnt3a) 101724651(Wnt3)
CCAN: 109677070(Wnt3a) 109684805(Wnt3)
OCU: 100009033(WNT3) 100354583(WNT3A)
TUP: 102489001(WNT3) 102501628(WNT3A)
CFA: 482208(WNT3A) 609107(WNT3)
VVP: 112911970(WNT3A) 112920633(WNT3)
AML: 100471555(WNT3) 100473835(WNT3A)
UMR: 103665889(WNT3) 103678870(WNT3A)
UAH: 113247468(WNT3A) 113265670(WNT3)
ORO: 101374826(WNT3) 101381764(WNT3A)
FCA: 101080607(WNT3A) 101088533(WNT3)
PTG: 102950040(WNT3A) 102962551(WNT3)
PPAD: 109259603 109259748(WNT3)
AJU: 106985206(WNT3A) 106988834(WNT3)
BTA: 522467(WNT3A) 540753(WNT3)
BOM: 102275609(WNT3A) 102281377(WNT3)
BIU: 109561352(WNT3A) 109573450(WNT3)
BBUB: 102410425(WNT3A) 102413171(WNT3)
CHX: 102169703(WNT3) 102184049(WNT3A)
OAS: 101120096(WNT3) 101123374(WNT3A)
SSC: 100514950(WNT3A) 100519512(WNT3)
CFR: 102513236(WNT3A) 102513805(WNT3)
CDK: 105090437(WNT3) 105094160(WNT3A)
BACU: 103015001(WNT3) 103020927(WNT3A)
LVE: 103081536(WNT3) 103087738(WNT3A)
OOR: 101279993(WNT3) 101282623(WNT3A)
DLE: 111169289(WNT3A) 111182576(WNT3)
PCAD: 102986761(WNT3A) 102993662(WNT3)
ECB: 100049880(WNT3) 100061145(WNT3A)
EPZ: 103552917(WNT3) 103565876(WNT3A)
EAI: 106821809(WNT3A) 106836509(WNT3)
MYB: 102240785(WNT3) 102244362(WNT3A)
MYD: 102767612(WNT3) 102774271(WNT3A)
MNA: 107529919(WNT3A) 107530219(WNT3)
HAI: 109377253(WNT3A) 109380253(WNT3)
DRO: 112304943(WNT3A) 112316534(WNT3)
PALE: 102877979(WNT3) 102895795(WNT3A)
RAY: 107508173(WNT3) 107509667(WNT3A)
MJV: 108388938(WNT3) 108398816(WNT3A)
LAV: 100662337(WNT3A) 100663058(WNT3)
MDO: 100024702(WNT3) 100025651(WNT3A)
SHR: 100914628(WNT3A) 100935307(WNT3)
PCW: 110215655(WNT3) 110217050(WNT3A)
OAA: 100090103(WNT3A)
GGA: 374142(WNT3) 395396(WNT3A)
MGP: 100547574(WNT3A) 100549905(WNT3)
CJO: 107308854(WNT3A) 107325013(WNT3)
NMEL: 110388577(WNT3) 110395006(WNT3A)
APLA: 101800064(WNT3A) 101803262(WNT3)
ACYG: 106036872(WNT3A) 106049236(WNT3)
TGU: 100228449(WNT3A) 100231352(WNT3)
LSR: 110475618(WNT3) 110475709(WNT3A)
SCAN: 103812677(WNT3A) 103821787(WNT3)
GFR: 102040466(WNT3) 102042820(WNT3A)
FAB: 101814725(WNT3A) 101816608(WNT3)
PHI: 102111366(WNT3) 102113943(WNT3A)
PMAJ: 107201075(WNT3A) 107215195(WNT3)
CCAE: 111925567(WNT3A) 111939925(WNT3)
CCW: 104686382(WNT3A) 104698529(WNT3)
ETL: 114067377(WNT3) 114072342
FPG: 101921388(WNT3) 101924919(WNT3A)
FCH: 102047030(WNT3) 102053186(WNT3A)
CLV: 102086790(WNT3) 102092679(WNT3A)
EGZ: 104126001(WNT3) 104127432(WNT3A)
NNI: 104017398(WNT3) 104021729(WNT3A)
ACUN: 113476678(WNT3A) 113489202(WNT3)
PADL: 103920628(WNT3) 103924707(WNT3A)
AAM: 106487677(WNT3A) 106496691(WNT3)
ASN: 102368715(WNT3A) 102371877(WNT3)
AMJ: 102563237(WNT3A) 106736642(WNT3)
PSS: 102444359(WNT3) 102455431(WNT3A)
CMY: 102938454(WNT3A) 102940852(WNT3)
CPIC: 101945894(WNT3A) 101952473(WNT3)
ACS: 100555416(wnt3) 100566878(wnt3a)
PVT: 110081350(WNT3) 110085100(WNT3A)
PBI: 103053390 103061872(WNT3)
PMUR: 107286014(WNT3A) 107303109(WNT3)
TSR: 106538480(WNT3A) 106552230
PMUA: 114582049(WNT3) 114607244(WNT3A)
GJA: 107124065 107125524(WNT3)
XLA: 108700866 108718689(Xwnt-3) 378679(wnt3a.L)
XTR: 100125198(wnt3) 100487954 100488632(wnt3a)
NPR: 108788801(WNT3A) 108797411(WNT3)
DRE: 569420(wnt3) 60632(wnt3a)
IPU: 108267526(wnt3a) 108273758
PHYP: 113524110(wnt3a) 113527541
EEE: 113584183(wnt3) 113587155(wnt3a)
TRU: 101062356(wnt3a) 101069649
LCO: 104925160 109141721(wnt3a)
NCC: 104961604 104963888(wnt3a)
MZE: 101469754 101472392(wnt3a)
ONL: 100695090(wnt3a) 100707095
OLA: 101155545(wnt3a) 101174231(wnt3)
XMA: 102217483(wnt3) 102229522(wnt3a)
XCO: 114147179(wnt3a) 114152040
PRET: 103479705(wnt3a) 103481707(wnt3)
NFU: 107383855(wnt3a) 107387617
KMR: 108241634(wnt3a) 108249203
ALIM: 106521945 106533325(wnt3a)
AOCE: 111567367 111568640(wnt3a)
CSEM: 103381861 103396377(wnt3a)
POV: 109637884(wnt3a)
LCF: 108883356(wnt3a) 108892060
SDU: 111220108 111231119(wnt3a)
SLAL: 111653256(wnt3a) 111655396
BPEC: 110154316(wnt3) 110159654(wnt3a)
MALB: 109952698(wnt3a) 109962806
ELS: 105007408 105019726(wnt3a)
SFM: 108918665 108937488(wnt3a)
PKI: 111845138(wnt3) 111845850(wnt3a)
LCM: 102355315(WNT3) 102360724(WNT3A)
CMK: 103187749(wnt3)
BFO: 118405399
CIN: 445715(wnt3)
APLC: 110985570
SKO: 100303494(Wnt3)
NVE: 5515782
ADF: 107333353
PDAM: 113671394
SPIS: 111330918
DGT: 114517868
HMG: 100203050
 » show all
Reference
  Authors
Narita T, Nishimatsu S, Wada N, Nohno T
  Title
A Wnt3a variant participates in chick apical ectodermal ridge formation: distinct biological activities of Wnt3a splice variants in chick limb development.
  Journal
Dev Growth Differ 49:493-501 (2007)
DOI:10.1111/j.1440-169X.2007.00938.x
  Sequence
[gga:395396]
Reference
  Authors
Katoh M
  Title
Molecular cloning and characterization of human WNT3.
  Journal
Int J Oncol 19:977-82 (2001)
DOI:10.3892/ijo.19.5.977
  Sequence
[hsa:7473]
Reference
  Authors
Saitoh T, Hirai M, Katoh M
  Title
Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region.
  Journal
Biochem Biophys Res Commun 284:1168-75 (2001)
DOI:10.1006/bbrc.2001.5105
  Sequence
[hsa:89780]
LinkDB

KEGG   ORTHOLOGY: K00408
Entry
K00408                      KO                                     

Name
WNT4
Definition
wingless-type MMTV integration site family, member 4
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04919  Thyroid hormone signaling pathway
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00600  Mullerian agenesis
H02317  SERKAL syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04390 Hippo signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04150 mTOR signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   04916 Melanogenesis
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09158 Development and regeneration
   04360 Axon guidance
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05205 Proteoglycans in cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05226 Gastric cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05217 Basal cell carcinoma
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05224 Breast cancer
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00408  WNT4; wingless-type MMTV integration site family, member 4
   05022 Pathways of neurodegeneration - multiple diseases
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00408  WNT4; wingless-type MMTV integration site family, member 4
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00408  WNT4; wingless-type MMTV integration site family, member 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00408  WNT4; wingless-type MMTV integration site family, member 4
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00408  WNT4; wingless-type MMTV integration site family, member 4
Genes
HSA: 54361(WNT4)
PTR: 469212(WNT4)
PPS: 100992168(WNT4)
GGO: 101139722(WNT4)
PON: 100436330(WNT4)
NLE: 100604353(WNT4)
MCC: 707864(WNT4)
MCF: 102143058(WNT4)
CSAB: 103225420(WNT4)
RRO: 104663222(WNT4)
RBB: 108538467(WNT4)
CJC: 100387135(WNT4)
SBQ: 101050255(WNT4)
MMU: 22417(Wnt4)
MCAL: 110293218(Wnt4)
MPAH: 110323343(Wnt4)
RNO: 84426(Wnt4)
MUN: 110545007(Wnt4)
CGE: 100769003(Wnt4)
NGI: 103746395(Wnt4)
HGL: 101701972(Wnt4)
CCAN: 109694918(Wnt4)
OCU: 100303773(WNT4)
TUP: 102493340(WNT4)
CFA: 612367(WNT4)
VVP: 112929848(WNT4)
AML: 100468584(WNT4)
UMR: 103666795(WNT4)
UAH: 113268542(WNT4)
ORO: 101365138(WNT4)
ELK: 111154909
FCA: 101095185(WNT4)
PPAD: 109274277(WNT4)
AJU: 113599491(WNT4)
BTA: 789600(WNT4)
BOM: 102269858(WNT4)
BIU: 109576138(WNT4)
BBUB: 102405649(WNT4)
CHX: 102187819(WNT4)
OAS: 101122423(WNT4)
SSC: 100327037(WNT4)
CFR: 102522577(WNT4)
CDK: 105088869(WNT4)
BACU: 103009300(WNT4)
LVE: 103087836(WNT4)
OOR: 101270876(WNT4)
DLE: 111163319(WNT4)
PCAD: 102975662(WNT4)
ECB: 100071678(WNT4)
EPZ: 103558485(WNT4)
EAI: 106840003(WNT4)
MYB: 102240589(WNT4)
MYD: 102756007(WNT4)
MNA: 107538446(WNT4)
HAI: 109396735(WNT4)
DRO: 112299558(WNT4)
PALE: 102888866(WNT4)
RAY: 107513057(WNT4)
MJV: 108391532(WNT4)
LAV: 100664388(WNT4)
TMU: 101361433
MDO: 100026048(WNT4)
SHR: 100925510(WNT4)
PCW: 110206034(WNT4)
OAA: 100075238(WNT4)
GGA: 395561(WNT4)
MGP: 100547391(WNT4)
CJO: 107323388(WNT4)
NMEL: 110408700(WNT4)
APLA: 101791711(WNT4) 101793827
ACYG: 106047829 106049157(WNT4)
TGU: 100230804(WNT4)
LSR: 110472242(WNT4) 110480808
SCAN: 103812459 103824161(WNT4)
GFR: 102040060(WNT4) 106631805
FAB: 101806519(WNT4)
PHI: 102106062(WNT4) 102113442
PMAJ: 107212798 107213785(WNT4)
CCAE: 111938570(WNT4)
CCW: 104697541(WNT4)
ETL: 114066847(WNT4)
FPG: 101918156 101922779(WNT4)
FCH: 102048943(WNT4) 102056989
CLV: 102083488 102098373(WNT4)
EGZ: 104126592 104131863(WNT4)
NNI: 104009660 104011200(WNT4)
ACUN: 113486790 113487831(WNT4)
AAM: 106497177 106498597(WNT4)
ASN: 102367890 102376031(WNT4)
AMJ: 102561676(WNT4) 102573669
PSS: 102450128(WNT4) 102455801
CMY: 102931707 102945642(WNT4)
CPIC: 101941332(WNT4) 101944542
ACS: 100567689(wnt4)
PVT: 110086828(WNT4)
PBI: 103054356(WNT4)
PMUR: 107290018(WNT4)
TSR: 106554369(WNT4)
PMUA: 114588116 114602590(WNT4)
GJA: 107116692(WNT4)
XLA: 108697659 397706(wnt4.S)
XTR: 100491282(wnt4)
NPR: 108797396(WNT4)
DRE: 30123(wnt4) 791993(wnt4b)
IPU: 108255178(wnt4) 108263562
PHYP: 113525149 113538116(wnt4)
AMEX: 103021666 103046581(wnt4)
EEE: 113574764 113586658(wnt4)
TRU: 101067916 101068089(wnt4)
LCO: 104923622(wnt4) 104932544
NCC: 104941051 104953830(wnt4)
MZE: 101473265(wnt4) 101479331
ONL: 100691883(wnt4) 100712297
OLA: 100301590(wnt4) 100301591(wnt4b)
XMA: 102232798(wnt4) 102236316
XCO: 114136002(wnt4) 114139694
PRET: 103465422(wnt4) 103477994
CVG: 107082204 107085099(wnt4)
NFU: 107374130(wnt4) 107379462
KMR: 108235425 108248640(wnt4)
ALIM: 106528517(wnt4) 106529149
AOCE: 111573832(wnt4) 111585705
CSEM: 103386287(wnt4) 103388020
POV: 109629351(wnt4) 109643472
LCF: 108877528(wnt4) 108880750
SDU: 111221581(wnt4) 111230085
SLAL: 111668597(wnt4) 111669912
HCQ: 109515380 109521622(wnt4)
BPEC: 110163101 110165764(wnt4)
MALB: 109966188 109971989(wnt4)
ELS: 105025459(wnt4) 105029960
LCM: 102358331(WNT4) 102366334
CMK: 103181434(wnt4)
RTP: 109914385
BFO: 118430603
CIN: 613215(wnt-a) 778721
APLC: 110984610
SKO: 100329013(Wnt4)
AME: 552374
BIM: 100743798
BTER: 100652118
CCAL: 108628454
OBB: 114872355
SOC: 105193451
MPHA: 105840148
AEC: 105151550
ACEP: 105619381
PBAR: 105430252
VEM: 105565123
HST: 105188249
DQU: 106748334
CFO: 105259399
LHU: 105668529
PGC: 109854335
OBO: 105286998
PCF: 106790923
NVI: 100122861
CSOL: 105362518
MDL: 103579666
TCA: 661650(WntA)
DPA: 109537233
NVL: 108558478
BMOR: 101735411
BMAN: 114243804
PMAC: 106716318
PRAP: 110995545
HAW: 110381010
TNL: 113499194
PXY: 105384815
API: 100164094
DNX: 107168857
BTAB: 109042201
CLEC: 106671088
ZNE: 110832362
TUT: 107361270
PTEP: 107444171
CEL: CELE_F38E1.7(mom-2) CELE_K10B4.6(cwn-1)
CBR: CBG06978(Cbr-cwn-1) CBG11282(Cbr-mom-2)
PCAN: 112557635
CRG: 105343129
MYI: 110451002
OBI: 106874406
SHX: MS3_03642
EGL: EGR_03061
PDAM: 113684198
SPIS: 111338419
DGT: 114518043
HMG: 100207084(hywnt16)
AQU: 100641115(Wnt)
 » show all
Reference
  Authors
Bernardi H, Gay S, Fedon Y, Vernus B, Bonnieu A, Bacou F
  Title
Wnt4 activates the canonical beta-catenin pathway and regulates negatively myostatin: functional implication in myogenesis.
  Journal
Am J Physiol Cell Physiol 300:C1122-38 (2011)
DOI:10.1152/ajpcell.00214.2010
Reference
  Authors
Saulnier DM, Ghanbari H, Brandli AW
  Title
Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.
  Journal
Dev Biol 248:13-28 (2002)
DOI:10.1006/dbio.2002.0712
  Sequence
[xla:397706]
Reference
  Authors
Jordan BK, Mohammed M, Ching ST, Delot E, Chen XN, Dewing P, Swain A, Rao PN, Elejalde BR, Vilain E
  Title
Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.
  Journal
Am J Hum Genet 68:1102-9 (2001)
DOI:10.1086/320125
  Sequence
[hsa:54361]
LinkDB

KEGG   ORTHOLOGY: K00444
Entry
K00444                      KO                                     

Name
WNT5
Definition
wingless-type MMTV integration site family, member 5
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00485  Robinow syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   04390 Hippo signaling pathway
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   04150 mTOR signaling pathway
    K00444  WNT5; wingless-type MMTV integration site family, member 5
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00444  WNT5; wingless-type MMTV integration site family, member 5
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00444  WNT5; wingless-type MMTV integration site family, member 5
  09158 Development and regeneration
   04360 Axon guidance
    K00444  WNT5; wingless-type MMTV integration site family, member 5
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   05205 Proteoglycans in cancer
    K00444  WNT5; wingless-type MMTV integration site family, member 5
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   05226 Gastric cancer
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   05217 Basal cell carcinoma
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   05224 Breast cancer
    K00444  WNT5; wingless-type MMTV integration site family, member 5
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00444  WNT5; wingless-type MMTV integration site family, member 5
   05022 Pathways of neurodegeneration - multiple diseases
    K00444  WNT5; wingless-type MMTV integration site family, member 5
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00444  WNT5; wingless-type MMTV integration site family, member 5
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00444  WNT5; wingless-type MMTV integration site family, member 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00444  WNT5; wingless-type MMTV integration site family, member 5
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00444  WNT5; wingless-type MMTV integration site family, member 5
Genes
HSA: 7474(WNT5A) 81029(WNT5B)
PTR: 460458(WNT5A) 467191(WNT5B)
PPS: 100975676(WNT5B) 100990957(WNT5A)
GGO: 101147792(WNT5A) 101151982(WNT5B)
PON: 100174132(WNT5B) 100447525(WNT5A)
NLE: 100596686(WNT5B) 100602014(WNT5A)
MCC: 705692(WNT5A) 721685(WNT5B)
MCF: 102129552(WNT5B) 102146380(WNT5A)
CSAB: 103218369(WNT5B) 103227777(WNT5A)
RRO: 104662531(WNT5B) 104676516(WNT5A)
RBB: 108522823(WNT5B) 108543619(WNT5A)
CJC: 100401066(WNT5A) 100405273(WNT5B)
SBQ: 101038250(WNT5B) 101040063(WNT5A)
MMU: 22418(Wnt5a) 22419(Wnt5b)
MCAL: 110295760(Wnt5b) 110309360(Wnt5a)
MPAH: 110316538(Wnt5b) 110325571(Wnt5a)
RNO: 282582(Wnt5b) 64566(Wnt5a)
MUN: 110560692(Wnt5a) 110562132(Wnt5b)
CGE: 100753017(Wnt5b) 100753089(Wnt5a)
NGI: 103739374(Wnt5b) 103749032(Wnt5a)
HGL: 101696315(Wnt5b) 101711272(Wnt5a)
CCAN: 109683366(Wnt5a) 109683371(Wnt5b)
OCU: 100009381(WNT5A) 100349579(WNT5B)
TUP: 102467720(WNT5B) 102489573(WNT5A)
CFA: 484721(WNT5A) 486756(WNT5B)
VVP: 112909974(WNT5A) 112917420(WNT5B)
AML: 100473854(WNT5B) 100484068(WNT5A)
UMR: 103675062(WNT5A) 103675761(WNT5B)
UAH: 113256990(WNT5A) 113258043(WNT5B)
ORO: 101364119(WNT5B) 101378764(WNT5A)
FCA: 101080694(WNT5A) 101085809(WNT5B)
PTG: 102958778(WNT5B) 102965201(WNT5A)
PPAD: 109276247(WNT5B) 109279118(WNT5A)
AJU: 106965408(WNT5B) 106967018(WNT5A)
BTA: 508008(WNT5B) 530005(WNT5A)
BOM: 102269211(WNT5A) 102276467(WNT5B)
BIU: 109559776(WNT5B) 109576252(WNT5A)
BBUB: 102403744(WNT5A) 102414969(WNT5B)
CHX: 102170921(WNT5A) 102176310(WNT5B)
OAS: 101109745(WNT5A) 101121415(WNT5B)
SSC: 100516268(WNT5B) 100627056(WNT5A)
CFR: 102505627(WNT5A) 102515730(WNT5B)
CDK: 105089783(WNT5A) 105102929(WNT5B)
BACU: 103001360 103020226(WNT5B)
LVE: 103070287(WNT5A) 103086235(WNT5B)
OOR: 101278965(WNT5A) 101289426(WNT5B)
DLE: 111174269(WNT5A) 111176602(WNT5B)
PCAD: 102984556(WNT5A)
ECB: 100056017(WNT5B) 100059157(WNT5A)
EPZ: 103543266 103555816(WNT5B) 103565849(WNT5A)
EAI: 106824632(WNT5B) 106848670(WNT5A)
MYB: 102240132(WNT5A) 102241642(WNT5B)
MYD: 102755774(WNT5B) 102771010(WNT5A)
MNA: 107530635(WNT5A) 107546464(WNT5B)
HAI: 109388973(WNT5B) 109389090(WNT5A)
DRO: 112300408(WNT5B) 112301279(WNT5A)
PALE: 102881682(WNT5B) 102890342(WNT5A)
RAY: 107500582(WNT5B) 107503411(WNT5A)
MJV: 108397016(WNT5B) 108403168(WNT5A)
LAV: 100658849(WNT5A) 100664544(WNT5B)
MDO: 100012859(WNT5A) 100021212(WNT5B)
SHR: 100917926(WNT5A) 100924415(WNT5B)
PCW: 110197037(WNT5A) 110218688(WNT5B)
OAA: 100085809(WNT5B) 100088897(WNT5A)
GGA: 395703(WNT5A) 418154(WNT5B)
MGP: 100544120(WNT5B) 100546517(WNT5A)
CJO: 107315234(WNT5B) 107320001(WNT5A)
NMEL: 110395425(WNT5B) 110404902(WNT5A)
APLA: 101792356(WNT5B) 101802371(WNT5A)
ACYG: 106030939(WNT5B) 106040536(WNT5A)
TGU: 100219241(WNT5A) 100232701(WNT5B)
LSR: 110472531(WNT5A) 110472984(WNT5B)
SCAN: 103816996(WNT5A) 103820459(WNT5B)
GFR: 102035335(WNT5B) 102037267(WNT5A)
FAB: 101812087(WNT5B) 101821076(WNT5A)
PHI: 102102367(WNT5A) 102105513(WNT5B)
PMAJ: 107205138(WNT5B) 107210457(WNT5A)
CCAE: 111927965(WNT5B) 111935118(WNT5A)
CCW: 104683261(WNT5A) 104692240(WNT5B)
ETL: 114057953(WNT5A) 114069222(WNT5B)
FPG: 101915287(WNT5B) 101918836(WNT5A)
FCH: 102048667(WNT5B) 102054189(WNT5A)
CLV: 102089531(WNT5A) 102095873(WNT5B)
EGZ: 104126727(WNT5A) 104134402(WNT5B)
NNI: 104015319(WNT5A) 104020249(WNT5B)
ACUN: 113484834(WNT5A) 113491596(WNT5B)
PADL: 103924369(WNT5B) 103925486(WNT5A)
ASN: 102373200(WNT5A) 102382716(WNT5B)
AMJ: 102568211(WNT5B) 102574844(WNT5A)
PSS: 102449222(WNT5A) 102462233(WNT5B)
CMY: 102932991(WNT5A) 102939545(WNT5B)
CPIC: 101931085(WNT5B) 101953903(WNT5A)
ACS: 100555653(wnt5a) 100562948(wnt5b)
PVT: 110076695(WNT5B) 110082405
PBI: 103052931(WNT5B) 103063567(WNT5A)
PMUR: 107292714(WNT5A) 107294505(WNT5B)
TSR: 106550539(WNT5B) 106553936(WNT5A)
PMUA: 114591691(WNT5A) 114604941(WNT5B)
GJA: 107109428(WNT5A) 107120233(WNT5B)
XLA: 108704022 108704582 378689(wnt5a.S) 379842(wnt5b.S)
XTR: 101734372(wnt5a) 448452(wnt5b)
NPR: 108786048(WNT5A) 108804614(WNT5B)
DRE: 30105(wnt5b) 568191(wnt5a)
IPU: 108265992(wnt5a) 108279752(wnt5b)
PHYP: 113531892 113533531(wnt5a)
AMEX: 103026771 103037231(wnt5a)
TRU: 101067574 101075293(wnt5a)
LCO: 104924622(wnt5b) 104931731(wnt5a)
NCC: 104946406(wnt5a)
OLA: 100049184(wnt5b) 101160069
NFU: 107385014 107391003(wnt5a)
CSEM: 103382784(wnt5b) 103384668
LCF: 108877892 108894955(wnt5b)
SFM: 108920949(wnt5b) 108925614(wnt5a)
PKI: 111843135(wnt5b) 111848787
LCM: 102352271(WNT5B) 102366294(WNT5A)
CMK: 103176770(wnt5a) 103181804(wnt5b)
RTP: 109917715(wnt5b) 109932604
BFO: 118415326
CIN: 445761(wnt5)
APLC: 110974216
SKO: 100313542(Wnt5)
DME: Dmel_CG6407(Wnt5)
DER: 6550249
DSE: 6614874
DSI: Dsimw501_GD15629(Dsim_GD15629)
DPE: 6603244
DWI: 6640063
DAZ: 108615488
DNV: 108652936
DHE: 111600139
DVI: 6625997
MDE: 101892275
AAG: 5579522
AME: 414037
BIM: 100747561
BTER: 100650651
CCAL: 108631659
OBB: 114876139
SOC: 105193557
MPHA: 105833071
AEC: 105151721
ACEP: 105618833
PBAR: 105424527
VEM: 105566951
HST: 105182188
DQU: 106747834
CFO: 105256941
LHU: 105667940
PGC: 109860310
OBO: 105284555
PCF: 106789889
NVI: 100120030
CSOL: 105368807
TCA: 663552(Wnt5)
DPA: 109536340
ATD: 109595177
NVL: 108560493
BMOR: 101739064
BMAN: 114243789
PMAC: 106721095
PRAP: 110993384
HAW: 110378041
TNL: 113496093
BTAB: 109036793
CLEC: 106671110
ZNE: 110837886
DPX: DAPPUDRAFT_64675(WNT5)
PVM: 113806005
DPTE: 113789880
CSCU: 111618001
TSP: Tsp_02528
MYI: 110441941
OBI: 106870281 106883934(Wnt5)
SHX: MS3_06684
EGL: EGR_00103
EPA: 110242534
ADF: 107339929
AMIL: 114967395
DGT: 114521467
HMG: 100202930(hywnt5a)
 » show all
Reference
  Authors
Yamaguchi TP, Bradley A, McMahon AP, Jones S
  Title
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo.
  Journal
Development 126:1211-23 (1999)
  Sequence
[mmu:22418]
Reference
PMID:8288227
  Authors
Clark CC, Cohen I, Eichstetter I, Cannizzaro LA, McPherson JD, Wasmuth JJ, Iozzo RV
  Title
Molecular cloning of the human proto-oncogene Wnt-5A and mapping of the gene (WNT5A) to chromosome 3p14-p21.
  Journal
Genomics 18:249-60 (1993)
DOI:10.1006/geno.1993.1463
  Sequence
[hsa:7474]
Reference
  Authors
Saitoh T, Katoh M
  Title
Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region.
  Journal
Int J Oncol 19:347-51 (2001)
DOI:10.3892/ijo.19.2.347
  Sequence
[hsa:81029]
LinkDB

KEGG   ORTHOLOGY: K00445
Entry
K00445                      KO                                     

Name
WNT6
Definition
wingless-type MMTV integration site family, member 6
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04390 Hippo signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   04150 mTOR signaling pathway
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05205 Proteoglycans in cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05226 Gastric cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05217 Basal cell carcinoma
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05224 Breast cancer
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00445  WNT6; wingless-type MMTV integration site family, member 6
   05022 Pathways of neurodegeneration - multiple diseases
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00445  WNT6; wingless-type MMTV integration site family, member 6
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00445  WNT6; wingless-type MMTV integration site family, member 6
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00445  WNT6; wingless-type MMTV integration site family, member 6
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00445  WNT6; wingless-type MMTV integration site family, member 6
Genes
HSA: 7475(WNT6)
PTR: 742467(WNT6)
PPS: 100987794(WNT6)
GGO: 101132496(WNT6)
PON: 100440643(WNT6)
NLE: 100606818(WNT6)
MCC: 700573(WNT6)
MCF: 102132660(WNT6)
CSAB: 103217884(WNT6)
RRO: 104660036(WNT6)
RBB: 108518481(WNT6)
CJC: 100394855(WNT6)
SBQ: 101028364(WNT6)
MMU: 22420(Wnt6)
MCAL: 110299810(Wnt6)
MPAH: 110321884(Wnt6)
RNO: 316526(Wnt6)
MUN: 110566399(Wnt6)
CGE: 100751289(Wnt6)
NGI: 103727729(Wnt6)
HGL: 101698823(Wnt6)
CCAN: 109693790(Wnt6)
OCU: 100348986(WNT6)
TUP: 102483667(WNT6)
CFA: 488527(WNT6)
VVP: 112922542(WNT6)
AML: 100467896(WNT6)
UAH: 113250444(WNT6)
ORO: 101374890(WNT6)
ELK: 111145739
FCA: 101099392(WNT6)
PPAD: 109265051(WNT6)
AJU: 106970073(WNT6)
BTA: 505075(WNT6)
BOM: 102286828(WNT6)
BIU: 109570782(WNT6)
BBUB: 102407032(WNT6)
CHX: 108637658(WNT6)
OAS: 101111785(WNT6)
SSC: 100622044(WNT6)
CFR: 102511574(WNT6)
CDK: 105096131(WNT6)
BACU: 102997453(WNT6)
LVE: 103079243(WNT6)
OOR: 101288015(WNT6)
DLE: 111172090(WNT6)
PCAD: 102993713(WNT6)
ECB: 100058824(WNT6)
EPZ: 103567913(WNT6)
EAI: 106838461(WNT6)
MYB: 102256374(WNT6)
MYD: 102757803(WNT6)
MNA: 107524769(WNT6)
HAI: 109380535(WNT6)
DRO: 112308052(WNT6)
PALE: 102882368(WNT6)
RAY: 107516780(WNT6)
MJV: 108390505(WNT6)
LAV: 100675069(WNT6)
TMU: 101341737
MDO: 100010861(WNT6)
SHR: 100933826(WNT6)
PCW: 110219493(WNT6)
OAA: 100089786(WNT6)
GGA: 395235(WNT6)
MGP: 100540128(WNT6)
CJO: 107317037(WNT6)
NMEL: 110400365(WNT6)
APLA: 101803438(WNT6)
ACYG: 106039313(WNT6)
TGU: 100230318(WNT6)
LSR: 110468403(WNT6)
SCAN: 103814356(WNT6)
GFR: 102035490(WNT6)
FAB: 101819686(WNT6)
PHI: 102100841(WNT6)
PMAJ: 107207801(WNT6)
CCAE: 111931742(WNT6) 111943653
CCW: 104693964(WNT6)
ETL: 114055668(WNT6)
FPG: 101921385(WNT6)
FCH: 102054753(WNT6)
CLV: 102085008(WNT6)
EGZ: 104132404(WNT6)
NNI: 104010067(WNT6)
ACUN: 113482396(WNT6)
PADL: 103917663(WNT6)
AAM: 106499139(WNT6)
ASN: 102377243(WNT6)
AMJ: 106737397(WNT6)
CPIC: 101949600(WNT6)
ACS: 100565609(wnt6)
PVT: 110078170(WNT6)
PBI: 103054454(WNT6)
PMUR: 107292513(WNT6)
TSR: 106540757(WNT6)
PMUA: 114603052(WNT6)
GJA: 107107564(WNT6)
XLA: 108701298(wnt6.L) 378676(wnt6.S)
XTR: 101733784(wnt6)
NPR: 108801546(WNT6)
DRE: 100332722(wnt6a) 561831(wnt6b)
IPU: 108266110(wnt6) 108273177
PHYP: 113523750(wnt6) 113538450
AMEX: 103038704 103041984(wnt6)
EEE: 113574053 113591172(wnt6)
TRU: 101062888(wnt6)
LCO: 104919603(wnt6)
NCC: 104943745(wnt6)
MZE: 101474169(wnt6)
ONL: 100695021(wnt6)
OLA: 101174712(wnt6)
XMA: 102234174(wnt6)
XCO: 114148282(wnt6)
PRET: 103460530(wnt6)
CVG: 107092662(wnt6)
NFU: 107390192(wnt6)
KMR: 108238486(wnt6)
ALIM: 106523158(wnt6)
AOCE: 111580967(wnt6)
CSEM: 103392496
POV: 109631098(wnt6)
LCF: 108902815(wnt6)
SDU: 111218508(wnt6)
SLAL: 111668743(wnt6)
HCQ: 109522420(wnt6)
BPEC: 110156189(wnt6)
MALB: 109964395(wnt6)
SASA: 106581837(wnt6) 106586152
SALP: 111972696 111974089(wnt6)
ELS: 105029531(wnt6)
SFM: 108927964(wnt6)
PKI: 111848415(wnt6) 111858301
LCM: 102350297 102352652(WNT6)
BFO: 118405738
CIN: 778723
SPU: 585147
APLC: 110984744
SKO: 100313763(Wnt6)
DME: Dmel_CG4969(Wnt6)
DER: 6542672
DSE: 6611515
DSI: Dsimw501_GD23460(Dsim_wg)
DAN: 6498657
DSR: 110182670
DPE: 6589315
DMN: 108162806
DWI: 6644099
DAZ: 108611686
DNV: 108658171
DHE: 111602345
DVI: 6628631
MDE: 101898284
LCQ: 111677056
AAG: 5564830
AME: 413501
BIM: 100745430
BTER: 100647833
CCAL: 108622250
OBB: 114871802
SOC: 105200052
MPHA: 105838834
AEC: 105150855
ACEP: 105618731
PBAR: 105429522
VEM: 105566204
HST: 105189290
DQU: 106746483
CFO: 105258968
LHU: 105676116
PGC: 109859095
OBO: 105285325
PCF: 106792536
NVI: 100119613
CSOL: 105367707
TCA: 656429(Wnt6)
DPA: 109545719
NVL: 108563654
BMOR: 101741216
BMAN: 114248774
PMAC: 106714253
PRAP: 110994201
HAW: 110371053
TNL: 113501221
PXY: 105397939
BTAB: 109044640
ZNE: 110828845
FCD: 110849830
DPX: DAPPUDRAFT_290641(WNT6)
DPTE: 113795868
PTEP: 107438387
PCAN: 112559562
CRG: 105348241
MYI: 110462024
OBI: 106878314
LAK: 106180551
EPA: 110250756
ADF: 107333377
AMIL: 114957169
PDAM: 113671496
SPIS: 111330934
DGT: 114517724
 » show all
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
  Journal
Biochem Biophys Res Commun 283:798-805 (2001)
DOI:10.1006/bbrc.2001.4855
  Sequence
[hsa:7475]
Reference
  Authors
Yuan G, Regel I, Lian F, Friedrich T, Hitkova I, Hofheinz RD, Strobel P, Langer R, Keller G, Rocken C, Zimmermann W, Schmid RM, Ebert MP, Burgermeister E
  Title
WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells.
  Journal
Oncogene 32:375-87 (2013)
DOI:10.1038/onc.2012.40
  Sequence
[hsa:7475]
LinkDB

KEGG   ORTHOLOGY: K00572
Entry
K00572                      KO                                     

Name
WNT7
Definition
wingless-type MMTV integration site family, member 7
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00846  Fuhrmann syndrome
H00847  Al-Awadi/Raas-Rothschild syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   04390 Hippo signaling pathway
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   04150 mTOR signaling pathway
    K00572  WNT7; wingless-type MMTV integration site family, member 7
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00572  WNT7; wingless-type MMTV integration site family, member 7
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00572  WNT7; wingless-type MMTV integration site family, member 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   05205 Proteoglycans in cancer
    K00572  WNT7; wingless-type MMTV integration site family, member 7
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   05226 Gastric cancer
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   05217 Basal cell carcinoma
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   05224 Breast cancer
    K00572  WNT7; wingless-type MMTV integration site family, member 7
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00572  WNT7; wingless-type MMTV integration site family, member 7
   05022 Pathways of neurodegeneration - multiple diseases
    K00572  WNT7; wingless-type MMTV integration site family, member 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00572  WNT7; wingless-type MMTV integration site family, member 7
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00572  WNT7; wingless-type MMTV integration site family, member 7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00572  WNT7; wingless-type MMTV integration site family, member 7
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00572  WNT7; wingless-type MMTV integration site family, member 7
Genes
HSA: 7476(WNT7A) 7477(WNT7B)
PTR: 104003805(WNT7B) 749914(WNT7A)
PPS: 100977315(WNT7B) 100995012(WNT7A)
GGO: 101146237(WNT7A) 115931954(WNT7B)
PON: 100441147(WNT7A) 100451196(WNT7B)
NLE: 100579580(WNT7B) 100593900(WNT7A)
MCC: 693419(WNT7A) 713864(WNT7B)
MCF: 102135636(WNT7B) 102137321(WNT7A)
CSAB: 103223483(WNT7B) 103228043(WNT7A)
RRO: 104676099(WNT7B) 104679020(WNT7A)
RBB: 108514489(WNT7B) 108544845(WNT7A)
CJC: 100387909(WNT7A) 100414221(WNT7B)
SBQ: 101027644(WNT7A)
MMU: 22421(Wnt7a) 22422(Wnt7b)
MCAL: 110296669(Wnt7a) 110310689(Wnt7b)
MPAH: 110316305(Wnt7a) 110335001(Wnt7b)
RNO: 114850(Wnt7a) 315196(Wnt7b)
MUN: 110545047(Wnt7b) 110549843(Wnt7a)
CGE: 100755799(Wnt7b) 100772978(Wnt7a)
NGI: 103730373(Wnt7a) 103743417(Wnt7b)
HGL: 101725735(Wnt7a) 101726616(Wnt7b)
CCAN: 109679085 109699751(Wnt7b)
OCU: 100355697(WNT7A) 103347432
TUP: 102484353(WNT7A) 102500004(WNT7B)
CFA: 481206(WNT7B) 607180(WNT7A)
VVP: 112914456(WNT7A) 112935842(WNT7B)
AML: 100474982(WNT7B) 100475153(WNT7A)
UMR: 103669629(WNT7A) 103674134(WNT7B)
UAH: 113241648(WNT7B) 113257229(WNT7A)
ORO: 101381717(WNT7A) 101386348(WNT7B)
FCA: 101083664(WNT7A) 101095592(WNT7B)
PTG: 102972888(WNT7A)
PPAD: 109257500(WNT7A) 109265719(WNT7B)
AJU: 106978815(WNT7A) 113602684(WNT7B)
BTA: 100337066(WNT7B) 533782(WNT7A)
BIU: 109558644(WNT7B) 109576501(WNT7A)
BBUB: 102399122(WNT7A) 102401643(WNT7B)
CHX: 102171665(WNT7A) 102176768(WNT7B)
OAS: 101109531(WNT7B) 114109341(WNT7A)
SSC: 100153445(WNT7A) 100626947(WNT7B)
CFR: 102506800(WNT7A) 102519277(WNT7B)
CDK: 105091978(WNT7B) 105093166(WNT7A)
BACU: 103004744(WNT7B) 103016619
LVE: 103068582(WNT7A) 103083305(WNT7B)
OOR: 101278865(WNT7A) 101282844(WNT7B)
DLE: 111168811(WNT7A) 111186418(WNT7B)
PCAD: 102985991(WNT7B) 114484267(WNT7A)
ECB: 100053027(WNT7B) 100055450(WNT7A) 111768287
EPZ: 103556791(WNT7A) 103558099(WNT7B)
EAI: 106829376(WNT7A) 106845973(WNT7B)
MYB: 102249626(WNT7A) 102257706(WNT7B)
MYD: 102758002
MNA: 107534839(WNT7B) 107537987(WNT7A)
HAI: 109387605(WNT7B) 109390460(WNT7A)
DRO: 112320683(WNT7A) 112322077(WNT7B)
PALE: 102888597(WNT7A) 102898026(WNT7B)
RAY: 107502411(WNT7A) 107505517(WNT7B)
MJV: 108404182(WNT7A) 108406731(WNT7B)
LAV: 100660629(WNT7B) 100675463(WNT7A)
MDO: 100014091(WNT7B) 100028905(WNT7A)
SHR: 100925362(WNT7B) 100931119(WNT7A)
PCW: 110201658(WNT7B) 110204974(WNT7A)
OAA: 100075994(WNT7A) 100088910 100093588(WNT7B)
GGA: 374168(WNT7A) 427937(WNT7B)
MGP: 100542203(WNT7B) 100542958(WNT7A)
CJO: 107317577(WNT7B) 107319707(WNT7A)
NMEL: 110397148(WNT7B) 110404875(WNT7A)
APLA: 101792761(WNT7A) 101805245(WNT7B)
ACYG: 106038211(WNT7B) 106040033(WNT7A)
TGU: 100220226(WNT7B) 100220584(WNT7A)
LSR: 110470371(WNT7B) 110479430(WNT7A)
SCAN: 103816927(WNT7A) 103820439(WNT7B)
GFR: 102043987(WNT7A) 102044794(WNT7B)
FAB: 101813299(WNT7A) 101816884(WNT7B)
PHI: 102113507(WNT7B) 102113528(WNT7A)
PMAJ: 107204452(WNT7B) 107210469(WNT7A)
CCAE: 111923341(WNT7B) 111935250(WNT7A)
CCW: 104695759(WNT7A) 104696093(WNT7B)
ETL: 114067661(WNT7A) 114068280
FPG: 101913212(WNT7A) 101919373(WNT7B)
FCH: 102050340(WNT7B) 102056992(WNT7A)
CLV: 102084979(WNT7B) 102088082
EGZ: 104124300(WNT7A) 104135171(WNT7B)
NNI: 104012662(WNT7B) 104022169(WNT7A)
ACUN: 113475861(WNT7B) 113484979(WNT7A)
PADL: 103916628(WNT7B) 103924109(WNT7A)
AAM: 106488582(WNT7A) 106488789(WNT7B)
AMJ: 102568312(WNT7B) 102575772(WNT7A)
PSS: 102450567(WNT7B) 102452569(WNT7A)
CMY: 102942821(WNT7B) 102945035(WNT7A)
CPIC: 101934994(WNT7B) 101939685(WNT7A)
ACS: 100553258(wnt7a) 100567981(wnt7b)
PVT: 110075003(WNT7B) 110081630(WNT7A)
PBI: 103052813(WNT7A) 103059073(WNT7B)
PMUR: 107285548 107287015(WNT7B)
PMUA: 114591664(WNT7A) 114596772(WNT7B)
GJA: 107114761(WNT7B) 107118817(WNT7A)
XTR: 100145124(wnt7b) 100490426(wnt7c) 105947033(wnt7a)
DRE: 100148840(wnt7bb) 563427(wnt7ba) 565714(wnt7aa) 568110
AMEX: 103026929 103027182(wnt7a) 103028473(wnt7b) 103046044
NCC: 104955515 104966327(wnt7b) 104966749(wnt7a)
CMK: 103179433(wnt7b) 103185034(wnt7a)
CIN: 778938
SPU: 581981
SKO: 100313764(Wnt7) 100329104
DER: 6542264
DSI: Dsimw501_GD10659(Dsim_GD10659)
DSR: 110189137
DPE: 6592209
DMN: 108160637
DWI: 6640767
DAZ: 108615928
DNV: 108653824
DHE: 111604601
DVI: 6636452
MDE: 101889017
LCQ: 111688655
AME: 411919
BIM: 100741405
BTER: 100646705
OBB: 114882874
SOC: 105193029
MPHA: 105833587
ACEP: 105618028
PBAR: 105432993
VEM: 105563393
HST: 105181239
DQU: 106741954
CFO: 105259313
LHU: 105673358
PGC: 109853360
OBO: 105283919
PCF: 106791180
NVI: 100122745
CSOL: 105362923
MDL: 103580558
TCA: 661936(Wnt7)
DPA: 109536345
ATD: 109597141
NVL: 108562837
BMOR: 101740841
BMAN: 114240915
PMAC: 106713271
PRAP: 110995122
HAW: 110382331
TNL: 113506522
API: 100168810
DNX: 107166553
AGS: 114124781
RMD: 113559834
BTAB: 109041803
CLEC: 106671019
ZNE: 110840788
FCD: 110845687
DPX: DAPPUDRAFT_64642(WNT7)
DPTE: 113789916
BMY: Bm1_12430
PCAN: 112571885
CRG: 105337729
MYI: 110441939
OBI: 106876541 106878439(Wnt7)
LAK: 106162452
HMG: 100198339(hywnt9/10b) 100214773(hywnt9/10c)
AQU: 100616534(WntB)
 » show all
Reference
PMID:9161407
  Authors
Bui TD, Lako M, Lejeune S, Curtis AR, Strachan T, Lindsay S, Harris AL
  Title
Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25.
  Journal
Gene 189:25-9 (1997)
DOI:10.1016/S0378-1119(96)00808-6
  Sequence
[hsa:7476]
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
Molecular cloning and characterization of human WNT7B.
  Journal
Int J Oncol 19:779-83 (2001)
DOI:10.3892/ijo.19.4.779
  Sequence
[hsa:7477]
Reference
PMID:9790192
  Authors
Parr BA, McMahon AP
  Title
Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a.
  Journal
Nature 395:707-10 (1998)
DOI:10.1038/27221
  Sequence
[mmu:22421]
LinkDB

KEGG   ORTHOLOGY: K00714
Entry
K00714                      KO                                     

Name
WNT8
Definition
wingless-type MMTV integration site family, member 8
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   04390 Hippo signaling pathway
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   04150 mTOR signaling pathway
    K00714  WNT8; wingless-type MMTV integration site family, member 8
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K00714  WNT8; wingless-type MMTV integration site family, member 8
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K00714  WNT8; wingless-type MMTV integration site family, member 8
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   05205 Proteoglycans in cancer
    K00714  WNT8; wingless-type MMTV integration site family, member 8
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   05226 Gastric cancer
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   05217 Basal cell carcinoma
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   05224 Breast cancer
    K00714  WNT8; wingless-type MMTV integration site family, member 8
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00714  WNT8; wingless-type MMTV integration site family, member 8
   05022 Pathways of neurodegeneration - multiple diseases
    K00714  WNT8; wingless-type MMTV integration site family, member 8
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K00714  WNT8; wingless-type MMTV integration site family, member 8
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K00714  WNT8; wingless-type MMTV integration site family, member 8
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K00714  WNT8; wingless-type MMTV integration site family, member 8
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K00714  WNT8; wingless-type MMTV integration site family, member 8
Genes
HSA: 7478(WNT8A) 7479(WNT8B)
PTR: 466182(WNT8B) 471645(WNT8A)
PPS: 100969578(WNT8B) 100993563(WNT8A)
GGO: 101140197(WNT8B) 101148055(WNT8A)
PON: 100448766(WNT8A) 100450268(WNT8B)
NLE: 100586052(WNT8A) 100603238(WNT8B)
MCC: 710242(WNT8B) 713764(WNT8A)
MCF: 102120527(WNT8A) 102121324(WNT8B)
CSAB: 103216388(WNT8B) 103244620(WNT8A)
RRO: 104656476(WNT8B) 104681717(WNT8A)
RBB: 108527856(WNT8A) 108535264(WNT8B)
CJC: 100402422(WNT8A) 100414921(WNT8B)
SBQ: 101037830(WNT8A) 101041057(WNT8B)
MMU: 20890(Wnt8a) 22423(Wnt8b)
MCAL: 110285093(Wnt8a) 110285759(Wnt8b)
MPAH: 110330357(Wnt8b) 110333515(Wnt8a)
RNO: 291678(Wnt8a) 293990(Wnt8b)
MUN: 110551101(Wnt8a) 110556815(Wnt8b)
CGE: 100752907(Wnt8a) 100775075(Wnt8b)
NGI: 103735176(Wnt8a) 103743982(Wnt8b)
HGL: 101711747(Wnt8a) 101715077(Wnt8b)
CCAN: 109698141(Wnt8b) 109700179(Wnt8a)
OCU: 100342870(WNT8A) 100357933(WNT8B)
TUP: 102468229(WNT8B) 102490209(WNT8A)
CFA: 100855884(WNT8A) 486841(WNT8B)
VVP: 112914893(WNT8B) 112921902(WNT8A)
AML: 100466672(WNT8B) 100481684(WNT8A)
UMR: 103658927(WNT8B) 103663793(WNT8A)
UAH: 113251621(WNT8B) 113261780(WNT8A)
ORO: 101365801(WNT8B) 101370196(WNT8A)
FCA: 101089489(WNT8A) 101096357(WNT8B)
PTG: 102956179(WNT8B) 102966525(WNT8A)
PPAD: 109252095(WNT8A) 109272682(WNT8B)
AJU: 106966936(WNT8B) 106968544(WNT8A)
BTA: 538720(WNT8B) 540199(WNT8A)
BOM: 102285045(WNT8A) 102285959(WNT8B)
BIU: 109561268(WNT8A) 109578990(WNT8B)
BBUB: 102389510(WNT8A) 102413228(WNT8B)
CHX: 102176193(WNT8B) 102184053(WNT8A)
OAS: 101108044(WNT8A) 101121814(WNT8B)
SSC: 100513655(WNT8B) 100739710(WNT8A)
CFR: 102507167(WNT8B) 102514705(WNT8A)
CDK: 105084321(WNT8B) 105090590(WNT8A)
BACU: 103004198(WNT8A) 103014029(WNT8B)
LVE: 103086715(WNT8B) 103091305(WNT8A)
OOR: 101278440(WNT8A) 101284317(WNT8B)
DLE: 111172662(WNT8B) 111182565(WNT8A)
PCAD: 102975016(WNT8B) 102982375(WNT8A)
ECB: 100070360(WNT8B) 100072609(WNT8A)
EPZ: 103562517(WNT8B) 103563555(WNT8A)
EAI: 106839204(WNT8A) 106846753(WNT8B)
MYB: 102255244(WNT8A) 102260194(WNT8B)
MYD: 102758435(WNT8B) 102763548(WNT8A)
MNA: 107530103(WNT8A) 107542524(WNT8B)
HAI: 109379609(WNT8B) 109392505(WNT8A)
DRO: 112300327(WNT8B) 112318177(WNT8A)
PALE: 102878209(WNT8B) 102896480(WNT8A)
RAY: 107499773(WNT8B) 107518710(WNT8A)
MJV: 108409584(WNT8B) 108410319(WNT8A)
LAV: 100665788(WNT8B) 100668409(WNT8A)
MDO: 100024816(WNT8A) 100027787(WNT8B)
SHR: 100923381(WNT8A) 100934290(WNT8B)
PCW: 110213976(WNT8B) 110220834(WNT8A)
OAA: 100079874(WNT8B) 100085370(WNT8A)
GGA: 396543(WNT8A) 428953(WNT8B)
MGP: 100539004(WNT8A) 100545216(WNT8B)
CJO: 107315787(WNT8B) 107320095(WNT8A)
NMEL: 110399767(WNT8B) 110405162(WNT8A)
APLA: 101796899(WNT8B) 101797449(WNT8A)
ACYG: 106029610(WNT8B) 106032798(WNT8A)
TGU: 100219521(WNT8A) 100230877(WNT8B)
LSR: 110480021(WNT8B) 110482746(WNT8A)
SCAN: 103813966(WNT8B) 103817277(WNT8A)
GFR: 102039167(WNT8B) 102042115(WNT8A)
FAB: 101812440(WNT8B) 101817235(WNT8A)
PHI: 102105800(WNT8A) 102111196(WNT8B)
PMAJ: 107206563(WNT8B) 107210897(WNT8A)
CCAE: 111930909(WNT8B) 111935572(WNT8A)
CCW: 104689602(WNT8A) 104696979(WNT8B)
ETL: 114054724(WNT8B) 114065213(WNT8A)
FPG: 101913195(WNT8B) 101922564(WNT8A)
FCH: 102050520(WNT8B) 102057135(WNT8A)
CLV: 102087818(WNT8A) 102096116(WNT8B)
EGZ: 104128446(WNT8A) 104129128(WNT8B)
NNI: 104013446(WNT8B) 104018452(WNT8A)
ACUN: 113481529(WNT8B) 113485446(WNT8A)
PADL: 103915555(WNT8B) 103915763(WNT8A)
ASN: 102372347(WNT8B) 102378786(WNT8A)
AMJ: 102564241(WNT8A) 102576973(WNT8B)
PSS: 102454779(WNT8A)
CMY: 102931581(WNT8B) 102941464
CPIC: 101932342(WNT8A) 101951189(WNT8B)
ACS: 100558725(wnt8a) 100564473(wnt8b)
PVT: 110073498(WNT8A) 110077779(WNT8B)
PBI: 103048991(WNT8B) 103048995(WNT8A)
PMUR: 107289015(WNT8A) 107292979(WNT8B)
TSR: 106551034(WNT8B) 106553431(WNT8A)
PMUA: 114591307(WNT8A) 114597000(WNT8B)
GJA: 107112608(WNT8A) 107120805
XLA: 108696239 108713288 397970(wnt8a.L) 399098(wnt8b.S)
XTR: 100496786(wnt8b) 549962(wnt8a)
NPR: 108797406(WNT8A) 108800950(WNT8B)
DRE: 30122(wnt8a) 30144(wnt8b) 553976(wnt8-2)
TRU: 101073059 445897(wnt8)
LCM: 102347690(WNT8B) 102353855(WNT8A)
CMK: 103182768(wnt8b) 103183727(wnt8a)
BFO: 118411526
SPU: 397068(Wnt8)
APLC: 110980473
SKO: 100313765(Wnt8)
DME: Dmel_CG8458(wntD)
DER: 6553201
DSE: 6606552
DSI: Dsimw501_GD20509(Dsim_GD20509)
DAN: 6500178
DSR: 110186133
DPE: 6587352
DMN: 108157077
DWI: 6650873
DAZ: 108621606
DNV: 108659634
DHE: 111603244
DVI: 6632420
LCQ: 111690603
TCA: 660084(Wnt8/D)
NVL: 108569023
CLEC: 106673350
DPX: DAPPUDRAFT_347557(WNT8.2)
TUT: 107367025
DPTE: 113790795
PTEP: 107453612
PCAN: 112571743
CRG: 105317364
MYI: 110443211
OBI: 106872351
LAK: 106168008
DGT: 114527658
HMG: 100200795(hywnt8)
 » show all
Reference
  Authors
Saitoh T, Katoh M
  Title
Molecular cloning and characterization of human WNT8A.
  Journal
Int J Oncol 19:123-7 (2001)
DOI:10.3892/ijo.19.1.123
  Sequence
[hsa:7478]
Reference
PMID:9536085
  Authors
Lako M, Lindsay S, Bullen P, Wilson DI, Robson SC, Strachan T
  Title
A novel mammalian wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain.
  Journal
Hum Mol Genet 7:813-22 (1998)
DOI:10.1093/hmg/7.5.813
  Sequence
[hsa:7479]
LinkDB

KEGG   ORTHOLOGY: K01064
Entry
K01064                      KO                                     

Name
WNT9
Definition
wingless-type MMTV integration site family, member 9
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   04390 Hippo signaling pathway
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   04150 mTOR signaling pathway
    K01064  WNT9; wingless-type MMTV integration site family, member 9
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K01064  WNT9; wingless-type MMTV integration site family, member 9
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K01064  WNT9; wingless-type MMTV integration site family, member 9
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   05205 Proteoglycans in cancer
    K01064  WNT9; wingless-type MMTV integration site family, member 9
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   05226 Gastric cancer
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   05217 Basal cell carcinoma
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   05224 Breast cancer
    K01064  WNT9; wingless-type MMTV integration site family, member 9
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K01064  WNT9; wingless-type MMTV integration site family, member 9
   05022 Pathways of neurodegeneration - multiple diseases
    K01064  WNT9; wingless-type MMTV integration site family, member 9
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K01064  WNT9; wingless-type MMTV integration site family, member 9
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K01064  WNT9; wingless-type MMTV integration site family, member 9
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K01064  WNT9; wingless-type MMTV integration site family, member 9
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K01064  WNT9; wingless-type MMTV integration site family, member 9
Genes
HSA: 7483(WNT9A) 7484(WNT9B)
PTR: 468296(WNT9B) 469697(WNT9A)
PPS: 100986204(WNT9A) 100993261(WNT9B)
GGO: 101134101(WNT9B) 101147170(WNT9A)
PON: 100452135(WNT9A) 100462535(WNT9B)
NLE: 100602760(WNT9B) 100606502(WNT9A)
MCC: 696326(WNT9A) 716877(WNT9B)
MCF: 101867270(WNT9A) 102130297(WNT9B)
CSAB: 103229968(WNT9A) 103243254(WNT9B)
RRO: 104672033(WNT9A) 104682400(WNT9B)
RBB: 108529352(WNT9B) 108536803(WNT9A)
CJC: 100393646(WNT9B) 100397032(WNT9A)
SBQ: 104650180(WNT9B)
MMU: 216795(Wnt9a) 22412(Wnt9b)
MCAL: 110305968(Wnt9b) 110306039(Wnt9a)
MPAH: 110331284(Wnt9a) 110332442(Wnt9b)
RNO: 287357(Wnt9a) 303586(Wnt9b)
MUN: 110545623(Wnt9b) 110566850(Wnt9a)
CGE: 100764466(Wnt9a) 100766088(Wnt9b)
NGI: 103724773(Wnt9b) 103740409(Wnt9a)
HGL: 101705646(Wnt9b) 101715480(Wnt9a)
CCAN: 109700763(Wnt9a) 109702078(Wnt9b)
OCU: 100352227(WNT9A) 100353559(WNT9B)
TUP: 102489417(WNT9B) 102496226(WNT9A)
CFA: 482209(WNT9A) 490919(WNT9B)
VVP: 112911976(WNT9A) 112920632(WNT9B)
AML: 100472460(WNT9B) 100475103(WNT9A)
UMR: 103665888(WNT9B) 103678871(WNT9A)
UAH: 113247507(WNT9A)
ORO: 101375113(WNT9B) 101377699(WNT9A)
FCA: 101080844(WNT9B) 111560436(WNT9A)
PTG: 102950323(WNT9A) 102962257(WNT9B)
PPAD: 109259601(WNT9A) 109259736(WNT9B)
AJU: 106985205(WNT9A) 106988831(WNT9B)
BTA: 511308(WNT9A) 541243(WNT9B)
BOM: 102278321(WNT9A) 102283149(WNT9B)
BIU: 109560806(WNT9A)
BBUB: 102410973(WNT9A) 102413713(WNT9B)
CHX: 102169419(WNT9B) 102184896(WNT9A)
OAS: 101102060(WNT9A)
SSC: 100512949(WNT9A) 100738655(WNT9B)
CFR: 102513485(WNT9A) 102514532(WNT9B)
CDK: 105090501(WNT9B) 105094161(WNT9A)
BACU: 103012928(WNT9A) 103020386(WNT9B)
LVE: 103081263(WNT9B) 103087468(WNT9A)
OOR: 101280238(WNT9B) 101282876(WNT9A)
DLE: 111169279(WNT9A) 111182925(WNT9B)
PCAD: 102973614(WNT9B) 102990829(WNT9A)
ECB: 100061110(WNT9A) 100063730(WNT9B)
EPZ: 103554698(WNT9B) 103565875(WNT9A)
EAI: 106821810(WNT9A) 106836490(WNT9B)
MYB: 102240485(WNT9B) 102244068(WNT9A)
MYD: 102765562(WNT9A) 102767329(WNT9B)
MNA: 107529865(WNT9A) 107530990(WNT9B)
HAI: 109380276(WNT9B) 109392784(WNT9A)
DRO: 112304972(WNT9A) 112316510(WNT9B)
PALE: 102884543(WNT9A) 102885223
RAY: 107508172(WNT9B) 107509675(WNT9A)
MJV: 108388856(WNT9B) 108398815(WNT9A)
LAV: 100658979(WNT9B) 100662057(WNT9A)
MDO: 100024657(WNT9B) 100025627(WNT9A)
SHR: 100914365(WNT9A) 100919162(WNT9B)
PCW: 110215901(WNT9B) 110217115(WNT9A)
OAA: 100074117(WNT9A)
GGA: 395829(WNT9A) 771092(WNT9B)
MGP: 100540276(WNT9A) 100549597(WNT9B)
CJO: 107308824(WNT9A) 107324983(WNT9B)
NMEL: 110388636(WNT9B) 110393842(WNT9A)
APLA: 101803319(WNT9A) 101804224(WNT9B)
ACYG: 106036786(WNT9A) 106049231(WNT9B)
TGU: 100230344(WNT9B) 100231300(WNT9A)
LSR: 110475711(WNT9A) 110482329(WNT9B)
SCAN: 103812676(WNT9A) 103821788(WNT9B)
GFR: 102036952(WNT9A) 102040292(WNT9B)
FAB: 101812024(WNT9A) 101819118(WNT9B)
PHI: 102099420(WNT9B) 102114245(WNT9A)
PMAJ: 107201011(WNT9A) 107215103(WNT9B)
CCAE: 111925470(WNT9A) 111940044(WNT9B)
CCW: 104686381(WNT9A) 104698528(WNT9B)
ETL: 114067380(WNT9B) 114068859(WNT9A)
FPG: 101910323(WNT9A) 101912498(WNT9B)
FCH: 102049155(WNT9B) 102052387(WNT9A)
CLV: 102088068(WNT9B) 102092974(WNT9A)
EGZ: 104126011(WNT9B) 104127431(WNT9A)
NNI: 104017402(WNT9B) 104021728(WNT9A)
ACUN: 113476677(WNT9A) 113489203(WNT9B)
PADL: 103920640(WNT9B) 103924706(WNT9A)
AAM: 106487678(WNT9A) 106496688(WNT9B)
ASN: 102369665(WNT9A) 102381043(WNT9B)
AMJ: 102567669(WNT9B) 102569365(WNT9A)
PSS: 102452951(WNT9A) 102459581(WNT9B)
CMY: 102933541(WNT9A) 102940629(WNT9B)
CPIC: 101945621(WNT9A) 101953294(WNT9B)
ACS: 100554651(wnt9a) 100560587(wnt9b)
PVT: 110081358(WNT9B) 110085099(WNT9A)
PBI: 103050902(WNT9A) 103063074(WNT9B)
PMUR: 107285998(WNT9A) 107303007(WNT9B)
TSR: 106542568(WNT9A) 106547623(WNT9B)
PMUA: 114582220(WNT9B) 114607483(WNT9A)
GJA: 107120477(WNT9A) 107125522(WNT9B)
XLA: 100462916(wnt9a.S) 100462925(wnt9b.2.L) 108702571 108719801
XTR: 100125200(wnt9b) 101734951(wnt9a)
NPR: 108788785(WNT9A) 108797410(WNT9B)
DRE: 565677(wnt9b) 751644(wnt9a)
IPU: 108259511 108267524(wnt9a)
PHYP: 113524133(wnt9a) 113527956(wnt9b)
AMEX: 103034815(wnt9a) 103044946(wnt9b)
EEE: 113589912 113590801(wnt9a)
TRU: 101062131(wnt9a) 101068819(wnt9b)
LCO: 104923918 109140386(wnt9a)
NCC: 104944884(wnt9b) 104963889(wnt9a)
MZE: 101471472(wnt9b) 101472696(wnt9a)
ONL: 100694832(wnt9a) 100706905(wnt9b)
OLA: 101155800(wnt9a) 101173867
XMA: 102223878 102226011(wnt9a)
XCO: 114147152(wnt9a) 114160271
PRET: 103468657(wnt9b) 103479706(wnt9a)
CVG: 107084750(wnt9b) 107101620
NFU: 107378473 107383854(wnt9a)
KMR: 108241624(wnt9a) 108246125
ALIM: 106533315(wnt9a) 106537331
AOCE: 111568658(wnt9a) 111581687(wnt9b)
CSEM: 103392609 103396378(wnt9a)
POV: 109634121 109638132(wnt9a)
LCF: 108883358(wnt9a) 108900850(wnt9b)
SDU: 111217603 111231190(wnt9a)
SLAL: 111653285(wnt9a) 111660446
HCQ: 109519316(wnt9b) 109521360(wnt9a)
BPEC: 110159794(wnt9a) 110168900(wnt9b)
MALB: 109952694(wnt9a) 109964218(wnt9b)
ELS: 105013207(wnt9b) 105019734(wnt9a)
SFM: 108928149 108937634(wnt9a)
PKI: 111832887 111845981(wnt9a)
LCM: 102355045(WNT9B) 102360464(WNT9A)
CMK: 103187750(wnt9b)
RTP: 109911827(wnt9a) 109917374
BFO: 118405794
CIN: 100175210
APLC: 110983723
SKO: 100313766(Wnt9)
DPE: 6589632
DWI: 6644101
DAZ: 108611415
DNV: 115562224
DHE: 111601061
LCQ: 111690737
AAG: 5573817
TCA: 656264(Wnt9)
NVL: 108563645
BMOR: 101738490
BMAN: 114249249
PRAP: 110994224
HAW: 110371114
TNL: 113501290
CLEC: 106666731
ZNE: 110828857
DPX: DAPPUDRAFT_290643(WNT9)
PVM: 113819684
CSCU: 111629170
PCAN: 112559551
CRG: 105347794
MYI: 110462055
OBI: 106882622
LAK: 106180549
 » show all
Reference
  Authors
Saitoh T, Hirai M, Katoh M
  Title
Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region.
  Journal
Biochem Biophys Res Commun 284:1168-75 (2001)
DOI:10.1006/bbrc.2001.5105
  Sequence
[hsa:7483]
Reference
  Authors
Qian J, Jiang Z, Li M, Heaphy P, Liu YH, Shackleford GM
  Title
Mouse Wnt9b transforming activity, tissue-specific expression, and evolution.
  Journal
Genomics 81:34-46 (2003)
DOI:10.1016/S0888-7543(02)00012-5
  Sequence
[mmu:22412]
LinkDB

KEGG   ORTHOLOGY: K01357
Entry
K01357                      KO                                     

Name
WNT10
Definition
wingless-type MMTV integration site family, member 10
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00471  Split-hand/foot malformation
H00625  Tooth agenesis
H00646  Odontoonychodermal dysplasia
H00781  Schopf-Schulz-Passarge syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   04390 Hippo signaling pathway
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   04150 mTOR signaling pathway
    K01357  WNT10; wingless-type MMTV integration site family, member 10
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K01357  WNT10; wingless-type MMTV integration site family, member 10
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K01357  WNT10; wingless-type MMTV integration site family, member 10
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   05205 Proteoglycans in cancer
    K01357  WNT10; wingless-type MMTV integration site family, member 10
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   05226 Gastric cancer
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   05217 Basal cell carcinoma
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   05224 Breast cancer
    K01357  WNT10; wingless-type MMTV integration site family, member 10
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K01357  WNT10; wingless-type MMTV integration site family, member 10
   05022 Pathways of neurodegeneration - multiple diseases
    K01357  WNT10; wingless-type MMTV integration site family, member 10
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K01357  WNT10; wingless-type MMTV integration site family, member 10
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K01357  WNT10; wingless-type MMTV integration site family, member 10
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K01357  WNT10; wingless-type MMTV integration site family, member 10
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K01357  WNT10; wingless-type MMTV integration site family, member 10
Genes
HSA: 7480(WNT10B) 80326(WNT10A)
PTR: 451870(WNT10B) 459952(WNT10A)
PPS: 100988140(WNT10A) 100995123(WNT10B)
GGO: 101132868(WNT10A) 101142818(WNT10B)
PON: 100440744(WNT10B) 100441013(WNT10A)
NLE: 100587640(WNT10B) 100607164(WNT10A)
MCC: 700692(WNT10A) 708906(WNT10B)
MCF: 102121241(WNT10B) 102133672(WNT10A)
CSAB: 103217886(WNT10A) 103238252(WNT10B)
RRO: 104660037(WNT10A) 104679730(WNT10B)
RBB: 108518480(WNT10A) 108543904(WNT10B)
CJC: 100388949(WNT10B) 100395222(WNT10A)
SBQ: 101029432(WNT10A) 101043819(WNT10B)
MMU: 22409(Wnt10a) 22410(Wnt10b)
MCAL: 110300434(Wnt10a) 110310912(Wnt10b)
MPAH: 110322230(Wnt10a) 110335137(Wnt10b)
RNO: 315294(Wnt10b) 316527(Wnt10a)
MUN: 110547434(Wnt10b) 110566381(Wnt10a)
CGE: 100766340(Wnt10b) 100770174(Wnt10a)
NGI: 103727730(Wnt10a) 103750565(Wnt10b)
HGL: 101699309(Wnt10a) 101722280(Wnt10b)
CCAN: 109693094(Wnt10a) 109694821(Wnt10b)
OCU: 100351316(WNT10B) 100352839(WNT10A)
TUP: 102481567(WNT10B) 102483253(WNT10A)
CFA: 486561(WNT10B) 488528(WNT10A)
VVP: 112921097(WNT10B) 112922477(WNT10A)
AML: 100467643 100475265(WNT10B)
UMR: 103662888(WNT10A) 103675452(WNT10B)
UAH: 113248677(WNT10A) 113257662(WNT10B)
ORO: 101370799(WNT10B) 101375180(WNT10A)
FCA: 101092455(WNT10A) 101093948(WNT10B)
PTG: 102956294(WNT10A) 102961987(WNT10B)
PPAD: 109249054(WNT10B) 109265050(WNT10A)
AJU: 106969331(WNT10B) 106970053(WNT10A)
BTA: 537330(WNT10A) 539337(WNT10B)
BOM: 102267865(WNT10B) 102276805(WNT10A)
BIU: 109559150(WNT10B) 109570791(WNT10A)
BBUB: 102404088(WNT10B) 102406713(WNT10A)
CHX: 102169259(WNT10B) 102177945(WNT10A)
OAS: 101102299(WNT10B) 101113129(WNT10A)
SSC: 100126276(WNT10B) 100623646(WNT10A)
CFR: 102511822(WNT10A) 102514687(WNT10B)
CDK: 105096132(WNT10A) 105103814(WNT10B)
BACU: 103000687(WNT10A) 103016899(WNT10B)
LVE: 103078356(WNT10B) 103078970(WNT10A)
OOR: 101270797(WNT10B) 101287762(WNT10A)
DLE: 111172091(WNT10A) 111174054(WNT10B)
PCAD: 102983815(WNT10B) 102992887(WNT10A)
ECB: 100051649(WNT10B) 111773843(WNT10A)
EPZ: 103552222(WNT10B) 103567916(WNT10A)
EAI: 106836816(WNT10B) 106838468(WNT10A)
MYB: 102245559(WNT10B) 102256067(WNT10A)
MYD: 102762164(WNT10A) 102765167(WNT10B)
MNA: 107524821(WNT10A) 107528238(WNT10B)
HAI: 109380555(WNT10A) 109393213(WNT10B)
DRO: 112308080(WNT10A) 112318480(WNT10B)
PALE: 102882121(WNT10A) 102888263(WNT10B)
RAY: 107514289(WNT10B) 107516694(WNT10A)
MJV: 108383428(WNT10B) 108390506(WNT10A)
LAV: 100655805(WNT10B) 100674782(WNT10A)
MDO: 100010973(WNT10A)
SHR: 100917765(WNT10A) 100932979(WNT10B)
PCW: 110194132(WNT10B) 110219504(WNT10A)
OAA: 100090678(WNT10A) 107547159(WNT10B)
GGA: 429040(WNT10A)
MGP: 100539047(WNT10A)
CJO: 107317039(WNT10A)
NMEL: 110399929(WNT10A)
APLA: 101803237(WNT10A)
ACYG: 106039312(WNT10A)
TGU: 100226575(WNT10A)
LSR: 110468404(WNT10A)
SCAN: 103814357(WNT10A)
GFR: 102035663(WNT10A)
FAB: 101820020(WNT10A)
PHI: 102101018(WNT10A)
PMAJ: 107207278(WNT10A)
CCAE: 111922556(WNT10A)
CCW: 104694193(WNT10A)
ETL: 114055327(WNT10A)
FPG: 101912556(WNT10A)
FCH: 102046955(WNT10A)
CLV: 102085904(WNT10A)
EGZ: 104132431(WNT10A)
NNI: 104010099(WNT10A)
ACUN: 113482131(WNT10A)
PADL: 103917681(WNT10A)
AAM: 106499075(WNT10A)
ASN: 102377468(WNT10A)
AMJ: 102563189(WNT10A)
PSS: 102450035(WNT10B)
CMY: 102937268(WNT10A) 102943508(WNT10B)
CPIC: 101943134(WNT10A) 101951470(WNT10B)
ACS: 100556196(wnt10a) 107982255
PVT: 110075268(WNT10B) 110078221(WNT10A)
PBI: 103052824(WNT10B) 103054693(WNT10A)
PMUR: 107292514(WNT10A) 107298589
TSR: 106540756(WNT10A) 106549321
PMUA: 114592957(WNT10B) 114603070(WNT10A)
GJA: 107120884(WNT10B)
XLA: 100049784(wnt10a.L) 108702936(wnt10a.S) 108708545(wnt10b.L) 108709816
XTR: 100485724(wnt10a) 780228(wnt10b)
NPR: 108791400(WNT10B) 108802066
DRE: 30171(wnt10a) 30308(wnt10b)
IPU: 108266076(wnt10a) 108276208
PHYP: 113530641(wnt10b) 113547113(wnt10a)
AMEX: 103039496(wnt10b) 103044775(wnt10a)
EEE: 113584450(wnt10b) 113591173(wnt10a)
TRU: 101061404(wnt10b) 101062670(wnt10a)
LCO: 104919614(wnt10a) 104932464(wnt10b)
NCC: 104942513 104956880(wnt10b)
MZE: 101464338(wnt10b) 101473879(wnt10a)
ONL: 100695291(wnt10a) 100710675(wnt10b)
OLA: 101170092(wnt10b) 101174473(wnt10a)
XMA: 102225187(wnt10b) 102234428(wnt10a)
XCO: 114142645(wnt10b) 114148345(wnt10a)
PRET: 103460520 103467361(wnt10b)
CVG: 107091476(wnt10b) 107092652
NFU: 107390191(wnt10a) 107390892(wnt10b)
KMR: 108235197(wnt10b) 108238564(wnt10a)
ALIM: 106523159(wnt10a) 106524799
AOCE: 111581749(wnt10a) 111581814(wnt10b)
CSEM: 103385100(wnt10b) 103392497(wnt10a)
POV: 109630839(wnt10b) 109631077(wnt10a)
LCF: 108876563(wnt10b) 108902829(wnt10a)
SDU: 111218392(wnt10a) 111219026(wnt10b)
SLAL: 111668742(wnt10a) 111669053(wnt10b)
HCQ: 109522340(wnt10a) 109531337(wnt10b)
BPEC: 110156113(wnt10a) 110164858(wnt10b)
MALB: 109964405(wnt10a) 109969873(wnt10b)
ELS: 105013556(wnt10b) 105029532(wnt10a)
LCM: 102352380(WNT10A) 102354275(WNT10B)
CMK: 103190983(wnt10b)
RTP: 109913259(wnt10a) 109922859
BFO: 118405723
SPU: 576131
APLC: 110983430
SKO: 100329012(Wnt10)
DME: Dmel_CG4971(Wnt10)
DER: 6543046
DSE: 6611517
DSI: Dsimw501_GD23462(Dsim_GD23462)
DAN: 6498658
DSR: 110182688
DPE: 6589313
DMN: 108161552
DWI: 6644098
DAZ: 108611428
DNV: 115562266
DHE: 111602183
DVI: 6628630
MDE: 101896418
LCQ: 111688838
AAG: 5564833
AME: 413500
BIM: 100742836
BTER: 100647715
CCAL: 108622245
OBB: 114871799
SOC: 105200051
MPHA: 105838833
AEC: 105150856
ACEP: 105618732
PBAR: 105429523
VEM: 105566205
HST: 105189297
DQU: 106746482
CFO: 105258969
LHU: 105676111
PGC: 109859099
OBO: 105285350
PCF: 106784989
NVI: 100119505
CSOL: 105367718
TCA: 656598(Wnt10)
ATD: 109604840
NVL: 108563686
BMAN: 114247154
PMAC: 106714245
PRAP: 110994218
HAW: 110371089
TNL: 113501321
PXY: 105397909
BTAB: 109044612
CLEC: 106666840
ZNE: 110828861
FCD: 110845148
DPX: DAPPUDRAFT_290646(WNT10)
PVM: 113827308
PCAN: 112574074
CRG: 105348240
MYI: 110442897
OBI: 106878304(Wnt10)
NVE: 5508894
EPA: 110250757
ADF: 107333379
AMIL: 114957171
PDAM: 113671499
SPIS: 111330936
 » show all
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells.
  Journal
Biochem Biophys Res Commun 283:798-805 (2001)
DOI:10.1006/bbrc.2001.4855
  Sequence
[hsa:80326]
Reference
PMID:9284937
  Authors
Hardiman G, Kastelein RA, Bazan JF
  Title
Isolation, characterization and chromosomal localization of human WNT10B.
  Journal
Cytogenet Cell Genet 77:278-82 (1997)
DOI:10.1159/000134597
  Sequence
[hsa:7480]
Reference
  Authors
Lekven AC, Buckles GR, Kostakis N, Moon RT
  Title
Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.
  Journal
Dev Biol 254:172-87 (2003)
DOI:10.1016/S0012-1606(02)00044-1
  Sequence
[dre:30308]
LinkDB

KEGG   ORTHOLOGY: K01384
Entry
K01384                      KO                                     

Name
WNT11
Definition
wingless-type MMTV integration site family, member 11
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   04390 Hippo signaling pathway
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   04150 mTOR signaling pathway
    K01384  WNT11; wingless-type MMTV integration site family, member 11
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K01384  WNT11; wingless-type MMTV integration site family, member 11
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K01384  WNT11; wingless-type MMTV integration site family, member 11
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   05205 Proteoglycans in cancer
    K01384  WNT11; wingless-type MMTV integration site family, member 11
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   05226 Gastric cancer
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   05217 Basal cell carcinoma
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   05224 Breast cancer
    K01384  WNT11; wingless-type MMTV integration site family, member 11
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K01384  WNT11; wingless-type MMTV integration site family, member 11
   05022 Pathways of neurodegeneration - multiple diseases
    K01384  WNT11; wingless-type MMTV integration site family, member 11
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K01384  WNT11; wingless-type MMTV integration site family, member 11
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K01384  WNT11; wingless-type MMTV integration site family, member 11
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K01384  WNT11; wingless-type MMTV integration site family, member 11
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K01384  WNT11; wingless-type MMTV integration site family, member 11
Genes
HSA: 7481(WNT11)
PTR: 451431(WNT11)
PPS: 100989115(WNT11)
GGO: 101128994(WNT11)
PON: 100443554(WNT11)
NLE: 100594864(WNT11)
MCC: 696845(WNT11)
MCF: 102130649(WNT11)
CSAB: 103248071(WNT11)
RRO: 104665095(WNT11)
RBB: 108527394(WNT11)
CJC: 100398625(WNT11)
SBQ: 101050295(WNT11)
MMU: 22411(Wnt11)
MCAL: 110298907(Wnt11)
MPAH: 110325401(Wnt11)
RNO: 140584(Wnt11)
MUN: 110562445(Wnt11)
CGE: 100774690(Wnt11)
NGI: 103743015(Wnt11)
HGL: 101697582(Wnt11)
CCAN: 109698403(Wnt11)
OCU: 100009030(WNT11)
TUP: 102494826(WNT11)
CFA: 485183(WNT11)
VVP: 112928634(WNT11)
AML: 100468561(WNT11)
UMR: 103678127(WNT11)
UAH: 113269338(WNT11)
ORO: 101386420(WNT11)
ELK: 111159478
FCA: 101100080(WNT11)
PTG: 102971675(WNT11)
PPAD: 109267221(WNT11)
AJU: 106976446(WNT11)
BTA: 613288(WNT11)
BOM: 102266913(WNT11)
BIU: 109569843(WNT11)
BBUB: 102409223(WNT11)
CHX: 102175498(WNT11)
OAS: 101111048(WNT11)
SSC: 100521912(WNT11)
CFR: 102508550(WNT11)
CDK: 105097257(WNT11)
BACU: 103016115(WNT11)
LVE: 103091035(WNT11)
OOR: 101284277(WNT11)
DLE: 111184814(WNT11)
PCAD: 102987189(WNT11)
ECB: 100064184(WNT11)
EPZ: 103548228(WNT11)
EAI: 106840396(WNT11)
MYB: 102243634(WNT11)
MYD: 102755181(WNT11)
MNA: 107524451(WNT11)
HAI: 109386296(WNT11)
DRO: 112315988(WNT11)
PALE: 102877879(WNT11)
RAY: 107519202(WNT11)
MJV: 108405770(WNT11)
LAV: 100656630(WNT11)
TMU: 101340313
MDO: 100028529(WNT11)
SHR: 100913767(WNT11)
PCW: 110210555(WNT11)
OAA: 100091700(WNT11)
GGA: 100170842(WNT11B) 395562(WNT11)
MGP: 100538380 100544486(WNT11)
CJO: 107308524(WNT11) 107312604
NMEL: 110391565(WNT11) 110403401
APLA: 101798327(WNT11)
ACYG: 106042380(WNT11) 106042950
TGU: 100226560 100229189(WNT11)
LSR: 110471642(WNT11) 110474380
SCAN: 103816564 103823763(WNT11)
GFR: 102036206(WNT11) 102037571
FAB: 101811302(WNT11) 101815984
PHI: 102101906 102107422(WNT11)
PMAJ: 107203639 107211829(WNT11)
CCAE: 111928735 111941032(WNT11)
CCW: 104686964(WNT11) 104691341
ETL: 114059658(WNT11) 114065165
FCH: 102047808 102052267(WNT11)
CLV: 102085160 102087258(WNT11)
EGZ: 104124767(WNT11) 104135990
NNI: 104012837 104022726(WNT11)
ACUN: 113480098 113486194(WNT11)
PADL: 103915171(WNT11) 103919182
AAM: 106486175 106495859(WNT11)
ASN: 102370312(WNT11)
AMJ: 102558673(WNT11B) 102569158(WNT11)
PSS: 102449564 102453776(WNT11)
CMY: 102929745 102932211(WNT11)
CPIC: 101932131(WNT11) 101941719
ACS: 100553134(wnt11)
PVT: 110087792(WNT11)
PBI: 103063684
PMUA: 114589509 114595555(WNT11)
GJA: 107122166(WNT11)
XLA: 108708822 399441(wnt11b.L) 446915(wnt11.L)
XTR: 100158655(wnt11) 493495(wnt11) 549489(wnt11b)
NPR: 108785620 108792518(WNT11)
DRE: 30283(wnt11) 791595(wnt11f2)
IPU: 108259816 108277378(wnt11)
PHYP: 113524168
TRU: 101078737(wnt11)
LCO: 104933905(wnt11)
NCC: 104956246(wnt11)
MZE: 101484274(wnt11)
ONL: 100708759(wnt11)
OLA: 101155217(wnt11)
XMA: 102220098(wnt11)
XCO: 114153021(wnt11)
PRET: 103476126(wnt11)
CVG: 107101790(wnt11)
NFU: 107386013(wnt11)
KMR: 108244722(wnt11)
ALIM: 106517206(wnt11)
AOCE: 111576265(wnt11)
CSEM: 103394821(wnt11)
POV: 109647026
LCF: 108893672(wnt11)
SDU: 111222287(wnt11)
SLAL: 111663496(wnt11)
HCQ: 109531176(wnt11)
BPEC: 110165118(wnt11)
MALB: 109972882(wnt11)
ELS: 105010980(wnt11) 105025046
SFM: 108931012 108936094(wnt11)
PKI: 111835532 111858442(wnt11)
LCM: 102358867 102362969(WNT11)
BFO: 118427476
SKO: 100313541(Wnt11)
AME: 725511
BIM: 100746902
BTER: 100646489
CCAL: 108626710
OBB: 114880648
SOC: 105205612
MPHA: 105836222
AEC: 105146334
ACEP: 105618227
PBAR: 105433968
VEM: 105569615
HST: 105180551
DQU: 106744703
CFO: 105259241
PGC: 109857398
OBO: 105283955
PCF: 106787116
NVI: 100679139
CSOL: 105366203
MDL: 103571124
TCA: 657726(Wnt11)
DPA: 109534721
NVL: 108566016
BMOR: 101744696
BMAN: 114241682
PMAC: 106712368
PRAP: 110995501
HAW: 110371679
TNL: 113492733
PXY: 105388528
AGS: 114120361
RMD: 113557174
BTAB: 109044333
ZNE: 110827247
DPX: DAPPUDRAFT_290647(WNTY)
PVM: 113825448
TSP: Tsp_04250
PCAN: 112555463
CRG: 105322578
EGL: EGR_00445
HMG: 100197163(hywnt11)
AQU: 100636289
 » show all
Reference
  Authors
Kirikoshi H, Sekihara H, Katoh M
  Title
Molecular cloning and characterization of human WNT11.
  Journal
Int J Mol Med 8:651-6 (2001)
DOI:10.3892/ijmm.8.6.651
  Sequence
[hsa:7481]
Reference
  Authors
Matthews HK, Broders-Bondon F, Thiery JP, Mayor R
  Title
Wnt11r is required for cranial neural crest migration.
  Journal
Dev Dyn 237:3404-9 (2008)
DOI:10.1002/dvdy.21758
  Sequence
[xla:446915]
LinkDB

KEGG   ORTHOLOGY: K01558
Entry
K01558                      KO                                     

Name
WNT16
Definition
wingless-type MMTV integration site family, member 16
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   04390 Hippo signaling pathway
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   04150 mTOR signaling pathway
    K01558  WNT16; wingless-type MMTV integration site family, member 16
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K01558  WNT16; wingless-type MMTV integration site family, member 16
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K01558  WNT16; wingless-type MMTV integration site family, member 16
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05202 Transcriptional misregulation in cancer
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05205 Proteoglycans in cancer
    K01558  WNT16; wingless-type MMTV integration site family, member 16
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05226 Gastric cancer
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05217 Basal cell carcinoma
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05224 Breast cancer
    K01558  WNT16; wingless-type MMTV integration site family, member 16
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K01558  WNT16; wingless-type MMTV integration site family, member 16
   05022 Pathways of neurodegeneration - multiple diseases
    K01558  WNT16; wingless-type MMTV integration site family, member 16
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K01558  WNT16; wingless-type MMTV integration site family, member 16
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K01558  WNT16; wingless-type MMTV integration site family, member 16
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K01558  WNT16; wingless-type MMTV integration site family, member 16
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K01558  WNT16; wingless-type MMTV integration site family, member 16
Genes
HSA: 51384(WNT16)
PTR: 737375(WNT16)
PPS: 100985948(WNT16)
GGO: 101138602(WNT16)
PON: 100452466(WNT16)
NLE: 100605294(WNT16)
MCC: 694069(WNT16)
MCF: 102142460(WNT16)
CSAB: 103226795(WNT16)
RRO: 104677318(WNT16)
RBB: 108518499(WNT16)
CJC: 100387388(WNT16)
SBQ: 101032778(WNT16)
MMU: 93735(Wnt16)
MCAL: 110296883(Wnt16)
MPAH: 110317136(Wnt16)
RNO: 500047(Wnt16)
MUN: 110559723(Wnt16)
CGE: 100764115(Wnt16)
NGI: 103730604(Wnt16)
HGL: 101710484(Wnt16)
CCAN: 109685536(Wnt16)
OCU: 100353090(WNT16)
TUP: 102497530(WNT16)
CFA: 612328(WNT16)
VVP: 112910612(WNT16)
AML: 100464171(WNT16)
UMR: 103676602(WNT16)
UAH: 113266506(WNT16)
ORO: 101381671(WNT16)
ELK: 111152110
FCA: 101090252(WNT16)
PTG: 102959880(WNT16)
PPAD: 109268901(WNT16)
AJU: 106970656(WNT16)
BTA: 538627(WNT16)
BOM: 102274851(WNT16)
BBUB: 102404380(WNT16)
CHX: 102191205(WNT16)
OAS: 101103229(WNT16)
SSC: 100511484(WNT16)
CFR: 102505757(WNT16)
CDK: 105085333(WNT16)
BACU: 103018475(WNT16)
LVE: 103085163(WNT16)
OOR: 101286771(WNT16)
DLE: 111179093(WNT16)
PCAD: 102994549(WNT16)
ECB: 100071393(WNT16)
EPZ: 103564131(WNT16)
EAI: 106829817(WNT16)
MYB: 102247057(WNT16)
MYD: 102773494(WNT16)
MNA: 107537386(WNT16)
HAI: 109371280(WNT16)
DRO: 112299924(WNT16)
PALE: 102882050(WNT16)
RAY: 107500238(WNT16)
MJV: 108406833(WNT16)
LAV: 100659037(WNT16)
TMU: 101359317
MDO: 100012964(WNT16)
SHR: 100921973(WNT16)
PCW: 110194197(WNT16)
OAA: 100077974(WNT16)
GGA: 427856(WNT16)
MGP: 100544116(WNT16)
CJO: 107308732(WNT16)
NMEL: 110392567(WNT16)
APLA: 101795639(WNT16)
ACYG: 106044517(WNT16)
TGU: 100218349(WNT16)
LSR: 110483518(WNT16)
SCAN: 103813687(WNT16)
GFR: 102041852(WNT16)
FAB: 101809098(WNT16)
PHI: 102099681(WNT16)
PMAJ: 107204762(WNT16)
CCAE: 111923048(WNT16)
CCW: 104686900(WNT16)
ETL: 114068511(WNT16)
FPG: 101924697(WNT16)
FCH: 102051265(WNT16)
CLV: 102095964(WNT16)
EGZ: 104125658(WNT16)
NNI: 104011840(WNT16)
ACUN: 113491231(WNT16)
PADL: 103923858(WNT16)
AAM: 106495936(WNT16)
ASN: 102371518(WNT16)
AMJ: 102559691(WNT16)
PSS: 102452741(WNT16)
CMY: 102935351(WNT16)
CPIC: 101931805(WNT16)
ACS: 100553645(wnt16)
PVT: 110086434(WNT16)
PBI: 103065188(WNT16)
PMUR: 107293140(WNT16)
TSR: 106541892(WNT16)
PMUA: 114605736(WNT16)
GJA: 107111117(WNT16)
XLA: 108711143(wnt16.L) 108713100(wnt16.S)
XTR: 100125197(wnt16)
NPR: 108788024(WNT16)
DRE: 791563(wnt16)
IPU: 108279512(wnt16)
PHYP: 113531841(wnt16)
AMEX: 107197694(wnt16)
EEE: 113582698(wnt16)
TRU: 101072879(wnt16)
LCO: 104934562(wnt16)
ONL: 100701833(wnt16)
OLA: 101164219(wnt16)
XMA: 102232574(wnt16)
XCO: 114160866(wnt16)
PRET: 103459813(wnt16)
CVG: 107100773(wnt16)
NFU: 107372976(wnt16)
KMR: 108248428(wnt16)
AOCE: 111585203(wnt16)
CSEM: 103382461(wnt16)
POV: 109641652(wnt16)
LCF: 108892099(wnt16)
SDU: 111229503(wnt16)
SLAL: 111647701(wnt16)
HCQ: 109532566(wnt16)
BPEC: 110161906(wnt16)
MALB: 109967699(wnt16)
SALP: 111951403(wnt16)
ELS: 105006926(wnt16)
SFM: 108920795(wnt16)
PKI: 111844339(wnt16)
LCM: 102346469(WNT16)
CMK: 103186123(wnt16)
RTP: 109935971(wnt16)
BFO: 118415996
SPU: 591980
APLC: 110986453
SKO: 100370081
API: 100159117
DNX: 107169001
AGS: 114123248
RMD: 113557056
ZNE: 110832567
FCD: 110856658
DPX: DAPPUDRAFT_48424(WNT16)
PVM: 113829497
TUT: 107367082
CSCU: 111625292
PTEP: 107457243
CEL: CELE_W08D2.1(egl-20)
CBR: CBG03476(Cbr-egl-20)
TSP: Tsp_02499
PCAN: 112572255
CRG: 105325704
MYI: 110443365
OBI: 106871965
LAK: 106162451
NVE: 5512558
EPA: 110242531
ADF: 107343837
PDAM: 113668724
 » show all
Reference
  Authors
Fear MW, Kelsell DP, Spurr NK, Barnes MR
  Title
Wnt-16a, a novel Wnt-16 isoform, which shows differential expression in adult human tissues.
  Journal
Biochem Biophys Res Commun 278:814-20 (2000)
DOI:10.1006/bbrc.2000.3852
  Sequence
[hsa:51384]
LinkDB

KEGG   ORTHOLOGY: K03209
Entry
K03209                      KO                                     

Name
WNT1
Definition
wingless-type MMTV integration site family, member 1
Pathway
ko04150  mTOR signaling pathway
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04916  Melanogenesis
ko04934  Cushing syndrome
ko05010  Alzheimer disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05165  Human papillomavirus infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05217  Basal cell carcinoma
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Disease
H00506  Osteogenesis imperfecta
H01593  Osteoporosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   04390 Hippo signaling pathway
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   04391 Hippo signaling pathway - fly
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   04150 mTOR signaling pathway
    K03209  WNT1; wingless-type MMTV integration site family, member 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K03209  WNT1; wingless-type MMTV integration site family, member 1
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    K03209  WNT1; wingless-type MMTV integration site family, member 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   05205 Proteoglycans in cancer
    K03209  WNT1; wingless-type MMTV integration site family, member 1
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   05226 Gastric cancer
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   05217 Basal cell carcinoma
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   05224 Breast cancer
    K03209  WNT1; wingless-type MMTV integration site family, member 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03209  WNT1; wingless-type MMTV integration site family, member 1
   05022 Pathways of neurodegeneration - multiple diseases
    K03209  WNT1; wingless-type MMTV integration site family, member 1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K03209  WNT1; wingless-type MMTV integration site family, member 1
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K03209  WNT1; wingless-type MMTV integration site family, member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K03209  WNT1; wingless-type MMTV integration site family, member 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Morphogens
   K03209  WNT1; wingless-type MMTV integration site family, member 1
Genes
HSA: 7471(WNT1)
PTR: 742674(WNT1)
PPS: 100995465(WNT1)
GGO: 101143181(WNT1)
PON: 100441356(WNT1)
NLE: 100587307(WNT1)
MCC: 709009(WNT1)
MCF: 102120871(WNT1)
CSAB: 103238251(WNT1)
RRO: 104679729(WNT1)
RBB: 108543922(WNT1)
CJC: 100389319(WNT1)
SBQ: 101044133(WNT1)
MMU: 22408(Wnt1)
MCAL: 110310964(Wnt1)
MPAH: 110335204(Wnt1)
RNO: 24881(Wnt1)
MUN: 110547435(Wnt1)
CGE: 100766046(Wnt1)
NGI: 103750567(Wnt1)
HGL: 101722636(Wnt1)
CCAN: 109694825(Wnt1)
OCU: 100354018(WNT1)
TUP: 102499190(WNT1)
CFA: 486560(WNT1)
VVP: 112921098(WNT1)
AML: 100475007(WNT1)
UMR: 103675620(WNT1)
UAH: 113257365(WNT1)
ORO: 101370511(WNT1)
ELK: 111158015
FCA: 101094190(WNT1)
PTG: 102962277(WNT1)
PPAD: 109249055(WNT1)
AJU: 106969330(WNT1)
BTA: 540662(WNT1)
BOM: 102268143(WNT1)
BIU: 109558697(WNT1)
BBUB: 102403747(WNT1)
CHX: 102180014(WNT1)
OAS: 101103389(WNT1)
SSC: 100525462(WNT1)
CFR: 102521780(WNT1)
CDK: 105103785(WNT1)
BACU: 103017176(WNT1)
LVE: 103078640(WNT1)
OOR: 101270541(WNT1)
DLE: 111174055(WNT1)
PCAD: 102983530(WNT1)
ECB: 100058859(WNT1)
EPZ: 103552200(WNT1)
EAI: 106836901(WNT1)
MYB: 102245856(WNT1)
MYD: 102764877(WNT1)
MNA: 107528239(WNT1)
HAI: 109393219(WNT1)
DRO: 112318261(WNT1)
PALE: 102888016(WNT1)
RAY: 107514294(WNT1)
MJV: 108383443(WNT1)
TMU: 101352160
MDO: 100032741(WNT1)
SHR: 100928059(WNT1)
PCW: 110194136(WNT1)
OAA: 114814562(WNT1)
GGA: 396160(WNT1)
MGP: 104916364
CJO: 107325739(WNT1)
ACYG: 106047715(WNT1)
TGU: 100229313(WNT1)
LSR: 110480394(WNT1)
SCAN: 103824623(WNT1)
GFR: 102033698(WNT1)
FAB: 101817901(WNT1)
PHI: 102103458(WNT1)
PMAJ: 107198589(WNT1)
CCAE: 111944514
ETL: 114071074(WNT1)
FPG: 101915237(WNT1)
FCH: 102049459(WNT1)
CLV: 102091634(WNT1)
AAM: 106497501(WNT1)
ASN: 102372844(WNT1)
AMJ: 102559781(WNT1)
PSS: 102450278(WNT1)
CMY: 102937737
CPIC: 101933470(WNT1)
ACS: 100562340(wnt1)
PVT: 110075264(WNT1)
PBI: 103053050(WNT1)
PMUR: 107287780(WNT1)
TSR: 106549320
PMUA: 114592956(WNT1)
GJA: 107120894(WNT1)
XLA: 108709815(wnt1.S) 373578(wnt1.L)
XTR: 100491444(wnt1)
NPR: 108791403(WNT1)
DRE: 30128(wnt1)
CCAR: 109065063(wnt1)
IPU: 108276209(wnt1)
PHYP: 113530642(wnt1)
AMEX: 103042266(wnt1)
EEE: 113584444(wnt1)
TRU: 101061628(wnt1)
LCO: 104932478(wnt1)
NCC: 104956879(wnt1)
MZE: 101475965(wnt1)
ONL: 100710411(wnt1)
OLA: 100125456(wnt1)
XMA: 102224929(wnt1)
XCO: 114148723(wnt1)
PRET: 103467362(wnt1)
CVG: 107091396(wnt1)
NFU: 107390891(wnt1)
KMR: 108235196(wnt1)
ALIM: 106524809(wnt1)
AOCE: 111581815(wnt1)
CSEM: 103385099(wnt1)
POV: 109630840(wnt1)
LCF: 108876564(wnt1)
SDU: 111219027(wnt1)
SLAL: 111668938(wnt1)
HCQ: 109531330(wnt1)
BPEC: 110164735(wnt1)
MALB: 109969901(wnt1)
OTW: 112221509 112247356(wnt1)
ELS: 105013565(wnt1)
SFM: 108939183
LCM: 102350033(WNT1)
CMK: 103189269(wnt1)
RTP: 109924630(wnt1)
BFO: 118405857
SPU: 373498(wnt1)
APLC: 110984810
SKO: 100303492(Wnt1)
DME: Dmel_CG4889(wg)
DER: 6543349
DSE: 6611514
DSI: Dsimw501_GD28595(Dsim_GD28595)
DAN: 6508748
DPO: Dpse_GA18504(Dpse_wg)
DPE: 6589316
DMN: 108162805
DWI: 6644100
DAZ: 108611685
DNV: 108657967
DHE: 111602339
DVI: 6628632
MDE: 101888781
LCQ: 111690738
AAG: 5573815
AME: 413502
BIM: 100748497
BTER: 100650550
CCAL: 108622300
OBB: 114871804
SOC: 105200047
MPHA: 105830159
AEC: 105150858
ACEP: 105618733
PBAR: 105429521
VEM: 105566203
HST: 105189237
DQU: 106746498
CFO: 105258973
LHU: 105676098
PGC: 109859093
OBO: 105285318
PCF: 106792535
NVI: 100119654
CSOL: 105367696
MDL: 103578711
TCA: 656348(Wg)
DPA: 109545715
NVL: 108563674
BMOR: 692745(WNT-1)
BMAN: 114248784
PMAC: 106714251
PRAP: 110994216
HAW: 110371067
TNL: 113501240
PXY: 105397911
API: 100162071
RMD: 113559153
BTAB: 109044616
CLEC: 106666761
ZNE: 110828860
FCD: 110847603
DPX: DAPPUDRAFT_290640(WNT1)
PVM: 113812191
DPTE: 113795867
PTEP: 107438386
PCAN: 112559573
CRG: 105348242
MYI: 110462039
OBI: 106878311(Wnt1)
SHX: MS3_01154
EGL: EGR_10512
NVE: 5521717
EPA: 110232330
ADF: 107333378
AMIL: 114957170
PDAM: 113671498
SPIS: 111330935
DGT: 114517558
HMG: 100204240(hywnt1)
 » show all
Reference
  Authors
Lekven AC, Buckles GR, Kostakis N, Moon RT
  Title
Wnt1 and wnt10b function redundantly at the zebrafish midbrain-hindbrain boundary.
  Journal
Dev Biol 254:172-87 (2003)
DOI:10.1016/S0012-1606(02)00044-1
  Sequence
[dre:30128]
Reference
PMID:2998762
  Authors
van Ooyen A, Kwee V, Nusse R
  Title
The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences.
  Journal
EMBO J 4:2905-9 (1985)
DOI:10.1002/j.1460-2075.1985.tb04021.x
  Sequence
[hsa:7471]
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