KEGG   ORTHOLOGY: K00510
Entry
K00510                      KO                                     

Name
HMOX1
Definition
heme oxygenase 1 [EC:1.14.14.18]
Pathway
map00860  Porphyrin and chlorophyll metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map04066  HIF-1 signaling pathway
map04216  Ferroptosis
map04978  Mineral absorption
map05200  Pathways in cancer
map05206  MicroRNAs in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05225  Hepatocellular carcinoma
map05418  Fluid shear stress and atherosclerosis
Disease
H01714  Chronic obstructive pulmonary disease (COPD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin and chlorophyll metabolism
    K00510  HMOX1; heme oxygenase 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    K00510  HMOX1; heme oxygenase 1
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K00510  HMOX1; heme oxygenase 1
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    K00510  HMOX1; heme oxygenase 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00510  HMOX1; heme oxygenase 1
   05206 MicroRNAs in cancer
    K00510  HMOX1; heme oxygenase 1
   05208 Chemical carcinogenesis - reactive oxygen species
    K00510  HMOX1; heme oxygenase 1
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K00510  HMOX1; heme oxygenase 1
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K00510  HMOX1; heme oxygenase 1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.18  heme oxygenase (biliverdin-producing)
     K00510  HMOX1; heme oxygenase 1
Other DBs
RN: R00311
GO: 0004392
Genes
HSA: 3162(HMOX1)
PTR: 470195(HMOX1)
PPS: 100977821(HMOX1)
GGO: 101152785(HMOX1)
PON: 100173339(HMOX1)
NLE: 100587046(HMOX1)
MCC: 719266(HMOX1)
MCF: 101926565(HMOX1)
CSAB: 103223230(HMOX1)
CATY: 105575783(HMOX1)
PANU: 100999853(HMOX1)
RRO: 104682468(HMOX1) 115895303
RBB: 108540867(HMOX1)
TFN: 117095936(HMOX1)
PTEH: 111549064(HMOX1)
CJC: 100405992 100414343(HMOX1)
SBQ: 101039608(HMOX1)
MMUR: 105883699(HMOX1)
MMU: 15368(Hmox1)
MCAL: 110300233(Hmox1)
MPAH: 110336229(Hmox1)
RNO: 24451(Hmox1)
MCOC: 116069585(Hmox1)
MUN: 110560720(Hmox1)
CGE: 100756872(Hmox1)
PLEU: 114681400(Hmox1)
NGI: 103742105(Hmox1)
HGL: 101708868(Hmox1)
CCAN: 109692950(Hmox1)
OCU: 100008919(HMOX1)
TUP: 102485781(HMOX1)
CFA: 442987(HMOX1)
VVP: 112929075(HMOX1)
VLG: 121492112(HMOX1)
AML: 100479189(HMOX1)
UMR: 103676557(HMOX1)
UAH: 113256008(HMOX1)
ORO: 101364369(HMOX1)
ELK: 111157602
MPUF: 101685452(HMOX1)
EJU: 114197513(HMOX1)
MLX: 117998752(HMOX1)
FCA: 101092621(HMOX1)
PTG: 102948800(HMOX1)
PPAD: 109265494(HMOX1)
AJU: 106981079(HMOX1)
HHV: 120230746(HMOX1)
BTA: 513221(HMOX1)
BOM: 102281265(HMOX1)
BIU: 109559493(HMOX1)
BBUB: 102414425(HMOX1)
CHX: 100860951(HMOX1)
OAS: 101120910(HMOX1)
ODA: 120858594(HMOX1)
SSC: 445512(HMOX1)
CFR: 102505023(HMOX1)
CDK: 105097386(HMOX1)
BACU: 103018426(HMOX1)
LVE: 103077914(HMOX1)
OOR: 101282134(HMOX1)
DLE: 111187883(HMOX1)
PCAD: 102976084(HMOX1)
ECB: 100069058(HMOX1)
EPZ: 103543240(HMOX1)
EAI: 106825719(HMOX1)
MYB: 102248030(HMOX1)
MYD: 102767690(HMOX1)
MMYO: 118650992(HMOX1)
MNA: 107545379(HMOX1)
HAI: 109377639(HMOX1)
DRO: 112321737(HMOX1)
SHON: 119002348(HMOX1)
AJM: 119060410(HMOX1)
MMF: 118624557(HMOX1)
PALE: 102880347(HMOX1)
RAY: 107519297(HMOX1)
MJV: 108401565(HMOX1)
TOD: 119247312(HMOX1) 119253822
LAV: 100673521(HMOX1)
TMU: 101351050
MDO: 100024355(HMOX1) 100030714
SHR: 100925365(HMOX1)
PCW: 110205714(HMOX1)
OAA: 107547784(HMOX1)
GGA: 396287(HMOX1)
PCOC: 116233287(HMOX1)
MGP: 100551243(HMOX1)
CJO: 107314345(HMOX1)
NMEL: 110393409(HMOX1)
APLA: 101805057(HMOX1)
ACYG: 106035937(HMOX1)
TGU: 100226348(HMOX1)
LSR: 110483841(HMOX1)
SCAN: 103813211(HMOX1)
PMOA: 120510044(HMOX1)
GFR: 102043181(HMOX1)
FAB: 101817317(HMOX1)
PHI: 102101610(HMOX1)
PMAJ: 107205203(HMOX1)
CCAE: 111935629(HMOX1)
CCW: 104696269(HMOX1)
ETL: 114055441(HMOX1)
FPG: 101915244(HMOX1)
FCH: 102055466(HMOX1)
CLV: 102084894(HMOX1)
EGZ: 104134285(HMOX1)
NNI: 104021567(HMOX1)
ACUN: 113491611(HMOX1)
PADL: 103924129(HMOX1)
AAM: 106488415(HMOX1)
ASN: 102373399(HMOX1)
AMJ: 102573866(HMOX1)
CPOO: 109316609(HMOX1)
GGN: 109296079(HMOX1)
PSS: 102462727(HMOX1)
CMY: 102940527(HMOX1)
CPIC: 101950994(HMOX1)
TST: 117881059(HMOX1)
CABI: 116821576(HMOX1)
ACS: 100555210(hmox1)
PVT: 110075944(HMOX1)
PBI: 103065892(HMOX1)
PMUR: 107302627(HMOX1)
TSR: 106538506(HMOX1)
PGUT: 117655382(HMOX1)
PMUA: 114605138(HMOX1)
ZVI: 118091347(HMOX1)
GJA: 107109423(HMOX1)
XLA: 398965(hmox1.S) 734976(hmox1.L)
XTR: 100488303(hmox1)
NPR: 108793696(HMOX1)
DRE: 402970(hmox1b) 791518(hmox1a)
CCAR: 109057953
AMEX: 103022889 103044464(hmox1)
TRU: 101070079(hmox1)
NCC: 104950512
ELY: 117254844 117268891(hmox1a)
PLEP: 121942196 121956113(hmox1a)
SLUC: 116040474 116065467(hmox1a)
ECRA: 117936833 117957948(hmox1a)
GAT: 120825069 120828368(hmox1a)
MSAM: 119883566(hmox1a) 119899208
CUD: 121508506 121529147(hmox1a)
OAU: 116321400 116326933(hmox1a)
OML: 112146994(hmox1a) 112157371
XMA: 102223107 102233187(hmox1)
CVG: 107094640(hmox1) 107095695
CTUL: 119771985(hmox1a) 119788238
NFU: 107376240(hmox1) 107382233
KMR: 108236044(hmox1a) 108244335
ALIM: 106515235 106517871(hmox1)
AOCE: 111575507(hmox1) 111584778
CSEM: 103393699(hmox1)
XGL: 120788210(hmox1a) 120800607
BPEC: 110172090(hmox1) 110172617
ELS: 105012149(hmox) 105013172(hmox1)
SFM: 108939753
PKI: 111833488
PSPA: 121309317(hmox1a)
LCM: 102354266(HMOX1)
CMK: 103189669
RTP: 109926307
MGEN: 117224328
NMEA: 116426858
CGIG: 122396484
OBI: 106879648
 » show all
Reference
  Authors
West AR, Oates PS
  Title
Mechanisms of heme iron absorption: current questions and controversies.
  Journal
World J Gastroenterol 14:4101-10 (2008)
DOI:10.3748/wjg.14.4101
Reference
PMID:3345742
  Authors
Yoshida T, Biro P, Cohen T, Muller RM, Shibahara S
  Title
Human heme oxygenase cDNA and induction of its mRNA by hemin.
  Journal
Eur J Biochem 171:457-61 (1988)
DOI:10.1111/j.1432-1033.1988.tb13811.x
  Sequence
[hsa:3162]
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