KEGG   ORTHOLOGY: K00778Help
Entry
K00778                      KO                                     

Name
SIAT1, ST6GAL1
Definition
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1]
Pathway
ko00510  N-Glycan biosynthesis
ko00514  Other types of O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
   00514 Other types of O-glycan biosynthesis
    K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.1  beta-galactoside alpha-(2,6)-sialyltransferase
     K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
Glycosyltransferases [BR:ko01003]
 Terminal extension
  Sialyltransferase
   K00778  SIAT1, ST6GAL1; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
BRITE hierarchy
Other DBs
RN: R05990 R09298
GO: 0003835
CAZy: GT29
Genes
HSA: 6480(ST6GAL1)
PTR: 460922(ST6GAL1)
PPS: 100969795(ST6GAL1)
GGO: 101142727(ST6GAL1)
PON: 100174088(ST6GAL1)
NLE: 100599869(ST6GAL1)
MCC: 708113(ST6GAL1)
MCF: 102121444(ST6GAL1)
CSAB: 103241877(ST6GAL1)
RRO: 104682948(ST6GAL1)
RBB: 108530462(ST6GAL1)
CJC: 100408699(ST6GAL1)
SBQ: 101032294(ST6GAL1)
MMU: 20440(St6gal1)
MCAL: 110311654(St6gal1)
MPAH: 110329758(St6gal1)
RNO: 25197(St6gal1)
MUN: 110548122(St6gal1)
CGE: 100689389(St6gal1)
NGI: 103750114(St6gal1)
HGL: 101718025(St6gal1)
CCAN: 109691378(St6gal1)
OCU: 100353188(ST6GAL1)
TUP: 102499508(ST6GAL1)
CFA: 478668(ST6GAL1)
VVP: 112912868 112926300(ST6GAL1)
AML: 100481066(ST6GAL1)
UMR: 103676045(ST6GAL1)
UAH: 113253796(ST6GAL1)
ORO: 101377549(ST6GAL1)
ELK: 111148556
FCA: 101097832(ST6GAL1)
PTG: 102956769(ST6GAL1)
PPAD: 109275279(ST6GAL1)
AJU: 106968006(ST6GAL1)
BTA: 282073(ST6GAL1)
BOM: 102273022(ST6GAL1)
BIU: 109556984(ST6GAL1)
BBUB: 102400138(ST6GAL1)
CHX: 100861310(ST6GAL1)
OAS: 100913159(ST6GAL1) 114113140
SSC: 100302026(ST6GAL1)
CFR: 102512873(ST6GAL1)
CDK: 105085840(ST6GAL1)
BACU: 103012200(ST6GAL1)
LVE: 103086030(ST6GAL1)
OOR: 101285111(ST6GAL1)
DLE: 111172829(ST6GAL1)
PCAD: 102992136(ST6GAL1)
ECB: 100059539(ST6GAL1)
EPZ: 103567256(ST6GAL1)
EAI: 106832544(ST6GAL1)
MYB: 102244256(ST6GAL1)
MYD: 102753980(ST6GAL1)
MNA: 107527306(ST6GAL1)
HAI: 109396927(ST6GAL1)
DRO: 112308352(ST6GAL1)
PALE: 102886717(ST6GAL1)
RAY: 107505891(ST6GAL1)
MJV: 108401260(ST6GAL1)
LAV: 100664378(ST6GAL1)
TMU: 101351955
MDO: 100617174(ST6GAL1)
SHR: 100922140(ST6GAL1)
PCW: 110221205(ST6GAL1)
OAA: 100093341(ST6GAL1)
GGA: 396169(ST6GAL1)
MGP: 100548556
CJO: 107317947(ST6GAL1)
NMEL: 110397396(ST6GAL1)
APLA: 101803267(ST6GAL1)
ACYG: 106040277(ST6GAL1)
TGU: 100226346(ST6GAL1)
LSR: 110484834(ST6GAL1)
SCAN: 103815542(ST6GAL1)
GFR: 102042024(ST6GAL1)
FAB: 101820079(ST6GAL1)
PHI: 102107561(ST6GAL1)
PMAJ: 107208898(ST6GAL1)
CCAE: 111933760(ST6GAL1)
CCW: 104693051(ST6GAL1)
ETL: 114057719(ST6GAL1)
FPG: 101924763(ST6GAL1)
FCH: 102058385(ST6GAL1)
CLV: 102097093(ST6GAL1)
EGZ: 104135489(ST6GAL1)
NNI: 104023676(ST6GAL1)
ACUN: 113483390(ST6GAL1)
PADL: 103912776(ST6GAL1)
AAM: 106496189(ST6GAL1)
ASN: 102373489(ST6GAL1)
AMJ: 102575767(ST6GAL1)
PSS: 102446128(ST6GAL1)
CMY: 102941507
CPIC: 101939719 101943605(ST6GAL1)
ACS: 100529109(st6gal1)
PVT: 110088940(ST6GAL1)
PBI: 103061620(ST6GAL1)
PMUR: 107286474
TSR: 106550706(ST6GAL1)
PMUA: 114595050 114597762(ST6GAL1)
GJA: 107110554(ST6GAL1) 107115211
XLA: 108717116(st6gal1.L) 108718183(st6gal1.S)
XTR: 100491268(st6gal1)
NPR: 108785675(ST6GAL1)
DRE: 445376(st6gal1)
SANH: 107667425
CCAR: 109045233
IPU: 108279262
PHYP: 113541806
AMEX: 103030360
EEE: 113576168(st6gal1)
TRU: 445982(st6gal1)
LCO: 104921796
NCC: 104951849(st6gal1)
MZE: 101466910
ONL: 100694560
OLA: 100049380(st6gal1)
CVG: 107090303
ALIM: 106514661
BPEC: 110165642
OTW: 112242968
SFM: 108927597
CMK: 103174913(st6gal1)
RTP: 109918596(st6gal1) 109922745
DME: Dmel_CG4871(SiaT)
DER: 6548509
DSE: Dsec_GM11799(Dsec_ST6Gal)
DSI: Dsimw501_GD24925(Dsim_ST6Gal)
DYA: Dyak_GE11423(Dyak_ST6Gal)
DAN: Dana_GF11909(Dana_ST6Gal)
DSR: 110178056
DPO: Dpse_GA18492(Dpse_ST6Gal)
DPE: 6592954
DMN: 108158215
DWI: 6640266
DGR: Dgri_GH21565(Dgri_ST6Gal)
DMO: Dmoj_GI19537(Dmoj_ST6Gal)
DAZ: 108614840
DNV: 108654327
DHE: 111593949
DVI: Dvir_GJ21108(Dvir_ST6Gal)
MDE: 101891865
LCQ: 111681785
DNX: 107173187
TUT: 107362587
 » show all
TaxonomyKoalaUniProt
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KEGG   ORTHOLOGY: K00779Help
Entry
K00779                      KO                                     

Name
SIAT2, ST6GAL2
Definition
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.99.1]
Pathway
ko00510  N-Glycan biosynthesis
ko00514  Other types of O-glycan biosynthesis
ko01100  Metabolic pathways
Module
M00075  N-glycan biosynthesis, complex type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K00779  SIAT2, ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
   00514 Other types of O-glycan biosynthesis
    K00779  SIAT2, ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00779  SIAT2, ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.1  beta-galactoside alpha-(2,6)-sialyltransferase
     K00779  SIAT2, ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
Glycosyltransferases [BR:ko01003]
 Terminal extension
  Sialyltransferase
   K00779  SIAT2, ST6GAL2; beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
BRITE hierarchy
Other DBs
RN: R06188 R09298
GO: 0003835
CAZy: GT29
Genes
HSA: 84620(ST6GAL2)
PTR: 450198(ST6GAL2)
PPS: 100981465(ST6GAL2)
GGO: 101129847(ST6GAL2)
PON: 100456090(ST6GAL2)
NLE: 100580010(ST6GAL2)
MCC: 713552(ST6GAL2)
MCF: 102142751(ST6GAL2)
CSAB: 103241198(ST6GAL2)
RRO: 104660586(ST6GAL2)
RBB: 108512469(ST6GAL2)
CJC: 100411939(ST6GAL2)
SBQ: 101047107(ST6GAL2)
MMU: 240119(St6gal2)
MCAL: 110284258(St6gal2)
MPAH: 110335627(St6gal2)
RNO: 301155(St6gal2)
MUN: 110560861(St6gal2)
CGE: 100763756(St6gal2)
NGI: 103726632(St6gal2)
HGL: 101722644(St6gal2)
CCAN: 109701499(St6gal2)
OCU: 100358153(ST6GAL2)
TUP: 102500330(ST6GAL2)
CFA: 481315(ST6GAL2)
VVP: 112915370(ST6GAL2)
AML: 100478457(ST6GAL2)
UMR: 103670658(ST6GAL2)
UAH: 113267699(ST6GAL2)
ORO: 101374165(ST6GAL2)
ELK: 111155957
FCA: 101098620(ST6GAL2)
PTG: 102962032(ST6GAL2)
PPAD: 109254527(ST6GAL2)
AJU: 106977960(ST6GAL2)
BTA: 493992(ST6GAL2)
BOM: 102285977(ST6GAL2)
BIU: 109566122(ST6GAL2)
BBUB: 102408407(ST6GAL2)
CHX: 102179776(ST6GAL2)
OAS: 101108300(ST6GAL2)
SSC: 100512775(ST6GAL2)
CFR: 102508797(ST6GAL2)
CDK: 105099139(ST6GAL2)
BACU: 103009068(ST6GAL2)
LVE: 103073782(ST6GAL2)
OOR: 101273721(ST6GAL2)
DLE: 111187445(ST6GAL2)
PCAD: 102984003(ST6GAL2)
ECB: 100062033(ST6GAL2)
EPZ: 103555423(ST6GAL2)
EAI: 106829390(ST6GAL2)
MYB: 102241174(ST6GAL2)
MYD: 102768324(ST6GAL2)
MNA: 107528699(ST6GAL2)
HAI: 109375943(ST6GAL2)
DRO: 112297515(ST6GAL2)
PALE: 102890603(ST6GAL2)
RAY: 107497054(ST6GAL2)
LAV: 100660981(ST6GAL2)
TMU: 101355743
MDO: 100019249(ST6GAL2)
SHR: 100932183(ST6GAL2)
PCW: 110209426(ST6GAL2)
OAA: 100077134(ST6GAL2)
GGA: 403122(ST6GAL2)
MGP: 100545097(ST6GAL2)
CJO: 107306533(ST6GAL2)
NMEL: 110406996(ST6GAL2)
APLA: 101796015(ST6GAL2)
ACYG: 106041658(ST6GAL2)
TGU: 100230425(ST6GAL2)
LSR: 110478726(ST6GAL2)
SCAN: 103812379(ST6GAL2)
GFR: 102032813 102038321(ST6GAL2)
FAB: 101810086(ST6GAL2)
PHI: 102109099(ST6GAL2)
PMAJ: 107211419(ST6GAL2)
CCAE: 111922685(ST6GAL2)
CCW: 104686087(ST6GAL2)
ETL: 114066979(ST6GAL2)
FPG: 101914140(ST6GAL2)
FCH: 102056735(ST6GAL2)
CLV: 102087342(ST6GAL2)
EGZ: 104126364(ST6GAL2)
NNI: 104019355(ST6GAL2)
ACUN: 113481283(ST6GAL2)
PADL: 103918841(ST6GAL2)
AAM: 106494052(ST6GAL2)
ASN: 102372316(ST6GAL2)
AMJ: 102569903(ST6GAL2)
PSS: 102453477(ST6GAL2)
CMY: 102943395(ST6GAL2)
CPIC: 101950728(ST6GAL2)
ACS: 100529108(st6gal2)
PVT: 110074124(ST6GAL2)
PBI: 103062404(ST6GAL2)
PMUR: 107288840(ST6GAL2)
TSR: 106540309(ST6GAL2) 106545885
PMUA: 114596422(ST6GAL2)
GJA: 107125130(ST6GAL2)
XLA: 108708393(st6gal2.L) 108709694(st6gal2.S)
XTR: 407846(st6gal2)
NPR: 108785132(ST6GAL2)
DRE: 403116(st6gal2a)
IPU: 108266814(st6gal2) 108273345
PHYP: 113525857(st6gal2) 113538434
AMEX: 103024101(st6gal2) 103031874
EEE: 113574044 113584885(st6gal2)
TRU: 777969(st6gal2)
LCO: 104932096(st6gal2) 104934011
NCC: 104957421(st6gal2)
MZE: 101464130(st6gal2)
ONL: 100704184(st6gal2)
OLA: 100049381(st6gal2)
XMA: 102229475(st6gal2) 102231535
XCO: 114148521(st6gal2) 114152599
PRET: 103476390 103480039(st6gal2)
CVG: 107096899(st6gal2)
NFU: 107384328 107389803(st6gal2)
KMR: 108228306 108232466(st6gal2)
ALIM: 106514590 106519824(st6gal2)
AOCE: 111563401(st6gal1) 111570337 111582969(st6gal2)
CSEM: 103391691(st6gal2)
POV: 109631344(st6gal2)
LCF: 108881134 108901078(st6gal2)
SDU: 111218195(st6gal2)
SLAL: 111646873 111662108(st6gal2)
HCQ: 109530661(st6gal2)
BPEC: 110173121(st6gal2)
MALB: 109965389(st6gal2)
SFM: 108920576 108933083(st6gal2)
PKI: 111833845(st6gal2) 111843653
LCM: 102359235(ST6GAL2)
CMK: 103172241(st6gal2)
HAW: 110369814
TNL: 113492654
PXY: 105396375
CSCU: 111636481
PTEP: 107450093
 » show all
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KEGG   ORTHOLOGY: K00781Help
Entry
K00781                      KO                                     

Name
SIAT6
Definition
neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6]
Pathway
ko00513  Various types of N-glycan biosynthesis
ko00514  Other types of O-glycan biosynthesis
ko00515  Mannose type O-glycan biosynthesis
ko00533  Glycosaminoglycan biosynthesis - keratan sulfate
ko00601  Glycosphingolipid biosynthesis - lacto and neolacto series
ko01100  Metabolic pathways
Disease
H00606  Early infantile epileptic encephalopathy
H00768  Autosomal recessive mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00513 Various types of N-glycan biosynthesis
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
   00515 Mannose type O-glycan biosynthesis
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
   00514 Other types of O-glycan biosynthesis
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
   00533 Glycosaminoglycan biosynthesis - keratan sulfate
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
   00601 Glycosphingolipid biosynthesis - lacto and neolacto series
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.6  N-acetyllactosaminide alpha-2,3-sialyltransferase
     K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
Glycosyltransferases [BR:ko01003]
 Terminal extension
  Sialyltransferase
   K00781  SIAT6; neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
BRITE hierarchy
Other DBs
RN: R06153 R09297
GO: 0008118
CAZy: GT29
Genes
HSA: 6487(ST3GAL3)
PTR: 456832(ST3GAL3)
PPS: 100982060(ST3GAL3)
GGO: 101126091(ST3GAL3)
PON: 100441500(ST3GAL3)
NLE: 100596717(ST3GAL3)
MCC: 703599(ST3GAL3)
MCF: 102124772(ST3GAL3)
CSAB: 103224957(ST3GAL3)
RRO: 104669039(ST3GAL3)
RBB: 108535692(ST3GAL3)
CJC: 100411797(ST3GAL3)
SBQ: 101041573(ST3GAL3)
MMU: 20441(St3gal3)
MCAL: 110293535(St3gal3)
MPAH: 110323790(St3gal3)
RNO: 64445(St3gal3)
MUN: 110552921(St3gal3)
CGE: 100689187(St3gal3)
NGI: 103743864(St3gal3)
HGL: 101716398(St3gal3)
CCAN: 109681562 109681564(St3gal3)
OCU: 100353106(ST3GAL3)
TUP: 102486753(ST3GAL3)
CFA: 610736(ST3GAL3)
VVP: 112914822(ST3GAL3)
AML: 100472631(ST3GAL3)
UMR: 103670807(ST3GAL3)
UAH: 113254779(ST3GAL3)
ORO: 101366681(ST3GAL3)
ELK: 111142879
FCA: 101081911(ST3GAL3)
PTG: 102966623(ST3GAL3)
PPAD: 109254792(ST3GAL3)
AJU: 106970220(ST3GAL3)
BTA: 444859(ST3GAL3)
BOM: 102284552(ST3GAL3)
BIU: 109556395(ST3GAL3)
BBUB: 102394821(ST3GAL3)
CHX: 102168794(ST3GAL3)
OAS: 101112269(ST3GAL3)
SSC: 396619(ST3GAL3)
CFR: 102517093(ST3GAL3)
CDK: 105090902(ST3GAL3)
BACU: 103003034(ST3GAL3)
LVE: 103083644(ST3GAL3)
OOR: 101287105(ST3GAL3)
DLE: 111175708(ST3GAL3)
PCAD: 102989838(ST3GAL3)
ECB: 100053104(ST3GAL3)
EPZ: 103567339
EAI: 106847915(ST3GAL3)
MYB: 102245915(ST3GAL3)
MYD: 102773348(ST3GAL3)
MNA: 107526698(ST3GAL3)
HAI: 109383404(ST3GAL3)
DRO: 112314533(ST3GAL3)
PALE: 102883140(ST3GAL3)
RAY: 107499497(ST3GAL3)
MJV: 108401720 108404460(ST3GAL3)
LAV: 100668469(ST3GAL3)
TMU: 101360821
MDO: 100025401(ST3GAL3)
SHR: 100917951(ST3GAL3)
PCW: 110200182(ST3GAL3)
OAA: 100078221(ST3GAL3)
GGA: 424572(ST3GAL3)
MGP: 100543009
CJO: 107317545(ST3GAL3)
NMEL: 110402236(ST3GAL3)
APLA: 101804175(ST3GAL3)
ACYG: 106033989(ST3GAL3)
TGU: 100221242(ST3GAL3)
LSR: 110469436(ST3GAL3)
SCAN: 103814959(ST3GAL3)
GFR: 102034732(ST3GAL3)
FAB: 101807588(ST3GAL3)
PHI: 102104267(ST3GAL3)
PMAJ: 107208043(ST3GAL3)
CCAE: 111933145(ST3GAL3)
CCW: 104695266(ST3GAL3)
ETL: 114061767(ST3GAL3)
FPG: 101917466(ST3GAL3)
FCH: 102055195(ST3GAL3)
CLV: 102089431(ST3GAL3)
EGZ: 104125511(ST3GAL3)
NNI: 104015432(ST3GAL3)
ACUN: 113482641(ST3GAL3)
PADL: 103924072(ST3GAL3)
AAM: 106484925(ST3GAL3)
ASN: 102387225(ST3GAL3)
AMJ: 102570899(ST3GAL3)
PSS: 102458402(ST3GAL3)
CMY: 102937505(ST3GAL3)
CPIC: 101943704(ST3GAL3)
ACS: 100556902(st3gal3)
PVT: 110073793(ST3GAL3)
PBI: 103048808(ST3GAL3)
PMUR: 107283445(ST3GAL3)
TSR: 106539862(ST3GAL3) 106553194
PMUA: 114599128(ST3GAL3)
GJA: 107120284(ST3GAL3)
XLA: 100462908(st3gal-iii) 108715547(st3Gal-III) 398746(st3gal3.S)
XTR: 402789(st3gal3)
NPR: 108789048(ST3GAL3)
DRE: 407659(st3gal3b)
IPU: 108271839(st3gal3) 108280530
PHYP: 113526502(st3gal3) 113546447
AMEX: 103026988(st3gal3) 103044556
EEE: 113586631 113591701(st3gal3)
TRU: 445973(st3gal3)
LCO: 104920950 104940288(st3gal3)
NCC: 104948573 104964780(st3gal3)
MZE: 101484929(st3gal3)
ONL: 100697741(st3gal3)
OLA: 100049527(st3gal3)
XMA: 102237009(st3gal3)
XCO: 114146435(st3gal3)
PRET: 103479140(st3gal3)
CVG: 107104529 107105033(st3gal3)
NFU: 107397021(st3gal3)
KMR: 108244505(st3gal3)
ALIM: 106531421(st3gal3)
CSEM: 103395857 103399833(st3gal3)
HCQ: 109518900(st3gal3)
BPEC: 110174824(st3gal3)
MALB: 109969271(st3gal3)
SFM: 108923813(st3gal3)
PKI: 111846033(st3gal3)
LCM: 102351151(ST3GAL3)
CMK: 103174609(st3gal3)
RTP: 109913946(st3gal3)
SPU: 100893566
APLC: 110982962
 » show all
TaxonomyKoalaUniProt
LinkDB All DBs

KEGG   ENZYME: 2.4.99.6Help
Entry
EC 2.4.99.6                 Enzyme                                 

Name
N-acetyllactosaminide alpha-2,3-sialyltransferase;
cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase;
alpha2->3 sialyltransferase (ambiguous);
SiaT (ambiguous);
CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase;
neolactotetraosylceramide alpha-2,3-sialyltransferase;
CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein alpha-(2->3)-N-acetylneuraminyltransferase
Class
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
BRITE hierarchy
Sysname
CMP-N-acetyl-beta-neuraminate:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R (2->3)-N-acetyl-alpha-neuraminyltransferase (configuration-inverting)
Reaction(IUBMB)
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R = CMP + N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R [RN:R04596 R09297]
Reaction(KEGG)
R04596 R09297(G);
(other) R04656 R06026(G) R06037(G) R06153(G)
Show
Substrate
CMP-N-acetyl-beta-neuraminate [CPD:C00128];
beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R [CPD:C00694]
Product
CMP [CPD:C00055];
N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-R
Comment
The enzyme recognizes the sequence beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl (known as type 2 histo-blood group precursor disaccharide) in non-reducing termini of glycan moieties in glycoproteins and glycolipids. The enzyme from chicken brain was shown to act on neolactotetraosylceramide, producing ganglioside LM1 [2].
History
EC 2.4.99.6 created 1984, modified 1986 (EC 2.4.99.10 created 1986, incorporated 2017)
Pathway
ec00513  Various types of N-glycan biosynthesis
ec00514  Other types of O-glycan biosynthesis
ec00515  Mannose type O-glycan biosynthesis
ec00533  Glycosaminoglycan biosynthesis - keratan sulfate
ec00601  Glycosphingolipid biosynthesis - lacto and neolacto series
ec01100  Metabolic pathways
Orthology
K00781  neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6)
K03792  neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 10)
Genes
HSA: 10402(ST3GAL6) 6487(ST3GAL3)
PTR: 456832(ST3GAL3) 460547(ST3GAL6)
PPS: 100977718(ST3GAL6) 100982060(ST3GAL3)
GGO: 101126091(ST3GAL3) 101133620(ST3GAL6)
PON: 100171770(ST3GAL6) 100441500(ST3GAL3)
NLE: 100583585(ST3GAL6) 100596717(ST3GAL3)
MCC: 699096(ST3GAL6) 703599(ST3GAL3)
MCF: 102115716(ST3GAL6) 102124772(ST3GAL3)
CSAB: 103224957(ST3GAL3) 103228470(ST3GAL6)
RRO: 104654524(ST3GAL6) 104669039(ST3GAL3)
RBB: 108516678(ST3GAL6) 108535692(ST3GAL3)
CJC: 100389235(ST3GAL6) 100411797(ST3GAL3)
SBQ: 101030408 101041573(ST3GAL3)
MMU: 20441(St3gal3) 54613(St3gal6)
MCAL: 110293535(St3gal3) 110311509(St3gal6)
MPAH: 110323790(St3gal3) 110329727(St3gal6)
RNO: 304023(St3gal6) 64445(St3gal3)
MUN: 110552921(St3gal3) 110564564(St3gal6)
CGE: 100689187(St3gal3) 100771326(St3gal6)
NGI: 103732633(St3gal6) 103743864(St3gal3)
HGL: 101706310(St3gal6) 101716398(St3gal3)
CCAN: 109681562 109681564(St3gal3) 109696030(St3gal6)
OCU: 100339165(ST3GAL6) 100353106(ST3GAL3)
TUP: 102481523(ST3GAL6) 102486753(ST3GAL3)
CFA: 478535(ST3GAL6) 610736(ST3GAL3)
VVP: 112913373(ST3GAL6) 112914822(ST3GAL3)
AML: 100472631(ST3GAL3) 100481119(ST3GAL6)
UMR: 103670807(ST3GAL3) 103673244(ST3GAL6)
UAH: 113250428(ST3GAL6) 113254779(ST3GAL3)
ORO: 101366681(ST3GAL3) 101383996(ST3GAL6)
FCA: 101081911(ST3GAL3) 101091552(ST3GAL6)
PTG: 102952023(ST3GAL6) 102966623(ST3GAL3)
PPAD: 109254792(ST3GAL3) 109266303(ST3GAL6)
AJU: 106970220(ST3GAL3) 106982524(ST3GAL6)
BTA: 444859(ST3GAL3) 444860(ST3GAL6)
BOM: 102265994(ST3GAL6) 102284552(ST3GAL3)
BIU: 109556395(ST3GAL3) 109564929(ST3GAL6)
BBUB: 102394821(ST3GAL3) 102399293(ST3GAL6)
CHX: 102168794(ST3GAL3) 102175162(ST3GAL6)
OAS: 101106812(ST3GAL6) 101112269(ST3GAL3)
SSC: 100739492(ST3GAL6) 396619(ST3GAL3)
CFR: 102516778(ST3GAL6) 102517093(ST3GAL3)
CDK: 105087739(ST3GAL6) 105090902(ST3GAL3)
BACU: 103001584(ST3GAL6) 103003034(ST3GAL3)
LVE: 103078993(ST3GAL6) 103083644(ST3GAL3)
OOR: 101286804(ST3GAL6) 101287105(ST3GAL3)
DLE: 111175708(ST3GAL3) 111180240(ST3GAL6)
PCAD: 102986979(ST3GAL6) 102989838(ST3GAL3)
ECB: 100053104(ST3GAL3) 100062218(ST3GAL6)
EPZ: 103561946(ST3GAL6) 103567339
EAI: 106824252(ST3GAL6) 106847915(ST3GAL3)
MYB: 102245915(ST3GAL3) 102260204(ST3GAL6)
MYD: 102754272(ST3GAL6) 102773348(ST3GAL3)
MNA: 107526698(ST3GAL3) 107527090(ST3GAL6)
HAI: 109377051(ST3GAL6) 109383404(ST3GAL3)
DRO: 112302602(ST3GAL6) 112314533(ST3GAL3)
PALE: 102883140(ST3GAL3) 102889744(ST3GAL6)
RAY: 107499497(ST3GAL3) 107505578(ST3GAL6)
MJV: 108383486(ST3GAL6) 108401720 108404460(ST3GAL3)
LAV: 100668469(ST3GAL3) 100672752(ST3GAL6)
MDO: 100017812(ST3GAL6) 100025401(ST3GAL3)
SHR: 100917951(ST3GAL3) 100923762(ST3GAL6)
PCW: 110200182(ST3GAL3) 110202307(ST3GAL6)
OAA: 100078221(ST3GAL3) 100681144(ST3GAL6)
GGA: 395138(ST3GAL6) 424572(ST3GAL3)
MGP: 100541741(ST3GAL6) 100543009
CJO: 107317545(ST3GAL3) 107320596(ST3GAL6)
NMEL: 110400054(ST3GAL6) 110402236(ST3GAL3)
APLA: 101802079(ST3GAL6) 101804175(ST3GAL3)
ACYG: 106033989(ST3GAL3) 106038338(ST3GAL6)
TGU: 100221242(ST3GAL3) 100222736(ST3GAL6)
LSR: 110469436(ST3GAL3) 110480715(ST3GAL6)
SCAN: 103814959(ST3GAL3) 103827065(ST3GAL6)
GFR: 102034732(ST3GAL3) 102043783(ST3GAL6)
FAB: 101807588(ST3GAL3) 101815960(ST3GAL6)
PHI: 102099818(ST3GAL6) 102104267(ST3GAL3)
PMAJ: 107208043(ST3GAL3) 107210567(ST3GAL6)
CCAE: 111933145(ST3GAL3) 111939731(ST3GAL6)
CCW: 104687090(ST3GAL6) 104695266(ST3GAL3)
ETL: 114061767(ST3GAL3) 114068360(ST3GAL6)
FPG: 101915399(ST3GAL6) 101917466(ST3GAL3)
FCH: 102055195(ST3GAL3) 102060181(ST3GAL6)
CLV: 102083691(ST3GAL6) 102089431(ST3GAL3)
EGZ: 104125511(ST3GAL3) 104126021(ST3GAL6)
NNI: 104014095(ST3GAL6) 104015432(ST3GAL3)
ACUN: 113482641(ST3GAL3) 113491567(ST3GAL6)
PADL: 103921709(ST3GAL6) 103924072(ST3GAL3)
AAM: 106484925(ST3GAL3) 106490642(ST3GAL6)
ASN: 102377903(ST3GAL6) 102387225(ST3GAL3)
AMJ: 102570018(ST3GAL6) 102570899(ST3GAL3)
PSS: 102458402(ST3GAL3) 102462369(ST3GAL6)
CMY: 102937505(ST3GAL3) 102947450(ST3GAL6)
CPIC: 101932642(ST3GAL6) 101943704(ST3GAL3)
ACS: 100556902(st3gal3) 100557291(st3gal6)
PVT: 110073793(ST3GAL3) 110074621(ST3GAL6)
PBI: 103048808(ST3GAL3) 103051166(ST3GAL6)
PMUR: 107283445(ST3GAL3) 107291773(ST3GAL6)
TSR: 106539862(ST3GAL3) 106553194 106554512(ST3GAL6)
PMUA: 114595865(ST3GAL6) 114599128(ST3GAL3)
GJA: 107110020(ST3GAL6) 107120284(ST3GAL3)
XLA: 100462908(st3gal-iii) 108709199 108715547(st3Gal-III) 398745(st3gal6.L) 398746(st3gal3.S)
XTR: 402789(st3gal3) 402790(st3gal6)
DRE: 407659(st3gal3b)
IPU: 108271839(st3gal3) 108280530
PHYP: 113526502(st3gal3) 113546447
AMEX: 103026988(st3gal3) 103044556
EEE: 113586631 113591701(st3gal3)
TRU: 445973(st3gal3)
LCO: 104920950 104940288(st3gal3)
NCC: 104948573 104964780(st3gal3)
MZE: 101484929(st3gal3)
ONL: 100697741(st3gal3)
OLA: 100049527(st3gal3)
XMA: 102237009(st3gal3)
XCO: 114146435(st3gal3)
PRET: 103479140(st3gal3)
CVG: 107104529 107105033(st3gal3)
NFU: 107397021(st3gal3)
KMR: 108244505(st3gal3)
ALIM: 106531421(st3gal3)
CSEM: 103395857 103399833(st3gal3)
HCQ: 109518900(st3gal3)
BPEC: 110174824(st3gal3)
MALB: 109969271(st3gal3)
SFM: 108923813(st3gal3)
PKI: 111846033(st3gal3)
LCM: 102351151(ST3GAL3) 102356485(ST3GAL6)
CMK: 103174609(st3gal3) 103180110(st3gal6)
RTP: 109911662(st3gal6) 109913946(st3gal3)
APLC: 110982962
 » show all
Taxonomy
Reference
1  [PMID:7204397]
  Authors
Van den Eijnden DH, Schiphorst WE.
  Title
Detection of beta-galactosyl(1 leads to 4)N-acetylglucosaminide alpha(2 leads to 3)-sialyltransferase activity in fetal calf liver and other tissues.
  Journal
J Biol Chem 256:3159-62 (1981)
Reference
2  [PMID:7130178]
  Authors
Basu M, Basu S, Stoffyn A, Stoffyn P.
  Title
Biosynthesis in vitro of sialyl(alpha 2-3)neolactotetraosylceramide by a sialyltransferase from embryonic chicken brain.
  Journal
J Biol Chem 257:12765-9 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.99.6
IUBMB Enzyme Nomenclature: 2.4.99.6
ExPASy - ENZYME nomenclature database: 2.4.99.6
BRENDA, the Enzyme Database: 2.4.99.6
CAS: 77537-85-0
LinkDB All DBs

KEGG   ENZYME: 2.4.99.1Help
Entry
EC 2.4.99.1                 Enzyme                                 

Name
beta-galactoside alpha-(2,6)-sialyltransferase;
ST6Gal-I;
CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase;
lactosylceramide alpha-2,6-N-sialyltransferase;
CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine alpha-(2->6)-N-acetylneuraminyltransferase;
beta-galactoside alpha-2,6-sialyltransferase
Class
Transferases;
Glycosyltransferases;
Transferring other glycosyl groups
BRITE hierarchy
Sysname
CMP-N-acetyl-beta-neuraminate:beta-D-galactoside alpha-(2->6)-N-acetylneuraminyltransferase (configuration-inverting)
Reaction(IUBMB)
CMP-N-acetyl-beta-neuraminate + beta-D-galactosyl-R = CMP + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R [RN:R04532 R06188]
Reaction(KEGG)
R04532 R06188(G);
(other) R03489 R05580 R05905(G) R05906(G) R05990(G) R06121(G) R09298(G)
Show
Substrate
CMP-N-acetyl-beta-neuraminate [CPD:C00128];
beta-D-galactosyl-R [CPD:C02900]
Product
CMP [CPD:C00055];
N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-R
Comment
The enzyme acts on the terminal non-reducing beta-D-galactosyl residue of the oligosaccharide moiety of glycoproteins and glycolipids.
History
EC 2.4.99.1 created 1972, modified 1976, modified 1986, modified 2016 (EC 2.4.99.11 created 1992, incorporated 2016), modified 2017
Pathway
ec00510  N-Glycan biosynthesis
ec00514  Other types of O-glycan biosynthesis
ec01100  Metabolic pathways
Orthology
K00778  beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1)
K00779  beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2)
K12248  beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 0160)
Genes
HSA: 6480(ST6GAL1) 84620(ST6GAL2)
PTR: 450198(ST6GAL2) 460922(ST6GAL1)
PPS: 100969795(ST6GAL1) 100981465(ST6GAL2)
GGO: 101129847(ST6GAL2) 101142727(ST6GAL1)
PON: 100174088(ST6GAL1) 100456090(ST6GAL2)
NLE: 100580010(ST6GAL2) 100599869(ST6GAL1)
MCC: 708113(ST6GAL1) 713552(ST6GAL2)
MCF: 102121444(ST6GAL1) 102142751(ST6GAL2)
CSAB: 103241198(ST6GAL2) 103241877(ST6GAL1)
RRO: 104660586(ST6GAL2) 104682948(ST6GAL1)
RBB: 108512469(ST6GAL2) 108530462(ST6GAL1)
CJC: 100408699(ST6GAL1) 100411939(ST6GAL2)
SBQ: 101032294(ST6GAL1) 101047107(ST6GAL2)
MMU: 20440(St6gal1) 240119(St6gal2)
MCAL: 110284258(St6gal2) 110311654(St6gal1)
MPAH: 110329758(St6gal1) 110335627(St6gal2)
RNO: 25197(St6gal1) 301155(St6gal2)
MUN: 110548122(St6gal1) 110560861(St6gal2)
CGE: 100689389(St6gal1) 100763756(St6gal2)
NGI: 103726632(St6gal2) 103750114(St6gal1)
HGL: 101718025(St6gal1) 101722644(St6gal2)
CCAN: 109691378(St6gal1) 109701499(St6gal2)
OCU: 100353188(ST6GAL1) 100358153(ST6GAL2)
TUP: 102499508(ST6GAL1) 102500330(ST6GAL2)
CFA: 478668(ST6GAL1) 481315(ST6GAL2)
VVP: 112912868 112915370(ST6GAL2) 112926300(ST6GAL1)
AML: 100478457(ST6GAL2) 100481066(ST6GAL1)
UMR: 103670658(ST6GAL2) 103676045(ST6GAL1)
UAH: 113253796(ST6GAL1) 113267699(ST6GAL2)
ORO: 101374165(ST6GAL2) 101377549(ST6GAL1)
FCA: 101097832(ST6GAL1) 101098620(ST6GAL2)
PTG: 102956769(ST6GAL1) 102962032(ST6GAL2)
PPAD: 109254527(ST6GAL2) 109275279(ST6GAL1)
AJU: 106968006(ST6GAL1) 106977960(ST6GAL2)
BTA: 282073(ST6GAL1) 493992(ST6GAL2)
BOM: 102273022(ST6GAL1) 102285977(ST6GAL2)
BIU: 109556984(ST6GAL1) 109566122(ST6GAL2)
BBUB: 102400138(ST6GAL1) 102408407(ST6GAL2)
CHX: 100861310(ST6GAL1) 102179776(ST6GAL2)
OAS: 100913159(ST6GAL1) 101108300(ST6GAL2) 114113140
SSC: 100302026(ST6GAL1) 100512775(ST6GAL2)
CFR: 102508797(ST6GAL2) 102512873(ST6GAL1)
CDK: 105085840(ST6GAL1) 105099139(ST6GAL2)
BACU: 103009068(ST6GAL2) 103012200(ST6GAL1)
LVE: 103073782(ST6GAL2) 103086030(ST6GAL1)
OOR: 101273721(ST6GAL2) 101285111(ST6GAL1)
DLE: 111172829(ST6GAL1) 111187445(ST6GAL2)
PCAD: 102984003(ST6GAL2) 102992136(ST6GAL1)
ECB: 100059539(ST6GAL1) 100062033(ST6GAL2)
EPZ: 103555423(ST6GAL2) 103567256(ST6GAL1)
EAI: 106829390(ST6GAL2) 106832544(ST6GAL1)
MYB: 102241174(ST6GAL2) 102244256(ST6GAL1)
MYD: 102753980(ST6GAL1) 102768324(ST6GAL2)
MNA: 107527306(ST6GAL1) 107528699(ST6GAL2)
HAI: 109375943(ST6GAL2) 109396927(ST6GAL1)
DRO: 112297515(ST6GAL2) 112308352(ST6GAL1)
PALE: 102886717(ST6GAL1) 102890603(ST6GAL2)
RAY: 107497054(ST6GAL2) 107505891(ST6GAL1)
LAV: 100660981(ST6GAL2) 100664378(ST6GAL1)
MDO: 100019249(ST6GAL2) 100617174(ST6GAL1)
SHR: 100922140(ST6GAL1) 100932183(ST6GAL2)
PCW: 110209426(ST6GAL2) 110221205(ST6GAL1)
OAA: 100077134(ST6GAL2) 100093341(ST6GAL1)
GGA: 396169(ST6GAL1) 403122(ST6GAL2)
MGP: 100545097(ST6GAL2) 100548556
CJO: 107306533(ST6GAL2) 107317947(ST6GAL1)
NMEL: 110397396(ST6GAL1) 110406996(ST6GAL2)
APLA: 101796015(ST6GAL2) 101803267(ST6GAL1)
ACYG: 106040277(ST6GAL1) 106041658(ST6GAL2)
TGU: 100226346(ST6GAL1) 100230425(ST6GAL2)
LSR: 110478726(ST6GAL2) 110484834(ST6GAL1)
SCAN: 103812379(ST6GAL2) 103815542(ST6GAL1)
GFR: 102032813 102038321(ST6GAL2) 102042024(ST6GAL1)
FAB: 101810086(ST6GAL2) 101820079(ST6GAL1)
PHI: 102107561(ST6GAL1) 102109099(ST6GAL2)
PMAJ: 107208898(ST6GAL1) 107211419(ST6GAL2)
CCAE: 111922685(ST6GAL2) 111933760(ST6GAL1)
CCW: 104686087(ST6GAL2) 104693051(ST6GAL1)
ETL: 114057719(ST6GAL1) 114066979(ST6GAL2)
FPG: 101914140(ST6GAL2) 101924763(ST6GAL1)
FCH: 102056735(ST6GAL2) 102058385(ST6GAL1)
CLV: 102087342(ST6GAL2) 102097093(ST6GAL1)
EGZ: 104126364(ST6GAL2) 104135489(ST6GAL1)
NNI: 104019355(ST6GAL2) 104023676(ST6GAL1)
ACUN: 113481283(ST6GAL2) 113483390(ST6GAL1)
PADL: 103912776(ST6GAL1) 103918841(ST6GAL2)
AAM: 106494052(ST6GAL2) 106496189(ST6GAL1)
ASN: 102372316(ST6GAL2) 102373489(ST6GAL1)
AMJ: 102569903(ST6GAL2) 102575767(ST6GAL1)
PSS: 102446128(ST6GAL1) 102453477(ST6GAL2)
CMY: 102941507 102943395(ST6GAL2)
CPIC: 101939719 101943605(ST6GAL1) 101950728(ST6GAL2)
ACS: 100529108(st6gal2) 100529109(st6gal1)
PVT: 110074124(ST6GAL2) 110088940(ST6GAL1)
PBI: 103061620(ST6GAL1) 103062404(ST6GAL2)
PMUR: 107286474 107288840(ST6GAL2)
TSR: 106540309(ST6GAL2) 106545885 106550706(ST6GAL1)
PMUA: 114595050 114596422(ST6GAL2) 114597762(ST6GAL1)
GJA: 107110554(ST6GAL1) 107115211 107125130(ST6GAL2)
XLA: 108708393(st6gal2.L) 108709694(st6gal2.S) 108717116(st6gal1.L) 108718183(st6gal1.S)
XTR: 100491268(st6gal1) 407846(st6gal2)
NPR: 108785132(ST6GAL2) 108785675(ST6GAL1)
DRE: 403116(st6gal2a) 445376(st6gal1)
PHYP: 113525857(st6gal2) 113538434 113541806
AMEX: 103024101(st6gal2) 103030360 103031874
EEE: 113574044 113576168(st6gal1) 113584885(st6gal2)
TRU: 445982(st6gal1) 777969(st6gal2)
NCC: 104951849(st6gal1) 104957421(st6gal2)
MZE: 101464130(st6gal2) 101466910
ONL: 100694560 100704184(st6gal2)
OLA: 100049380(st6gal1) 100049381(st6gal2)
XMA: 102229475(st6gal2) 102231535
XCO: 114148521(st6gal2) 114152599
PRET: 103476390 103480039(st6gal2)
CVG: 107090303 107096899(st6gal2)
NFU: 107384328 107389803(st6gal2)
ALIM: 106514590 106514661 106519824(st6gal2)
AOCE: 111563401(st6gal1) 111570337 111582969(st6gal2)
CSEM: 103391691(st6gal2)
POV: 109631344(st6gal2)
LCF: 108881134 108901078(st6gal2)
SDU: 111218195(st6gal2)
SLAL: 111646873 111662108(st6gal2)
HCQ: 109530661(st6gal2)
BPEC: 110165642 110173121(st6gal2)
MALB: 109965389(st6gal2)
LCM: 102351140(ST6GAL1) 102359235(ST6GAL2) 102360214 102360354
CMK: 103172241(st6gal2) 103174913(st6gal1)
DME: Dmel_CG4871(SiaT)
DER: 6548509
DSE: Dsec_GM11799(Dsec_ST6Gal)
DSI: Dsimw501_GD24925(Dsim_ST6Gal)
DYA: Dyak_GE11423(Dyak_ST6Gal)
DAN: Dana_GF11909(Dana_ST6Gal)
DSR: 110178056
DPO: Dpse_GA18492(Dpse_ST6Gal)
DPE: 6592954
DMN: 108158215
DWI: 6640266
DGR: Dgri_GH21565(Dgri_ST6Gal)
DMO: Dmoj_GI19537(Dmoj_ST6Gal)
DAZ: 108614840
DNV: 108654327
DHE: 111593949
DVI: Dvir_GJ21108(Dvir_ST6Gal)
MDE: 101891865
LCQ: 111681785
HAW: 110369814
TNL: 113492654
PXY: 105396375
DNX: 107173187
TUT: 107362587
CSCU: 111636481
PTEP: 107450093
HDU: HD_0053
PMU: PM0188
PMP: Pmu_11250
PMUL: DR93_1878
SWP: swp_5060
 » show all
Taxonomy
Reference
1  [PMID:5726897]
  Authors
Spiro MJ, Spiro RG.
  Title
Glycoprotein biosynthesis: studies on thyroglobulin. Thyroid sialyltransferase.
  Journal
J Biol Chem 243:6520-8 (1968)
Reference
2  [PMID:4313609]
  Authors
Hickman J, Ashwell G, Morell AG, van den Hamer CJ, Scheinberg IH.
  Title
Physical and chemical studies on ceruloplasmin. 8. Preparation of N-acetylneuraminic acid-1-14C-labeled ceruloplasmin.
  Journal
J Biol Chem 245:759-66 (1970)
Reference
3  [PMID:4723915]
  Authors
Bartholomew BA, Jourdian GW, Roseman S.
  Title
The sialic acids. XV. Transfer of sialic acid to glycoproteins by a sialyltransferase from colostrum.
  Journal
J Biol Chem 248:5751-62 (1973)
Reference
4  [PMID:849932]
  Authors
Paulson JC, Beranek WE, Hill RL.
  Title
Purification of a sialyltransferase from bovine colostrum by affinity chromatography on CDP-agarose.
  Journal
J Biol Chem 252:2356-62 (1977)
Reference
5  [PMID:6366476]
  Authors
Schachter H, Narasimhan S, Gleeson P, Vella G.
  Title
Glycosyltransferases involved in elongation of N-glycosidically linked oligosaccharides of the complex or N-acetyllactosamine type.
  Journal
Methods Enzymol 98:98-134 (1983)
Reference
6  [PMID:2460092]
  Authors
Albarracin I, Lassaga FE, Caputto R.
  Title
Purification and characterization of an endogenous inhibitor of the sialyltransferase CMP-N-acetylneuraminate: lactosylceramide alpha 2,6-N-acetylneuraminyltransferase (EC 2.4.99.-).
  Journal
Biochem J 254:559-65 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 2.4.99.1
IUBMB Enzyme Nomenclature: 2.4.99.1
ExPASy - ENZYME nomenclature database: 2.4.99.1
BRENDA, the Enzyme Database: 2.4.99.1
CAS: 9075-81-4
LinkDB All DBs

KEGG   REACTION: R09297Help
Entry
R09297                      Reaction                               

Name
CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-glycoprotein alpha-(2->3)-N-acetylneuraminyltransferase
Definition
CMP-N-acetylneuraminate + G13054 <=> CMP + G05914
Equation
Enzyme
Pathway
rn00514  Other types of O-glycan biosynthesis
Orthology
K00781  neolactotetraosylceramide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6]
LinkDB All DBs

KEGG   REACTION: R09298Help
Entry
R09298                      Reaction                               

Name
CMP-N-acetylneuraminate:beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine alpha-(2->6)-N-acetylneuraminyltransferase
Definition
CMP-N-acetylneuraminate + G13054 <=> CMP + G10982
Equation
Enzyme
Pathway
rn00514  Other types of O-glycan biosynthesis
Orthology
K00778  beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1]
K00779  beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.99.1]
LinkDB All DBs

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