KEGG   ORTHOLOGY: K00825
Entry
K00825                      KO                                     

Name
AADAT, KAT2
Definition
kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
Pathway
ko00300  Lysine biosynthesis
ko00310  Lysine degradation
ko00380  Tryptophan metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01210  2-Oxocarboxylic acid metabolism
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
   00310 Lysine degradation
    K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
   00380 Tryptophan metabolism
    K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7  kynurenine---oxoglutarate transaminase
     K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
    2.6.1.39  2-aminoadipate transaminase
     K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K00825  AADAT, KAT2; kynurenine/2-aminoadipate aminotransferase
Other DBs
RN: R01939 R01956 R04171
GO: 0016212 0047536
Genes
HSA: 51166(AADAT)
PTR: 461601(AADAT)
PPS: 100995091(AADAT)
GGO: 101151419(AADAT)
PON: 100435746(AADAT)
NLE: 100584784(AADAT)
MCC: 695264(AADAT)
MCF: 102122792(AADAT)
CSAB: 103236521(AADAT)
RRO: 104662870(AADAT)
RBB: 108522848(AADAT)
CJC: 100403876(AADAT)
SBQ: 101047103(AADAT)
MMU: 23923(Aadat)
MCAL: 110299840(Aadat)
MPAH: 110336979(Aadat)
RNO: 29416(Aadat)
MUN: 110543366
CGE: 100771752
NGI: 103727134(Aadat)
HGL: 101707012(Aadat)
CCAN: 109677660(Aadat)
OCU: 100355602(AADAT)
TUP: 102479498(AADAT)
CFA: 486059(AADAT)
VVP: 112934158(AADAT)
AML: 100469458(AADAT)
UMR: 103658154(AADAT)
ORO: 101379671(AADAT)
ELK: 111156402
FCA: 101091616(AADAT)
PTG: 102949681(AADAT)
PPAD: 109262426(AADAT)
AJU: 106985264(AADAT)
BTA: 508929(AADAT) 520638
BOM: 102269904(AADAT) 102270370
BBUB: 102415820(AADAT)
CHX: 102190411(AADAT)
SSC: 100152011(AADAT)
CFR: 102515842(AADAT)
CDK: 105101723(AADAT)
BACU: 103002075(AADAT) 103002354
LVE: 103071573 103077196(AADAT)
DLE: 111171140
PCAD: 102981051(AADAT) 102995891
ECB: 100067095(AADAT)
EPZ: 103554076(AADAT)
EAI: 106843200(AADAT)
MYB: 102255657(AADAT)
MYD: 102764566(AADAT)
MNA: 107527518(AADAT)
HAI: 109373940
DRO: 112312469(AADAT)
PALE: 102886879(AADAT)
RAY: 107512524(AADAT)
MJV: 108404791(AADAT)
LAV: 100653952(AADAT)
MDO: 100031005
SHR: 100913887(AADAT)
PCW: 110216000(AADAT)
OAA: 100076580(AADAT)
GGA: 428728(AADAT)
MGP: 100539859(AADAT)
CJO: 107313054(AADAT)
NMEL: 110398293(AADAT)
APLA: 101797673(AADAT)
ACYG: 106032348(AADAT)
TGU: 100228964(AADAT)
LSR: 110483400(AADAT)
SCAN: 103825924(AADAT)
GFR: 102038773(AADAT)
FAB: 101817402(AADAT)
PHI: 102114032(AADAT)
PMAJ: 107203407(AADAT)
CCAE: 111927908(AADAT)
CCW: 104690544(AADAT)
ETL: 114065438(AADAT)
FPG: 101916601(AADAT)
FCH: 102059338(AADAT)
CLV: 102087961(AADAT)
EGZ: 104123112(AADAT)
NNI: 104021266(AADAT)
ACUN: 113479346(AADAT)
PADL: 103922551(AADAT)
AAM: 106484015(AADAT)
ASN: 102384291
AMJ: 102573373(AADAT)
PSS: 102443615 102463594(AADAT)
CMY: 102933210(AADAT)
CPIC: 101933473(AADAT) 101949101
PVT: 110085380(AADAT) 110085384
PBI: 103050097(AADAT)
PMUR: 107286149(AADAT)
TSR: 106549085(AADAT)
PMUA: 114603887 114604287(AADAT)
GJA: 107107125(AADAT) 107107127
XLA: 398787(aadat.L) 432067(aadat.S)
XTR: 496662(aadat)
NPR: 108789894(AADAT)
DRE: 557979(aadat)
SRX: 107747859(aadat)
SANH: 107692820(aadat)
SGH: 107553806(aadat)
CCAR: 109055696
IPU: 108267547(aadat)
PHYP: 113539769(aadat)
AMEX: 103040807(aadat)
EEE: 113585158(aadat)
TRU: 101078353(aadat)
LCO: 104938006(aadat)
NCC: 104951126(aadat)
MZE: 101487147(aadat)
ONL: 100694950(aadat)
OLA: 101156284(aadat)
XMA: 102233774(aadat)
XCO: 114157293(aadat)
PRET: 103475938(aadat)
CVG: 107085254(aadat)
NFU: 107377046(aadat)
KMR: 108249082(aadat)
ALIM: 106530442(aadat)
AOCE: 111576833(aadat)
CSEM: 103388590(aadat)
POV: 109634852(aadat)
LCF: 108903085(aadat)
SDU: 111235631(aadat)
SLAL: 111647152(aadat) 111654725
HCQ: 109508374(aadat)
BPEC: 110170749(aadat)
MALB: 109971451(aadat)
SASA: 106608880(aadat)
OTW: 112214602(aadat)
SALP: 111952834(aadat)
ELS: 105026755(aadat)
SFM: 108921052(aadat)
PKI: 111850985(aadat)
LCM: 102363875(AADAT)
CMK: 103180238(aadat)
ACEP: 105626664
TCA: 662228
DPA: 109533718
ATD: 109595699
NVL: 108561682
BMOR: 101738563
BMAN: 114251865
PMAC: 106710609
PRAP: 110992721
HAW: 110378047
TNL: 113495871
PXY: 105390263
AGS: 114132211
RMD: 113548790
BTAB: 109032104
FCD: 110857982
CRG: 105325199
APRO: F751_0981
DFA: DFA_03567
NGD: NGA_2018300(AADAT) NGA_2105700(ARO8)
SPAR: SPRG_07237
 » show all
Reference
  Authors
Han Q, Cai T, Tagle DA, Robinson H, Li J
  Title
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II.
  Journal
Biosci Rep 28:205-15 (2008)
DOI:10.1042/BSR20080085
  Sequence
[hsa:51166]
LinkDB

KEGG   ORTHOLOGY: K05825
Entry
K05825                      KO                                     

Name
LYSN
Definition
2-aminoadipate transaminase [EC:2.6.1.-]
Pathway
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01210  2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05825  LYSN; 2-aminoadipate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.-  
     K05825  LYSN; 2-aminoadipate transaminase
Other DBs
RN: R01939
Genes
ENL: A3UG_17485
ECLG: EC036_34130
ECLE: ECNIH2_17680
ECLN: ECNIH4_05470
ECLX: LI66_17315
ECLY: LI62_18830
ECLO: ENC_29050
EHM: AB284_08425
EXF: BFV63_16935
EAU: DI57_02005
EEC: EcWSU1_03463(ydcR)
KPU: KP1_4690
KPP: A79E_0707
KPJ: N559_0766
KPX: PMK1_00891(lysN_1)
KPNU: LI86_03710
KPNK: BN49_0689
KVA: Kvar_0676
KPE: KPK_0703
KOX: KOX_02830
KOE: A225_5015
EAE: EAE_03445
EAR: CCG33298
RTG: NCTC13098_00938(lysN_1)
REE: electrica_00669(lysN)
KIE: NCTC12125_04616(lysN)
AHN: NCTC12129_02591(ydcR1_1)
EBF: D782_3268
YPA: YPA_1318
YPM: YP_1678(aRO81)
YPD: YPD4_1703
YPX: YPD8_1845
YPW: CH59_3732
YPV: BZ15_1606
YPL: CH46_3179
YPO: BZ17_537
YPY: YPK_2257
YPB: YPTS_1983
YPQ: DJ40_381
YPU: BZ21_1205
YPR: BZ20_184
YPC: BZ23_1488
YPF: BZ19_1280
YIN: CH53_3677
ETA: ETA_17300
XCC: XCC1838(avtA)
XCB: XC_2351
XCP: XCR_2091
XCV: XCV1904
XAX: XACM_1885
XAC: XAC1858(avtA)
XCI: XCAW_02542(avtA)
XOM: XOO2745(XOO2745)
XOO: XOO2895(avtA)
XOP: PXO_00093
XOR: XOC_2247
XPH: XppCFBP6546_20090(XppCFBP6546P_20090)
PSUW: WQ53_15200
VVY: VVA0472
VAG: N646_3817
VSP: VS_II1403
VSC: VSVS12_03380(lysN)
VTA: B0818
PAEV: N297_1700
PAEI: N296_1700
PAEP: PA1S_17740
PAEM: U769_17470
PAEL: T223_18800
PAEG: AI22_16240
PAEC: M802_1697(lysN)
PAEO: M801_1699(lysN)
PMY: Pmen_2671
PMK: MDS_2045
PPSE: BN5_2413
PCQ: PcP3B5_39890(lysN_2)
PPF: Pput_1987
PSYR: N018_08580
PFL: PFL_4362
PPRC: PFLCHA0_c44340(lysN)
PPRO: PPC_4472
PFS: PFLU_4353
PFE: PSF113_4328(aspB-4)
PSA: PST_2335
PSTT: CH92_08405
PKC: PKB_1874
PSES: PSCI_3685
PSEM: TO66_22820
PSOS: POS17_4439
PANR: A7J50_4031
PSET: THL1_3703
PALL: UYA_10370
MVS: MVIS_1348
LHA: LHA_0499
MCA: MCA2997
METL: U737_23925
MMAI: sS8_4490
GAI: IMCC3135_15100(lysN_1)
AHA: AHA_3484
AVR: B565_0864
AMED: B224_0613
ACAV: VI35_04100
AEL: NCTC12917_00855(lysN)
TAU: Tola_0062
OCE: GU3_04555
LHK: LHK_01065
PSE: NH8B_3293
AMAH: DLM_0304
RSO: RSc0985
RSE: F504_245(aspB-4) F504_948
RSY: RSUY_14060(lysN_1) RSUY_30500(lysN_3)
REH: H16_A2662(h16_A2662)
CGD: CR3_1925
BMA: BMA1952
BPS: BPSL1083
BCN: Bcen_1739
BYI: BYI23_A007830(gntR)
BUE: BRPE67_ACDS07810(gntR)
BXE: Bxe_A3332
BXB: DR64_1032
BPH: Bphy_2117
BFN: OI25_546
PPNO: DA70_07460
PPNM: LV28_23220
PLG: NCTC10937_01822(lysN)
HYF: DTO96_101870(lysN_1)
CABA: SBC2_11830(lysN_1) SBC2_59730(lysN_2)
BPE: BP3685
BPAR: BN117_0235
BHZ: ACR54_00127(lysN_1) ACR54_00240(lysN_2)
BTRM: SAMEA390648701347(lysN_1) SAMEA390648701441(lysN_2)
AXX: ERS451415_05871(lysN_4) ERS451415_06073(lysN_5)
TEA: KUI_0613
TEG: KUK_0482
TAS: TASI_0658
TAT: KUM_0365
PUT: PT7_2774
AMIM: MIM_c13130
BPSI: IX83_07900
AFQ: AFA_17650
ODI: ODI_R4350
LIM: L103DPR2_02084(lysN)
LIH: L63ED372_00030(lysN_1) L63ED372_01325(lysN_2)
HPSE: HPF_10180(lysN1) HPF_21300(lysN2)
CBAA: SRAA_0534
CBAB: SMCB_0407
MPT: Mpe_A0186
HAR: HEAR0787
MMS: mma_0702(aro8)
JAG: GJA_1490(lysN) GJA_900
CFU: CFU_2538(avtA)
CARE: LT85_2055
OFO: BRW83_0930(lysN)
LCH: Lcho_3539
TIN: Tint_2790
THI: THI_3338
RGE: RGE_02400
AZA: AZKH_1543
KCI: CKCE_0549
KCT: CDEE_0141
KBT: BCUE_0135
KDE: CDSE_0137
KGA: ST1E_0146
KON: CONE_0130
KSO: CKSOR_00659(lysN)
WSU: WS0784(aspB)
ABU: Abu_2022
ABT: ABED_1829
ATP: ATR_1623
AELL: AELL_2510
AAQI: AAQM_2199
ACIB: ACBT_0509
ASUI: ASUIS_2285
ACRE: ACRYA_0364
ACLO: ACLO_2332
ALK: ALEK_2500
AMYT: AMYT_1921
AMAR: AMRN_1873
ACAA: ACAN_1888
AMOL: AMOL_1913
APAI: APAC_2199
APOC: APORC_0321
HBV: ABIV_1697
HEBR: AEBR_2015
PACO: AACT_2625
ARC: ABLL_2512
SDL: Sdel_1642
SMUL: SMUL_2283
SHAL: SHALO_2025
SULJ: SJPD1_2031
DVU: DVU2364
DVL: Dvul_0898
DVM: DvMF_3003
DDE: Dde_1376
DMA: DMR_38090
DGG: DGI_0605
DFL: DFE_1839(lysN)
DHY: DESAM_21617(lysN)
DAS: Daes_2061
DPI: BN4_10029(lysN)
PPRF: DPRO_0029
DBA: Dbac_3055
DPS: DP1610
DALK: DSCA_38830
MXA: MXAN_0212
CCX: COCOR_07829(lysN)
SCL: sce0063
BJA: bll2612(bll2612)
BRS: S23_53520
AOL: S58_53940
BRAD: BF49_2115
BARH: WN72_13620
VGO: GJW-30_1_01409(lysN)
BVR: BVIR_2039
RBM: TEF_19275
CAK: Caul_0771
PDE: Pden_4380
PGD: Gal_02826
ROH: FIU89_00435(lysN1)
AHT: ANTHELSMS3_02526(lysN)
MALU: KU6B_33320(avtA)
SECH: B18_20060
BSX: C663_0971(yhdI1)
BAMP: B938_16135
BAML: BAM5036_3063(lysN)
BAMN: BASU_3062(lysN)
BAMT: AJ82_17795
BAMY: V529_34110
BMP: NG74_03305(lysN)
BAO: BAMF_3270(RBAM_031480)
BQY: MUS_3744
BAMI: KSO_003380
BAMC: U471_32680
BAMF: U722_16890
BMQ: BMQ_3335
BMD: BMD_3340
BMEG: BG04_248
BAG: Bcoa_0706
BCOA: BF29_2989
BACP: SB24_13000
BACB: OY17_18995
BCL: ABC1503
BKW: BkAM31D_04290(lysN_1) BkAM31D_25085(lysN_2)
LSP: Bsph_3462
PASA: BAOM_4979
PSYO: PB01_17175
LMOE: BN418_2525
LMOB: BN419_2530
PPO: PPM_1398(avtA) PPM_3389(M1_3754)
PMW: B2K_03340
PSWU: SY83_22215
PBK: Back11_29350(avtA)
ASOC: CB4_02543(lysN_5)
SIV: SSIL_3495
JEO: JMA_28660
KZO: NCTC404_01828(gabR_2) NCTC404_02307(lysN)
LBU: LBUL_0737
LDL: LBU_0690
LCS: LCBD_2834
LCE: LC2W_2809
LPAP: LBPC_2593
LRH: LGG_02639(avtA)
LRG: LRHM_2535
LRL: LC705_02644(avtA)
LRA: LRHK_2749
LPJ: JDM1_2568
LPZ: Lp16_2524
LRT: LRI_1629
LFE: LAF_1013
LFR: LC40_0665
LFF: LBFF_1107
LSN: LSA_02330
LBH: Lbuc_2297
LHIL: G8J22_02726(lysN)
LBR: LVIS_2087
LRM: LRC_16620
PCE: PECL_1583
OOE: OEOE_0411
LME: LEUM_0372
LMM: MI1_01595
LMK: LMES_0311
LCI: LCK_00739
CPR: CPR_1924
CBO: CBO1802
CBA: CLB_1737
CBH: CLC_1744
CBY: CLM_1959
CBL: CLK_1183
CBB: CLD_2838
CBI: CLJ_B1980
CBT: CLH_0941
CBF: CLI_1797
CBM: CBF_1776
CKL: CKL_0439
CKR: CKR_0384
CPAS: Clopa_0749
CSB: CLSA_c11430(yisV1)
CBV: U729_3043
CLD: CLSPO_c17920(lysN)
CTYK: CTK_C05330
AMT: Amet_0031
HHW: NCTC503_01377(lysN_1)
ESR: ES1_08060
ESU: EUS_22600
CCEL: CCDG5_1722
RCH: RUM_10060
BPRO: PMF13cell1_04093(lysN_1) PMF13cell1_04094(lysN_2)
CPRO: CPRO_29450(lysN_3) CPRO_29460(lysN_4)
ERT: EUR_17010
PHX: KGNDJEFE_00200(lysN_1)
DHD: Dhaf_3288
SGY: Sgly_1315
OVA: OBV_01490
TACI: TDSAC_0775
PIV: NCTC13079_00084(lysN)
CAD: Curi_c14420(lysN)
VPR: Vpar_0748
VRM: 44547418_00757(lysN)
VDN: NCTC11831_01200(lysN)
PUF: UFO1_0406
MANA: MAMMFC1_01159(lysN_3)
STED: SPTER_44000(lysN)
AIN: Acin_2092
PFAC: PFJ30894_01014(lysN)
MALV: MALV_14660
CVA: CVAR_1679(pdxR)
NFA: NFA_9700
NFR: ERS450000_03147(lysN)
NSR: NS506_07325(lysN)
NAD: NCTC11293_01824(lysN)
RER: RER_20820
REY: O5Y_09920
ROP: ROP_63240
REQ: REQ_34140
RFA: A3L23_00105(lysN_1) A3L23_03752(lysN_4)
RHS: A3Q41_03307(lysN_3) A3Q41_04488(lysN_4)
GBR: Gbro_4078
GOR: KTR9_4009
GRU: GCWB2_20420(lysN)
GOM: D7316_04408(lysN_1)
TPR: Tpau_0992
SCO: SCO3306(SCE68.04c)
SALB: XNR_3538
SGR: SGR_5288
SGB: WQO_12230
SBH: SBI_06343
SHY: SHJG_1715
SVE: SVEN_5774
SDV: BN159_3971(lysN)
SALS: SLNWT_7007
SALU: DC74_3697
SALL: SAZ_19645
STRE: GZL_05193
SLD: T261_4813
SAMB: SAM23877_4248(lysN)
SLE: sle_31410(sle_31410)
STRD: NI25_16680
SLAU: SLA_2446
SLX: SLAV_21875(lysN2)
SFK: KY5_4552
SGE: DWG14_03695(lysN_1)
LXL: KDY119_00009(lysN)
LXX: Lxx25240(avtA)
CMI: CMM_2969
CMS: CMS3105
CMC: CMN_02941
MTS: MTES_1307
AUW: AURUGA1_01608(lysN)
ARM: ART_2864
AAU: AAur_3885
KVR: CIB50_0000797(lysN_1) CIB50_0000908(lysN_2)
JDE: Jden_2549
LMOI: VV02_11295
XCE: Xcel_3370
CFI: Celf_3800
SERJ: SGUI_0403
PAC: PPA2337
PACC: PAC1_11935
PACH: PAGK_2245
CACN: RN83_00325
ACIJ: JS278_03139(lysN_2)
NCA: Noca_4690
NDK: I601_1263(lysN_1)
NBE: Back2_16820(avtA)
KFL: Kfla_7072
PSIM: KR76_23175
TFU: Tfu_1641
NDA: Ndas_2237
NAL: B005_4588
STRR: EKD16_12130(lysN2)
TCU: Tcur_4975
SRO: Sros_9379
ACE: Acel_2152
GOB: Gobs_5087
KRA: Krad_3585
SEN: SACE_7388(avtA)
SACC: EYD13_21980(lysN2)
AMD: AMED_9357(avtA)
AMN: RAM_47980
AMM: AMES_9218(avtA)
AMZ: B737_9220(avtA)
AMQ: AMETH_7065(avtA)
AMYY: YIM_48245(lysN4)
PSEA: WY02_16360
PSEE: FRP1_26425
PSEH: XF36_25430
PAUT: Pdca_68250(avtA)
KAL: KALB_8832
ACTI: UA75_30805
ACAD: UA74_30270
AHG: AHOG_27960(lysN2)
CAI: Caci_9047
AHE: Arch_1812
TPYO: X956_00125
TBW: NCTC13354_01050(lysN)
AHW: NCTC11636_01719(lysN)
AIR: NCTC12972_01909(lysN)
ASLA: NCTC11923_00536(lysN)
AVC: NCTC10951_02304(lysN)
BAST: BAST_1683
BCOR: BCOR_0026
TBI: Tbis_3581
RXY: Rxyl_2328
EYY: EGYY_28180(ARO8)
GPA: GPA_11850
APV: Apar_0318
CBAC: JI75_01050
CYA: CYA_1709
CYB: CYB_0340
NSH: GXM_00641
HAU: Haur_1887
ATM: ANT_14860
ABAT: CFX1CAM_1556(lysN)
DRA: DR_1588
DGE: Dgeo_2084
DFC: DFI_02270
TRA: Trad_1414
TTH: TT_C0043
TTJ: TTHA0411
TAQ: TO73_1553
OTE: Oter_0766
OBG: Verru16b_03350(lysN)
CAA: Caka_0677
RUL: UC8_42720(lysN)
ROL: CA51_06260(lysN)
AHEL: Q31a_15680(lysN)
LCRE: Pla8534_69790(lysN)
TTF: THTE_0064
PLS: VT03_11910(lysN)
PLH: VT85_19375(lysN)
FMR: Fuma_02270(lysN)
GMR: GmarT_58520(lysN)
MRI: Mal4_36070(lysN)
SDYN: Mal52_15990(lysN)
PLON: Pla110_10720(lysN)
GES: VT84_34985(lysN)
FTJ: FTUN_3856
IPA: Isop_0345
SACI: Sinac_2242
PBOR: BSF38_01254(lysN)
AGV: OJF2_22110(lysN)
LBF: LBF_1402
BRM: Bmur_2616
BIP: Bint_1040
SUS: Acid_0291
ABAC: LuPra_01103(lysN_1) LuPra_03534(lysN_2)
EMI: Emin_0421
BXY: BXY_10070
BOA: Bovatus_02363(lysN)
PSAC: PSM36_0960
PDI: BDI_1252
BACC: BRDCF_p1363(ydcR)
SDJ: NCTC13534_01107(norG)
CHU: CHU_0708
CLI: Clim_0073
PPH: Ppha_0068
TMW: THMA_1154
TMQ: THMB_1154
TMX: THMC_1154
TRQ: TRQ2_1680
TNA: CTN_1439
TNP: Tnap_1634
TLE: Tlet_1766
TME: Tmel_0110
TAF: THA_342
THER: Y592_01725
FNO: Fnod_0105
MARN: LN42_00985
DTN: DTL3_1476
KOL: Kole_2166
ASAC: ATHSA_1641
CEX: CSE_07050
DTU: Dtur_0865
BANA: BARAN1_0101(lysN)
MMP: MMP0096
MMD: GYY_00490
MMAD: MMJJ_09980(lysN)
METH: MBMB1_1262
MFC: BRM9_0476
MFI: DSM1535_0457(lysN)
MCUB: MCBB_1472
TAC: Ta1193
TVO: TVG0393535(TVG0393535)
PTO: PTO0509
FAI: FAD_1777(lysN)
CDIV: CPM_0502
ABI: Aboo_1434
PFU: PF0121
PFI: PFC_07595
PHO: PH0207(PH0207)
PAB: PAB2227
PYN: PNA2_0723
TKO: TK0186
TGA: TGAM_1056
THE: GQS_08980
THA: TAM4_626
THM: CL1_1397
TNU: BD01_1734
TEU: TEU_00615
PPAC: PAP_04820
MHI: Mhar_1171
MEMA: MMAB1_1196
MBN: Mboo_0464
MPL: Mpal_1681
MPD: MCP_2159
MEZ: Mtc_2158
RCI: RRC4
NMG: Nmag_0093
APE: APE_0169.1(agt)
ACJ: ACAM_0133(agt)
SMR: Smar_1339
IHO: Igni_0859
IIS: EYM_03550
IAG: Igag_0939
HBU: Hbut_0415
STO: STK_14110
SSO: SSO0104(aspB-1)
SOL: Ssol_1080
SSOA: SULA_1119
SSOL: SULB_1120
SSOF: SULC_1118
SAI: Saci_1507
SID: M164_2027
SII: LD85_2284
SIH: SiH_1966
SIR: SiRe_1893
SIC: SiL_1873
AHO: Ahos_0582
PAI: PAE2315
PIS: Pisl_1028
TNE: Tneu_1466
TTN: TTX_0923
TUZ: TUZN_0537
ASC: ASAC_0366
ACIA: SE86_02650
KCR: Kcr_0092
 » show all
Reference
  Authors
Miyazaki T, Miyazaki J, Yamane H, Nishiyama M.
  Title
alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
  Journal
Microbiology 150:2327-34 (2004)
DOI:10.1099/mic.0.27037-0
  Sequence
[tth:TT_C0043]
LinkDB

KEGG   ORTHOLOGY: K00838
Entry
K00838                      KO                                     

Name
ARO8
Definition
aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
Pathway
ko00130  Ubiquinone and other terpenoid-quinone biosynthesis
ko00270  Cysteine and methionine metabolism
ko00300  Lysine biosynthesis
ko00350  Tyrosine metabolism
ko00360  Phenylalanine metabolism
ko00380  Tryptophan metabolism
ko00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ko00401  Novobiocin biosynthesis
ko00950  Isoquinoline alkaloid biosynthesis
ko00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00024  Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
M00025  Tyrosine biosynthesis, chorismate => HPP => tyrosine
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00034  Methionine salvage pathway
M00044  Tyrosine degradation, tyrosine => homogentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00300 Lysine biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00350 Tyrosine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00360 Phenylalanine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00380 Tryptophan metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00401 Novobiocin biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.5  tyrosine transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.27  tryptophan transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.39  2-aminoadipate transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.57  aromatic-amino-acid transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Other DBs
RN: R00694 R00734 R01939
COG: COG1167
GO: 0008793 0047536
Genes
QSU: 112001990 112026216
MNG: MNEG_3800
SCE: YGL202W(ARO8)
AGO: AGOS_AFR548C AGOS_AGR167W
ERC: Ecym_7228
KLA: KLLA0_A04906g KLLA0_F10021g
KMX: KLMA_20259(ARO8) KLMA_50151(ARO8)
LTH: KLTH0E07678g KLTH0G02002g
VPO: Kpol_278p2
ZRO: ZYRO0C06028g
NCS: NCAS_0E00670(NCAS0E00670)
NDI: NDAI_0I02830(NDAI0I02830)
TPF: TPHA_0D03370(TPHA0D03370)
TDL: TDEL_0D05790(TDEL0D05790)
KAF: KAFR_0D01420(KAFR0D01420)
PIC: PICST_66767(ARO8)
CAL: CAALFM_C200340CA(ARO8)
SLB: AWJ20_1088(ARO8)
NCR: NCU09116
MGR: MGG_09919
SSCK: SPSK_08879
MAW: MAC_07121
MAJ: MAA_00168
CMT: CCM_06988
BFU: BCIN_07g04780(Bcaro8)
MBE: MBM_09282
ANG: ANI_1_2088024(An02g00030) ANI_1_766024(An02g05540)
ABE: ARB_01306
TVE: TRV_00012
PTE: PTT_08476
ABP: AGABI1DRAFT113513(AGABI1DRAFT_113513)
ABV: AGABI2DRAFT191838(AGABI2DRAFT_191838)
SMIN: v1.2.016220.t1(symbB.v1.2.016220.t1)
 » show all
Reference
PMID:9491083
  Authors
Iraqui I, Vissers S, Cartiaux M, Urrestarazu A
  Title
Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.
  Journal
Mol Gen Genet 257:238-48 (1998)
DOI:10.1007/s004380050644
  Sequence
[sce:YGL202W]
LinkDB

KEGG   ENZYME: 2.6.1.39
Entry
EC 2.6.1.39                 Enzyme                                 

Name
2-aminoadipate transaminase;
alpha-aminoadipate aminotransferase;
2-aminoadipate aminotransferase;
2-aminoadipic aminotransferase;
glutamic-ketoadipic transaminase;
glutamate-alpha-ketoadipate transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
L-2-aminoadipate:2-oxoglutarate aminotransferase
Reaction(IUBMB)
L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate [RN:R01939]
Reaction(KEGG)
R01939
Substrate
L-2-aminoadipate [CPD:C00956];
2-oxoglutarate [CPD:C00026]
Product
2-oxoadipate [CPD:C00322];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.39 created 1972
Pathway
ec00300  Lysine biosynthesis
ec00310  Lysine degradation
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K00825  kynurenine/2-aminoadipate aminotransferase
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Genes
HSA: 51166(AADAT)
PTR: 461601(AADAT)
PPS: 100995091(AADAT)
GGO: 101151419(AADAT)
PON: 100435746(AADAT)
NLE: 100584784(AADAT)
MCC: 695264(AADAT)
MCF: 102122792(AADAT)
CSAB: 103236521(AADAT)
RRO: 104662870(AADAT)
RBB: 108522848(AADAT)
CJC: 100403876(AADAT)
SBQ: 101047103(AADAT)
MMU: 23923(Aadat)
MCAL: 110299840(Aadat)
MPAH: 110336979(Aadat)
RNO: 29416(Aadat)
MUN: 110543366
CGE: 100771752
NGI: 103727134(Aadat)
HGL: 101707012(Aadat)
CCAN: 109677660(Aadat)
OCU: 100355602(AADAT)
TUP: 102479498(AADAT)
CFA: 486059(AADAT)
VVP: 112934158(AADAT)
AML: 100469458(AADAT)
UMR: 103658154(AADAT)
ORO: 101379671(AADAT)
ELK: 111156402
FCA: 101091616(AADAT)
PTG: 102949681(AADAT)
PPAD: 109262426(AADAT)
AJU: 106985264(AADAT)
BTA: 508929(AADAT) 520638
BOM: 102269904(AADAT) 102270370
BBUB: 102415820(AADAT)
CHX: 102190411(AADAT)
SSC: 100152011(AADAT)
CFR: 102515842(AADAT)
CDK: 105101723(AADAT)
BACU: 103002075(AADAT) 103002354
LVE: 103071573 103077196(AADAT)
DLE: 111171140
PCAD: 102981051(AADAT) 102995891
ECB: 100067095(AADAT)
EPZ: 103554076(AADAT)
EAI: 106843200(AADAT)
MYB: 102255657(AADAT)
MYD: 102764566(AADAT)
MNA: 107527518(AADAT)
HAI: 109373940
DRO: 112312469(AADAT)
PALE: 102886879(AADAT)
RAY: 107512524(AADAT)
MJV: 108404791(AADAT)
LAV: 100653952(AADAT)
MDO: 100031005
SHR: 100913887(AADAT)
PCW: 110216000(AADAT)
OAA: 100076580(AADAT)
GGA: 428728(AADAT)
MGP: 100539859(AADAT)
CJO: 107313054(AADAT)
NMEL: 110398293(AADAT)
APLA: 101797673(AADAT)
ACYG: 106032348(AADAT)
TGU: 100228964(AADAT)
LSR: 110483400(AADAT)
SCAN: 103825924(AADAT)
GFR: 102038773(AADAT)
FAB: 101817402(AADAT)
PHI: 102114032(AADAT)
PMAJ: 107203407(AADAT)
CCAE: 111927908(AADAT)
CCW: 104690544(AADAT)
ETL: 114065438(AADAT)
FPG: 101916601(AADAT)
FCH: 102059338(AADAT)
CLV: 102087961(AADAT)
EGZ: 104123112(AADAT)
NNI: 104021266(AADAT)
ACUN: 113479346(AADAT)
PADL: 103922551(AADAT)
AAM: 106484015(AADAT)
ASN: 102384291
AMJ: 102573373(AADAT)
PSS: 102443615 102463594(AADAT)
CMY: 102933210(AADAT)
CPIC: 101933473(AADAT) 101949101
PVT: 110085380(AADAT) 110085384
PBI: 103050097(AADAT)
PMUR: 107286149(AADAT)
TSR: 106549085(AADAT)
PMUA: 114603887 114604287(AADAT)
GJA: 107107125(AADAT) 107107127
XLA: 398787(aadat.L) 432067(aadat.S)
XTR: 496662(aadat)
NPR: 108789894(AADAT)
DRE: 557979(aadat)
SRX: 107747859(aadat)
SANH: 107692820(aadat)
SGH: 107553806(aadat)
CCAR: 109055696
IPU: 108267547(aadat)
PHYP: 113539769(aadat)
AMEX: 103040807(aadat)
EEE: 113585158(aadat)
TRU: 101078353(aadat)
LCO: 104938006(aadat)
NCC: 104951126(aadat)
MZE: 101487147(aadat)
ONL: 100694950(aadat)
OLA: 101156284(aadat)
XMA: 102233774(aadat)
XCO: 114157293(aadat)
PRET: 103475938(aadat)
CVG: 107085254(aadat)
NFU: 107377046(aadat)
KMR: 108249082(aadat)
ALIM: 106530442(aadat)
AOCE: 111576833(aadat)
CSEM: 103388590(aadat)
POV: 109634852(aadat)
LCF: 108903085(aadat)
SDU: 111235631(aadat)
SLAL: 111647152(aadat) 111654725
HCQ: 109508374(aadat)
BPEC: 110170749(aadat)
MALB: 109971451(aadat)
SASA: 106608880(aadat)
OTW: 112214602(aadat)
SALP: 111952834(aadat)
ELS: 105026755(aadat)
SFM: 108921052(aadat)
PKI: 111850985(aadat)
LCM: 102363875(AADAT)
CMK: 103180238(aadat)
ACEP: 105626664
TCA: 662228
DPA: 109533718
ATD: 109595699
NVL: 108561682
BMOR: 101738563
BMAN: 114251865
PMAC: 106710609
PRAP: 110992721
HAW: 110378047
TNL: 113495871
PXY: 105390263
AGS: 114132211
RMD: 113548790
BTAB: 109032104
FCD: 110857982
CRG: 105325199
MNG: MNEG_3800
APRO: F751_0981
SCE: YGL202W(ARO8)
ERC: Ecym_7228
KMX: KLMA_20259(ARO8) KLMA_50151(ARO8)
NCS: NCAS_0E00670(NCAS0E00670)
NDI: NDAI_0I02830(NDAI0I02830)
TPF: TPHA_0D03370(TPHA0D03370)
TDL: TDEL_0D05790(TDEL0D05790)
KAF: KAFR_0D01420(KAFR0D01420)
PIC: PICST_66767(ARO8)
CAL: CAALFM_C200340CA(ARO8)
SLB: AWJ20_1088(ARO8)
NCR: NCU09116
MGR: MGG_09919
SSCK: SPSK_08879
MAW: MAC_07121
MAJ: MAA_00168
CMT: CCM_06988
BFU: BCIN_07g04780(Bcaro8)
MBE: MBM_09282
ANG: ANI_1_2088024(An02g00030) ANI_1_766024(An02g05540)
ABE: ARB_01306
TVE: TRV_00012
PTE: PTT_08476
ABP: AGABI1DRAFT113513(AGABI1DRAFT_113513)
ABV: AGABI2DRAFT191838(AGABI2DRAFT_191838)
DFA: DFA_03567
SMIN: v1.2.016220.t1(symbB.v1.2.016220.t1)
NGD: NGA_2018300(AADAT) NGA_2105700(ARO8)
SPAR: SPRG_07237
 » show all
Reference
1  [PMID:5792664]
  Authors
Matsuda M, Ogur M.
  Title
Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase.
  Journal
J Biol Chem 244:3352-8 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.39
IUBMB Enzyme Nomenclature: 2.6.1.39
ExPASy - ENZYME nomenclature database: 2.6.1.39
BRENDA, the Enzyme Database: 2.6.1.39
CAS: 9033-00-5
LinkDB

KEGG   REACTION: R01939
Entry
R01939                      Reaction                               

Name
L-2-aminoadipate:2-oxoglutarate aminotransferase
Definition
L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026  C00322_C00956
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
K05825  2-aminoadipate transaminase [EC:2.6.1.-]
Other DBs
RHEA: 12604
LinkDB

DBGET integrated database retrieval system