KEGG   ORTHOLOGY: K00838Help
Entry
K00838                      KO                                     

Name
ARO8
Definition
aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
Pathway
ko00130  Ubiquinone and other terpenoid-quinone biosynthesis
ko00270  Cysteine and methionine metabolism
ko00300  Lysine biosynthesis
ko00350  Tyrosine metabolism
ko00360  Phenylalanine metabolism
ko00380  Tryptophan metabolism
ko00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ko00401  Novobiocin biosynthesis
ko00950  Isoquinoline alkaloid biosynthesis
ko00960  Tropane, piperidine and pyridine alkaloid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01130  Biosynthesis of antibiotics
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00024  Phenylalanine biosynthesis, chorismate => phenylalanine
M00025  Tyrosine biosynthesis, chorismate => tyrosine
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00034  Methionine salvage pathway
M00044  Tyrosine degradation, tyrosine => homogentisate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00300 Lysine biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00350 Tyrosine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00360 Phenylalanine metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00380 Tryptophan metabolism
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
   00401 Novobiocin biosynthesis
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.5  tyrosine transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.27  tryptophan transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.39  2-aminoadipate transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
    2.6.1.57  aromatic-amino-acid transaminase
     K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K00838  ARO8; aromatic amino acid aminotransferase I / 2-aminoadipate transaminase
BRITE hierarchy
Other DBs
RN: R00694 R00734 R01939
COG: COG1167
GO: 0008793 0047536
Genes
QSU: 112001990 112026216
MNG: MNEG_3800
SCE: YGL202W(ARO8)
AGO: AGOS_AFR548C
ERC: Ecym_7228
KLA: KLLA0_A04906g KLLA0_F10021g
KMX: KLMA_20259(ARO8) KLMA_50151(ARO8)
LTH: KLTH0E07678g KLTH0G02002g
VPO: Kpol_278p2
ZRO: ZYRO0C06028g
NCS: NCAS_0E00670(NCAS0E00670)
NDI: NDAI_0I02830(NDAI0I02830)
TPF: TPHA_0D03370(TPHA0D03370)
TDL: TDEL_0D05790(TDEL0D05790)
KAF: KAFR_0D01420(KAFR0D01420)
PIC: PICST_66767(ARO8)
CAL: CAALFM_C200340CA(ARO8)
SLB: AWJ20_1088(ARO8)
NCR: NCU09116
MGR: MGG_09919
SSCK: SPSK_08879
MAW: MAC_07121
MAJ: MAA_00168
CMT: CCM_06988
MBE: MBM_09282
ANG: ANI_1_2088024(An02g00030) ANI_1_766024(An02g05540)
ABE: ARB_01306
TVE: TRV_00012
PTE: PTT_08476
ABP: AGABI1DRAFT113513(AGABI1DRAFT_113513)
ABV: AGABI2DRAFT191838(AGABI2DRAFT_191838)
SMIN: v1.2.016220.t1(symbB.v1.2.016220.t1)
NGD: NGA_2105700(ARO8)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9491083
  Authors
Iraqui I, Vissers S, Cartiaux M, Urrestarazu A
  Title
Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.
  Journal
Mol Gen Genet 257:238-48 (1998)
DOI:10.1007/s004380050644
  Sequence
[sce:YGL202W]
LinkDB All DBs

KEGG   REACTION: R01939Help
Entry
R01939                      Reaction                               

Name
L-2-aminoadipate:2-oxoglutarate aminotransferase
Definition
L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026  C00322_C00956
Enzyme
Pathway
rn00300  Lysine biosynthesis
rn00310  Lysine degradation
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
K00838  aromatic amino acid aminotransferase I / 2-aminoadipate transaminase [EC:2.6.1.57 2.6.1.39 2.6.1.27 2.6.1.5]
K05825  2-aminoadipate transaminase [EC:2.6.1.-]
Other DBs
RHEA: 12604
LinkDB All DBs

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