KEGG   ORTHOLOGY: K01229
Entry
K01229                      KO                                     

Name
LCT
Definition
lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62]
Pathway
ko00052  Galactose metabolism
ko01100  Metabolic pathways
ko04973  Carbohydrate digestion and absorption
Disease
H00116  Congenital lactase deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    K01229  LCT; lactase-phlorizin hydrolase
 09150 Organismal Systems
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K01229  LCT; lactase-phlorizin hydrolase
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K01229  LCT; lactase-phlorizin hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.62  glycosylceramidase
     K01229  LCT; lactase-phlorizin hydrolase
    3.2.1.108  lactase
     K01229  LCT; lactase-phlorizin hydrolase
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Others
   K01229  LCT; lactase-phlorizin hydrolase
Other DBs
RN: R01678 R06114
GO: 0000016 0017042
Genes
HSA: 3938(LCT)
PTR: 459633(LCT)
PPS: 100993974(LCT)
GGO: 101136936(LCT)
PON: 100450303(LCT)
NLE: 100602088(LCT)
MCC: 707761(LCT)
MCF: 102141036(LCT)
CSAB: 103216991(LCT)
RRO: 104665436(LCT)
RBB: 108539586(LCT)
CJC: 100408648(LCT)
SBQ: 101044226(LCT)
MMU: 226413(Lct)
MCAL: 110304188(Lct)
MPAH: 110322545(Lct)
RNO: 116569(Lct)
MUN: 110555417(Lct)
CGE: 100766856(Lct)
NGI: 103734619(Lct)
HGL: 101697396(Lct)
OCU: 100009256(LPH) 100352497(LCT) 100353264
TUP: 102470311(LCT)
CFA: 483898(LCT)
VVP: 112932617(LCT)
AML: 100484153(LCT)
UMR: 103667712(LCT)
UAH: 113263420(LCT)
ORO: 101373825(LCT)
ELK: 111143551
FCA: 101092452(LCT)
PTG: 102949288(LCT)
PPAD: 109270343(LCT)
AJU: 106969449(LCT)
BTA: 514332(LCT)
BOM: 102279578(LCT)
BIU: 109568203(LCT)
BBUB: 102410227(LCT)
CHX: 102170472(LCT)
OAS: 101104042(LCT)
SSC: 100625807(LCT) 100625897
CFR: 102513047(LCT)
CDK: 105092305(LCT)
BACU: 103003658(LCT)
LVE: 103074579(LCT)
OOR: 101270599(LCT)
DLE: 111172712(LCT)
PCAD: 102988992(LCT)
ECB: 100055369(LCT)
EPZ: 103548925(LCT)
EAI: 106836543(LCT)
MYB: 102246527(LCT)
MYD: 102761793(LCT)
MNA: 107531139(LCT)
HAI: 109392715(LCT)
DRO: 112313063(LCT)
PALE: 102887366(LCT)
RAY: 107511200(LCT)
MJV: 108405363(LCT)
LAV: 100661599(LCT)
TMU: 101348169
MDO: 100016393(LCT)
SHR: 100933904(LCT)
PCW: 110223786(LCT)
OAA: 100084941(LCT)
GGA: 424294(LCT)
MGP: 100540699(LCT)
CJO: 107316868(LCT)
NMEL: 110399364(LCT)
APLA: 101799746(LCT)
ACYG: 106039329(LCT)
TGU: 100229941(LCT)
LSR: 110480639(LCT)
SCAN: 103814626(LCT)
GFR: 102041259(LCT)
FAB: 101814034(LCT)
PHI: 102100057(LCT)
PMAJ: 107207677(LCT)
CCAE: 111932317(LCT)
CCW: 104694217(LCT)
ETL: 114057697(LCT)
FPG: 101921531(LCT)
FCH: 102058755(LCT)
CLV: 102086420(LCT)
EGZ: 104129535(LCT)
NNI: 104009760(LCT)
ACUN: 113482159(LCT)
PADL: 103912627(LCT)
AAM: 106498455(LCT)
ASN: 102370133(LCT)
AMJ: 102576031(LCT)
PSS: 102456860(LCT)
CMY: 102946778(LCT)
CPIC: 101933763(LCT)
ACS: 103279188(lct)
PVT: 110071879(LCT)
PBI: 103054678(LCT)
PMUR: 107284386(LCT)
TSR: 106540054(LCT)
PMUA: 114604625(LCT)
GJA: 107115411(LCT)
XLA: 100127248(lct.1.L) 100127291(lct.2.L)
XTR: 100145766(lct.2) 101732850
DRE: 559107 796436(lct)
IPU: 108266116(lct)
PHYP: 113525948(lct)
AMEX: 103029218(lct)
EEE: 113577223(lct)
TRU: 101076621
LCO: 104939725(lct)
NCC: 104954911(lct)
MZE: 101465201
ONL: 100703875
OLA: 101171223(lct)
XMA: 102223171(lct)
XCO: 114147572
PRET: 103461729
CVG: 107091021(lct)
NFU: 107389384(lct)
ALIM: 106522267(lct)
AOCE: 111581081
CSEM: 103392433(lct)
POV: 109631322
LCF: 108887080
SDU: 111218818
SLAL: 111667436
HCQ: 109515508(lct)
MALB: 109966332(lct)
SASA: 106586119(lct)
OTW: 112235127(lct)
SALP: 111973682(lct)
ELS: 105005862(lct)
SFM: 108928209(lct)
PKI: 111842887(lct)
SPU: 582036
 » show all
Reference
  Authors
Ingram CJ, Mulcare CA, Itan Y, Thomas MG, Swallow DM
  Title
Lactose digestion and the evolutionary genetics of lactase persistence.
  Journal
Hum Genet 124:579-91 (2009)
DOI:10.1007/s00439-008-0593-6
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