K01313                      KO                                     

coagulation factor II (thrombin) [EC:]
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04610  Complement and coagulation cascades
ko04611  Platelet activation
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
H00223  Inherited thrombophilia
H01254  Congenital prothrombin deficiency
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K01313  F2; coagulation factor II (thrombin)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K01313  F2; coagulation factor II (thrombin)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K01313  F2; coagulation factor II (thrombin)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K01313  F2; coagulation factor II (thrombin)
   04611 Platelet activation
    K01313  F2; coagulation factor II (thrombin)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K01313  F2; coagulation factor II (thrombin)
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K01313  F2; coagulation factor II (thrombin)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01313  F2; coagulation factor II (thrombin)
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K01313  F2; coagulation factor II (thrombin)
   00536 Glycosaminoglycan binding proteins
    K01313  F2; coagulation factor II (thrombin)
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases  thrombin
     K01313  F2; coagulation factor II (thrombin)
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01313  F2; coagulation factor II (thrombin)
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   K01313  F2; coagulation factor II (thrombin)
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Haparin
  Coagulation and fibrinolysis
   K01313  F2; coagulation factor II (thrombin)
HSA: 2147(F2)
PTR: 451158(F2)
PPS: 100975534(F2)
GGO: 101149905(F2)
PON: 100173859(F2)
NLE: 100595467(F2)
MCC: 712729(F2)
MCF: 102131020(F2)
CSAB: 103236354
RRO: 104668398(F2)
RBB: 108521952(F2)
CJC: 100386446(F2)
SBQ: 101049318(F2)
MMU: 14061(F2)
MCAL: 110311945(F2)
MPAH: 110319115(F2)
RNO: 29251(F2)
MUN: 110549882(F2)
CGE: 100754947(F2)
NGI: 103742495(F2)
HGL: 101720561(F2)
CCAN: 109681600(F2)
OCU: 100009146(F2)
TUP: 102468231(F2)
CFA: 100856539(F2)
VVP: 112924085(F2)
AML: 100472871(F2)
UMR: 103672390(F2)
UAH: 113264978(F2)
ORO: 101381460(F2)
ELK: 111149799
FCA: 101090463(F2)
PTG: 102950768(F2)
PPAD: 109245108(F2)
AJU: 106978029(F2)
BTA: 280685(F2)
BOM: 102271164(F2)
BIU: 109569554(F2)
BBUB: 102415273(F2)
CHX: 102185018(F2)
OAS: 100307041(F2)
SSC: 100144442(F2)
CFR: 102515763(F2)
CDK: 105106867(F2)
BACU: 103013731(F2)
LVE: 103082406(F2)
OOR: 101289120(F2)
DLE: 111183976(F2)
PCAD: 102991552(F2)
ECB: 100057521(F2)
EPZ: 103566907(F2)
EAI: 106844001(F2)
MYB: 102252492(F2)
MYD: 102752205(F2)
MNA: 107530315(F2)
HAI: 109390173(F2)
DRO: 112303389(F2)
PALE: 102877724(F2)
RAY: 107511857(F2)
MJV: 108403296(F2)
LAV: 100666651(F2)
TMU: 101347713
MDO: 100015821(F2)
SHR: 100915186(F2)
PCW: 110223959(F2)
OAA: 100081028(F2)
GGA: 395306(F2)
MGP: 100549057(F2)
CJO: 107314808(F2)
NMEL: 110400969(F2)
APLA: 101792756(F2)
ACYG: 106043598(F2)
TGU: 100220988(F2)
LSR: 110472069(F2)
SCAN: 103826687(F2)
GFR: 102034334(F2)
FAB: 101811384(F2)
PHI: 102114657(F2)
PMAJ: 107205921(F2)
CCAE: 111930178(F2)
CCW: 104697991(F2)
ETL: 114058944(F2)
FPG: 101912106(F2)
FCH: 102047000(F2)
CLV: 102087936(F2)
EGZ: 104134075(F2)
NNI: 104020379(F2)
ACUN: 113480877(F2)
PADL: 103921711(F2)
AAM: 106498225(F2)
ASN: 102370968(F2)
AMJ: 102568064(F2)
PSS: 102449827(F2)
CMY: 102937607(F2)
CPIC: 101938037(F2)
ACS: 100566916(f2)
PVT: 110081895(F2)
PBI: 103065535(F2)
PMUR: 107294859(F2)
TSR: 106554431
PMUA: 114595904(F2)
GJA: 107106779(F2)
XLA: 443652(f2.L) 446352(f2.S)
XTR: 548514(f2)
NPR: 108791599(F2)
DRE: 325881(f2)
SRX: 107742559
IPU: 108259272(f2)
PHYP: 113546761(f2)
AMEX: 103039180(f2)
EEE: 113592322(f2)
TRU: 446073(f2)
LCO: 104936791(f2)
NCC: 104959957(f2)
ONL: 100702313
OLA: 101170246
XMA: 102217884(f2)
XCO: 114140554(f2)
PRET: 103480906(f2)
CVG: 107099194(f2)
NFU: 107384579(f2)
KMR: 108228250(f2)
ALIM: 106531261(f2)
AOCE: 111587274(f2)
CSEM: 103389837(f2)
POV: 109648054(f2)
SDU: 111235568(f2)
SLAL: 111646879(f2)
HCQ: 109510409(f2)
BPEC: 110172075(f2)
MALB: 109971101(f2)
ELS: 105017464(f2)
SFM: 108940837(f2)
PKI: 111858234(f2)
LCM: 102347036(F2)
CMK: 103186030(f2)
RTP: 109918716(f2)
APLC: 110974931
PTEP: 107437472
CRG: 105327809
OBI: 106884382
NVE: 5515513
SPIS: 111328185
HMG: 100204772
 » show all
MacGillivray RT, Davie EW
Characterization of bovine prothrombin mRNA and its translation product.
Biochemistry 23:1626-34 (1984)
Glenn KC, Frost GH, Bergmann JS, Carney DH
Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis.
Pept Res 1:65-73 (1988)

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