KEGG   ORTHOLOGY: K01370
Entry
K01370                      KO                                     

Name
CASP1
Definition
caspase 1 [EC:3.4.22.36]
Pathway
ko04217  Necroptosis
ko04613  Neutrophil extracellular trap formation
ko04621  NOD-like receptor signaling pathway
ko04623  Cytosolic DNA-sensing pathway
ko04625  C-type lectin receptor signaling pathway
ko05014  Amyotrophic lateral sclerosis
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05135  Yersinia infection
ko05164  Influenza A
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K01370  CASP1; caspase 1
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K01370  CASP1; caspase 1
   04621 NOD-like receptor signaling pathway
    K01370  CASP1; caspase 1
   04623 Cytosolic DNA-sensing pathway
    K01370  CASP1; caspase 1
   04625 C-type lectin receptor signaling pathway
    K01370  CASP1; caspase 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K01370  CASP1; caspase 1
   05164 Influenza A
    K01370  CASP1; caspase 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K01370  CASP1; caspase 1
   05132 Salmonella infection
    K01370  CASP1; caspase 1
   05131 Shigellosis
    K01370  CASP1; caspase 1
   05135 Yersinia infection
    K01370  CASP1; caspase 1
   05133 Pertussis
    K01370  CASP1; caspase 1
   05134 Legionellosis
    K01370  CASP1; caspase 1
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K01370  CASP1; caspase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01370  CASP1; caspase 1
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K01370  CASP1; caspase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.36  caspase-1
     K01370  CASP1; caspase 1
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C14: caspase family
   K01370  CASP1; caspase 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   TRIM-directed selective autophagy
    K01370  CASP1; caspase 1
Genes
HSA: 834(CASP1)
PTR: 101058924(CASP1)
PPS: 100985633(CARD17) 100985973 100986637(CARD16)
GGO: 101136563
PON: 100437679(CASP1) 100442809
NLE: 100588974(CASP1)
MCC: 100426388 706568
MCF: 102118885(CASP1)
CSAB: 103248363 103248365(CASP1) 103248933
RRO: 104665271(CASP1) 104665273 104665280
RBB: 108513176 108513177 108513179(CASP1)
CJC: 100385618(CASP1)
SBQ: 101048062(CASP1)
MMU: 12362(Casp1)
MCAL: 110302061(Casp1)
MPAH: 110328145(Casp1)
RNO: 25166(Casp1)
MUN: 110552936
CGE: 100759171
NGI: 103743236(Casp1)
HGL: 101725179(Casp1)
CCAN: 109694935(Casp1)
OCU: 100101588(CASP1)
TUP: 102490614(CASP1)
BTA: 514214(CASP1)
BIU: 109570010(CASP1)
BBUB: 102395839(CASP1)
OAS: 101117013
SSC: 397319(CASP1)
CFR: 102514999(CASP1)
CDK: 105100418(CASP1)
BACU: 103013120
LVE: 103078860
OOR: 101289850(CASP1)
DLE: 111167579(CASP1)
PCAD: 102982110(CASP1)
ECB: 100033888(CASP1)
EPZ: 103559838(CASP1)
EAI: 106837656(CASP1)
MYB: 102247565 102258149(CASP1)
MYD: 102769699
MNA: 107532340
HAI: 109377701(CASP1)
DRO: 112314315(CASP1)
RAY: 107504293(CASP1)
TMU: 101359297
MDO: 100032592 100032596 100032610
SHR: 100935043
OAA: 100078458
GGA: 395764(CASP1)
MGP: 100549639
CJO: 107322632
NMEL: 110407545 110407549(CARD16)
APLA: 101789899
ACYG: 106041090
FPG: 101914004
FCH: 102051371
CLV: 102097973
EGZ: 104131761
NNI: 104012458
ACUN: 113487354
PADL: 103916608
AAM: 106484675
ASN: 102373345
AMJ: 102575910(CASP1)
PSS: 102454294
CMY: 102948326
CPIC: 101951713
ACS: 100554079
PVT: 110084544
PBI: 103067193
PMUR: 107288559
PMUA: 114585476
GJA: 107112418
XLA: 378669(casp1.S) 397719(casp1.L)
XTR: 100491605(casp1)
NPR: 108790873
DRE: 566185(caspbl) 57933(caspa)
SRX: 107713782 107719146 107723996 107737821 107738044 107748007
SANH: 107659780 107666787 107679276 107683527 107685936
SGH: 107558420 107570904 107571421 107571890 107573577 107574341 107592160 107600521
CCAR: 109055187 109059688 109062412 109079016 109089143 109093960 109094019
IPU: 108267794(CASP1)
PHYP: 113540111
AMEX: 103021832 103039157 103043169 111188785
EEE: 113573520 113574405
TRU: 101062626 101064415
LCO: 104924732
NCC: 104959782
MZE: 101463887 101464464 101468196 101481357 112429920 112431722 112432409
ONL: 100702756 100708116 100708386 102079862 102081456(card16) 102082075 106097268 109196975 112846027
OLA: 101174762
XMA: 102220363 102220624 102229031 111605766
XCO: 114133584 114133591 114133592 114142065
PRET: 103474681
CVG: 107081895 107081897 107081901
NFU: 107380030
ALIM: 106519401 106533471
AOCE: 111582467
CSEM: 103378482
POV: 109630250
LCF: 108891827
SDU: 111236860 111237425 111238154
SLAL: 111654143
HCQ: 109518426 109518427
BPEC: 110163616
SASA: 106612902
OTW: 112265961 112266955 112266982
SALP: 111959666 111982518
ELS: 105011822
SFM: 108922456
PKI: 111841516
LCM: 102363742
CMK: 103180499(caspase-1)
RTP: 109916765
 » show all
Reference
PMID:7780029
  Authors
Keane KM, Giegel DA, Lipinski WJ, Callahan MJ, Shivers BD
  Title
Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme.
  Journal
Cytokine 7:105-10 (1995)
DOI:10.1006/cyto.1995.1014
  Sequence
[rno:25166]
Reference
PMID:1373520
  Authors
Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van Ness K, Greenstreet TA, March CJ, Kronheim SR, Druck T, Cannizzaro LA, et al.
  Title
Molecular cloning of the interleukin-1 beta converting enzyme.
  Journal
Science 256:97-100 (1992)
DOI:10.1126/science.1373520
  Sequence
[hsa:834]
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