KEGG   ORTHOLOGY: K01440
Entry
K01440                      KO                                     

Name
PNC1
Definition
nicotinamidase [EC:3.5.1.19]
Pathway
ko00760  Nicotinate and nicotinamide metabolism
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
ko04213  Longevity regulating pathway - multiple species
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K01440  PNC1; nicotinamidase
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    K01440  PNC1; nicotinamidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.19  nicotinamidase
     K01440  PNC1; nicotinamidase
Other DBs
RN: R01268
COG: COG1335
GO: 0008936
Genes
SCE: YGL037C(PNC1)
AGO: AGOS_AFR466C
ERC: Ecym_1410
KMX: KLMA_40268(PNC1)
LTH: KLTH0H09086g
VPO: Kpol_1041p36
ZRO: ZYRO0G09306g
NCS: NCAS_0A01870(NCAS0A01870)
NDI: NDAI_0D03800(NDAI0D03800)
TPF: TPHA_0F00510(TPHA0F00510)
TBL: TBLA_0C04280(TBLA0C04280)
TDL: TDEL_0F02750(TDEL0F02750)
KAF: KAFR_0F03650(KAFR0F03650)
CAL: CAALFM_C703520WA(PNC1)
SLB: AWJ20_4246(PNC1)
CNE: CNA07780
 » show all
Reference
  Authors
Ghislain M, Talla E, Francois JM
  Title
Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1.
  Journal
Yeast 19:215-24 (2002)
DOI:10.1002/yea.810
Reference
  Authors
Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA
  Title
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.
  Journal
Nature 423:181-5 (2003)
DOI:10.1038/nature01578
  Sequence
[sce:YGL037C]
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