KEGG   ORTHOLOGY: K01587
Entry
K01587                      KO                                     

Name
PAICS
Definition
phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
Pathway
ko00230  Purine metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.21  phosphoribosylaminoimidazole carboxylase
     K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.6  phosphoribosylaminoimidazolesuccinocarboxamide synthase
     K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase
Other DBs
RN: R04209 R04591
GO: 0004638 0004639
Genes
HSA: 10606(PAICS)
PTR: 471236(PAICS)
PPS: 100993147(PAICS)
GGO: 101132763(PAICS)
PON: 100190835(PAICS)
NLE: 100580950
MCC: 694743
MCF: 101864855(PAICS)
CSAB: 103237366
RRO: 104655715(PAICS)
RBB: 108513484(PAICS)
CJC: 100390231(PAICS)
SBQ: 101031274(PAICS) 104651700
MMU: 67054(Paics)
MCAL: 110293933(Paics)
MPAH: 110330578(Paics)
RNO: 100910308 140946(Paics)
MUN: 110565016(Paics)
CGE: 100753190 100758991(Paics)
NGI: 103734378(Paics)
HGL: 101721606(Paics)
CCAN: 109697886(Paics)
OCU: 100343740(PAICS)
TUP: 102484181(PAICS)
CFA: 100855769
VVP: 112923709
AML: 100482672(PAICS)
UMR: 103672750(PAICS)
UAH: 113262521(PAICS)
ORO: 101383279(PAICS)
ELK: 111149362
FCA: 101084705
PTG: 102951236(PAICS)
PPAD: 109278673
AJU: 106971666
BTA: 404170(PAICS)
BOM: 102281546(PAICS)
BIU: 109560492
BBUB: 102392736
CHX: 102182773(PAICS)
SSC: 100521281(PAICS)
CFR: 102522524
CDK: 105091550
BACU: 103009147(PAICS)
LVE: 103076533(PAICS)
OOR: 101287712(PAICS)
DLE: 111169417
PCAD: 102994548(PAICS)
ECB: 100058501(PAICS)
EPZ: 103556488(PAICS)
EAI: 106841680(PAICS)
MYB: 102239537(PAICS)
MYD: 102757395(PAICS)
MNA: 107532951(PAICS)
HAI: 109373280 109394361(PAICS)
DRO: 112320919(PAICS) 112322805
PALE: 102899036(PAICS)
RAY: 107517721(PAICS)
MJV: 108395834
LAV: 100658417
TMU: 101346245
MDO: 100012535(PAICS)
SHR: 100923019(PAICS)
PCW: 110200170(PAICS)
OAA: 100086365
GGA: 396534(PAICS)
MGP: 100539860(PAICS)
CJO: 107313717(PAICS) 116653347
NMEL: 110398445
APLA: 101797218
ACYG: 106048608 106048610(PAICS)
TGU: 100225152(PAICS)
LSR: 110471777
SCAN: 103825290(PAICS) 103826194
GFR: 102043382 102043552(PAICS)
FAB: 101807763 101808142(PAICS)
PHI: 102111686(PAICS) 106628861
PMAJ: 107202963 107203210(PAICS)
CCAE: 111928008 111928009(PAICS)
CCW: 104690617(PAICS) 104690618
ETL: 114058312 114058315(PAICS)
FPG: 101919014(PAICS)
FCH: 102045839 102046009(PAICS)
CLV: 102085431 102094220(PAICS)
EGZ: 104129452
NNI: 104020782
ACUN: 113479039 113479040(PAICS)
AAM: 106490207(PAICS)
ASN: 102380243
AMJ: 102565809(PAICS)
PSS: 102446966(PAICS) 102447225
CMY: 102937919(PAICS)
CPIC: 101942651(PAICS)
ACS: 100566555(paics)
PVT: 110077009 110077010(PAICS)
PBI: 103060841(PAICS)
PMUR: 107297224(PAICS)
TSR: 106554316(PAICS) 106554752
PMUA: 114603707
GJA: 107123142(PAICS)
XLA: 379855(paics) 431975(paics.2.L) 444677(paics.1.S)
XTR: 100036662(paics.2) 100488155(paics.1)
NPR: 108794756(PAICS)
DRE: 321193(paics)
CCAR: 109113011
IPU: 108257759
PHYP: 113545223(paics)
AMEX: 103037884
EEE: 113586370
TRU: 101073764(paics)
LCO: 104919099(paics)
NCC: 104947087(paics)
OLA: 101171736(paics)
XMA: 102236450
XCO: 114151174(paics)
PRET: 103463823
CVG: 107091569
NFU: 107393397
KMR: 108243405
ALIM: 106534470
AOCE: 111569591(paics)
CSEM: 103376690(paics)
POV: 109646212(paics)
LCF: 108879073(paics)
SDU: 111226365(paics)
HCQ: 109532211(paics)
BPEC: 110154796(paics)
MALB: 109962065
ELS: 105011850
SFM: 108922797
PKI: 111834756(paics)
LCM: 102354332(PAICS)
CMK: 103178180(paics)
RTP: 109915470(paics)
CIN: 100177417
SPU: 575874
APLC: 110988626
DME: Dmel_CG3989(Paics)
DER: 6551233
DSI: Dsimw501_GD15919(Dsim_GD15919) Dsimw501_GD23841(Dsim_GD23841)
DYA: Dyak_GE16201(Dyak_ade5)
DSR: 110180572
DPE: 6599097
DMN: 108161668
DAZ: 108619905
DNV: 108656029
DHE: 111602405
DVI: 6633868
MDE: 101893760
LCQ: 111687676
AAG: 5578622
AME: 551966
BIM: 100749872
BTER: 100649872
CCAL: 108629228
OBB: 114879276
SOC: 105195586
MPHA: 105835135
AEC: 105144565
ACEP: 105618440
PBAR: 105431681
VEM: 105569749
HST: 105184394
DQU: 106746186
CFO: 105253371
LHU: 105673924
PGC: 109857193
OBO: 105278330
PCF: 106787577
NVI: 100122105
CSOL: 105364366
MDL: 103569558
TCA: 656066
DPA: 109546155
ATD: 109598511
NVL: 108561415
BMOR: 732910
BMAN: 114242655
PMAC: 106711899
HAW: 110379838
TNL: 113494584
API: 100169501
DNX: 107169969
AGS: 114121209
RMD: 113548300
CLEC: 106673658
ZNE: 110838439
FCD: 110857027
TUT: 107361566
DPTE: 113792963
CSCU: 111642214
PTEP: 107441412
CEL: CELE_B0286.3(paic-1)
CBR: CBG03675
TSP: Tsp_02239
CRG: 105333392
MYI: 110447155
OBI: 106881666
NVE: 5500615
EPA: 110243452
ADF: 107351950
AMIL: 114970396
PDAM: 113666335
SPIS: 111338988
DGT: 114527900
HMG: 100210246
DDI: DDB_G0283987(purC/E)
DFA: DFA_08571(purC/E)
 » show all
Reference
  Authors
O'Donnell AF, Tiong S, Nash D, Clark DV
  Title
The Drosophila melanogaster ade5 gene encodes a bifunctional enzyme for two steps in the de novo purine synthesis pathway.
  Journal
Genetics 154:1239-53 (2000)
  Sequence
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