KEGG   ORTHOLOGY: K01663
Entry
K01663                      KO                                     
Symbol
HIS7
Name
imidazole glycerol-phosphate synthase [EC:4.3.2.10]
Pathway
map00340  Histidine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
Module
M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    K01663  HIS7; imidazole glycerol-phosphate synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.3  Carbon-nitrogen lyases
   4.3.2  Amidine-lyases
    4.3.2.10  imidazole glycerol-phosphate synthase
     K01663  HIS7; imidazole glycerol-phosphate synthase
Other DBs
RN: R04558
COG: COG0118 COG0107
GO: 0000107
Genes
LCQ: 111690040
MMER: 123544566
NVE: 5505657
PDAM: 113668256
SPIS: 111325806
ATH: AT4G26900(AT-HF)
ALY: 9303608
CRB: 17881013
CSAT: 104717543 104722242 104730701
EUS: EUTSA_v10024744mg
RSZ: 108842888
THJ: 104811618
CIT: 102621956
PVY: 116143242
TCC: 18588725
GRA: 105802444
GAB: 108473730
EGR: 104448212
VRA: 106780151
VAR: 108321945
VUN: 114187760
CCAJ: 109811300
APRC: 113854570
MTR: 25488966
CAM: 101495130
PSAT: 127084895
LJA: Lj0g3v0058939.1(Lj0g3v0058939.1) Lj0g3v0058939.2(Lj0g3v0058939.2) Lj4g3v0014330.1(Lj4g3v0014330.1)
ADU: 107496365
AIP: 107608757
LANG: 109361172
FVE: 101293002
RCN: 112203973
PPER: 18779915
PMUM: 103326425
PAVI: 110752842
PDUL: 117626510
PXB: 103951387
ZJU: 107432630
MNT: 21391460
CSV: 101205184
CMO: 103490133
BHJ: 120085814
MCHA: 111010464
RCU: 8266248
JCU: 105632985
MESC: 110612383
JRE: 108984361
QLO: 115957358
TWL: 119985938
VVI: 100262276
VRI: 117909439
SLY: 101268295
SPEN: 107026296
SOT: 102604045
SSTN: 125876081
CANN: 107878743
NSY: 104224117
NTO: 104100130
NAU: 109238818
ITR: 116011084
SIND: 105176677
EGT: 105968943
SSPL: 121774928
ECAD: 122611066
CCAV: 112504455
DCR: 108192806
CSIN: 114271963
BVG: 104897872
NNU: 104600724
MING: 122066947
TSS: 122642884
NCOL: 116266099
OSA: 4332296
DOSA: Os03t0256400-01(Os03g0256400)
OBR: 102714439
BDI: 100830050
ATS: 109780595
TUA: 125552354
SBI: 8054317
SITA: 101781742
SVS: 117837720
PHAI: 112875382
PDA: 103715056
EGU: 105060331
MUS: 103996883
DCT: 110108423
PEQ: 110018207
AOF: 109819570
ATR: 18447237
PPP: 112291012
APRO: F751_6318
SCE: YBR248C(HIS7)
SEUB: DI49_1272
ERC: Ecym_2250
KMX: KLMA_20413(HIS7)
NCS: NCAS_0H01160(NCAS0H01160)
NDI: NDAI_0F02140(NDAI0F02140)
TPF: TPHA_0J02100(TPHA0J02100)
TDL: TDEL_0B03860(TDEL0B03860)
KAF: KAFR_0G03620(KAFR0G03620)
KNG: KNAG_0M00520(KNAG0M00520)
PIC: PICST_65481(HIS7)
CAL: CAALFM_C703720CA(HIS7)
CDU: CD36_73390(HIS7)
SLB: AWJ20_329(HIS7)
BNN: FOA43_002005(HIS7)
BBRX: BRETT_004013(HIS7)
NCR: NCU07156(his-6)
NTE: NEUTE1DRAFT74784(NEUTE1DRAFT_74784)
MGR: MGG_00253
SSCK: SPSK_09025
MAW: MAC_02594
MAJ: MAA_03044
CMT: CCM_04678
BFU: BCIN_09g02000(Bchis7)
MBE: MBM_08882
ANI: AN7430.2
ANG: ANI_1_2066024(An02g14890)
ALUC: AKAW2_11247S(HIS7)
ACHE: ACHE_80234S(HIS7)
APUU: APUU_80620S(HIS7)
ABE: ARB_02630
TVE: TRV_03046
PTE: PTT_13691
SPO: SPBC418.01c(his4)
CNE: CNA07220
CNB: CNBA7020
TASA: A1Q1_06985
ABP: AGABI1DRAFT66258(AGABI1DRAFT_66258)
ABV: AGABI2DRAFT215018(AGABI2DRAFT_215018)
SCM: SCHCO_02612243(SCHCODRAFT_02612243)
MGL: MGL_0140
MRT: MRET_1178
SMIN: v1.2.010568.t1(symbB.v1.2.010568.t1)
TPS: THAPSDRAFT_30478(hisH)
SPAR: SPRG_00441
ATEP: Atep_13830
TTP: E6P07_07595(hisF)
THIP: N838_09350
CJAP: GWK36_11175(hisF)
THIM: KFB96_02470(hisF)
TBOG: LT988_24050(hisF)
DPS: DP2167
DSF: UWK_03250
DOG: HP555_13735(hisF)
DML: Dmul_08250(hisHF)
DTO: TOL2_C40970(hisHF)
DALK: DSCA_04360
DAX: FDQ92_14055(hisF)
TMAI: FVE67_08195(hisF)
 » show all
Reference
PMID:8366040
  Authors
Kuenzler M, Balmelli T, Egli CM, Paravicini G, Braus GH
  Title
Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae.
  Journal
J Bacteriol 175:5548-58 (1993)
DOI:10.1128/JB.175.17.5548-5558.1993
Reference
  Authors
Chaudhuri BN, Lange SC, Myers RS, Davisson VJ, Smith JL
  Title
Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex  and the free enzyme.
  Journal
Biochemistry 42:7003-12 (2003)
DOI:10.1021/bi034320h
  Sequence
[sce:YBR248C]
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