KEGG   ORTHOLOGY: K01705
Entry
K01705                      KO                                     

Name
LYS4
Definition
homoaconitate hydratase [EC:4.2.1.36]
Pathway
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K01705  LYS4; homoaconitate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.36  homoaconitate hydratase
     K01705  LYS4; homoaconitate hydratase
Other DBs
RN: R04371
COG: COG1048
GO: 0004409
Genes
QSU: 112018819 112023082
SCE: YDR234W(LYS4)
AGO: AGOS_ABL106C
ERC: Ecym_5123
KLA: KLLA0_C15125g
KMX: KLMA_30527(LYS4)
LTH: KLTH0E10582g
VPO: Kpol_1031p57
ZRO: ZYRO0A10076g
CGR: CAGL0K10978g
NCS: NCAS_0B02660(NCAS0B02660)
NDI: NDAI_0C05030(NDAI0C05030)
TPF: TPHA_0L01150(TPHA0L01150)
TBL: TBLA_0A01460(TBLA0A01460)
TDL: TDEL_0B01800(TDEL0B01800)
KAF: KAFR_0E02730(KAFR0E02730)
PIC: PICST_88705(LYS4)
SPAA: SPAPADRAFT_58782(LYS4)
CAL: CAALFM_C404410CA(LYS4)
SLB: AWJ20_348(LYS4)
NCR: NCU08898(lys-6)
NTE: NEUTE1DRAFT58933(NEUTE1DRAFT_58933)
MGR: MGG_04842
SSCK: SPSK_03952
CMT: CCM_07793
BFU: BCIN_14g00430(Bclys4)
MBE: MBM_05638
ANI: AN6521.2
ANG: ANI_1_1106134(An15g00350)
ABE: ARB_04155
TVE: TRV_03936
PNO: SNOG_01131(SNOG_01129 SNOG_01130)
PTE: PTT_19520
SPO: SPAC343.16(lys2)
CNE: CNK00580
CNB: CNBK2910
TASA: A1Q1_04925
ABP: AGABI1DRAFT59676(AGABI1DRAFT_59676)
ABV: AGABI2DRAFT184036(AGABI2DRAFT_184036)
MGL: MGL_3298
MRT: MRET_2395
SPAR: SPRG_03993
IAL: IALB_1150
MRO: MROS_2220
CABY: Cabys_582
 » show all
Reference
  Authors
Fazius F, Shelest E, Gebhardt P, Brock M
  Title
The fungal alpha-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate.
  Journal
Mol Microbiol 86:1508-30 (2012)
DOI:10.1111/mmi.12076
  Sequence
[sce:YDR234W]
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