KEGG   ORTHOLOGY: K01948Help
Entry
K01948                      KO                                     

Name
CPS1
Definition
carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
Pathway
ko00220  Arginine biosynthesis
ko00250  Alanine, aspartate and glutamate metabolism
ko00910  Nitrogen metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
ko01230  Biosynthesis of amino acids
Module
M00029  Urea cycle
Disease
H00164  Carbamoyl phosphate synthetase I deficiency
H01398  Primary hyperammonemic disorders (Urea cycle disorders)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00910 Nitrogen metabolism
    K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
   00220 Arginine biosynthesis
    K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.16  carbamoyl-phosphate synthase (ammonia)
     K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   K01948  CPS1; carbamoyl-phosphate synthase (ammonia)
BRITE hierarchy
Other DBs
RN: R00149
GO: 0004087
Genes
HSA: 1373(CPS1)
PTR: 738670(CPS1)
PPS: 100984596(CPS1)
GGO: 101130709(CPS1)
PON: 100442727(CPS1)
NLE: 100596216(CPS1)
MCC: 711806(CPS1)
MCF: 102139369(CPS1)
CSAB: 103217763(CPS1)
RRO: 104655495(CPS1)
RBB: 108540334(CPS1)
CJC: 100402602(CPS1)
SBQ: 101050943(CPS1)
MMU: 227231(Cps1)
MCAL: 110289777(Cps1)
MPAH: 110322614(Cps1)
RNO: 497840(Cps1)
CGE: 100760467(Cps1)
NGI: 103744467(Cps1)
HGL: 101696508(Cps1)
CCAN: 109699651(Cps1)
OCU: 100303765(CPS1)
TUP: 102491899(CPS1)
CFA: 488506(CPS1)
VVP: 112922588(CPS1)
AML: 100466842(CPS1)
UMR: 103659822(CPS1)
UAH: 113250504(CPS1)
ORO: 101371212(CPS1)
FCA: 101099824(CPS1)
PTG: 102968283(CPS1)
AJU: 106984775(CPS1)
BTA: 510506(CPS1)
BOM: 102267831(CPS1)
BIU: 109570387(CPS1)
BBUB: 102415970(CPS1)
PHD: 102342950(CPS1)
CHX: 102179612(CPS1)
OAS: 101107584(CPS1)
SSC: 100157716(CPS1)
CFR: 102516394(CPS1) 102522395
CDK: 105101586(CPS1)
BACU: 103003987(CPS1)
LVE: 103079188(CPS1)
OOR: 101279675(CPS1)
DLE: 111171789(CPS1)
PCAD: 102973240(CPS1)
ECB: 100050116(CPS1)
EPZ: 103554808(CPS1)
EAI: 106843053(CPS1)
MYB: 102262103(CPS1)
MYD: 102756563(CPS1)
MNA: 107524839(CPS1)
HAI: 109390430(CPS1)
RSS: 109445055(CPS1)
DRO: 112307671(CPS1)
PALE: 102895317(CPS1)
RAY: 107517643(CPS1)
LAV: 100669826(CPS1)
TMU: 101359193
MDO: 100015090(CPS1)
SHR: 100929825(CPS1)
PCW: 110223299(CPS1)
OAA: 100077228(CPS1)
GGA: 428994(CPS1)
MGP: 100539661(CPS1)
CJO: 107316483(CPS1)
NMEL: 110399288(CPS1)
APLA: 101797791(CPS1)
ACYG: 106034508(CPS1)
TGU: 100221389(CPS1)
LSR: 110471694(CPS1)
SCAN: 103814751(CPS1)
GFR: 102044867(CPS1)
FAB: 101816308(CPS1)
PHI: 102105821(CPS1)
PMAJ: 107207199(CPS1)
CCAE: 111931881(CPS1)
CCW: 104694540(CPS1)
ETL: 114059416(CPS1)
FPG: 101910440(CPS1)
FCH: 102046837(CPS1)
CLV: 102091543(CPS1)
EGZ: 104124302(CPS1)
NNI: 104009921(CPS1)
ACUN: 113482015(CPS1)
PADL: 103921645(CPS1)
AAM: 106492382(CPS1)
ASN: 102386005(CPS1)
AMJ: 106736782(CPS1)
PSS: 102462440(CPS1)
CMY: 102943091(CPS1)
CPIC: 101942404(CPS1)
ACS: 100562333(cps1)
PVT: 110072386(CPS1)
PBI: 103061484(CPS1)
PMUR: 107301875(CPS1)
XLA: 733340(cps1.L)
XTR: 100158506(cps1)
NPR: 108794421(CPS1) 108802193
DRE: 555623(cps1)
SRX: 107741925
SANH: 107660611
IPU: 108266807(cps1)
PHYP: 113526109(cps1)
AMEX: 103026142(cps1)
EEE: 113589154(cps1)
TRU: 101074466(cps1)
LCO: 104929821(cps1)
NCC: 104943734 104953308(cps1)
MZE: 101479159(cps1)
OLA: 101164854(cps1)
XMA: 102232024(cps1)
XCO: 114147479(cps1)
PRET: 103461545(cps1)
NFU: 107396242(cps1)
KMR: 108240446(cps1)
AOCE: 111584991(cps1) 111585025
CSEM: 103392237(cps1)
POV: 109631134(cps1)
LCF: 108885731 108892757(cps1)
SDU: 111218322(cps1)
HCQ: 109531202(cps1)
BPEC: 110156044(cps1)
SASA: 106586447(cps1)
OTW: 112238893(cps1)
SALP: 112068953(cps1)
ELS: 105008497(cps1)
SFM: 108922278(cps1)
LCM: 102363877(CPS1)
CMK: 103182939(cps1)
SPU: 584369
APLC: 110989285
SKO: 100367850
PCAN: 112558598
OBI: 106879763
EPA: 110246605
PDAM: 113673921
SPIS: 111323363
FCY: FRACYDRAFT_169332(Fc_169332)
AAF: AURANDRAFT_20552(CPS1)
SPAR: SPRG_05438
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1840546
  Authors
Haraguchi Y, Uchino T, Takiguchi M, Endo F, Mori M, Matsuda I
  Title
Cloning and sequence of a cDNA encoding human carbamyl phosphate synthetase I: molecular analysis of hyperammonemia.
  Journal
Gene 107:335-40 (1991)
DOI:10.1016/0378-1119(91)90336-A
LinkDB All DBs

KEGG   REACTION: R00149Help
Entry
R00149                      Reaction                               

Name
Carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating)
Definition
2 ATP + Ammonia + CO2 + H2O <=> 2 ADP + Orthophosphate + Carbamoyl phosphate
Equation
Reaction class
RC00002  C00002_C00008
RC02804  C00014_C00169
Enzyme
Pathway
rn00220  Arginine biosynthesis
rn00250  Alanine, aspartate and glutamate metabolism
rn00910  Nitrogen metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01230  Biosynthesis of amino acids
Module
M00029  Urea cycle
Orthology
K01948  carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16]
Other DBs
RHEA: 10627
LinkDB All DBs

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