K02187                      KO                                     

caspase 3 [EC:]
ko01524  Platinum drug resistance
ko04010  MAPK signaling pathway
ko04115  p53 signaling pathway
ko04210  Apoptosis
ko04215  Apoptosis - multiple species
ko04650  Natural killer cell mediated cytotoxicity
ko04657  IL-17 signaling pathway
ko04668  TNF signaling pathway
ko04726  Serotonergic synapse
ko04932  Non-alcoholic fatty liver disease
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05016  Huntington disease
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05130  Pathogenic Escherichia coli infection
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05210  Colorectal cancer
ko05222  Small cell lung cancer
ko05416  Viral myocarditis
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K02187  CASP3; caspase 3
   04668 TNF signaling pathway
    K02187  CASP3; caspase 3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K02187  CASP3; caspase 3
   04215 Apoptosis - multiple species
    K02187  CASP3; caspase 3
   04115 p53 signaling pathway
    K02187  CASP3; caspase 3
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K02187  CASP3; caspase 3
   04657 IL-17 signaling pathway
    K02187  CASP3; caspase 3
  09156 Nervous system
   04726 Serotonergic synapse
    K02187  CASP3; caspase 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02187  CASP3; caspase 3
   05206 MicroRNAs in cancer
    K02187  CASP3; caspase 3
   05205 Proteoglycans in cancer
    K02187  CASP3; caspase 3
   05203 Viral carcinogenesis
    K02187  CASP3; caspase 3
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02187  CASP3; caspase 3
   05222 Small cell lung cancer
    K02187  CASP3; caspase 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02187  CASP3; caspase 3
   05012 Parkinson disease
    K02187  CASP3; caspase 3
   05014 Amyotrophic lateral sclerosis
    K02187  CASP3; caspase 3
   05016 Huntington disease
    K02187  CASP3; caspase 3
   05020 Prion disease
    K02187  CASP3; caspase 3
   05022 Pathways of neurodegeneration - multiple diseases
    K02187  CASP3; caspase 3
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K02187  CASP3; caspase 3
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K02187  CASP3; caspase 3
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02187  CASP3; caspase 3
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K02187  CASP3; caspase 3
   05130 Pathogenic Escherichia coli infection
    K02187  CASP3; caspase 3
   05132 Salmonella infection
    K02187  CASP3; caspase 3
   05133 Pertussis
    K02187  CASP3; caspase 3
   05134 Legionellosis
    K02187  CASP3; caspase 3
   05152 Tuberculosis
    K02187  CASP3; caspase 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K02187  CASP3; caspase 3
   05162 Measles
    K02187  CASP3; caspase 3
   05164 Influenza A
    K02187  CASP3; caspase 3
   05161 Hepatitis B
    K02187  CASP3; caspase 3
   05160 Hepatitis C
    K02187  CASP3; caspase 3
   05168 Herpes simplex virus 1 infection
    K02187  CASP3; caspase 3
   05163 Human cytomegalovirus infection
    K02187  CASP3; caspase 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02187  CASP3; caspase 3
   05169 Epstein-Barr virus infection
    K02187  CASP3; caspase 3
   05165 Human papillomavirus infection
    K02187  CASP3; caspase 3
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K02187  CASP3; caspase 3
   05145 Toxoplasmosis
    K02187  CASP3; caspase 3
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K02187  CASP3; caspase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K02187  CASP3; caspase 3
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases  caspase-3
     K02187  CASP3; caspase 3
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C14: caspase family
   K02187  CASP3; caspase 3
Other DBs
GO: 0097200
HSA: 836(CASP3)
PTR: 461669(CASP3)
PPS: 100974934(CASP3)
GGO: 101126742(CASP3)
PON: 100435491(CASP3)
NLE: 100585064(CASP3)
MCC: 694473(CASP3)
MCF: 102144182(CASP3)
CSAB: 103236614(CASP3)
RRO: 104666783 104673791(CASP3)
RBB: 108512689
CJC: 100387570(CASP3)
SBQ: 101029697(CASP3)
MMU: 12367(Casp3)
MCAL: 110299851(Casp3)
MPAH: 110336608(Casp3)
RNO: 25402(Casp3)
CGE: 100689061(Casp3)
NGI: 103744668 103750475(Casp3)
OCU: 100008840(CASP3)
TUP: 102472926(CASP3) 102487119
CFA: 403567(CASP3)
VVP: 112934766(CASP3)
AML: 100469056(CASP3)
UMR: 103680991(CASP3)
UAH: 113262259(CASP3)
ORO: 101371336(CASP3)
ELK: 111144607
FCA: 493932(CASP3)
PTG: 102954729(CASP3)
PPAD: 109251018(CASP3)
AJU: 106979326(CASP3)
BTA: 408016(CASP3)
BOM: 102287348(CASP3)
BIU: 109553316(CASP3)
BBUB: 102415768(CASP3)
CHX: 102177031(CASP3)
OAS: 114116869 443031(CASP3)
SSC: 397244(CASP3)
CFR: 102520133(CASP3)
CDK: 105084433(CASP3)
BACU: 103019939(CASP3)
LVE: 103073819(CASP3)
OOR: 101289847(CASP3)
DLE: 111173401(CASP3)
PCAD: 102975528 102977692(CASP3)
ECB: 100034083(CASP3)
EPZ: 103549132(CASP3)
EAI: 106830081(CASP3)
MYB: 102258599(CASP3)
MYD: 102760961(CASP3)
MNA: 107535740(CASP3)
HAI: 109395706(CASP3)
DRO: 112306749(CASP3)
PALE: 102897289(CASP3)
RAY: 107510456(CASP3)
MJV: 108389793(CASP3)
LAV: 100672256(CASP3)
TMU: 101354307
MDO: 654273(CASP3) 654275
SHR: 100922500(CASP3) 100922757
PCW: 110222594(CASP3)
OAA: 100087105(CASP3)
GGA: 395476(CASP3)
MGP: 100548182(CASP3)
CJO: 107313280(CASP3)
NMEL: 110397291(CASP3)
APLA: 101805296(CASP3)
ACYG: 106035172(CASP3)
TGU: 100230799(CASP3)
LSR: 110477516(CASP3)
SCAN: 103825669(CASP3)
GFR: 102035830(CASP3)
FAB: 101808212(CASP3)
PHI: 102104322(CASP3)
PMAJ: 107203069(CASP3)
CCAE: 111945572(CASP3)
CCW: 104690575(CASP3)
ETL: 114055579(CASP3)
FPG: 101913355(CASP3) 101922533
FCH: 102050683 102056397(CASP3)
CLV: 102089427(CASP3)
EGZ: 104129473(CASP3)
NNI: 104021286(CASP3)
ACUN: 113479376(CASP3)
PADL: 103922530(CASP3) 103926227
AAM: 106484082(CASP3)
ASN: 102369935 102383553(CASP3)
AMJ: 102572621(CASP3) 102576234(CASP14)
PSS: 102463409
CMY: 102942062(CASP3)
CPIC: 101948246(CASP3)
ACS: 100563931(casp3)
PVT: 110083865(CASP3)
PBI: 103049711(CASP3)
PMUR: 107302670(CASP3)
TSR: 106539846(CASP3)
PMUA: 114585959 114604250(CASP3)
GJA: 107115654(CASP3)
XLA: 100036910(casp3.L) 397720(casp3.S)
XTR: 100151728(casp3.2) 100486222(casp3.1)
DRE: 140621(casp3a) 566604(casp3b)
IPU: 100528811(casp3) 108260860
EEE: 113581517(casp3) 113586537
TRU: 446083(casp3)
LCO: 104928227 104936945(caspase-3)
NCC: 104959742 104967108(casp3)
OLA: 100049215(casp3) 100049265
XCO: 114139499 114144355(casp3)
CVG: 107090480 107094160(casp3)
NFU: 107390752(casp3) 107397381
CSEM: 103383467 103391460(casp3)
MALB: 109957512(casp3) 109972113
SASA: 100194892(casp3) 106602722(CASP3) 106612018
ELS: 105006735(casp3) 105029385(casp3)
SFM: 108924572(casp3) 114912449
PKI: 111853593(casp3)
LCM: 106705928(CASP3)
CMK: 103187405(casp3) 103190313
APLC: 110975794
DPE: 113565090
DMN: 108158700
DHE: 111592184
MDE: 101899570
LCQ: 111676405
AAG: 5567300
PVM: 113829172
MYI: 110452312
LAK: 106173180
SHX: MS3_07622
EGL: EGR_04745
NVE: 5502486
EPA: 110247107
 » show all
Fernandes-Alnemri T, Litwack G, Alnemri ES
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.
J Biol Chem 269:30761-4 (1994)
Brentnall M, Rodriguez-Menocal L, De Guevara RL, Cepero E, Boise LH
Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis.
BMC Cell Biol 14:32 (2013)

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