KEGG   ORTHOLOGY: K02318
Entry
K02318                      KO                                     

Name
COASY
Definition
phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]
Pathway
ko00770  Pantothenate and CoA biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00120  Coenzyme A biosynthesis, pantothenate => CoA
Disease
H00833  Neurodegeneration with brain iron accumulation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.24  dephospho-CoA kinase
     K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase
   2.7.7  Nucleotidyltransferases
    2.7.7.3  pantetheine-phosphate adenylyltransferase
     K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Other mitophagy factors
    K02318  COASY; phosphopantetheine adenylyltransferase / dephospho-CoA kinase
Other DBs
RN: R00130 R03035
GO: 0004595 0004140
Genes
HSA: 80347(COASY)
PTR: 454690(COASY)
PPS: 100991461(COASY)
GGO: 101151903(COASY)
PON: 100456097(COASY)
NLE: 100600459(COASY)
MCC: 710491(COASY)
MCF: 102124775(COASY)
CSAB: 103243403(COASY)
RRO: 104680238(COASY)
RBB: 108518329(COASY)
CJC: 100409362(COASY)
SBQ: 101039046(COASY)
MMU: 71743(Coasy)
MCAL: 110305492(Coasy)
MPAH: 110331632(Coasy)
RNO: 287711(Coasy)
MUN: 110550914(Coasy)
CGE: 100757898(Coasy)
NGI: 103735902(Coasy)
HGL: 101718395(Coasy)
CCAN: 109687307(Coasy)
OCU: 100344683(COASY)
TUP: 102494262(COASY)
CFA: 480517(COASY)
VVP: 112910766(COASY)
AML: 100479996(COASY)
UMR: 103672577(COASY)
UAH: 113265414(COASY)
ORO: 101375788(COASY)
ELK: 111151242
FCA: 101091667(COASY)
PTG: 102959694(COASY)
PPAD: 109258567(COASY)
AJU: 106972612(COASY)
BTA: 614728(COASY)
BOM: 102280791(COASY)
BIU: 109553164 109574082(COASY)
BBUB: 102412358(COASY)
CHX: 102187624(COASY)
OAS: 101102655(COASY)
SSC: 396688(COASY)
CFR: 102518963(COASY)
CDK: 105090464(COASY)
LVE: 103070347(COASY)
OOR: 101283706(COASY)
DLE: 111166389(COASY)
PCAD: 102974646(COASY)
ECB: 100066023(COASY)
EPZ: 103550361(COASY)
EAI: 106826276(COASY)
MYB: 102261991(COASY)
MYD: 102753266(COASY)
MNA: 107528867(COASY)
HAI: 109395775(COASY)
DRO: 112298565(COASY)
PALE: 102882271(COASY)
RAY: 107513829(COASY)
MJV: 108386061(COASY)
LAV: 100673299(COASY)
TMU: 101353624
MDO: 100011732(COASY)
SHR: 100933060(COASY)
PCW: 110198394(COASY)
OAA: 100680675(COASY)
MGP: 100549752(COASY)
NMEL: 110388419(COASY)
ACYG: 106047994(COASY)
TGU: 101233652(COASY)
LSR: 110471885(COASY)
SCAN: 103821708(COASY)
GFR: 102042995(COASY)
FAB: 101819981(COASY)
PHI: 102100635(COASY)
PMAJ: 107215089(COASY)
CCAE: 111945936(COASY)
CCW: 104697816(COASY)
ETL: 114063615(COASY)
FPG: 101919756(COASY)
FCH: 102049823(COASY)
CLV: 102098259(COASY)
EGZ: 104135071(COASY)
NNI: 104009929(MLX)
PADL: 103920531(COASY)
AAM: 106491089
ASN: 102382044(COASY)
AMJ: 102565422(COASY)
PSS: 102462841(COASY)
CMY: 102934092(COASY)
CPIC: 101934771(COASY)
ACS: 100567142(coasy)
PVT: 110074872(COASY)
PBI: 103048219(COASY)
PMUR: 107282647(COASY)
TSR: 106541159(COASY)
PMUA: 114581930(COASY)
GJA: 107111463(COASY)
XLA: 444569(coasy.L)
XTR: 100490454(coasy)
NPR: 108799037(COASY)
DRE: 447838(coasy)
SRX: 107718069 107732065(coasy)
SGH: 107554408 107599685(coasy)
IPU: 108264103(coasy)
PHYP: 113533963(coasy)
AMEX: 103045691(coasy)
EEE: 113583783(coasy)
TRU: 101061926(coasy)
LCO: 104932149(coasy)
NCC: 104943459(coasy)
MZE: 101470739(coasy)
ONL: 100703514(coasy)
OLA: 101173746(coasy)
XMA: 102228936(coasy)
XCO: 114152073(coasy)
PRET: 103481491(coasy)
CVG: 107088805(coasy)
NFU: 107387567(coasy)
KMR: 108249049(coasy)
ALIM: 106516999(coasy)
AOCE: 111579055(coasy)
CSEM: 103381493(coasy)
POV: 109626964(coasy)
LCF: 108901723(coasy)
SDU: 111220054(coasy)
SLAL: 111657115(coasy)
HCQ: 109513396(coasy)
BPEC: 110154307(coasy)
MALB: 109963087(coasy)
SASA: 106579131(coasy)
OTW: 112223789(coasy)
SALP: 111978503(coasy)
ELS: 105028460(coasy)
SFM: 108928136(coasy)
PKI: 111842569(coasy)
LCM: 102362220(COASY)
CMK: 103183806(coasy)
RTP: 109929557
BFO: 118424050
CIN: 100184845
APLC: 110989257
SKO: 100370768
DME: Dmel_CG10575(Ppat-Dpck)
DER: 6544694
DSE: 6610912
DSI: Dsimw501_GD17598(Dsim_GD17598)
DAN: 6493318
DSR: 110176223
DPE: 6602834
DMN: 108152541
DWI: 6638805
DAZ: 108612496
DNV: 108650367
DHE: 111595307
DVI: 6622234
MDE: 101887329
LCQ: 111682123
AAG: 5578935
AME: 552104
BIM: 100748083
BTER: 100643894
CCAL: 108629667
OBB: 114874632
SOC: 105208094
MPHA: 105837422
AEC: 105154638
ACEP: 105622466
PBAR: 105432205
VEM: 105560034
HST: 105183106
DQU: 106742644
CFO: 105257058
LHU: 105673684
PGC: 109853663
OBO: 105285675
PCF: 106784867
NVI: 100116195
CSOL: 105359654
MDL: 103570858
TCA: 664060
DPA: 109545265
ATD: 109598236
NVL: 108559308
BMOR: 101738185
BMAN: 114251317
PMAC: 106717784
PRAP: 110997005
HAW: 110372838
TNL: 113499988
API: 100159484
DNX: 107162179
AGS: 114128278
RMD: 113559140
BTAB: 109039622
CLEC: 106668106
ZNE: 110839853
FCD: 110852486
PVM: 113827249
TUT: 107366287
DPTE: 113798496
CSCU: 111631592
CEL: CELE_Y65B4A.8(Y65B4A.8)
BMY: Bm1_41820
TSP: Tsp_08941
PCAN: 112565370
CRG: 105324980
MYI: 110458809
OBI: 106882755
LAK: 106152114
SHX: MS3_01635
EGL: EGR_09146
NVE: 5504992
EPA: 110235108
ADF: 107334607
AMIL: 114968141
PDAM: 113677993
SPIS: 111333094
DGT: 114517787
HMG: 100209839
AQU: 105314234
 » show all
Reference
  Authors
Daugherty M, Polanuyer B, Farrell M, Scholle M, Lykidis A, de Crecy-Lagard V, Osterman A
  Title
Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.
  Journal
J Biol Chem 277:21431-9 (2002)
DOI:10.1074/jbc.M201708200
  Sequence
[hsa:80347]
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