KEGG ORTHOLOGY: K02326

ORTHOLOGY: K02326

Entry

K02326 KO

Name

POLE3

Definition

DNA polymerase epsilon subunit 3 [EC:2.7.7.7]

Pathway

ko03030

DNA replication

ko03410

Base excision repair

ko03420

Nucleotide excision repair

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03410 Base excision repair
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03420 Nucleotide excision repair
    K02326  POLE3; DNA polymerase epsilon subunit 3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03036 Chromosome and associated proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
   03400 DNA repair and recombination proteins
    K02326  POLE3; DNA polymerase epsilon subunit 3
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02326  POLE3; DNA polymerase epsilon subunit 3
DNA replication proteins [BR:ko03032]
Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    K02326  POLE3; DNA polymerase epsilon subunit 3
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Chromatin remodeling factors
   CHRAC complex
    K02326  POLE3; DNA polymerase epsilon subunit 3
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      K02326  POLE3; DNA polymerase epsilon subunit 3

Other DBs

GO:

0003887

Genes

HSA:	54107(POLE3)

PTR:	741748(POLE3)

PPS:	100971005(POLE3)

GGO:	101130047(POLE3)

PON:	100173898(POLE3)

NLE:	100592542(POLE3)

MCC:	705074(POLE3)

MCF:	101867371(POLE3)

CSAB:

103218985(POLE3)

RRO:	104667876(POLE3)

RBB:	108532151(POLE3)

CJC:	100394191(POLE3)

SBQ:	101053500(POLE3)

MMU:	59001(Pole3)

MCAL:

110292744(Pole3)

MPAH:

110323429(Pole3)

RNO:	100362333 298098(Pole3)

MUN:	110555564(Pole3)

CGE:	100752018(Pole3)

NGI:	103734520(Pole3)

HGL:	101701491(Pole3)

CCAN:

109684092(Pole3)

OCU:	100355895(POLE3)

TUP:	102483842(POLE3)

CFA:	612550(POLE3)

VVP:	112923084(POLE3)

AML:	100475622(POLE3)

UMR:	103678602(POLE3)

UAH:	113266321(POLE3)

ORO:	101363489(POLE3)

ELK:

111145676

FCA:	101097106(POLE3)

PTG:	102953930(POLE3)

PPAD:

109269945(POLE3)

AJU:	106978405(POLE3)

BTA:	510678(POLE3)

BOM:	102277795(POLE3)

BIU:	109563372(POLE3)

BBUB:

102390329(POLE3)

CHX:	102173090(POLE3)

OAS:	101106138(POLE3)

SSC:	100517450(POLE3)

CFR:	102515759(POLE3)

CDK:	105103758(POLE3)

BACU:

102998240(POLE3)

LVE:	103082643(POLE3)

OOR:	101288980(POLE3)

DLE:	111177300(POLE3)

PCAD:

102976987(POLE3)

ECB:	100050165(POLE3)

EPZ:	103554126(POLE3)

EAI:	106822721(POLE3)

MYB:	102247548(POLE3)

MYD:	102771370(POLE3)

MNA:	107535583(POLE3)

HAI:	109379317(POLE3)

DRO:	112306472(POLE3)

PALE:

102880775(POLE3)

RAY:	107500761(POLE3)

MJV:	108390095(POLE3)

LAV:	104845639(POLE3)

TMU:

101358563

MDO:	100010006(POLE3)

SHR:	100926444(POLE3)

PCW:	110193616(POLE3)

OAA:	114811227(POLE3)

GGA:	417275(POLE3)

MGP:	100549999(POLE3)

CJO:	107321601(POLE3)

NMEL:

110406875(POLE3)

APLA:

101797381(POLE3)

ACYG:

106037147(POLE3)

TGU:	100228225(POLE3)

LSR:	110472209(POLE3)

SCAN:

103819075(POLE3)

GFR:	102034234(POLE3)

FAB:	101819577(POLE3)

PHI:	102110275(POLE3)

PMAJ:

107211908(POLE3)

CCAE:

111936908(POLE3)

CCW:	104688426(POLE3)

ETL:	114069910(POLE3)

FPG:	101914209(POLE3)

FCH:	102046667(POLE3)

EGZ:	104124031(POLE3)

NNI:	104022693(POLE3)

ACUN:

113486569(POLE3)

PADL:

103918963(POLE3)

AAM:	106487017(POLE3)

ASN:	102374888(POLE3)

AMJ:	102560165(POLE3)

PSS:	102452418(POLE3)

CMY:	102933347(POLE3)

CPIC:

101934894(POLE3)

PVT:	110087439(POLE3)

PBI:	103067387(POLE3)

PMUR:

107302552(POLE3)

TSR:	106548828(POLE3)

PMUA:

114590083(POLE3)

GJA:	107120422(POLE3)

XLA:	407748(pole3.L)

XTR:	550018(pole3)

NPR:	108789368(POLE3)

DRE:	393774(pole3)

SRX:	107723347(pole3) 107740970

SANH:

107691032 107693859

SGH:	107587393 107597112

IPU:	108260448(pole3)

PHYP:

113531087(pole3)

AMEX:

103024896(pole3)

EEE:	113570179(pole3)

TRU:	101066885(pole3)

TNG:	GSTEN00005214G001

LCO:	104937791(pole3)

MZE:	101472104(pole3)

ONL:	100698369(pole3)

OLA:	101172142(pole3)

XMA:	102217293(pole3)

XCO:	114143694(pole3)

PRET:

103460098(pole3) 103460110

CVG:	107085056(pole3)

NFU:	107381530(pole3)

KMR:	108250519(pole3)

ALIM:

106534195(pole3)

AOCE:

111578631(pole3)

CSEM:

103378878(pole3)

POV:	109644822(pole3)

LCF:	108894290(pole3)

SDU:	111223686(pole3)

SLAL:

111656624(pole3)

HCQ:	109514459(pole3)

BPEC:

110168044(pole3)

MALB:

109951252(pole3)

SASA:

100286640(pole3)

OTW:	112220048(pole3)

SALP:

112080629(pole3)

ELS:	105021784(pole3)

SFM:	108922695(pole3)

PKI:	111836256(pole3)

LCM:	102367039(POLE3)

CMK:	103182977(pole3)

RTP:	109915148(pole3)

BFO:	BRAFLDRAFT_271015

CIN:	100169885(cbf-2)

SPU:

580013

APLC:

110976322

SKO:

100378375

DME:	Dmel_CG13399(Chrac-14)

DER:

6540680

DSE:	Dsec_GM16944

DSI:	Dsimw501_GD23542(Dsim_GD23542)

DYA:	Dyak_GE18772(Dyak_Chrac-14)

DAN:	Dana_GF15525

DSR:

110183842

DPO:	Dpse_GA17216

DPE:	6593533 6604588

DMN:

108162336

DWI:

6651870

DGR:	Dgri_GH10953

DMO:	Dmoj_GI10366

DAZ:

108609786

DNV:

108649813

DHE:

111603960

DVI:	Dvir_GJ18023

MDE:

101888159

LCQ:

111688384

AGA:	AgaP_AGAP005051 AgaP_AGAP012825

AAG:

5572267

AALB:

109431639 115267496

CQU:	CpipJ_CPIJ016568 CpipJ_CPIJ020000

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

NVI:

CSOL:

MDL:

TCA:

DPA:

ATD:

NVL:

BMOR:

BMAN:

DPL:	KGM_205529

PMAC:

PRAP:

HAW:

TNL:

PXY:

API:	100158862(Pole3)

DNX:

AGS:

RMD:

BTAB:

CLEC:

PHU:	Phum_PHUM474950

ZNE:

110828788

FCD:

110848791

PVM:

113812128

ISC:	IscW_ISCW003833

DPTE:

113793634

CSCU:

111614083 111618643

PTEP:

107441768 107454393

CEL:	CELE_T26A5.8(T26A5.8)

CBR:

CBG19681

BMY:	Bm1_04865 Bm1_07285

LOA:	LOAG_09571

NAI:	NECAME_09418 NECAME_15665

TSP:

Tsp_09484

HRO:	HELRODRAFT_75183

LGI:	LOTGIDRAFT_238643

PCAN:

CRG:

MYI:

OBI:

LAK:

SMM:	Smp_198790

SHX:

MS3_07383

OVI:	T265_11110

EGL:

EGR_08888

NVE:	NEMVE_v1g170236

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

AQU:

ATH:	AT2G27470(NF-YB11)

CRB:

111831175

CSAT:

104703556 104752634 104786982

EUS:	EUTSA_v10017865mg

BRP:

103829668

BNA:	106358435 106392073 106399331

BOE:	106332033 106342412

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10029525mg

TCC:

18590310

GRA:

105770909

GHI:	107906690 107959354

GAB:

108453356

DZI:

111285822

EGR:

104421306

GMX:	100306382 100819488

GSJ:	114374405 114380325

PVU:	PHAVU_011G094600g

VRA:

VAR:

VUN:

CCAJ:

MTR:	MTR_4g052950

CAM:

101491905

LJA:	Lj3g3v2994480.1(Lj3g3v2994480.1)

ADU:

AIP:

LANG:

FVE:

RCN:

PPER:

PMUM:

PAVI:

MDM:

PXB:

ZJU:

CSV:

CMO:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

JRE:

QSU:

VVI:

SLY:

SPEN:

SOT:

CANN:

NTA:	107808204 107808429

NSY:

104230566

NTO:

104099883

NAU:	109216479 109236574

INI:

109169235

SIND:

105170020

OEU:	111379511 111383078

HAN:

110908742

LSV:

111917504

CCAV:

112505068

DCR:	108206979 108211703

BVG:

104900308

SOE:

110796074

CQI:	110684239 110684627

NNU:

104588747

PSOM:

113310374 113321970

OSA:

4347894

DOSA:

Os09t0568200-01(Os09g0568200)

OBR:

102717740

BDI:

104584736

ATS:	109774318(LOC109774318)

SBI:

8062546

ZMA:	100282897(CADR16)

SITA:

101760620

EGU:	105033758 105049709

MUS:	103973820 103993568

DCT:

PEQ:

AOF:

ATR:

SMO:	SELMODRAFT_115079 SELMODRAFT_88436

PPP:

112277720

CRE:	CHLREDRAFT_101275

VCN:	VOLCADRAFT_105243

MNG:	MNEG_11435

CVR:	CHLNCDRAFT_14739

OLU:	OSTLU_32755

OTA:	OT_ostta07g03460

MIS:	MICPUN_60106

CME:	CYME_CMR360C

SCE:	YDR121W(DPB4)

AGO:	AGOS_AGR053W

ERC:

Ecym_4295

KLA:	KLLA0_F19426g

KMX:	KLMA_40151(DPB4)

LTH:	KLTH0G13398g

VPO:	Kpol_543p46

ZRO:	ZYRO0D06864g

CGR:	CAGL0B01903g

NCS:	NCAS_0B03750(NCAS0B03750)

NDI:	NDAI_0J01260(NDAI0J01260)

TPF:	TPHA_0A01720(TPHA0A01720)

TBL:	TBLA_0H01430(TBLA0H01430)

TDL:	TDEL_0F04020(TDEL0F04020)

KAF:	KAFR_0B05420(KAFR0B05420)

PPA:	PAS_chr2-1_0100

DHA:	DEHA2G08756g

PIC:	PICST_34779

PGU:	PGUG_02713

SPAA:

SPAPADRAFT_60934

LEL:	LELG_01208

CAL:	CAALFM_C200430CA(DPB4)

CTP:	CTRG_01115

COT:	CORT_0A12650

CDU:	CD36_15400

CTEN:

CANTEDRAFT_101610

YLI:	YALI0A05401g

CLU:	CLUG_00333

CLUS:

A9F13_08g01419

CAUR:

CJI97_001587

PKZ:	C5L36_0B03800

ZTR:	MYCGRDRAFT_29087

SPO:	SPBC3D6.09(dpb4)

TMS:	TREMEDRAFT_24290

HIR:	HETIRDRAFT_328167

CCI:	CC1G_12238

CPUT:

CONPUDRAFT_140608

SLA:	SERLADRAFT_481099

WSE:	WALSEDRAFT_60302

WIC:	J056_000633

MRT:

MRET_3497

PGR:	PGTG_11173

MLR:	MELLADRAFT_92645

DDI:	DDB_G0272222(ybl1)

DPP:	DICPUDRAFT_92261

ACAN:

ACA1_325190

TOT:	TOT_040000568

BMIC:

BMR1_01G00233

FCY:	FRACYDRAFT_164395

TPS:	THAPS_19632

NGD:	NGA_2104400(POLE3)

AAF:	AURANDRAFT_16670

PIF:	PITG_07175

PSOJ:

PHYSODRAFT_407629

SPAR:

SPRG_01401

EHX:	EMIHUDRAFT_237274(POLE3) EMIHUDRAFT_254911

GTT:	GUITHDRAFT_106949

NGR:	NAEGRDRAFT_53490

» show all

Reference

PMID:12124389

Authors

Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A

Title

Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.

Journal

J Biol Chem 277:37422-9 (2002)
DOI:10.1074/jbc.M204476200

Reference

PMID:15388803

Authors

Spiga MG, D'Urso G

Title

Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.

Journal

Nucleic Acids Res 32:4945-53 (2004)
DOI:10.1093/nar/gkh811

Sequence

[spo:SPBC3D6.09]

LinkDB

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