KEGG   ORTHOLOGY: K02554
Entry
K02554                      KO                                     

Name
mhpD
Definition
2-keto-4-pentenoate hydratase [EC:4.2.1.80]
Pathway
ko00360  Phenylalanine metabolism
ko00362  Benzoate degradation
ko00621  Dioxin degradation
ko00622  Xylene degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Module
M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00360 Phenylalanine metabolism
    K02554  mhpD; 2-keto-4-pentenoate hydratase
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
   00622 Xylene degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
   00621 Dioxin degradation
    K02554  mhpD; 2-keto-4-pentenoate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.80  2-oxopent-4-enoate hydratase
     K02554  mhpD; 2-keto-4-pentenoate hydratase
Other DBs
RN: R02601 R04781
COG: COG3971
GO: 0008684
Genes
ECO: b0350(mhpD)
ECJ: JW0341(mhpD)
EBW: BWG_0239(mhpD)
ECOK: ECMDS42_0272(mhpD)
ECE: Z0448(mhpD)
ECS: ECs0405(mhpD)
ECF: ECH74115_0425(mhpD)
ETW: ECSP_0414(mhpD)
ELX: CDCO157_0393(mhpD)
EOI: ECO111_0386(mhpD)
EOJ: ECO26_0386(mhpD)
EOH: ECO103_0332(mhpD)
ECOO: ECRM13514_0496(mhpD)
ECOH: ECRM13516_0330(mhpD)
ESL: O3K_19725(mhpD)
ESO: O3O_05570(mhpD)
ESM: O3M_19710(mhpD)
ECK: EC55989_0357(mhpD)
EOK: G2583_0463(mhpD)
ELR: ECO55CA74_02225(mhpD)
ELH: ETEC_0406
ECW: EcE24377A_0374(mhpD)
ENA: ECNA114_0333(mhpD)
ECOS: EC958_0494
ECOA: APECO78_05270(mhpD)
ECX: EcHS_A0414(mhpD)
ECM: EcSMS35_0381(mhpD)
ECY: ECSE_0375
ECR: ECIAI1_0351(mhpD)
ECQ: ECED1_0378(mhpD)
EUM: ECUMN_0393(mhpD)
ECT: ECIAI39_0328(mhpD)
EOC: CE10_0318(mhpD)
EBR: ECB_00304(mhpD)
EBL: ECD_00304(mhpD)
EBE: B21_00308(mhpD)
EBD: ECBD_3307
ELO: EC042_0387(mhpD)
ESE: ECSF_0321
EKF: KO11_21830(mhpD)
EDJ: ECDH1ME8569_0337(mhpD)
ELW: ECW_m0428(mhpD)
ELL: WFL_02105(mhpD)
ELP: P12B_c0310(mhpD) P12B_c0368(mhpD)
ECOJ: P423_01840
ESZ: FEM44_16325(mhpD)
SSN: SSON_0329(mhpD)
KPN: KPN_02119(mhpD)
KPU: KP1_3214(mhpD)
KPP: A79E_2125
KPT: VK055_0342(mhpD)
KPO: KPN2242_13550(mhpD)
KPR: KPR_2664(mhpD)
KPJ: N559_2171
KPX: PMK1_04483(mhpD)
KPNU: LI86_10785
KPNK: BN49_3224(mhpD)
KVA: Kvar_2156
KPE: KPK_2204(mhpD)
KOX: KOX_22680(mhpD)
KOE: A225_3413
KOY: J415_14965(mhpD)
KLW: DA718_12100(mhpD)
CPOT: FOB25_06045(mhpD)
EBT: EBL_c20010(mhpD)
ROR: RORB6_04290(mhpD)
REE: electrica_02138(mhpD)
KAS: KATP_20200(mhpD)
METY: MRY16398_44950(mhpD)
EBF: D782_1985
LRI: NCTC12151_03196(mhpD)
XCC: XCC0145(mhpD)
XCB: XC_0154
XCA: xcc-b100_0162(mhpD)
XCP: XCR_4394
XCV: XCV0146
XAX: XACM_0146
XAC: XAC0161(mhpD)
XCI: XCAW_00555(mhpD)
XFU: XFF4834R_chr00910(mhpD)
XPH: XppCFBP6546_11120(XppCFBP6546P_11120)
SACZ: AOT14_00290(mhpD)
PSUW: WQ53_07935
LAQ: GLA29479_2995(mhpD)
VEJ: VEJY3_06795(mhpD)
PCQ: PcP3B5_23480(amnF)
PPI: YSA_00251
PPUH: B479_25875(mhpD)
PSYR: N018_13880
PFS: PFLU_3080
PSTT: CH92_09500
PSV: PVLB_26057(mhpD)
PKC: PKB_3259(mhpd1) PKB_3607(mhpd3)
PSOS: POS17_2263
PSET: THL1_492
AVN: Avin_15110(mhpD)
ASJ: AsACE_CH00350(mhpD)
SFR: Sfri_2075
AMAL: I607_15790
AMAE: I876_16090
AMAO: I634_16035
AMAD: I636_15935
AMAI: I635_16575
AMAG: I533_15630
SALH: HMF8227_02738(mhpD)
CJA: CJA_3489
SAGA: M5M_18895
TKM: TK90_1671
HBE: BEI_3014
AXE: P40_10440
KKO: Kkor_0181
KGE: TQ33_0085
MPRI: MP3633_3152(mhpD)
OCE: GU3_08405
CHAE: CH06BL_23620(mhpD)
PSE: NH8B_0739
RSO: RSp0891
RIN: ACS15_4685(amnF)
REH: H16_B0884(mhpD3)
RME: Rmet_5207(mhpD)
BPSE: BDL_4378
BPSM: BBQ_5079
BPSU: BBN_4517
BPSD: BBX_6221
BPK: BBK_6019
BPSH: DR55_4234
BPSA: BBU_4970
BPSO: X996_4292
BUT: X994_6065
BTQ: BTQ_4606
BTJ: BTJ_5589
BTZ: BTL_4056
BTD: BTI_3605
BTV: BTHA_3825
BTHE: BTN_3611
BTHM: BTRA_4310
BTHA: DR62_3645
BTHL: BG87_4063
BOK: DM82_5228
BOC: BG90_5381
BVE: AK36_3500(mhpD) AK36_5145
BCN: Bcen_1441
BCJ: BCAM2124(mhpD)
BCEN: DM39_1993(mhpD) DM39_4968(mhpD) DM39_6931
BCEW: DM40_5002(mhpD) DM40_5268
BCEO: I35_6006(mhpD) I35_7684
BAM: Bamb_5715
BMU: Bmul_5380
BMK: DM80_5595
BMUL: NP80_3432(mhpD) NP80_3870(amnF) NP80_5444
BCED: DM42_7210
BDL: AK34_5279
BUB: BW23_5231
BTEI: WS51_26645
BSTG: WT74_26645
BGU: KS03_4526
BGO: BM43_4845
BUL: BW21_2673(mhpD) BW21_5605
LMIR: NCTC12852_00489(amnF)
CABA: SBC2_18860(mhpD) SBC2_61020(amnF)
BAV: BAV0598(bphE) BAV1871
BHZ: ACR54_00826(mhpD)
TAS: TASI_0989
TAT: KUM_0455
PUT: PT7_2813
ODI: ODI_R1483
AAV: Aave_3417
AJS: Ajs_1712
AAA: Acav_1814
VEI: Veis_3446
DAC: Daci_0212
RTA: Rta_11780
LIH: L63ED372_02447(mhpD)
HYB: Q5W_03225
HAR: HEAR0260
MMS: mma_0313(mhpD)
HSE: Hsero_2670(mhpD) Hsero_3350(mhpD)
CFU: CFU_0048 CFU_0712(mhpD)
AZO: azo1974(mhpD)
AOA: dqs_2129
MES: Meso_1076
AMIH: CO731_05521(mhpD)
PLA: Plav_0344
ARA: Arad_7264
BRS: S23_02150
OCA: OCAR_4168
VGO: GJW-30_1_04157(mhpD_2)
XAU: Xaut_0936
AZC: AZC_1955
BID: Bind_0623
MTUN: MTUNDRAET4_3894(mhpD)
PHL: KKY_3857
BVR: BVIR_1068
PLEO: OHA_1_00190(amnF)
MMED: Mame_00144(mhpD)
CCR: CC_1509
CAK: Caul_1767
CSE: Cseg_1571
PZU: PHZ_c2453(mhpD)
TSV: DSM104635_03438(mhpD)
DSH: Dshi_0880
KVU: EIO_3285
LAQU: R2C4_19315
MALG: MALG_04108
RID: RIdsm_04103(tesE)
HBA: Hbal_2819
GAK: X907_1582
SAL: Sala_3044
SGI: SGRAN_1420(mhpD2)
SPHI: TS85_17615
SPHR: BSY17_3779
BLAS: BSY18_3297
GDI: GDI1198 GDI2732(mhpD)
GDJ: Gdia_1911
GXY: GLX_01150
GXL: H845_1353
KEU: S101446_00488(mhpD)
KSC: CD178_01494(mhpD_1) CD178_02580(mhpD_2) CD178_03513(mhpD)
AZL: AZL_b03340(mhpD) AZL_e00050(mhpD) AZL_e01850
TMO: TMO_1615(mhpD) TMO_b0121(todJ) TMO_b0505(mhpD)
TXI: TH3_13610
MAGQ: MGMAQ_0649
BCA: BCE_2155
BCX: BCA_2153
BCF: bcf_10205
BCER: BCK_24230
BTL: BALH_1842(pheD)
BMYC: DJ92_4636
BMQ: BMQ_3589
BMD: BMD_3574
BMEG: BG04_463
BAG: Bcoa_0268
BACO: OXB_2504
BFD: NCTC4823_00791(mhpD)
BKW: BkAM31D_08365(tesE)
GTN: GTNG_3153(nbaH)
PASA: BAOM_0497(mhpD) BAOM_4648(mhpD)
SEP: SE2356
SEPP: SEB_02355
SHH: ShL2_02366(amnF)
SCA: SCA_0040
SCAP: AYP1020_2148(mhpD)
SARL: SAP2_24020
MCL: MCCL_1828
ASOC: CB4_02450(tesE)
AAC: Aaci_1621
AAD: TC41_1517(mhpD)
BTS: Btus_0967
LRE: Lreu_1904
LRF: LAR_1786
LFE: LAF_0633
LFR: LC40_0435
LFF: LBFF_0654
LKI: LKI_02305
CARC: NY10_794
PTH: PTH_0481
TMR: Tmar_1784
SAY: TPY_0640(mhpD)
MTA: Moth_1777
MTHO: MOTHE_c17910(tesE)
MTHZ: MOTHA_c18740(tesE)
TOC: Toce_0376
STED: SPTER_36980(tesE)
LPIL: LIP_2167
MTU: Rv3536c(hsaE)
MTC: MT3640(mhpD)
MRA: MRA_3575(mhpD)
MTUR: CFBS_3752(mhpD)
MTD: UDA_3536c
MTUB: MT7199_3598(hasE)
MTUE: J114_18910
MTUH: I917_24815
MTUL: TBHG_03476
MTUT: HKBT1_3737(mhpD)
MTUU: HKBT2_3746(mhpD)
MTQ: HKBS1_3749(mhpD)
MBO: BQ2027_MB3566C(hsae)
MBB: BCG_3600c
MBT: JTY_3601
MBX: BCGT_3402
MAF: MAF_35480
MMIC: RN08_3912
MCQ: BN44_110028(mhpD)
MCV: BN43_90034(mhpD)
MCX: BN42_90031(mhpD)
MCZ: BN45_100031(mhpD)
MPA: MAP_0531
MAO: MAP4_3336
MAVI: RC58_16545
MAVU: RE97_16580
MAV: MAV_0625
MID: MIP_00989
MYO: OEM_05420
MIR: OCQ_05500
MLP: MLM_0770
MUL: MUL_4097
MMI: MMAR_5023
MMM: W7S_02620
MHAD: B586_04630
MSHG: MSG_03540 MSG_04521(hsaE)
MXE: MYXE_06130(hsaE)
MSG: MSMEI_5780(mhpD)
MGI: Mflv_1520
MPHL: MPHLCCUG_00565(tesE)
MVQ: MYVA_5131
MTHN: 4412656_04052(mhpD)
MHAS: MHAS_03729(tesE) MHAS_04023(mhpD)
MAUU: NCTC10437_05001(mhpD)
MMAG: MMAD_48000
MMOR: MMOR_12250
MAIC: MAIC_05740
MAB: MAB_0624
MABB: MASS_0594
MCHE: BB28_02990
MSTE: MSTE_00583
MSAL: DSM43276_00542(tesE)
MTER: 4434518_03653(mhpD)
MHIB: MHIB_30710
MKR: MKOR_35780(hsaE)
CDR: CDHC03_1947(mhpD)
CMV: CMUST_15060(mhpD)
CAMG: CAMM_02605
CEE: CENDO_02775(mhpD)
NFR: ERS450000_00751(mhpD_1) ERS450000_01022(mhpD_2) ERS450000_03772(mhpD_4)
NCY: NOCYR_0493(mhpD)
NSR: NS506_01254(bphH)
NAD: NCTC11293_01235(mhpD_1) NCTC11293_04253(mhpD_2) NCTC11293_04413(mhpD_3)
REQ: REQ_42080
RRT: 4535765_04743(cmtF)
RCR: NCTC10994_02786(cmtF)
GOR: KTR9_0810(hsaE)
GRU: GCWB2_04115(tesE1) GCWB2_17420(mhpD)
GOM: D7316_02539(mhpD) D7316_02563(tesE)
TPR: Tpau_3798
SCB: SCAB_15211(bphE) SCAB_2091(mhpD)
SBH: SBI_01533
SDV: BN159_1390(mhpD)
SALS: SLNWT_6913
SALU: DC74_7438
SALL: SAZ_38395
SLAU: SLA_6901
SLX: SLAV_27395(mhpD)
SGE: DWG14_08255(mhpD)
KSK: KSE_23730
ARX: ARZXY2_4005(mhpD)
BLIN: BLSMQ_0563
NDK: I601_0559(mhpD)
SRO: Sros_9115
NML: Namu_4085
AMD: AMED_8623
AMN: RAM_44255
AMM: AMES_8492
AMZ: B737_8493
AOI: AORI_7402(mhpD)
AMYY: YIM_27910(mhpD)
AORI: SD37_03450
PSEA: WY02_18910
PSEE: FRP1_23850
PAUT: Pdca_38550
KAL: KALB_5138
MIL: ML5_3355
AFS: AFR_23755
PFLA: Pflav_027550(mhpD)
AFO: Afer_1182
TER: Tery_1742
RCA: Rcas_2405
CAU: Caur_1357
CAG: Cagg_2039
TRO: trd_1387
TTJ: TTHB239
CAA: Caka_0966
GES: VT84_10640(tesE)
PBOR: BSF38_00915(mhpD)
ACA: ACP_3402
ABAS: ACPOL_1425
AALG: AREALGSMS7_03659(amnF)
STO: STK_01180
 » show all
Reference
  Authors
Diaz E, Ferrandez A, Prieto MA, Garcia JL.
  Title
Biodegradation of aromatic compounds by Escherichia coli.
  Journal
Microbiol Mol Biol Rev 65:523-69, table of contents (2001)
DOI:10.1128/MMBR.65.4.523-569.2001
Reference
PMID:9098055
  Authors
Ferrandez A, Garcia JL, Diaz E.
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J Bacteriol 179:2573-81 (1997)
DOI:10.1128/JB.179.8.2573-2581.1997
  Sequence
[eco:b0350]
LinkDB

KEGG   ORTHOLOGY: K18364
Entry
K18364                      KO                                     

Name
bphH, xylJ, tesE
Definition
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
Pathway
ko00362  Benzoate degradation
ko00621  Dioxin degradation
ko00622  Xylene degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00622 Xylene degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00621 Dioxin degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.80  2-oxopent-4-enoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
    4.2.1.132  2-hydroxyhexa-2,4-dienoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Other DBs
RN: R02601 R05864
GO: 0008684 0034856
Genes
PGE: LG71_12240
PLUM: A4R40_11035
PSD: DSC_09160 DSC_09365
RGL: CS053_01760
RBD: ALSL_1080
VAF: D1115_22450
PRE: PCA10_13820 PCA10_p0350(carD)
PPSE: BN5_3620(nahL)
PCQ: PcP3B5_25700(tesE_1)
PPI: ND086(nahL)
PPUT: L483_14065
PPUN: PP4_27260
PPUU: PputUW4_01660(mhpD)
PKC: PKB_4239(xylJ)
PSET: THL1_1433
AVN: Avin_08670(xylJ) Avin_30610(lapE)
AVL: AvCA_08670(xylJ) AvCA_30610(lapE)
AVD: AvCA6_08670(xylJ) AvCA6_30610(lapE)
SPL: Spea_2118
SHL: Shal_2090
SWD: Swoo_1392
PHA: PSHAa2141(xylJ)
PTN: PTRA_a2594(bphH)
PNG: PNIG_a2788(bphH)
MARJ: MARI_05440(xylJ)
CYQ: Q91_0508
CYY: CPC19_10515(dmpE)
BLEP: AL038_01300(dmpE)
AEH: Mlg_2460
APAC: S7S_06990
NCU: F0U83_03045(dmpE)
NIK: F5I99_10105(dmpE) F5I99_10520(dmpE)
TBN: TBH_C0928
GPB: HDN1F_27090(tesE)
NZO: SAMEA4504057_0450(xylJ)
NCI: NCTC10296_00911(xylJ_1)
RPI: Rpic_4620
RIN: ACS15_4354(dmpE)
REH: H16_B0548(mhpD1) H16_B0597(bphH)
CNC: CNE_2c04940(mhpD) CNE_2c05420(xylJ2) CNE_BB1p11990(xylJ1) CNE_BB1p13280(xylJ2)
RME: Rmet_1321(xylJ)
CTI: RALTA_B0401(mhpD)
COX: E0W60_07775(dmpE) E0W60_08025(dmpE)
BCJ: BCAM1613
BCEN: DM39_3383(dmpE) DM39_4834(dmpE)
BCEO: I35_5473
BCED: DM42_4993(dmpE) DM42_6345(dmpE)
BMEC: WJ16_26790
BXE: Bxe_C1189(bphH)
BXB: DR64_8616(dmpE)
BFN: OI25_4589(dmpE)
PARB: CJU94_37870(dmpE) CJU94_38115(dmpE)
PMEG: FNZ07_21165(dmpE)
CABA: SBC2_49020(tesE)
LIMN: HKT17_03820(dmpE)
KGY: EHF36_01675(dmpE) EHF36_04885(dmpE)
PNA: Pnap_4144
AJS: Ajs_0222
AMON: H9L24_14185(dmpE)
VEI: Veis_2785
VBO: CKY39_28505(dmpE)
CTES: O987_07740
COF: FOZ74_08305(dmpE)
HPSE: HPF_01870(xylJ)
HYN: F9K07_02750(dmpE)
DRG: H9K76_11645(dmpE)
SIMP: C6571_13615(dmpE)
MELA: C6568_07860(dmpE)
METP: C1M51_06460(dmpE) C1M51_15400(dmpE)
JAG: GJA_236(xylJ)
JAJ: EKL02_01815(dmpE)
LCH: Lcho_3343
DEY: HYN24_14130(dmpE) HYN24_14215(dmpE)
AZO: azo1853(lapE) azo2434(nahL)
AZR: CJ010_12250(dmpE) CJ010_15220(dmpE)
AZQ: G3580_00535(dmpE) G3580_08270(dmpE)
THK: CCZ27_10770(dmpE) CCZ27_16275(dmpE)
AAQI: AAQM_0980(dmpE)
ACIB: ACBT_0261(dmpE)
ACLO: ACLO_a0141(dmpE)
AANA: AANAER_1258(dmpE)
ALK: ALEK_0381(dmpE)
ADZ: ADFLV_2553(dmpE)
AFC: AFAEC_1846(dmpE)
ARC: ABLL_2444
NAR: Saro_3689
SGI: SGRAN_1581(mhpD)
SPHM: G432_01985
SSAN: NX02_12710
SPKC: KC8_03560
SJP: SJA_C1-11870(mhpD)
SPHB: EP837_03394(bphH)
SINB: SIDU_08330
SFLA: SPHFLASMR4Y_02368(tesE)
HTL: HPTL_0050
CWO: Cwoe_3997
AG: BAC67694(tesE)
 » show all
Reference
  Authors
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T
  Title
Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.
  Journal
Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005
  Sequence
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