KEGG   ORTHOLOGY: K02649
Entry
K02649                      KO                                     

Name
PIK3R1_2_3
Definition
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map01524  Platinum drug resistance
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04210  Apoptosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04218  Cellular senescence
map04360  Axon guidance
map04370  VEGF signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04666  Fc gamma R-mediated phagocytosis
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map04910  Insulin signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04926  Relaxin signaling pathway
map04929  GnRH secretion
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04973  Carbohydrate digestion and absorption
map05010  Alzheimer disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05135  Yersinia infection
map05142  Chagas disease
map05146  Amoebiasis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H01370  SHORT syndrome
H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04014 Ras signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04015 Rap1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04370 VEGF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04630 JAK-STAT signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04668 TNF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04066 HIF-1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04068 FoxO signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04070 Phosphatidylinositol signaling system
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04072 Phospholipase D signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04071 Sphingolipid signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04024 cAMP signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04151 PI3K-Akt signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04152 AMPK signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04150 mTOR signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09143 Cell growth and death
   04210 Apoptosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04218 Cellular senescence
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04550 Signaling pathways regulating pluripotency of stem cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04613 Neutrophil extracellular trap formation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04620 Toll-like receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04625 C-type lectin receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04650 Natural killer cell mediated cytotoxicity
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04660 T cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04662 B cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04664 Fc epsilon RI signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04666 Fc gamma R-mediated phagocytosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04670 Leukocyte transendothelial migration
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04062 Chemokine signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09152 Endocrine system
   04910 Insulin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04923 Regulation of lipolysis in adipocytes
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04929 GnRH secretion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04915 Estrogen signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04914 Progesterone-mediated oocyte maturation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04917 Prolactin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04926 Relaxin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04935 Growth hormone synthesis, secretion and action
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04919 Thyroid hormone signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09156 Nervous system
   04725 Cholinergic synapse
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04722 Neurotrophin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09158 Development and regeneration
   04360 Axon guidance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04380 Osteoclast differentiation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09149 Aging
   04211 Longevity regulating pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04213 Longevity regulating pathway - multiple species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05206 MicroRNAs in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05205 Proteoglycans in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05207 Chemical carcinogenesis - receptor activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05208 Chemical carcinogenesis - reactive oxygen species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05203 Viral carcinogenesis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05230 Central carbon metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05231 Choline metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05212 Pancreatic cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05225 Hepatocellular carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05226 Gastric cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05214 Glioma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05221 Acute myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05220 Chronic myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05218 Melanoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05211 Renal cell carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05215 Prostate cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05213 Endometrial cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05224 Breast cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05222 Small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05223 Non-small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05170 Human immunodeficiency virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05161 Hepatitis B
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05160 Hepatitis C
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05171 Coronavirus disease - COVID-19
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05164 Influenza A
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05162 Measles
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05168 Herpes simplex virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05163 Human cytomegalovirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05169 Epstein-Barr virus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05165 Human papillomavirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05135 Yersinia infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05100 Bacterial invasion of epithelial cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05142 Chagas disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05017 Spinocerebellar ataxia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05020 Prion disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05418 Fluid shear stress and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05415 Diabetic cardiomyopathy
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04932 Non-alcoholic fatty liver disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04931 Insulin resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01524 Platinum drug resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01522 Endocrine resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Other DBs
RN: R03362 R04545 R05795
Genes
HSA: 5295(PIK3R1) 5296(PIK3R2) 8503(PIK3R3)
PTR: 455855(PIK3R2) 456565(PIK3R3) 461836(PIK3R1)
PPS: 100969981(PIK3R2) 100986080(PIK3R3) 100994315(PIK3R1)
GGO: 101129336(PIK3R3) 101130978(PIK3R1) 101135298(PIK3R2)
PON: 100173589(PIK3R1) 100174298(PIK3R3) 100437617(PIK3R2)
NLE: 100591270(PIK3R3) 100599301(PIK3R2) 100605788(PIK3R1)
MCC: 698996(PIK3R1) 707310(PIK3R3) 719367(PIK3R2)
MCF: 101866246(PIK3R1) 102124804(PIK3R2) 102137291(PIK3R3)
CSAB: 103222594(PIK3R1) 103224900(PIK3R3) 103234391(PIK3R2)
CATY: 105571321(PIK3R2) 105594576(PIK3R3) 105599262(PIK3R1)
PANU: 100510873(PIK3R1) 101002971(PIK3R3) 101009981(PIK3R2)
RRO: 104662124(PIK3R3) 104675620(PIK3R1) 104680672(PIK3R2)
RBB: 108534276(PIK3R2) 108535636(PIK3R3) 108541175(PIK3R1)
TFN: 117065206(PIK3R1) 117075022(PIK3R2) 117092662(PIK3R3)
PTEH: 111539891(PIK3R1) 111548774(PIK3R3) 111554247(PIK3R2)
CJC: 100392639(PIK3R1) 100406689(PIK3R2) 100414659(PIK3R3)
SBQ: 101032496(PIK3R1) 101033359(PIK3R2) 101050592(PIK3R3)
MMUR: 105855026(PIK3R2) 105877483(PIK3R3) 105881219(PIK3R1)
MMU: 18708(Pik3r1) 18709(Pik3r2) 18710(Pik3r3)
MCAL: 110292624 110299855(Pik3r2) 110308009(Pik3r1)
MPAH: 110322865(Pik3r3) 110328811(Pik3r1) 110336420(Pik3r2)
RNO: 25513(Pik3r1) 29741(Pik3r2) 60664(Pik3r3)
MCOC: 116069491(Pik3r2) 116083721(Pik3r1) 116096465(Pik3r3)
MUN: 110549145(Pik3r2) 110553683(Pik3r1) 110563512(Pik3r3)
CGE: 100750761(Pik3r1) 100771181(Pik3r2) 100774067
PLEU: 114688966(Pik3r2) 114703850(Pik3r1) 114706924(Pik3r3)
NGI: 103726879(Pik3r2) 103730305(Pik3r3) 103738715(Pik3r1)
HGL: 101703691(Pik3r1) 101717096(Pik3r3) 101718815(Pik3r2)
CCAN: 109682432(Pik3r3) 109682554 109694666(Pik3r1)
OCU: 100345250(PIK3R3) 100357841(PIK3R1)
TUP: 102469401(PIK3R2) 102484444(PIK3R3) 102484500(PIK3R1)
CFA: 100856339 487235(PIK3R1) 609956(PIK3R2)
VVP: 112913170(PIK3R2) 112914774 112935820(PIK3R1)
VLG: 121481416 121494738(PIK3R2) 121496480(PIK3R1)
AML: 100467916(PIK3R3) 100475291(PIK3R2) 100483828(PIK3R1)
UMR: 103663617(PIK3R1) 103670766(PIK3R3) 103675162(PIK3R2)
UAH: 113254730(PIK3R3) 113255266(PIK3R1) 113256705(PIK3R2)
ORO: 101370100(PIK3R1) 101371800(PIK3R2) 101374787(PIK3R3)
MPUF: 101680399(PIK3R2) 101683594 101683710(PIK3R1)
EJU: 114224308 114224631(PIK3R1) 114226659(PIK3R2)
MLX: 118006042(PIK3R2) 118016863(PIK3R1) 118019468(PIK3R3)
FCA: 100271864(PIK3R1) 101093286(PIK3R3) 101093586(PIK3R2)
PTG: 102949853(PIK3R3) 102952993(PIK3R1) 102967709(PIK3R2)
PPAD: 109247606(PIK3R2) 109266953(PIK3R3) 109275060(PIK3R1)
AJU: 106969150(PIK3R2) 106973297(PIK3R3) 106976917(PIK3R1)
HHV: 120219997(PIK3R1) 120239233(PIK3R2) 120247089
BTA: 282307(PIK3R1) 282308(PIK3R2) 286865(PIK3R3)
BOM: 102266922(PIK3R1) 102280296(PIK3R3) 102286868(PIK3R2)
BIU: 109556345 109561418(PIK3R2) 109574805(PIK3R1)
BBUB: 102395384 102404517(PIK3R2) 102415109(PIK3R1)
CHX: 102170135(PIK3R2) 102179343(PIK3R3) 102188710(PIK3R1)
OAS: 101111546(PIK3R2) 101121455(PIK3R1) 101123247(PIK3R3)
ODA: 120856226 120864210(PIK3R2) 120879604(PIK3R1)
SSC: 100511937 100623707(PIK3R1) 100739510(PIK3R2)
CFR: 102505690 102513205(PIK3R2) 102520923(PIK3R1)
CDK: 105084758(PIK3R1) 105092913 105101867(PIK3R2)
BACU: 103007464(PIK3R1) 103008077(PIK3R3) 103009307(PIK3R2)
LVE: 103070370(PIK3R1) 103078725(PIK3R3) 103083960(PIK3R2)
OOR: 101277568(PIK3R3) 101281352(PIK3R2) 101285437(PIK3R1)
DLE: 111166652(PIK3R2) 111175760 111185984(PIK3R1)
PCAD: 102975555(PIK3R3) 102991192(PIK3R1) 102991779(PIK3R2)
ECB: 100050227(PIK3R1) 100052122 100146348(PIK3R2)
EPZ: 103548220(PIK3R1) 103551868(PIK3R3) 103561550(PIK3R2)
EAI: 106822593(PIK3R3) 106824993(PIK3R2) 106840141(PIK3R1)
MYB: 102242302(PIK3R1) 102253405(PIK3R2) 102258430(PIK3R3)
MYD: 102753036(PIK3R1) 102760468(PIK3R3) 102763670(PIK3R2)
MMYO: 118656203(PIK3R1) 118657573(PIK3R2) 118675217
MNA: 107526728(PIK3R3) 107529317(PIK3R1) 107535325(PIK3R2)
HAI: 109373811(PIK3R3) 109382484(PIK3R2) 109395865(PIK3R1)
DRO: 112305224(PIK3R2) 112314466 112321016(PIK3R1)
SHON: 118975178(PIK3R2) 118982454(PIK3R3) 118998595(PIK3R1)
AJM: 119046830(PIK3R2) 119052227 119053288(PIK3R1)
MMF: 118616460(PIK3R2) 118626685 118642883(PIK3R1)
PALE: 102879163(PIK3R1) 102879453(PIK3R2) 102891637
RAY: 107498704(PIK3R1) 107517899(PIK3R3) 107521668(PIK3R2)
MJV: 108383561(PIK3R2) 108390475(PIK3R1) 108395975(PIK3R3)
TOD: 119237093(PIK3R3) 119241117(PIK3R2) 119260810(PIK3R1)
LAV: 100653731(PIK3R1) 100665045(PIK3R2) 100675496(PIK3R3)
MDO: 100019317(PIK3R1) 100032726(PIK3R2) 100616957(PIK3R3)
SHR: 100924976(PIK3R1) 100926892(PIK3R2) 100935230(PIK3R3)
PCW: 110209293(PIK3R3) 110216530(PIK3R1) 110223395(PIK3R2)
OAA: 100080187(PIK3R2) 100082075(PIK3R3) 103167126(PIK3R1)
GGA: 427171(PIK3R1) 429096(PIK3R3) 771142(PIK3R2)
PCOC: 116234220 116235709(PIK3R2) 116239922(PIK3R1)
CJO: 107305909(PIK3R1) 107317608 107325533(PIK3R2)
NMEL: 110388756(PIK3R2) 110389564(PIK3R1) 110402756(PIK3R3)
APLA: 101795759 101799717(PIK3R1) 101803461(PIK3R2)
ACYG: 106033049(PIK3R3) 106042106(PIK3R1) 106045000(PIK3R2)
TGU: 100221185 100223949(PIK3R1) 100226234(PIK3R2)
LSR: 110469696 110472594(PIK3R1) 110478008(PIK3R2)
SCAN: 103814989 103821918(PIK3R2) 103823133(PIK3R1) 115483908
PMOA: 120498082(PIK3R2) 120502343(PIK3R1) 120503174
GFR: 102032353(PIK3R1) 102035891(PIK3R2) 102039817(PIK3R3)
FAB: 101811808(PIK3R2) 101812251(PIK3R3) 101820843(PIK3R1)
PHI: 102106897(PIK3R2) 102112482(PIK3R3) 102114750(PIK3R1)
PMAJ: 107208273(PIK3R3) 107215603(PIK3R2) 107216262(PIK3R1)
CCAE: 111933104(PIK3R3) 111940405(PIK3R2) 111941370(PIK3R1)
CCW: 104686712(PIK3R1) 104695234 104696977(PIK3R2)
FPG: 101913266(PIK3R3) 101915242(PIK3R2) 101924523(PIK3R1)
FCH: 102056135(PIK3R1) 102057083(PIK3R2) 102059517
CLV: 102084272(PIK3R3) 102084904(PIK3R2) 102092838(PIK3R1)
EGZ: 104124880(PIK3R1) 104126253(PIK3R3) 104135641(PIK3R2)
NNI: 104015409(PIK3R3) 104018715(PIK3R2)
ACUN: 113483193 113489298(PIK3R2) 113489600(PIK3R1)
PADL: 103919124(PIK3R3) 103919717(PIK3R1) 103926435(PIK3R2)
AAM: 106485939(PIK3R3) 106495610(PIK3R2) 106499441(PIK3R1)
ASN: 102377899(PIK3R2) 102380057 102382060(PIK3R1)
AMJ: 102567863(PIK3R2) 102570922(PIK3R1) 106737141(PIK3R3)
CPOO: 109307425(PIK3R3) 109307980(PIK3R1) 109312353(PIK3R2)
GGN: 109286709(PIK3R3) 109294997(PIK3R2) 109297752(PIK3R1)
PSS: 102449585(PIK3R1) 102457516
CMY: 102933845(PIK3R2) 102941819 102945631(PIK3R1)
CPIC: 101945673(PIK3R2) 101947423(PIK3R3) 101953817(PIK3R1)
TST: 117868848(PIK3R2) 117879552(PIK3R1) 117881251
CABI: 116826231(PIK3R2) 116839230 116839322(PIK3R1)
ACS: 100554618(pik3r3) 100555182(pik3r2) 100556883(pik3r1)
PVT: 110072561(PIK3R2) 110073778(PIK3R3) 110073951(PIK3R1)
PBI: 103055280(PIK3R2) 103065132 103065975(PIK3R1)
PMUR: 107282273(PIK3R2) 107283596 107286152(PIK3R1)
TSR: 106538977(PIK3R1) 106543200(PIK3R3) 106552169
PGUT: 117664160 117677371(PIK3R2) 117679253(PIK3R1)
PMUA: 114588236(PIK3R2) 114599062 114606162(PIK3R1)
ZVI: 118077038(PIK3R1) 118085906(PIK3R2) 118088990
GJA: 107108905(PIK3R1) 107119473(PIK3R3) 107121678(PIK3R2)
XLA: 108706884(pik3r2.S) 108713027(pik3r2.L) 399202(pik3r1.S) 443964(pik3r1.L) 446786(pik3r3.S) 447594(pik3r3.L)
XTR: 100486835(pik3r1) 100497001(pik3r2) 549983(pik3r3)
NPR: 108789013(PIK3R2) 108797628(PIK3R1) 108802963
DRE: 100000252(pik3r3b) 404211(pik3r2) 557176(pik3r1)
IPU: 108260231(pik3r1) 108272037(pik3r3)
PHYP: 113531632(pik3r1) 113538265
AMEX: 103029972(pik3r3) 103035767 103046618(pik3r1) 111190801
ELY: 117252529 117254143 117254148(pik3r3b) 117269552(pik3r1) 117271502 117271508(pik3r2)
PLEP: 121938061 121939825 121951302 121951926(pik3r2) 121959511(pik3r1) 121962939(pik3r3b)
SLUC: 116037246(pik3r2) 116045807 116053059 116056635 116056995(pik3r3b) 116062801(pik3r1)
ECRA: 117944918 117950300 117950796(pik3r3b) 117953620(pik3r2) 117954000 117959815(pik3r1)
GAT: 120815842(pik3r2) 120816124 120823475 120823622(pik3r3b) 120830750 120831616(pik3r1)
MSAM: 119891547 119900224(pik3r3b) 119900503 119902234(pik3r2) 119902368 119914041(pik3r1)
CUD: 121509697 121512025(pik3r3b) 121512376 121519790 121519794(pik3r2) 121524754(pik3r1)
PRET: 103463201(pik3r3) 103463319 103470780 103473324(pik3r1) 103478998 103479173(pik3r2)
KMR: 108234365 108238336 108244850(pik3r2) 108245882 108247561(pik3r3b) 108250884(pik3r1)
XGL: 120790713 120791111(pik3r3b) 120799080(pik3r2) 120799460 120805057 120806252(pik3r1)
MALB: 109957384 109965201(pik3r3) 109966856 109969301(pik3r2) 109969763(pik3r1) 109970672
PKI: 111834821(pik3r3) 111835615(pik3r1) 111847640 111856594 111860386(pik3r2)
LOC: 102687995(pik3r2) 102693436(pik3r3) 102696821(pik3r1)
LCM: 102348007(PIK3R3) 102353218(PIK3R1)
CMK: 103177781(pik3r1) 103182064(pik3r2) 103182762(pik3r3)
BFO: 118432571
CIN: 100184893
SCLV: 120335427
SPU: 588766
APLC: 110977729
SKO: 100372481
DME: Dmel_CG2699(Pi3K21B)
DER: 6543312
DSE: 6621105
DSI: Dsimw501_GD23016(Dsim_GD23016)
DSR: 110187562
DPE: 6593764
DMN: 108163765
DWI: 6651829
DAZ: 108609449
DNV: 108650034
DHE: 111602464
DVI: 6628686
MDE: 101896300
LCQ: 111686430
ACOZ: 120953852
AARA: 120897556
AAG: 5578257
AALB: 109409609
CPII: 120413155
AME: 408577
ACER: 107993600
BIM: 100743083
BTER: 100643962
CCAL: 108629871
OBB: 114871807
MGEN: 117229216
NMEA: 116432267
SOC: 105195470
MPHA: 105831984
AEC: 105151922
ACEP: 105620878
PBAR: 105430848
VEM: 105567561
HST: 105192434
DQU: 106748226
CFO: 105255336
LHU: 105667777
PGC: 109854747
OBO: 105284404
PCF: 106792271
NVI: 100122747
CSOL: 105361583
MDL: 103580680
TCA: 100141888
DPA: 109540864
ATD: 109595073
AGB: 108916999
NVL: 108559788
PPYR: 116166071
OTU: 111425557
BMOR: 100158253(Pi3k60)
BMAN: 114245941
MSEX: 115453059
BANY: 112044673
PMAC: 106714800
PPOT: 106106684
PRAP: 110992252
ZCE: 119834537
HAW: 110370679
TNL: 113497575
PXY: 105388447
AGS: 114129704
RMD: 113553291
BTAB: 109032766
CLEC: 106664096
NLU: 111047698
FCD: 110845224
PVM: 113810630
HAME: 121864257
EAF: 111697024
DSV: 119433196
RSAN: 119404584
RMP: 119181020
VDE: 111248584
VJA: 111273172
DPTE: 113798240
CEL: CELE_Y110A7A.10(aap-1)
CBR: CBG10815(Cbr-aap-1)
BMY: BM_BM7280(Bma-aap-1)
TSP: Tsp_02388
BGT: 106064965
CRG: 105321629
OBI: 106879157
EGL: EGR_06563
NVE: 5520340
EPA: 110239539
ATEN: 116307342
ADF: 107335159
AMIL: 114952874
PDAM: 113679985
SPIS: 111326832
DGT: 114527321
HMG: 100197475
 » show all
Reference
PMID:1849461
  Authors
Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schlessinger J
  Title
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.
  Journal
Cell 65:83-90 (1991)
DOI:10.1016/0092-8674(91)90410-Z
  Sequence
[hsa:5295]
Reference
PMID:9582025
  Authors
Janssen JW, Schleithoff L, Bartram CR, Schulz AS
  Title
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme.
  Journal
Oncogene 16:1767-72 (1998)
DOI:10.1038/sj.onc.1201695
  Sequence
[hsa:5296]
Reference
PMID:9524259
  Authors
Dey BR, Furlanetto RW, Nissley SP
  Title
Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.
  Journal
Gene 209:175-83 (1998)
DOI:10.1016/S0378-1119(98)00045-6
  Sequence
[hsa:8503]
LinkDB

KEGG   ORTHOLOGY: K00922
Entry
K00922                      KO                                     

Name
PIK3CA_B_D
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Pathway
map00562  Inositol phosphate metabolism
map01100  Metabolic pathways
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map01524  Platinum drug resistance
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04210  Apoptosis
map04211  Longevity regulating pathway
map04212  Longevity regulating pathway - worm
map04213  Longevity regulating pathway - multiple species
map04218  Cellular senescence
map04360  Axon guidance
map04361  Axon regeneration
map04370  VEGF signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04666  Fc gamma R-mediated phagocytosis
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map04910  Insulin signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04926  Relaxin signaling pathway
map04929  GnRH secretion
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04973  Carbohydrate digestion and absorption
map05010  Alzheimer disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05132  Salmonella infection
map05135  Yersinia infection
map05142  Chagas disease
map05146  Amoebiasis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00027  Ovarian cancer
H00031  Breast cancer
H00048  Hepatocellular carcinoma
H01102  Pituitary adenomas
H01222  Cowden syndrome
H01387  Activated PI3K-delta syndrome
H01431  Cushing syndrome
H01912  Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi
H01985  Desmoplastic small round cell tumor
H02153  Megalencephaly-capillary malformation syndrome
H02297  CLAPO syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04014 Ras signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04015 Rap1 signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04370 VEGF signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04630 JAK-STAT signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04668 TNF signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04066 HIF-1 signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04068 FoxO signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04070 Phosphatidylinositol signaling system
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04072 Phospholipase D signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04071 Sphingolipid signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04024 cAMP signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04151 PI3K-Akt signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04152 AMPK signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04150 mTOR signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09143 Cell growth and death
   04210 Apoptosis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04218 Cellular senescence
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04550 Signaling pathways regulating pluripotency of stem cells
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04613 Neutrophil extracellular trap formation
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04620 Toll-like receptor signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04625 C-type lectin receptor signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04650 Natural killer cell mediated cytotoxicity
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04660 T cell receptor signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04662 B cell receptor signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04664 Fc epsilon RI signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04666 Fc gamma R-mediated phagocytosis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04670 Leukocyte transendothelial migration
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04062 Chemokine signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09152 Endocrine system
   04910 Insulin signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04923 Regulation of lipolysis in adipocytes
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04929 GnRH secretion
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04915 Estrogen signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04914 Progesterone-mediated oocyte maturation
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04917 Prolactin signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04926 Relaxin signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04935 Growth hormone synthesis, secretion and action
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04919 Thyroid hormone signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09156 Nervous system
   04725 Cholinergic synapse
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04722 Neurotrophin signaling pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09158 Development and regeneration
   04360 Axon guidance
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04361 Axon regeneration
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04380 Osteoclast differentiation
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09149 Aging
   04211 Longevity regulating pathway
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04212 Longevity regulating pathway - worm
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04213 Longevity regulating pathway - multiple species
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05206 MicroRNAs in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05205 Proteoglycans in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05207 Chemical carcinogenesis - receptor activation
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05208 Chemical carcinogenesis - reactive oxygen species
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05203 Viral carcinogenesis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05230 Central carbon metabolism in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05231 Choline metabolism in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09162 Cancer: specific types
   05210 Colorectal cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05212 Pancreatic cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05225 Hepatocellular carcinoma
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05226 Gastric cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05214 Glioma
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05221 Acute myeloid leukemia
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05220 Chronic myeloid leukemia
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05218 Melanoma
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05211 Renal cell carcinoma
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05215 Prostate cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05213 Endometrial cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05224 Breast cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05222 Small cell lung cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05223 Non-small cell lung cancer
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05170 Human immunodeficiency virus 1 infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05161 Hepatitis B
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05160 Hepatitis C
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05171 Coronavirus disease - COVID-19
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05164 Influenza A
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05162 Measles
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05168 Herpes simplex virus 1 infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05163 Human cytomegalovirus infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05169 Epstein-Barr virus infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05165 Human papillomavirus infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05131 Shigellosis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05135 Yersinia infection
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05100 Bacterial invasion of epithelial cells
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05142 Chagas disease
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05017 Spinocerebellar ataxia
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05020 Prion disease
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05418 Fluid shear stress and atherosclerosis
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   05415 Diabetic cardiomyopathy
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04932 Non-alcoholic fatty liver disease
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04931 Insulin resistance
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   04933 AGE-RAGE signaling pathway in diabetic complications
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   01524 Platinum drug resistance
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
   01522 Endocrine resistance
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
Other DBs
RN: R04545
GO: 0046934
Genes
HSA: 5290(PIK3CA) 5291(PIK3CB) 5293(PIK3CD)
PTR: 457922(PIK3CD) 460858(PIK3CA) 471079(PIK3CB)
PPS: 100989732(PIK3CD) 100990108(PIK3CB) 100990828(PIK3CA)
GGO: 101143811(PIK3CA) 101146434(PIK3CD) 101152123(PIK3CB)
PON: 100432846(PIK3CB) 100453779(PIK3CA) 103889133(PIK3CD)
NLE: 100580872(PIK3CD) 100584384(PIK3CB) 100588218(PIK3CA)
MCC: 709959(PIK3CA) 710552(PIK3CD) 716098(PIK3CB)
MCF: 102122725(PIK3CA) 102142026(PIK3CB) 102143464(PIK3CD)
CSAB: 103221212(PIK3CA) 103225637(PIK3CD) 103241599(PIK3CB)
CATY: 105580892(PIK3CD) 105586383(PIK3CB) 105597716(PIK3CA)
PANU: 101002278(PIK3CD) 101004976(PIK3CA) 101008699(PIK3CB)
RRO: 104663050(PIK3CD) 104665061(PIK3CB) 104670605(PIK3CA)
RBB: 108532960(PIK3CA) 108539355(PIK3CD) 108544591(PIK3CB)
TFN: 117083761(PIK3CA) 117084122(PIK3CB) 117093348(PIK3CD)
PTEH: 111521403(PIK3CA) 111523340(PIK3CB) 111544647(PIK3CD)
CJC: 100391655(PIK3CB) 100398849(PIK3CD) 100403494(PIK3CA)
SBQ: 101027982(PIK3CB) 101029768(PIK3CA) 101052779(PIK3CD)
MMUR: 105855821(PIK3CA) 105862660(PIK3CB) 105886063(PIK3CD)
MMU: 18706(Pik3ca) 18707(Pik3cd) 74769(Pik3cb)
MCAL: 110290798(Pik3ca) 110292183(Pik3cd) 110301355(Pik3cb)
MPAH: 110319750(Pik3ca) 110323448(Pik3cd) 110327251(Pik3cb)
RNO: 170911(Pik3ca) 366508(Pik3cd) 85243(Pik3cb)
MCOC: 116073929(Pik3cb) 116095058(Pik3ca) 116097037(Pik3cd)
MUN: 110548394(Pik3cb) 110556252(Pik3ca) 110565112(Pik3cd)
CGE: 100689251(Pik3ca) 100689252(Pik3cb) 100769225(Pik3cd)
PLEU: 114684032(Pik3cd) 114693559(Pik3cb) 114695335(Pik3ca)
NGI: 103733121(Pik3cd) 103738596(Pik3ca) 103742946(Pik3cb)
HGL: 101711934(Pik3ca) 101712941(Pik3cd) 101715249(Pik3cb)
CCAN: 109681900(Pik3cd) 109689664(Pik3ca)
OCU: 100337822(PIK3CA) 100345181(PIK3CB) 100348663(PIK3CD)
TUP: 102483329(PIK3CA) 102500530(PIK3CD) 102502163(PIK3CB) 106736453
CFA: 477085(PIK3CB) 488084(PIK3CA) 489644(PIK3CD)
VVP: 112924665(PIK3CD) 112926217(PIK3CA) 112934961(PIK3CB)
VLG: 121477352(PIK3CA) 121478805(PIK3CB) 121499678(PIK3CD)
AML: 100463775(PIK3CB) 100479294(PIK3CA) 100479580(PIK3CD)
UMR: 103666874(PIK3CD) 103676125(PIK3CA) 103678592(PIK3CB)
UAH: 113253989(PIK3CB) 113254799(PIK3CA) 113270537(PIK3CD)
ORO: 101370689(PIK3CA) 101385241(PIK3CB) 101385267(PIK3CD)
MPUF: 101676567(PIK3CD) 101681650(PIK3CB) 101684443(PIK3CA)
EJU: 114205617(PIK3CB) 114206954(PIK3CA) 114213130(PIK3CD)
MLX: 118004424(PIK3CB) 118006556(PIK3CA) 118020028(PIK3CD)
FCA: 101091892(PIK3CB) 101094274(PIK3CD) 101097413(PIK3CA)
PTG: 102953082(PIK3CD) 102965070(PIK3CA) 102972487(PIK3CB)
PPAD: 109259912(PIK3CB) 109274075(PIK3CD) 109275159(PIK3CA)
AJU: 106973880(PIK3CA) 106984265(PIK3CB) 106984896(PIK3CD)
HHV: 120220979(PIK3CB) 120233608(PIK3CD) 120246696(PIK3CA)
BTA: 282306(PIK3CA) 504531(PIK3CD) 517948(PIK3CB)
BOM: 102274461(PIK3CD) 102274553(PIK3CA) 102277548(PIK3CB)
BIU: 109557823(PIK3CA) 109559805(PIK3CB) 109570415(PIK3CD)
BBUB: 102400519(PIK3CA) 102404165(PIK3CB) 102404610(PIK3CD)
CHX: 102168391(PIK3CA) 102177551(PIK3CD) 102185042(PIK3CB)
OAS: 101109759(PIK3CB) 101110015(PIK3CA) 101117348(PIK3CD)
ODA: 120857849(PIK3CB) 120871400(PIK3CA) 120880186(PIK3CD)
SSC: 100518131(PIK3CD) 100621789(PIK3CA) 100622559(PIK3CB)
CFR: 102518643(PIK3CD) 102519994(PIK3CB) 102523502(PIK3CA)
CDK: 105085928(PIK3CA) 105086305(PIK3CB) 105107003(PIK3CD)
BACU: 103012691(PIK3CA) 103012931(PIK3CB) 103014043(PIK3CD)
LVE: 103085303(PIK3CA) 103088756(PIK3CB) 103089257(PIK3CD)
OOR: 101278075(PIK3CA) 101278974(PIK3CD) 101283011(PIK3CB)
DLE: 111173839(PIK3CA) 111179235(PIK3CB) 111187262(PIK3CD)
PCAD: 102977108(PIK3CB) 102978952(PIK3CD) 102986098(PIK3CA)
ECB: 100051623(PIK3CD) 100051753(PIK3CB) 100058141(PIK3CA)
EPZ: 103549076(PIK3CD) 103552150(PIK3CA) 103554655
EAI: 106829313(PIK3CA) 106836695(PIK3CD) 106838100(PIK3CB)
MYB: 102239669(PIK3CA) 102252921(PIK3CD) 102260487(PIK3CB)
MYD: 102758951(PIK3CA) 102764343(PIK3CB) 102766356(PIK3CD)
MMYO: 118668125(PIK3CB) 118675045(PIK3CA) 118677590(PIK3CD)
MNA: 107532628(PIK3CB) 107538463(PIK3CD) 107541106(PIK3CA)
HAI: 109372681(PIK3CA) 109381238(PIK3CD) 109394108(PIK3CB)
DRO: 112299448(PIK3CD) 112307667(PIK3CA) 112310002(PIK3CB)
SHON: 118986375(PIK3CD) 118995662 118997522(PIK3CB)
AJM: 119043036(PIK3CA) 119044861(PIK3CB) 119064089(PIK3CD)
MMF: 118617106(PIK3CA) 118626944(PIK3CD) 118632927(PIK3CB)
PALE: 102880320(PIK3CB) 102889227(PIK3CA) 102889576(PIK3CD)
RAY: 107513958(PIK3CB) 107517828(PIK3CA) 107520152(PIK3CD)
MJV: 108390365(PIK3CD) 108400388(PIK3CB) 108406544(PIK3CA)
TOD: 119236721(PIK3CD) 119257304(PIK3CA) 119257726(PIK3CB)
LAV: 100657948(PIK3CA) 100658340(PIK3CB) 100666266(PIK3CD)
MDO: 100010412(PIK3CA) 100017332(PIK3CB) 100024769(PIK3CD)
SHR: 100929811(PIK3CB) 100932099(PIK3CA) 105749979(PIK3CD)
PCW: 110199476(PIK3CD) 110204454(PIK3CA) 110208219(PIK3CB)
OAA: 100073788(PIK3CA) 100074273(PIK3CD) 100086270(PIK3CB)
GGA: 419444(PIK3CD) 424826(PIK3CB) 424971(PIK3CA)
PCOC: 116230949(PIK3CB) 116242673(PIK3CD) 116243400(PIK3CA)
MGP: 100543492(PIK3CD) 100546867(PIK3CA)
CJO: 107317945(PIK3CB) 107318114(PIK3CA) 107323497(PIK3CD)
NMEL: 110397252(PIK3CB) 110398160(PIK3CA) 110408755(PIK3CD)
APLA: 101796183(PIK3CA) 101800900(PIK3CB) 101802796(PIK3CD)
ACYG: 106032026(PIK3CA) 106040311(PIK3CB) 106044285(PIK3CD)
TGU: 100219602(PIK3CB) 100224188(PIK3CD) 100229768(PIK3CA)
LSR: 110474406(PIK3CD) 110478031(PIK3CA) 110484828(PIK3CB)
SCAN: 103815304(PIK3CA) 103820781(PIK3CD) 103824201(PIK3CB)
PMOA: 120504196(PIK3CA) 120511114(PIK3CD) 120511220(PIK3CB)
GFR: 102040845(PIK3CB) 102040853(PIK3CD) 102042284(PIK3CA)
FAB: 101811931(PIK3CD) 101814811(PIK3CA) 101821801(PIK3CB)
PHI: 102099156(PIK3CA) 102103635(PIK3CD) 102106643(PIK3CB)
PMAJ: 107208827(PIK3CA) 107208852(PIK3CB) 107213667(PIK3CD)
CCAE: 111933356(PIK3CA) 111933753(PIK3CB) 111938683(PIK3CD)
CCW: 104688020(PIK3CA) 104693039(PIK3CB) 104693336(PIK3CD)
ETL: 114056876(PIK3CD) 114057709(PIK3CB) 114062399(PIK3CA)
FPG: 101911441(PIK3CA) 101919202(PIK3CD) 101923805(PIK3CB)
FCH: 102049197(PIK3CA) 102049812(PIK3CD) 102057414(PIK3CB)
CLV: 102083735(PIK3CB) 102084293(PIK3CA) 102095297(PIK3CD)
EGZ: 104129991(PIK3CA) 104133065(PIK3CD) 104135481(PIK3CB)
NNI: 104008980(PIK3CD) 104019595(PIK3CA) 104023668(PIK3CB)
ACUN: 113483286(PIK3CA) 113483483(PIK3CB) 113487938(PIK3CD)
PADL: 103914966(PIK3CA) 103917840(PIK3CB) 103917969(PIK3CD)
AAM: 106482245(PIK3CA) 106496183(PIK3CB) 106499152(PIK3CD)
ASN: 102372482(PIK3CB) 102387818(PIK3CA) 102388304(PIK3CD)
AMJ: 102564312(PIK3CD) 102571877(PIK3CB) 106737094(PIK3CA)
CPOO: 109308275(PIK3CA) 109308657(PIK3CB) 109314456(PIK3CD) 109317684
GGN: 109288005(PIK3CA) 109288217(PIK3CB) 109293698(PIK3CD)
PSS: 102448624(PIK3CA) 102459577(PIK3CD) 102461096(PIK3CB) 102462482
CMY: 102929971(PIK3CA) 102932183(PIK3CD) 102936956(PIK3CB) 119565006
CPIC: 101934126(PIK3CD) 101935421(PIK3CA) 101940315(PIK3CB)
TST: 117867910(PIK3CD) 117882413(PIK3CA) 117882483(PIK3CB)
CABI: 116819437(PIK3CB) 116821938(PIK3CD) 116826683(PIK3CA)
ACS: 100562345(pik3ca) 100567254(pik3cb) 100567364 100568252(pik3cd)
PVT: 110073252(PIK3CD) 110078719(PIK3CB) 110081909(PIK3CA) 110082359
PBI: 103049546(PIK3CB) 103050043(PIK3CA) 103061550(PIK3CD) 103063682
PMUR: 107284997 107285699(PIK3CA) 107292269(PIK3CB) 107292340(PIK3CD)
TSR: 106541175(PIK3CA) 106545691(PIK3CB)
PGUT: 117676805 117678126(PIK3CD) 117678169(PIK3CA) 117678406(PIK3CB)
PMUA: 114581855 114597773(PIK3CB) 114598008(PIK3CA) 114602471(PIK3CD)
ZVI: 118087296(PIK3CD) 118093522(PIK3CB) 118093528(PIK3CA) 118095035
GJA: 107107376(PIK3CD) 107110507(PIK3CB) 107110982(PIK3CA) 107118085
XLA: 108717120(pik3cb.L) 108718090(pik3ca.S) 108718190(pik3cb.S) 373752(pik3ca.L)
XTR: 100144924(pik3ca) 780390(pik3cb)
NPR: 108785765(PIK3CA) 108796670(PIK3CB) 108798423(PIK3CD)
DRE: 100002263(pik3cb) 394174(pik3cd) 561737(pik3ca)
IPU: 108271155(pik3ca) 108275608 108276156(pik3cd) 108280664(pik3cb)
PHYP: 113525314 113530516(pik3cd) 113533072(pik3ca) 113543185(pik3cb)
AMEX: 103022173(pik3cb) 103032909 103041606(pik3ca) 103045036(pik3cd)
EEE: 113568728(pik3ca) 113581289(pik3cd) 113584997(pik3cb)
TRU: 101066166(pik3ca) 101067191 101068840(pik3cb) 101072152 101076867(pik3cd)
ELY: 117253448 117258562(pik3cd) 117259836(pik3cb) 117271943
PLEP: 121942910(pik3cb) 121947071(pik3cd) 121951130 121963985
SLUC: 116038100 116038947(pik3cb) 116040928(pik3cd) 116046126 116067149(zgc:158659)
PFLV: 114545581 114552427(pik3cb) 114558791(pik3cd) 114561210(pik3ca) 114565044
GAT: 120815991 120820925(pik3cb) 120822125(zgc:158659) 120823571 120829803(pik3cd)
MSAM: 119883088(pik3cb) 119900335 119902325 119905617(pik3cd) 119912407(zgc:158659)
CUD: 121504454(zgc:158659) 121512039 121517765(pik3cd) 121519829 121521620(pik3cb)
OAU: 116309708(pik3cd) 116315474(pik3ca) 116320408 116321621(pik3cb) 116327817(zgc:158659)
OLA: 101161626(pik3ca) 101161887(pik3cd) 101165660(pik3cb) 101168152
OML: 112136442(pik3cb) 112147412 112150459 112159170(pik3cd)
PRET: 103463230(pik3ca) 103467210(pik3cd) 103474947(pik3cb) 103475907 103479066
CVG: 107082599 107082662(pik3cb) 107086882(pik3cd) 107096583(pik3ca) 107102211
CTUL: 119782549 119786919(pik3cb) 119789890(pik3ca) 119796610 119797040(pik3cd)
NFU: 107372394 107384477 107388064(pik3cb) 107390759(pik3cd) 107392966(pik3ca)
KMR: 108236692(pik3cd) 108238323 108238424 108239366(pik3cb) 108248584(zgc:158659)
CSEM: 103378227(pik3cb) 103385041(pik3cd) 103396148 103396566(pik3ca)
SDU: 111216431(pik3ca) 111219094(pik3cd) 111228886 111232818(pik3cb) 111236831
MALB: 109951867(pik3cb) 109969865(pik3ca) 109971552(pik3cd) 109974067
ELS: 105009929 105025897(pik3ca) 105026926(pik3cd) 105028918 105029118(pik3cb)
SFM: 108921677 108923074 108932407(pik3cb) 108933929(pik3cd) 108937366(pik3ca)
PKI: 111836364 111853393(pik3cd) 111853566 111860453(pik3ca) 111860909(pik3cb)
LOC: 102685070(pik3ca) 102688673(pik3cb) 102691786 102695429(pik3cd)
LCM: 102350948(PIK3CA) 102351332 102351622(PIK3CD) 102359335(PIK3CB)
CMK: 103175241(pik3cb) 103175843(pik3ca) 103184230(pik3cd)
RTP: 109915713(pik3cd) 109915990(pik3cb) 109921900
DME: Dmel_CG4141(Pi3K92E)
DER: 6553598
DSE: 6619237
DSI: Dsimw501_GD20048(Dsim_GD20048)
DAN: 6501103
DSR: 110177240
DPE: 6598691
DMN: 108155590
DWI: 6649394
DAZ: 108620950
DNV: 108660257
DHE: 111600712
DVI: 6629966
MDE: 101900071
LCQ: 111678878
ACOZ: 120949499
AARA: 120905815
AAG: 5576468
AALB: 109397596
CPII: 120414150
AME: 551500
ACER: 107995362
BIM: 100748255
BTER: 100646352
CCAL: 108624026
OBB: 114875937
MGEN: 117229750
NMEA: 116428215
CGIG: 122402559
SOC: 105205485
AEC: 105149725
ACEP: 105620083
PBAR: 105432118
VEM: 105567336
HST: 105189236
DQU: 106746788
CFO: 105253109
FEX: 115234077
LHU: 105678402
PGC: 109855345
OBO: 105281126
PCF: 106789415
NVI: 100115810
CSOL: 105365929
MDL: 103576066
TCA: 657286
DPA: 109538758
AGB: 108908090
NVL: 108565087
APLN: 108732483
PPYR: 116175889
OTU: 111419090
BMOR: 101741278
BMAN: 114241881
MSEX: 115451258
PMAC: 106718395
PPOT: 106104487
PXU: 106128370
PRAP: 110995586
ZCE: 119834797
HAW: 110372682
TNL: 113504471
PXY: 105394660
API: 100160001
DNX: 107164340
AGS: 114130020
RMD: 113551287
BTAB: 109034225
CLEC: 106672893
NLU: 111054338
ZNE: 110828562
CSEC: 111873335
FCD: 110846541
RMP: 119180957
VDE: 111250726
VJA: 111269825
CEL: CELE_B0334.8(age-1)
CBR: CBG02868(Cbr-age-1)
BMY: BM_BM1757(Bma-age-1)
EGL: EGR_03896
NVE: 5513857
ADF: 107327044
AMIL: 114970594
PDAM: 113668155
SPIS: 111332193
DGT: 114517978
AQU: 100640192
MBR: MONBRDRAFT_18656(PI3K-CA_alpha)
DDI: DDB_G0268548(pikF) DDB_G0275011(pikC) DDB_G0278727(pikA) DDB_G0282625(pikG) DDB_G0283081(pikB)
DFA: DFA_00682 DFA_02787(pikB) DFA_06196(pikC) DFA_10225(pikF) DFA_11886(pikA)
EHI: EHI_006130(83.t00026) EHI_095130(269.t00003) EHI_188970(67.t00015)
EHX: EMIHUDRAFT_632222(PI3K1)
 » show all
Reference
PMID:7713498
  Authors
Volinia S, Hiles I, Ormondroyd E, Nizetic D, Antonacci R, Rocchi M, Waterfield MD
  Title
Molecular cloning, cDNA sequence, and chromosomal localization of the human phosphatidylinositol 3-kinase p110 alpha (PIK3CA) gene.
  Journal
Genomics 24:472-7 (1994)
DOI:10.1006/geno.1994.1655
  Sequence
[hsa:5290]
Reference
PMID:8246984
  Authors
Hu P, Mondino A, Skolnik EY, Schlessinger J
  Title
Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85.
  Journal
Mol Cell Biol 13:7677-88 (1993)
DOI:10.1128/MCB.13.12.7677
  Sequence
[hsa:5291]
Reference
PMID:9113989
  Authors
Vanhaesebroeck B, Welham MJ, Kotani K, Stein R, Warne PH, Zvelebil MJ, Higashi K, Volinia S, Downward J, Waterfield MD
  Title
P110delta, a novel phosphoinositide 3-kinase in leukocytes.
  Journal
Proc Natl Acad Sci U S A 94:4330-5 (1997)
DOI:10.1073/pnas.94.9.4330
  Sequence
[hsa:5293]
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