KEGG   ORTHOLOGY: K03030
Entry
K03030                      KO                                     

Name
PSMD14, RPN11, POH1
Definition
26S proteasome regulatory subunit N11
Pathway
ko03050  Proteasome
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05169  Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
   05012 Parkinson disease
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
   05014 Amyotrophic lateral sclerosis
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
   05016 Huntington disease
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
   05017 Spinocerebellar ataxia
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
   03051 Proteasome
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M67
   K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   JAMM
    K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
Proteasome [BR:ko03051]
 Eukaryotic proteasome
  Regulatory particles
   PA700 (19S proteasome)
    non-ATPase subunits
     K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11
Genes
HSA: 10213(PSMD14)
PTR: 459686(PSMD14)
PPS: 100984914(PSMD14)
GGO: 101138770(PSMD14)
PON: 100435593(PSMD14)
NLE: 100603884(PSMD14)
MCC: 701063(PSMD14)
MCF: 102130095(PSMD14)
CSAB: 103217175(PSMD14)
RRO: 104666029(PSMD14)
RBB: 108517714(PSMD14)
CJC: 100394741(PSMD14)
SBQ: 101043814(PSMD14)
MMU: 59029(Psmd14)
MCAL: 110312429(Psmd14)
MPAH: 110318110(Psmd14)
RNO: 311078(Psmd14)
MUN: 110539381(Psmd14)
CGE: 100764392(Psmd14)
NGI: 103744087(Psmd14)
HGL: 101697286(Psmd14)
CCAN: 109692595(Psmd14)
OCU: 100339897(PSMD14)
TUP: 102480922(PSMD14)
CFA: 478765(PSMD14)
VVP: 112916468(PSMD14)
AML: 100484033(PSMD14)
UMR: 103659502(PSMD14)
UAH: 113250841(PSMD14)
ORO: 101379161(PSMD14)
ELK: 111140976
FCA: 101095118(PSMD14)
PTG: 102972721(PSMD14)
PPAD: 109271912(PSMD14)
AJU: 106984610(PSMD14)
BTA: 535683(PSMD14)
BOM: 102287909(PSMD14)
BIU: 109567114(PSMD14)
BBUB: 102396548(PSMD14)
CHX: 102185511(PSMD14)
OAS: 101108368(PSMD14)
SSC: 100156327(PSMD14)
CFR: 102517910(PSMD14)
CDK: 105093692(PSMD14)
BACU: 103012608(PSMD14)
LVE: 103068356(PSMD14)
OOR: 101275060(PSMD14)
DLE: 111172793(PSMD14)
PCAD: 102976705(PSMD14)
ECB: 100051409(PSMD14)
EPZ: 103558684(PSMD14)
EAI: 106843144(PSMD14)
MYB: 102251555(PSMD14)
MYD: 102762643(PSMD14)
MNA: 107524548(PSMD14)
HAI: 109379869(PSMD14)
DRO: 112322238(PSMD14)
PALE: 102887112(PSMD14)
RAY: 107499882 107508548(PSMD14)
MJV: 108399181(PSMD14)
LAV: 100664059(PSMD14)
TMU: 101346477
MDO: 100015662(PSMD14)
SHR: 100933723(PSMD14)
PCW: 110220733(PSMD14)
OAA: 100077210(PSMD14)
GGA: 424189(PSMD14)
MGP: 100547734
CJO: 107316984(PSMD14)
NMEL: 110399794(PSMD14)
APLA: 101798276(PSMD14)
ACYG: 106029932(PSMD14)
TGU: 100190290(PSMD14)
LSR: 110468370(PSMD14)
SCAN: 103814385(PSMD14)
GFR: 102039636(PSMD14)
FAB: 101812370(PSMD14)
PHI: 102106606(PSMD14)
PMAJ: 107207584(PSMD14)
CCAE: 111932157(PSMD14)
CCW: 104693930(PSMD14)
ETL: 114054862
FPG: 101910343(PSMD14)
FCH: 102057700(PSMD14)
CLV: 102090448(PSMD14)
EGZ: 104128831
NNI: 104010040(PSMD14)
ACUN: 113482341(PSMD14)
PADL: 103918134(PSMD14)
AAM: 106499266(PSMD14)
ASN: 102374135(PSMD14)
AMJ: 102573107(PSMD14)
PSS: 102461991(PSMD14)
CMY: 102944732(PSMD14)
CPIC: 101952901(PSMD14)
ACS: 100553139(psmd14)
PVT: 110081568(PSMD14)
PBI: 103052409 103057577(PSMD14)
PMUR: 107290161(PSMD14)
TSR: 106540686(PSMD14)
PMUA: 114605552(PSMD14)
GJA: 107126127(PSMD14)
XLA: 380423(psmd14) 444285(psmd14.L)
XTR: 595024(psmd14)
NPR: 108787199(PSMD14)
DRE: 799058(psmd14)
SANH: 107655965 107674508(psmd14)
CCAR: 109053465 109057832(psmd14)
IPU: 100528154(psmd14)
PHYP: 113527075(psmd14)
AMEX: 103034529(psmd14)
EEE: 113582536(psmd14)
TRU: 101079228(psmd14)
LCO: 104918251(psmd14)
NCC: 104967073(psmd14)
MZE: 101472603(psmd14)
ONL: 100701457(psmd14)
OLA: 101158838(psmd14)
XMA: 102225786(psmd14)
XCO: 114143792(psmd14)
PRET: 103462007(psmd14)
CVG: 107082519(psmd14)
NFU: 107381664(psmd14)
KMR: 108249356(psmd14)
ALIM: 106513938(psmd14)
AOCE: 111564850(psmd14)
CSEM: 103378677(psmd14)
POV: 109624874(psmd14)
LCF: 108887970(psmd14)
SDU: 111238662(psmd14)
SLAL: 111652569(psmd14)
HCQ: 109526009(psmd14)
BPEC: 110172933(psmd14)
MALB: 109966277(psmd14) 109972194
SASA: 100196866(psde) 106574401(PSDE)
ELS: 105020011(psmd14)
SFM: 108928981(psmd14)
PKI: 111858408(psmd14)
LCM: 102356448(PSMD14)
CMK: 103176373(psmd14)
RTP: 109932610(psmd14)
CIN: 100179683
SPU: 580426
APLC: 110980412
SKO: 100373887
DME: Dmel_CG18174(Rpn11)
DER: 6540700
DSE: 6613442
DSI: Dsimw501_GD22663(Dsim_GD22663)
DYA: Dyak_GE18698(Dyak_Rpn11)
DAN: 6496984
DSR: 110182352
DPE: 6596517
DMN: 108162355
DWI: 6641631
DAZ: 108611541
DNV: 108649654
DHE: 111599383
DVI: 6628421
MDE: 101895606
LCQ: 111683656
AAG: 5565318
AME: 410072
BIM: 100742704
BTER: 100643880
CCAL: 108631125
OBB: 114878217
SOC: 105194604
MPHA: 105831712
AEC: 105148771
ACEP: 105619909
PBAR: 105425023
VEM: 105566584
HST: 105181511
DQU: 106746828
CFO: 105255429
LHU: 105678507
PGC: 109858577
OBO: 105275292
PCF: 106793031
CSOL: 105364214
MDL: 103575468
TCA: 657072
DPA: 109536784
ATD: 109603914
NVL: 108566610
BMOR: 692958
BMAN: 114251447
PMAC: 106720951
PRAP: 111003501
HAW: 110382794
TNL: 113492787
PXY: 105380111
API: 100159845
DNX: 107167860
AGS: 114133130
RMD: 113555905
BTAB: 109037854
CLEC: 106669254
ZNE: 110830317
FCD: 110852020
PVM: 113800099
TUT: 107366815
CSCU: 111635178
PTEP: 107441349
CEL: CELE_F37A4.5(F37A4.5) CELE_K07D4.3(rpn-11)
CBR: CBG16572 CBG16582 CBG23950(Cbr-rpn-11)
PCAN: 112562903
MYI: 110450608
OBI: 106876959
NVE: 5518465
EPA: 110233831
ADF: 107357475
AMIL: 114966147
PDAM: 113672794
SPIS: 111343635
DGT: 114527523
HMG: 100205738
AQU: 100631943
ATH: AT5G23540
ALY: 9308131
CRB: 17884329
CPAP: 110825793
CIT: 102620341
TCC: 18591239
LJA: Lj0g3v0265709.1(Lj0g3v0265709.1) Lj5g3v0001030.1(Lj5g3v0001030.1) Lj6g3v1966950.1(Lj6g3v1966950.1)
PMUM: 103320312
ZJU: 107420882
RCU: 8278906
JCU: 105633667
VVI: 100247098
SLY: 101259629
SPEN: 107018080
SOT: 102605209
CANN: 107867138
NSY: 104226919
NTO: 104105921
NAU: 109213149
INI: 109153199
LSV: 111885887
CCAV: 112511426
DCR: 108192982
DOSA: Os01t0267200-01(Os01g0267200) Os05t0371200-01(Os05g0371200) Os06t0703600-01(Os06g0703600)
ATS: 109748584(LOC109748584) 109767627(LOC109767627) 109785402(LOC109785402)
SBI: 8074512
DCT: 110114837
CRE: CHLREDRAFT_24132(RPN11)
VCN: VOLCADRAFT_106741(rpn11)
MNG: MNEG_7222
APRO: F751_2407
SCE: YFR004W(RPN11)
ERC: Ecym_7333
KMX: KLMA_70440(RPN11)
NCS: NCAS_0B04720(NCAS0B04720)
NDI: NDAI_0B02130(NDAI0B02130)
TPF: TPHA_0D00710(TPHA0D00710) TPHA_0P00470(TPHA0P00470)
TBL: TBLA_0C00540(TBLA0C00540)
TDL: TDEL_0C01250(TDEL0C01250)
KAF: KAFR_0B01810(KAFR0B01810)
PIC: PICST_32542(RPN11)
CAL: CAALFM_C114460WA(CaO19.7264)
SLB: AWJ20_4864(RPN11)
NCR: NCU00823(rpn-11)
NTE: NEUTE1DRAFT118616(NEUTE1DRAFT_118616)
MGR: MGG_16706
SSCK: SPSK_09493
MAW: MAC_05476
MAJ: MAA_05231
CMT: CCM_00129
MBE: MBM_03927
ANI: AN4492.2
ANG: ANI_1_982064(An07g07860)
PBL: PAAG_12272(PAAG_06740)
ABE: ARB_00298
TVE: TRV_06316
PTE: PTT_14525
ZTR: MYCGRDRAFT_51814(CSN5)
SPO: SPAC31G5.13(rpn11)
CNE: CNA02100
CNB: CNBA2000
TASA: A1Q1_05625
ABP: AGABI1DRAFT113587(AGABI1DRAFT_113587)
ABV: AGABI2DRAFT191764(AGABI2DRAFT_191764)
MGL: MGL_0266
MRT: MRET_1045
DDI: DDB_G0272566(psmD14)
DFA: DFA_00846(psmD14)
EHI: EHI_164750(216.t00002)
PCB: PCHAS_114350(PC300843.00.0)
TAN: TA11850
TPV: TP02_0201
BBO: BBOV_II007480(18.m06620)
CPV: cgd6_3270
SMIN: v1.2.007116.t1(symbB.v1.2.007116.t1)
PTI: PHATRDRAFT_20227(RPN11)
TPS: THAPSDRAFT_33725(RPN11)
SPAR: SPRG_11242
 » show all
Reference
  Authors
Cooper EM, Cutcliffe C, Kristiansen TZ, Pandey A, Pickart CM, Cohen RE
  Title
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1.
  Journal
EMBO J 28:621-31 (2009)
DOI:10.1038/emboj.2009.27
  Sequence
[hsa:10213]
Reference
PMID:9374539
  Authors
Spataro V, Toda T, Craig R, Seeger M, Dubiel W, Harris AL, Norbury C
  Title
Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit.
  Journal
J Biol Chem 272:30470-5 (1997)
DOI:10.1074/jbc.272.48.30470
  Sequence
[hsa:10213]
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