KEGG   ORTHOLOGY: K03283
Entry
K03283                      KO                                     

Name
HSPA1s
Definition
heat shock 70kDa protein 1/2/6/8
Pathway
ko03040  Spliceosome
ko04010  MAPK signaling pathway
ko04141  Protein processing in endoplasmic reticulum
ko04144  Endocytosis
ko04213  Longevity regulating pathway - multiple species
ko04612  Antigen processing and presentation
ko04915  Estrogen signaling pathway
ko05020  Prion disease
ko05134  Legionellosis
ko05145  Toxoplasmosis
ko05162  Measles
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09171 Infectious disease: bacterial
   05134 Legionellosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09172 Infectious disease: viral
   05162 Measles
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03009 Ribosome biogenesis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03110 Chaperones and folding catalysts
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   04131 Membrane trafficking
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03051 Proteasome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
   03029 Mitochondrial biogenesis
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Spliceosome [BR:ko03041]
 Complex B
  Other components
   Prp19 complex
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 Complex C
  Other components
   Prp19-CDC5 complex
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Chaperones and folding catalysts [BR:ko03110]
 Heat shock proteins
  HSP70 / DNAK
   K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Proteasome [BR:ko03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
Other DBs
TC: 1.A.33.1
Genes
HSA: 3303(HSPA1A) 3304(HSPA1B) 3305(HSPA1L) 3306(HSPA2) 3310(HSPA6) 3312(HSPA8)
PTR: 107973291 112205859(HSPA6) 450139(HSPA2) 451629(HSPA8) 471967 745166 748740
PPS: 100974669(HSPA8) 100984890(HSPA2) 100993344(HSPA1L)
GGO: 101128042(HSPA8) 101129102 101131586 101134225 101135640 101147203(HSPA2) 115932977
PON: 100172711(HSPA8) 100172826(HSPA1A) 100454739(HSPA6) 100458051 100461792(HSPA2) 103890872
NLE: 100579396(HSPA8) 100579550(HSPA6) 100594395 100600172(HSPA2) 100605907(HSPA1L) 115832445(HSPA1A)
MCC: 114669856 574271(HSPA2) 707989(HSPA8) 709412 716633 720001(HSPA6) 720054(HSPA1A)
MCF: 101925240 101926012(HSPA1L) 102116937(HSPA2) 102129925 102131294(HSPA8) 102143176(HSPA6)
CSAB: 103221743(HSPA1B) 103221744(HSPA1L) 103221745(HSPA1A) 103223677(HSPA6) 103229169(HSPA2) 103230925 103248693(HSPA8)
RRO: 104656761(HSPA8) 104659427(HSPA1L) 104671954(HSPA6) 104678130 104678425(HSPA2) 115892023
CJC: 100387043(HSPA2) 100389824(HSPA8) 100393753(HSPA1L) 100406069(HSPA1A) 100407165 100411854(HSPA6)
SBQ: 101032912(HSPA8) 101049152(HSPA1A) 101049467(HSPA1L) 101050736(HSPA6) 101052310(HSPA2)
MMU: 15481(Hspa8) 15482(Hspa1l) 15511(Hspa1b) 15512(Hspa2) 193740(Hspa1a)
MPAH: 110324477(Hspa2) 110327293(Hspa8) 110335695(Hspa1l) 110335998
RNO: 108348108(HSP70) 24468(Hspa8) 24472(Hspa1a) 24963(Hspa1l) 294254(Hspa1b) 60460(Hspa2) 689955
MUN: 110547779(Hspa2) 110552032(Hspa8) 110554439(Hspa6) 110560130(Hspa1a) 110560143(Hspa1l)
NGI: 103724426(Hspa1l) 103727922(Hspa8) 103745996 103746770(Hspa6) 103749270(Hspa2)
HGL: 101699805(Hspa1l) 101700637 101701238(Hspa6) 101706305(Hspa2) 101708313(Hspa8)
OCU: 100338160(HSPA6) 100348873(HSPA8) 100352959(HSPA2) 100353534(HSPA1L) 100353783 100354037(HSPA1A) 100354435
TUP: 102475976(HSPA2) 102477173(HSPA1L) 102477588(HSPA1A) 102488085(HSPA8) 102492021 102498690(HSPA6) 102499912
CFA: 403612(HSP70) 474850 479406(HSPA8) 480355(HSPA2)
UMR: 103658293(HSPA6) 103662283(HSPA8) 103672248(HSPA2) 103682293(HSPA1A) 103682294 103682295(HSPA1L)
ORO: 101370862(HSPA8) 101371103(HSPA6) 101375744 101376115(HSPA1L) 101376406 101382556(HSPA2)
FCA: 101087422(HSPA8) 101088003(HSPA2) 101091022
PTG: 102954200(HSPA8) 102957873 102962042 102969535(HSPA2) 102971974(HSPA1L) 102972455(HSPA1B)
AJU: 106971332(HSPA2) 106976665(HSPA8) 106983502 106983975(HSPA1L) 113597921
BTA: 281827(HSPA2) 281831(HSPA8) 282254(HSPA1A) 539835(HSPA6) 540190(HSPA1L)
BOM: 102273821(HSPA6) 102273898(HSPA8) 102273909(HSPA2) 102278697 102278977 102285944(HSPA1L)
BIU: 109565247(HSPA2) 109569622(HSPA8) 109577025 109577026 109578169(HSPA6)
BBUB: 102408332(HSPA1L) 102409533 102411242(HSPA8) 102411459(HSPA2) 102411924 102411960(HSPA6)
CHX: 100860849(HSP70.1) 102177850(HSPA1L) 102178315(HSP70) 102182240(HSPA8) 102185412(HSPA6) 102186695(HSPA2)
OAS: 100913152(HSPA1A) 101107064(HSPA6) 101110063(HSPA2) 101112844(HSPA8) 101117117(HSPA1L) 114108605
SSC: 100144518(HSPA1L) 100511890(HSPA8) 100621324(HSPA2) 396648(HSP70.2) 396906(HSPA6)
CFR: 102516558(HSPA6) 102517440(HSPA1L) 102517682 102521559(HSPA8) 102524235(HSPA2) 116658237
BACU: 103008337(HSPA8) 103018136(HSPA2) 103019729 103020014 103020298(HSPA1L)
ECB: 100009679(HSPA8) 100050827(HSPA1A) 100050904 100051595(HSPA6) 100629616(HSPA2) 111769297
EPZ: 103540615 103540859(HSPA6) 103549908(HSPA8) 103559578(HSPA2) 103562493(HSPA1L) 103563286(HSPA1B)
EAI: 106822285 106825061(HSPA1L) 106831112(HSPA6) 106832775(HSPA8) 106840113(HSPA2)
MYB: 102238827(HSPA1A) 102239414(HSPA2) 102239444(HSPA1L) 102256875(HSPA8)
MYD: 102753664(HSPA2) 102764580(HSPA1L) 102764862 102772438 102774775(HSPA8)
PALE: 102880048(HSPA1B) 102880428(HSPA2) 102880632 102893956(HSPA8) 112469030
RAY: 107498469(HSPA1A) 107498470 107498471 107503644(HSPA8) 107509320(HSPA2)
LAV: 100654015(HSPA2) 100656420(HSPA6) 100663257(HSPA8) 100669335(HSPA1A) 100669618 104847136
GGA: 395853(HSPA8) 423504(HSPA2)
MGP: 100541049(HSPA2) 100551334(HSPA8)
CJO: 107315362(HSPA2) 107324229(HSPA8)
NMEL: 110387614(HSPA8) 110401042(HSPA2)
APLA: 101797658(HSPA2) 101801738(HSPA8)
ACYG: 106037266(HSPA2) 106039820(HSPA8)
TGU: 100220962(HSPA2) 100228250(HSPA8)
LSR: 110476561(HSPA8) 110484074(HSPA2)
SCAN: 103823628(HSPA8) 103826375(HSPA2)
GFR: 102038485(HSPA2) 102044992(HSPA8)
FAB: 101809079(HSPA8) 101819046(HSPA2)
PHI: 102102555(HSPA2) 102108461(HSPA8)
PMAJ: 107205698(HSPA2) 107214420(HSPA8)
CCAE: 111929737(HSPA2) 111939329(HSPA8)
CCW: 104687127(HSPA2) 104692112(HSPA8)
ETL: 114063204(HSPA2) 114069869(HSPA8) 114073255
FPG: 101910891(HSPA2) 101911978(HSPA8)
FCH: 102055493(HSPA8) 102056713(HSPA2)
CLV: 102086356(HSPA8) 102092474(HSPA2)
EGZ: 104129209(HSPA8) 104131661(HSPA2)
NNI: 104010138(HSPA2) 104016627(HSPA8)
ACUN: 113480714(HSPA2) 113488543(HSPA8)
PADL: 103924231(HSPA2) 103924822(HSPA8)
AAM: 106483007(HSPA2) 106486146 106490234(HSPA8)
CMY: 102932086(HSPA8) 102932979
ACS: 100551584(hspa2) 100554002(hspa1a) 100554196 100554364 100564397(hspa8)
XLA: 100037033(hspa1b.L) 100337574(hsc70.ii) 100381020(hspa1a.S) 108696811 379319(hspa8.L) 379760(hspa1l.S) 398343(hsp70.L) 444468(hspa2.L)
XTR: 100037899(hsp70) 100485441(hspa1b) 100488052(hspa1a) 100496320(hspa8) 100496396(hspa2) 779883(hspa1l)
DRE: 100126123(hsp70.1) 100535101(hsp70.2) 30671(hsp70.3) 393586(hsc70) 560210(hsp70l) 562935(hspa8b) 573376(hspa8) 798846(hspa1b)
CIN: 100187210 619232(hsp70)
DME: Dmel_CG18743(Hsp70Ab) Dmel_CG31359(Hsp70Bb) Dmel_CG31366(Hsp70Aa) Dmel_CG31449(Hsp70Ba) Dmel_CG4264(Hsc70-4) Dmel_CG5436(Hsp68) Dmel_CG5834 Dmel_CG6489(Hsp70Bc) Dmel_CG7756(Hsc70-2) Dmel_CG8937(Hsc70-1)
DSI: Dsimw501_GD14466(Dsim_GD14466) Dsimw501_GD18326(Dsim_Hsp68) Dsimw501_GD18878(Dsim_GD18878) Dsimw501_GD18998(Dsim_Hsc70-4) Dsimw501_GD20560(Dsim_Hsp70Ba) Dsimw501_GD20621(Dsim_Hsp70Aa)
AME: 409418(Hsc70-4) 410620
BMOR: 100862772 101735832 101740629 101744922 692436(Hsc70-4) 692822(Hsp70) 733093(Hsp-70)
CEL: CELE_C12C8.1(hsp-70) CELE_F11F1.1(F11F1.1) CELE_F26D10.3(hsp-1) CELE_F44E5.4(F44E5.4) CELE_F44E5.5(F44E5.5)
BMY: Bm1_43675
SHX: MS3_11411
DGT: 114517503
HMG: 100203215 100203304(hsp70)
ATH: AT1G16030(Hsp70b) AT1G56410(ERD2) AT3G09440 AT3G12580(HSP70) AT4G24280(cpHsc70-1) AT5G02490(Hsp70-2) AT5G02500(HSC70-1) AT5G49910(cpHsc70-2)
LJA: Lj0g3v0048139.1(Lj0g3v0048139.1) Lj0g3v0059009.1(Lj0g3v0059009.1) Lj0g3v0059079.1(Lj0g3v0059079.1) Lj0g3v0059099.1(Lj0g3v0059099.1) Lj0g3v0059109.1(Lj0g3v0059109.1) Lj0g3v0059119.1(Lj0g3v0059119.1) Lj0g3v0081039.1(Lj0g3v0081039.1) Lj0g3v0116859.1(Lj0g3v0116859.1) Lj0g3v0188709.1(Lj0g3v0188709.1) Lj0g3v0197419.1(Lj0g3v0197419.1) Lj0g3v0209669.1(Lj0g3v0209669.1) Lj0g3v0211099.1(Lj0g3v0211099.1) Lj0g3v0211119.1(Lj0g3v0211119.1) Lj0g3v0256479.1(Lj0g3v0256479.1) Lj0g3v0273329.1(Lj0g3v0273329.1) Lj0g3v0273339.2(Lj0g3v0273339.2) Lj0g3v0273359.1(Lj0g3v0273359.1) Lj0g3v0291079.1(Lj0g3v0291079.1) Lj0g3v0318919.1(Lj0g3v0318919.1) Lj1g3v2448130.1(Lj1g3v2448130.1) Lj1g3v2580570.1(Lj1g3v2580570.1) Lj1g3v3137770.1(Lj1g3v3137770.1) Lj1g3v3137780.1(Lj1g3v3137780.1) Lj1g3v3137820.1(Lj1g3v3137820.1) Lj1g3v3137820.2(Lj1g3v3137820.2) Lj1g3v3137820.3(Lj1g3v3137820.3) Lj1g3v3217890.1(Lj1g3v3217890.1) Lj1g3v3218000.2(Lj1g3v3218000.2) Lj1g3v3218140.1(Lj1g3v3218140.1) Lj1g3v3219230.1(Lj1g3v3219230.1) Lj1g3v3219240.1(Lj1g3v3219240.1) Lj1g3v3458490.1(Lj1g3v3458490.1) Lj1g3v3718110.1(Lj1g3v3718110.1) Lj1g3v3718120.2(Lj1g3v3718120.2) Lj1g3v3718120.3(Lj1g3v3718120.3) Lj1g3v3718120.4(Lj1g3v3718120.4) Lj1g3v4550110.1(Lj1g3v4550110.1) Lj1g3v4865370.1(Lj1g3v4865370.1) Lj2g3v0915000.1(Lj2g3v0915000.1) Lj2g3v0915010.1(Lj2g3v0915010.1) Lj2g3v0915010.2(Lj2g3v0915010.2) Lj3g3v2062810.1(Lj3g3v2062810.1) Lj3g3v3188570.1(Lj3g3v3188570.1) Lj4g3v0119610.1(Lj4g3v0119610.1) Lj4g3v0451110.1(Lj4g3v0451110.1) Lj4g3v2000880.1(Lj4g3v2000880.1) Lj6g3v1966850.1(Lj6g3v1966850.1) Lj6g3v1966930.1(Lj6g3v1966930.1) Lj6g3v1966930.2(Lj6g3v1966930.2)
DOSA: Os01t0688900-00(Os01g0688900) Os01t0840100-01(Os01g0840100) Os03t0276500-01(Os03g0276500) Os03t0276800-01(Os03g0276800) Os03t0277300-01(Os03g0277300) Os03t0821100-01(Os03g0821100) Os05t0303000-01(Os05g0303000) Os05t0460000-01(Os05g0460000) Os11t0187500-01(Os11g0187500) Os11t0187600-01(Os11g0187600) Os11t0703900-01(Os11g0703900) Os12t0244100-01(Os12g0244100)
ATS: 109736734(LOC109736734) 109741152(LOC109741152) 109745079(LOC109745079) 109747067(LOC109747067) 109751353(LOC109751353) 109751487(LOC109751487) 109756071(LOC109756071) 109761115(LOC109761115) 109763346(LOC109763346) 109768748(LOC109768748) 109782177(LOC109782177) 109786458(LOC109786458) 109787241(LOC109787241) 109787315(LOC109787315)
OLU: OSTLU_28169(HSP70A) OSTLU_32019(HSP70G) OSTLU_48839(HSP70B)
SCE: YAL005C(SSA1) YBL075C(SSA3) YDL229W(SSB1) YER103W(SSA4) YLL024C(SSA2) YNL209W(SSB2)
KMX: KLMA_20459(SSA2) KLMA_50592(SSB) KLMA_80367(SSA3)
NCS: NCAS_0A14440(NCAS0A14440) NCAS_0C05760(NCAS0C05760) NCAS_0D00240(NCAS0D00240) NCAS_0E02580(NCAS0E02580) NCAS_0G01560(NCAS0G01560)
NDI: NDAI_0A01600(NDAI0A01600) NDAI_0E04150(NDAI0E04150) NDAI_0F03620(NDAI0F03620) NDAI_0H00350(NDAI0H00350) NDAI_0H03900(NDAI0H03900)
TPF: TPHA_0E00830(TPHA0E00830) TPHA_0K02090(TPHA0K02090) TPHA_0O01770(TPHA0O01770) TPHA_0P01620(TPHA0P01620)
TBL: TBLA_0B00320(TBLA0B00320) TBLA_0D00580(TBLA0D00580) TBLA_0E01600(TBLA0E01600)
TDL: TDEL_0A00840(TDEL0A00840) TDEL_0C01500(TDEL0C01500) TDEL_0F01620(TDEL0F01620)
KAF: KAFR_0A07780(KAFR0A07780) KAFR_0F00250(KAFR0F00250) KAFR_0I01380(KAFR0I01380) KAFR_0K01860(KAFR0K01860)
PIC: PICST_28757(HSP70.4) PICST_28758(HSP70.6) PICST_38489(HSP70.3) PICST_45857(HSP70.2) PICST_79362(HSP70.1) PICST_80761(SSA2.2) PICST_84662(SSA2.1)
SLB: AWJ20_4148(SSA3) AWJ20_898(SSB2)
NCR: NCU02075(hsp70-2) NCU09602(hsp70-1)
NTE: NEUTE1DRAFT117606(NEUTE1DRAFT_117606) NEUTE1DRAFT132552(NEUTE1DRAFT_132552)
ANI: AN5129.2
ANG: ANI_1_1254144(An16g09260) ANI_1_2038104(An12g06890) ANI_1_2182064(An07g09990)
PNO: SNOG_04404 SNOG_14322(SNOG_14320 SNOG_14321)
SPO: SPAC13G7.02c(ssa1) SPBC1709.05(sks2) SPCC1739.13(ssa2)
ABP: AGABI1DRAFT111531(AGABI1DRAFT_111531) AGABI1DRAFT43082(AGABI1DRAFT_43082) AGABI1DRAFT82477(AGABI1DRAFT_82477)
ABV: AGABI2DRAFT133986(hspB) AGABI2DRAFT190759(hspA) AGABI2DRAFT79769(AGABI2DRAFT_79769)
EHI: EHI_002560(418.t00001) EHI_021780 EHI_052860(218.t00008) EHI_104330(38.t00041) EHI_113410(7.t00068) EHI_150770(584.t00001) EHI_155490(71.t00020) EHI_180380 EHI_188610 EHI_192440(69.t00034) EHI_192510(69.t00023) EHI_198320(278.t00009) EHI_201260(136.t00006)
PCB: PCHAS_072100(PC000186.01.0)
TAN: TA11610
TPV: TP02_0148
BBO: BBOV_I003440(19.m02281) BBOV_III010010(17.m07869)
CPV: cgd2_20
TGO: TGME49_273760(HSP70)
SMIN: v1.2.008389.t1(symbB.v1.2.008389.t1) v1.2.014797.t1(symbB.v1.2.014797.t1) v1.2.016332.t1(symbB.v1.2.016332.t1) v1.2.025479.t1(symbB.v1.2.025479.t1) v1.2.025480.t1(symbB.v1.2.025480.t1) v1.2.026931.t1(symbB.v1.2.026931.t1) v1.2.026932.t1(symbB.v1.2.026932.t1) v1.2.026932.t2(symbB.v1.2.026932.t2) v1.2.026932.t3(symbB.v1.2.026932.t3) v1.2.026933.t1(symbB.v1.2.026933.t1) v1.2.026933.t2(symbB.v1.2.026933.t2) v1.2.033454.t1(symbB.v1.2.033454.t1) v1.2.033563.t1(symbB.v1.2.033563.t1) v1.2.034398.t1(symbB.v1.2.034398.t1) v1.2.039109.t1(symbB.v1.2.039109.t1) v1.2.041606.t1(symbB.v1.2.041606.t1)
PTI: PHATRDRAFT_54019(HSP70A)
 » show all
Reference
PMID:3931075
  Authors
Hunt C, Morimoto RI
  Title
Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.
  Journal
Proc Natl Acad Sci U S A 82:6455-9 (1985)
DOI:10.1073/pnas.82.19.6455
  Sequence
[hsa:3303 3304]
Reference
  Authors
Mayer MP, Bukau B
  Title
Hsp70 chaperones: cellular functions and molecular mechanism.
  Journal
Cell Mol Life Sci 62:670-84 (2005)
DOI:10.1007/s00018-004-4464-6
Reference
  Authors
Perez-Vargas J, Romero P, Lopez S, Arias CF
  Title
The peptide-binding and ATPase domains of recombinant hsc70 are required to interact with rotavirus and reduce its infectivity.
  Journal
J Virol 80:3322-31 (2006)
DOI:10.1128/JVI.80.7.3322-3331.2006
  Sequence
[hsa:3303 3304]
LinkDB

KEGG   ORTHOLOGY: K09542
Entry
K09542                      KO                                     

Name
CRYAB
Definition
crystallin, alpha B
Pathway
ko04141  Protein processing in endoplasmic reticulum
ko04213  Longevity regulating pathway - multiple species
Disease
H00595  Myofibrillar myopathies
H01202  Cataract
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K09542  CRYAB; crystallin, alpha B
 09150 Organismal Systems
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    K09542  CRYAB; crystallin, alpha B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K09542  CRYAB; crystallin, alpha B
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K09542  CRYAB; crystallin, alpha B
Chaperones and folding catalysts [BR:ko03110]
 Heat shock proteins
  HSP20
   K09542  CRYAB; crystallin, alpha B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K09542  CRYAB; crystallin, alpha B
Genes
HSA: 1410(CRYAB)
PTR: 451543(CRYAB)
PPS: 100972736(CRYAB)
GGO: 101136194(CRYAB)
PON: 100172850(CRYAB)
NLE: 100579972(CRYAB)
MCC: 710747(CRYAB)
MCF: 102128339(CRYAB)
CSAB: 103248454(CRYAB)
RRO: 104677346(CRYAB)
RBB: 108536457(CRYAB)
CJC: 100410127(CRYAB)
SBQ: 101030584(CRYAB)
MMU: 12955(Cryab)
MCAL: 110301096(Cryab)
MPAH: 110327474(Cryab)
RNO: 25420(Cryab)
MUN: 110562018(Cryab)
CGE: 100772623(Cryab)
NGI: 103733886(Cryab)
HGL: 101696917(Cryab)
CCAN: 109694053(Cryab)
OCU: 100009295(CRYAB)
TUP: 102481409(CRYAB)
CFA: 479441(CRYAB)
VVP: 112925981(CRYAB)
AML: 100479594(CRYAB)
UMR: 103662396(CRYAB)
UAH: 113260065(CRYAB)
ORO: 101364850(CRYAB)
ELK: 111153702
FCA: 101092640(CRYAB)
PTG: 102957252(CRYAB)
PPAD: 109278656(CRYAB)
AJU: 106984133(CRYAB)
BTA: 281719(CRYAB)
BOM: 102284064(CRYAB)
BIU: 109569661(CRYAB)
BBUB: 102407581(CRYAB)
CHX: 102171725(CRYAB)
OAS: 497274(CRYAB)
SSC: 100519789(CRYAB)
CFR: 102506084(CRYAB)
CDK: 105094033(CRYAB)
BACU: 103017336(CRYAB)
LVE: 103090860(CRYAB)
OOR: 101274522(CRYAB)
DLE: 111168054(CRYAB)
PCAD: 102994900(CRYAB)
ECB: 100061921(CRYAB)
EPZ: 103555602(CRYAB)
EAI: 106840211(CRYAB)
MYB: 102255821(CRYAB)
MYD: 102766063(CRYAB)
MNA: 107531294(CRYAB)
HAI: 109388715(CRYAB)
DRO: 112314304(CRYAB)
PALE: 102887587(CRYAB)
RAY: 107512973(CRYAB)
MJV: 108396505(CRYAB)
LAV: 100666383(CRYAB)
TMU: 101345815
MDO: 100026448(CRYAB)
SHR: 100917410(CRYAB)
PCW: 110210687(CRYAB)
OAA: 791109(CRYAB)
GGA: 396089(CRYAB)
MGP: 100548878(CRYAB)
CJO: 107324124(CRYAB)
NMEL: 110387574(CRYAB)
APLA: 101800794(CRYAB)
ACYG: 106039817(CRYAB)
TGU: 100230097(CRYAB)
LSR: 110470462(CRYAB)
SCAN: 103822989(CRYAB)
GFR: 102040461(CRYAB)
FAB: 101817304(CRYAB)
PHI: 102104361(CRYAB)
PMAJ: 107214498(CRYAB)
CCAE: 111939288(CRYAB)
CCW: 104692085(CRYAB)
ETL: 114067831(CRYAB)
FPG: 101925001(CRYAB)
FCH: 102053641(CRYAB)
CLV: 102097634(CRYAB)
EGZ: 104125913(CRYAB)
NNI: 104019050(CRYAB)
ACUN: 113488568(CRYAB)
PADL: 103921549(CRYAB)
AAM: 106495949(CRYAB)
ASN: 102388352(CRYAB)
AMJ: 102560260(CRYAB)
PSS: 102447067(HSPB6) 102460134(CRYAB)
CMY: 102948201(CRYAB)
CPIC: 101934775(CRYAB) 101946822(HSPB6)
ACS: 100554777(cryab) 100556405(hspb6)
PVT: 110078645(CRYAB) 110089904(HSPB6)
PBI: 103048445(CRYAB) 103058231(HSPB6)
PMUR: 107284519(CRYAB) 107287998(HSPB6)
TSR: 106540432(CRYAB) 106552486
PMUA: 114585146(CRYAB) 114590273 114598379 114603570(HSPB6)
GJA: 107108175(HSPB6) 107114149(CRYAB)
XLA: 108696488(cryab.L) 108697581(cryab.S) 446313(hspb6.L)
XTR: 100494296(hspb6) 100494321(cryab)
NPR: 108793089(CRYAB) 108800002(HSPB6)
DRE: 30393(cryaba)
IPU: 108259721 108277601(cryaba)
PHYP: 113531264
AMEX: 103028220(cryab)
EEE: 113591352(cryab)
TRU: 101066139 101076268(hspb6)
LCO: 104929925(cryab)
NCC: 104964648(cryab)
MZE: 101483818
ONL: 100709337
OLA: 101169800 101172926(hspb6)
XMA: 102229423 102236640(hspb6)
XCO: 114141923(hspb6) 114153574
PRET: 103475461 103478516(hspb6)
CVG: 107086141(hspb6) 107089805
NFU: 107372440(hspb6)
KMR: 108236942
ALIM: 106514070(cryab) 106517701(hspb6)
AOCE: 111580654
CSEM: 103395687
POV: 109628363
LCF: 108894016
SDU: 111234058(hspb6) 111234403
SLAL: 111665013(hspb6) 111666173
HCQ: 109517903 109525660(hspb6)
MALB: 109959280(cryab) 109971695(hspb6)
SASA: 100194524(hspb6l) 106577983
SALP: 111964872
ELS: 105019112
SFM: 108936023(cryab)
PKI: 111844776(cryab)
LCM: 102364930(CRYAB) 106704085(HSPB6)
CMK: 103190737(cryab)
RTP: 109930998(cryab)
SPU: 578820
APLC: 110981314
DME: Dmel_CG4533(l(2)efl)
DER: 6547866
DSE: 6615753
DSI: Dsimw501_GD25025(Dsim_GD25025)
DAN: 6494691
DSR: 110177056
DPE: 6592523
DWI: 6652437
DAZ: 108616566
DNV: 108654377
DHE: 111593805
DVI: 6625577
MDE: 101896196(hsp20)
LCQ: 111683801
API: 100169331
DNX: 107172057
AGS: 114123128
RMD: 113549841
PVM: 113827261
CBR: CBG02254 CBG04606 CBG11272(Cbr-hsp-17) CBG16680(Cbr-hsp-12.2) CBG21659(Cbr-hsp-12.3) CBG24755
TSP: Tsp_08015
LAK: 106171908
EPA: 110241970
ADF: 107346285
AMIL: 114957795
PDAM: 113664410
SPIS: 111337819
 » show all
Reference
  Authors
Derham BK, Harding JJ
  Title
Alpha-crystallin as a molecular chaperone.
  Journal
Prog Retin Eye Res 18:463-509 (1999)
DOI:10.1016/S1350-9462(98)00030-5
  Sequence
[hsa:1410]
LinkDB

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