KEGG   ORTHOLOGY: K03347
Entry
K03347                      KO                                     

Name
CUL1, CDC53
Definition
cullin 1
Pathway
ko04110  Cell cycle
ko04111  Cell cycle - yeast
ko04114  Oocyte meiosis
ko04120  Ubiquitin mediated proteolysis
ko04141  Protein processing in endoplasmic reticulum
ko04310  Wnt signaling pathway
ko04340  Hedgehog signaling pathway
ko04341  Hedgehog signaling pathway - fly
ko04350  TGF-beta signaling pathway
ko04710  Circadian rhythm
ko05131  Shigellosis
ko05170  Human immunodeficiency virus 1 infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03347  CUL1, CDC53; cullin 1
   04120 Ubiquitin mediated proteolysis
    K03347  CUL1, CDC53; cullin 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K03347  CUL1, CDC53; cullin 1
   04340 Hedgehog signaling pathway
    K03347  CUL1, CDC53; cullin 1
   04341 Hedgehog signaling pathway - fly
    K03347  CUL1, CDC53; cullin 1
   04350 TGF-beta signaling pathway
    K03347  CUL1, CDC53; cullin 1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03347  CUL1, CDC53; cullin 1
   04111 Cell cycle - yeast
    K03347  CUL1, CDC53; cullin 1
   04114 Oocyte meiosis
    K03347  CUL1, CDC53; cullin 1
 09150 Organismal Systems
  09159 Environmental adaptation
   04710 Circadian rhythm
    K03347  CUL1, CDC53; cullin 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03347  CUL1, CDC53; cullin 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03347  CUL1, CDC53; cullin 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03347  CUL1, CDC53; cullin 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03347  CUL1, CDC53; cullin 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Cullin
     K03347  CUL1, CDC53; cullin 1
Other DBs
COG: COG5647
Genes
HSA: 8454(CUL1)
PTR: 463821(CUL1)
PPS: 100972042(CUL1)
GGO: 109025459(CUL1)
NLE: 100580180(CUL1)
MCC: 710581(CUL1)
MCF: 101867010(CUL1)
CSAB: 103227180(CUL1)
RRO: 104667014(CUL1)
RBB: 108522304(CUL1)
CJC: 100395702(CUL1)
SBQ: 101051291(CUL1)
MMU: 26965(Cul1)
MCAL: 110296040(Cul1)
MPAH: 110316251(Cul1)
RNO: 362356(Cul1)
MUN: 110547501(Cul1)
CGE: 100757763(Cul1)
NGI: 103731381(Cul1)
HGL: 101703786(Cul1)
CCAN: 109695511(Cul1)
OCU: 100345752(CUL1)
TUP: 102497446(CUL1)
CFA: 475512(CUL1)
VVP: 112934801(CUL1)
AML: 100466596(CUL1)
UMR: 103668956(CUL1)
UAH: 113241451(CUL1)
ORO: 101369645(CUL1)
ELK: 111154336
FCA: 101087051(CUL1)
PTG: 102957061(CUL1)
PPAD: 109269217(CUL1)
AJU: 106981418(CUL1)
BTA: 407228(CUL1)
BOM: 102277514
BIU: 109557757(CUL1)
BBUB: 102400493(CUL1)
CHX: 102189276(CUL1)
OAS: 101106584(CUL1)
SSC: 100524037(CUL1)
CFR: 102517054(CUL1)
CDK: 105085195(CUL1)
BACU: 103011656(CUL1)
LVE: 103070988(CUL1)
OOR: 101280362(CUL1)
DLE: 111177194(CUL1)
ECB: 100051217(CUL1)
EPZ: 103553705(CUL1)
EAI: 106842121(CUL1)
MYB: 102245795(CUL1)
MYD: 102771406(CUL1)
MNA: 107523767(CUL1)
HAI: 109395450(CUL1)
DRO: 112308266(CUL1)
PALE: 102887109(CUL1)
RAY: 107500535(CUL1)
MJV: 108386656(CUL1)
LAV: 100664600(CUL1)
TMU: 101360163
MDO: 100013348(CUL1)
SHR: 100926417(CUL1)
PCW: 110201672(CUL1)
OAA: 100073945(CUL1)
GGA: 420783(CUL1)
MGP: 100540218(CUL1)
CJO: 107309836(CUL1)
NMEL: 110390791(CUL1)
APLA: 101793264(CUL1)
ACYG: 106048734(CUL1)
TGU: 100223849(CUL1)
LSR: 110479185(CUL1)
SCAN: 103819366(CUL1)
GFR: 102038503(CUL1)
FAB: 101810352(CUL1)
PHI: 102100590(CUL1)
PMAJ: 107200314(CUL1)
CCAE: 111923644(CUL1)
CCW: 104688924(CUL1)
ETL: 114063866(CUL1)
FPG: 101911159(CUL1)
FCH: 102056187(CUL1)
CLV: 102093584(CUL1)
EGZ: 104124772(CUL1)
NNI: 104015389(CUL1)
ACUN: 113477562(CUL1)
PADL: 103916089(CUL1)
AAM: 106495275(CUL1)
ASN: 102371987(CUL1)
AMJ: 102562508(CUL1)
PSS: 102452815(CUL1)
CMY: 102932876(CUL1)
CPIC: 101938030(CUL1)
ACS: 100563024(cul1)
PVT: 110088676(CUL1)
PBI: 103051969(CUL1)
PMUR: 107288848
TSR: 106547022(CUL1)
PMUA: 114607913(CUL1)
GJA: 107119625(CUL1)
XLA: 734414(cul1.S) 734526
XTR: 734121(cul1)
NPR: 108794363(CUL1)
DRE: 323883(cul1a) 406816(cul1b)
IPU: 108256454(cul1) 108280768
AMEX: 103026940(cul1) 111194478
EEE: 113584345
TRU: 101068951(cul1)
NCC: 104940785(cul1)
MZE: 101485891(cul1)
ONL: 100699353(cul1)
OLA: 101155471(cul1)
XMA: 102238349(cul1)
XCO: 114136425(cul1)
PRET: 103457010(cul1)
CVG: 107097881(cul1)
NFU: 107383137(cul1)
KMR: 108249552(cul1)
ALIM: 106531655(cul1)
AOCE: 111571338(cul1)
CSEM: 103377187(cul1)
POV: 109645364(cul1)
LCF: 108885000(cul1)
SDU: 111238316(cul1)
SLAL: 111647272(cul1)
HCQ: 109530293(cul1)
BPEC: 110158319(cul1)
MALB: 109951060(cul1)
ELS: 105022041(cul1) 105024245
SFM: 108919683(cul1) 108935504
LCM: 102360768(CUL1)
CMK: 103187003(cul1)
RTP: 109916300(cul1)
BFO: 118403913
SPU: 589630
APLC: 110975971
DME: Dmel_CG11261(Cul6) Dmel_CG1877(Cul1)
DSI: Dsimw501_GD10516(Dsim_GD10516) Dsimw501_GD12683(Dsim_GD12683)
DPE: 6590465
DWI: 6640400
DAZ: 108616909
DNV: 108654970
DHE: 111599944
DVI: 6635882
MDE: 101893739
LCQ: 111682503
AAG: 5578149
AALB: 115258731
PVM: 113816603
TUT: 107366218
CEL: CELE_D2045.6(cul-1) CELE_K08E7.7(cul-6)
PCAN: 112557063
CRG: 105325130
MYI: 110451924
NVE: 5509071
AMIL: 114977368
DGT: 114517451
HMG: 101238456
ALY: 9310976
CRB: 17884026
BRP: 103836734
CPAP: 110821436
VRA: 106768610
VAR: 108346100
CCAJ: 109807764
LJA: Lj0g3v0209709.2(Lj0g3v0209709.2)
FVE: 101303474
RCN: 112197743
CSV: 101216323
CMO: 103497868
MCHA: 111009631
CPEP: 111806899
RCU: 8262419
VVI: 100233054(CUL1) 100261361
SLY: 101249757
SPEN: 107006861
CANN: 107842772
NTA: 107770609 107807954(cul1C)
NSY: 104229650
NTO: 104090935
NAU: 109223502
CCAV: 112529394
BVG: 104886440
SOE: 110791258
DOSA: Os01t0369000-01(Os01g0369000) Os01t0369200-01(Os01g0369200)
ATS: 109738966(LOC109738966) 109765974(LOC109765974)
PDA: 103716049
EGU: 105045249
MUS: 103974412
DCT: 110116436
PEQ: 110037334
AOF: 109849771
ATR: 18422906
SMO: SELMODRAFT_158171(CUL1-2) SELMODRAFT_173394(CUL1-1)
CRE: CHLREDRAFT_116937(CUL3)
APRO: F751_6385
SCE: YDL132W(CDC53)
ERC: Ecym_8046
KMX: KLMA_60494(CDC53)
NCS: NCAS_0A13810(NCAS0A13810)
NDI: NDAI_0A02230(NDAI0A02230)
TPF: TPHA_0P00850(TPHA0P00850)
TBL: TBLA_0A05930(TBLA0A05930)
TDL: TDEL_0H01480(TDEL0H01480)
KAF: KAFR_0B01150(KAFR0B01150)
PIC: PICST_29770(CDC53)
CAL: CAALFM_C301700WA(CDC53)
NCR: NCU05204(cul-1)
NTE: NEUTE1DRAFT80573(NEUTE1DRAFT_80573)
MGR: MGG_07145
SSCK: SPSK_07032
MAW: MAC_08080
MAJ: MAA_05122
CMT: CCM_04213
MBE: MBM_02956
ANI: AN1019.2
ANG: ANI_1_830074(An08g05870)
PBN: PADG_11387(PADG_02155)
ABE: ARB_01462
TVE: TRV_05741
PTE: PTT_04953
SPO: SPAC17G6.12(cul1)
CNE: CNN01140
CNB: CNBN1130
TASA: A1Q1_03354
DDI: DDB_G0267384(culB) DDB_G0278991(culE) DDB_G0291972(culA)
DFA: DFA_09462(culA)
EHI: EHI_156450(100.t00027)
SMIN: v1.2.024830.t1(symbB.v1.2.024830.t1)
PTI: PHATRDRAFT_29317(CUL1_3)
SPAR: SPRG_01077
 » show all
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
DOI:10.1038/nrm1547
Reference
PMID:9499404
  Authors
Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M
  Title
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.
  Journal
Genes Dev 12:692-705 (1998)
DOI:10.1101/gad.12.5.692
  Sequence
[sce:YDL132W]
Reference
PMID:8681378
  Authors
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM
  Title
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
  Journal
Cell 85:829-39 (1996)
DOI:10.1016/S0092-8674(00)81267-2
  Sequence
[hsa:8454]
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