| Entry |
|
|---|
| Name |
2-aminoethylphosphonate---pyruvate transaminase;
(2-aminoethyl)phosphonate transaminase;
(2-aminoethyl)phosphonate aminotransferase;
(2-aminoethyl)phosphonic acid aminotransferase;
2-aminoethylphosphonate-pyruvate aminotransferase;
2-aminoethylphosphonate aminotransferase;
2-aminoethylphosphonate transaminase;
AEP transaminase;
AEPT
|
|---|
| Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
|
|---|
| Sysname |
(2-aminoethyl)phosphonate:pyruvate aminotransferase
|
|---|
| Reaction(IUBMB) |
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine [RN: R04152]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
(2-aminoethyl)phosphonate [CPD: C03557];
pyruvate [CPD: C00022]
|
|---|
| Product |
2-phosphonoacetaldehyde [CPD: C03167];
L-alanine [CPD: C00041]
|
|---|
| Comment |
A pyridoxal-phosphate protein. 2-Aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate.
|
|---|
| History |
EC 2.6.1.37 created 1972, modified 1982, modified 2001
|
|---|
| Pathway |
| ec00440 | Phosphonate and phosphinate metabolism |
| ec01120 | Microbial metabolism in diverse environments |
|
|---|
| Orthology |
| K03430 | 2-aminoethylphosphonate-pyruvate transaminase |
|
|---|
| Genes |
» show all
|
|---|
| Reference |
|
|---|
| Authors |
La Nauze JM, Rosenberg H. |
|---|
| Title |
The identification of 2-phosphonoacetaldehyde as an intermediate in the degradation of 2-aminoethylphosphonate by Bacillus cereus. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Dumora C, Lacoste AM, Cassaigne A. |
|---|
| Title |
Purification and properties of 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Reference |
|
|---|
| Authors |
Lacoste AM, Dumora C, Balas L, Hammerschmidt F, Vercauteren J. |
|---|
| Title |
Stereochemistry of the reaction catalysed by 2-aminoethylphosphonate aminotransferase. A 1H-NMR study. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Reference |
|
|---|
| Authors |
Lacoste AM, Dumora C, Ali BR, Neuzil E, Dixon HB. |
|---|
| Title |
Utilization of 2-aminoethylarsonic acid in Pseudomonas aeruginosa. |
|---|
| Journal |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.6.1.37 |
| ExPASy - ENZYME nomenclature database: | 2.6.1.37 |
|
|---|
| LinkDB |
|
|---|
