KEGG   ORTHOLOGY: K03511
Entry
K03511                      KO                                     

Name
POLK
Definition
DNA polymerase kappa [EC:2.7.7.7]
Pathway
ko03460  Fanconi anemia pathway
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05213  Endometrial cancer
ko05214  Glioma
ko05216  Thyroid cancer
ko05217  Basal cell carcinoma
ko05218  Melanoma
ko05220  Chronic myeloid leukemia
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    K03511  POLK; DNA polymerase kappa
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03511  POLK; DNA polymerase kappa
   05202 Transcriptional misregulation in cancer
    K03511  POLK; DNA polymerase kappa
  09162 Cancer: specific types
   05210 Colorectal cancer
    K03511  POLK; DNA polymerase kappa
   05212 Pancreatic cancer
    K03511  POLK; DNA polymerase kappa
   05225 Hepatocellular carcinoma
    K03511  POLK; DNA polymerase kappa
   05226 Gastric cancer
    K03511  POLK; DNA polymerase kappa
   05214 Glioma
    K03511  POLK; DNA polymerase kappa
   05216 Thyroid cancer
    K03511  POLK; DNA polymerase kappa
   05220 Chronic myeloid leukemia
    K03511  POLK; DNA polymerase kappa
   05217 Basal cell carcinoma
    K03511  POLK; DNA polymerase kappa
   05218 Melanoma
    K03511  POLK; DNA polymerase kappa
   05213 Endometrial cancer
    K03511  POLK; DNA polymerase kappa
   05224 Breast cancer
    K03511  POLK; DNA polymerase kappa
   05222 Small cell lung cancer
    K03511  POLK; DNA polymerase kappa
   05223 Non-small cell lung cancer
    K03511  POLK; DNA polymerase kappa
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K03511  POLK; DNA polymerase kappa
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K03511  POLK; DNA polymerase kappa
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K03511  POLK; DNA polymerase kappa
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  TLS (translesion DNA synthesis) factors
   Y-family DNA polymerases
    K03511  POLK; DNA polymerase kappa
Other DBs
GO: 0016450
Genes
HSA: 51426(POLK)
PTR: 461803(POLK)
PPS: 100989542(POLK)
GGO: 101137568(POLK)
PON: 100443121(POLK)
NLE: 100598341(POLK)
MCC: 705713(POLK)
MCF: 101925142(POLK)
CSAB: 103223255(POLK)
RRO: 104653753(POLK)
RBB: 108513078(POLK)
CJC: 100403269(POLK)
SBQ: 101034259(POLK)
MMU: 27015(Polk)
MCAL: 110308520(Polk)
MPAH: 110329143(Polk)
RNO: 171525(Polk)
CGE: 100758099(Polk)
NGI: 103736569(Polk)
HGL: 101718580(Polk)
CCAN: 109699936
OCU: 100352218(POLK)
TUP: 102479454(POLK)
CFA: 479180(POLK)
VVP: 112919752(POLK)
AML: 100464732(POLK)
UMR: 103663562(POLK)
UAH: 113255198(POLK)
ORO: 101367509(POLK)
ELK: 111148313
FCA: 101099613(POLK)
PTG: 102962803(POLK)
PPAD: 109274988(POLK)
AJU: 106974834(POLK)
BTA: 541218(POLK)
BOM: 102269608(POLK)
BIU: 109564642(POLK)
BBUB: 102395618(POLK)
CHX: 102170426(POLK)
OAS: 101109360(POLK)
SSC: 100518650(POLK)
CFR: 102507560(POLK)
CDK: 105084801(POLK)
BACU: 103009875(POLK)
LVE: 103080788(POLK)
OOR: 101276684(POLK)
DLE: 111185272(POLK)
PCAD: 102976634(POLK)
ECB: 100065534(POLK)
EPZ: 103563108(POLK)
EAI: 106824006(POLK)
MYB: 102263448(POLK)
MYD: 102767828(POLK)
MNA: 107531215(POLK)
HAI: 109381899(POLK)
DRO: 112307522(POLK)
PALE: 102890888(POLK)
RAY: 107506450(POLK)
MJV: 108408163(POLK)
LAV: 100662275(POLK)
TMU: 101359617
MDO: 100014509(POLK)
SHR: 100923657(POLK)
PCW: 110216585(POLK)
OAA: 100077423(POLK)
GGA: 374003(POLK)
CJO: 107306045(POLK)
NMEL: 110390236(POLK)
APLA: 101805175(POLK)
ACYG: 106042914(POLK)
TGU: 100227024(POLK)
LSR: 110471285(POLK)
SCAN: 103819489(POLK)
GFR: 102039498(POLK)
FAB: 101811613(POLK)
PHI: 102102499(POLK)
PMAJ: 107215887(POLK)
CCAE: 111940780(POLK)
CCW: 104685131(POLK)
ETL: 114057125(POLK)
FPG: 101915728(POLK)
FCH: 102051766(POLK)
CLV: 102088557(POLK)
EGZ: 104124862(POLK)
NNI: 104013036(POLK)
ACUN: 113490232(POLK)
PADL: 103919698(POLK)
ASN: 102369446(POLK)
AMJ: 102570348(POLK)
PSS: 102458919(POLK)
CMY: 102929336(POLK)
CPIC: 101932662(POLK)
ACS: 100555251(polk)
PVT: 110084578(POLK)
PBI: 103053639(POLK)
PMUR: 107291180(POLK)
TSR: 106549330(POLK)
PMUA: 114606748(POLK)
GJA: 107118119(POLK)
XLA: 446387(polk.L)
XTR: 448219(polk)
NPR: 108796369(POLK)
DRE: 562749(polk)
SRX: 107755742(polk)
SANH: 107685252(polk)
IPU: 108256008(polk)
PHYP: 113536898(polk)
AMEX: 103046822(polk)
EEE: 113580484(polk)
TRU: 101073091(polk)
LCO: 104929274
NCC: 104956918(polk)
MZE: 101481221(polk)
ONL: 100707059(polk)
OLA: 101163905(polk)
XMA: 102222183(polk)
XCO: 114155133(polk)
PRET: 103470422(polk)
CVG: 107103651(polk)
NFU: 107393897(polk)
KMR: 108234486(polk)
ALIM: 106532864(polk)
AOCE: 111576009(polk)
CSEM: 103398131(polk)
POV: 109638119(polk)
LCF: 108878367(polk)
SDU: 111229321(polk)
SLAL: 111660297(polk)
HCQ: 109514148(polk)
BPEC: 110156764(polk)
MALB: 109957020(polk)
SASA: 106580482
OTW: 112248586(polk) 112262784
SALP: 111958249(polk)
ELS: 105014328(polk)
SFM: 108937976(polk)
PKI: 111850292(polk)
LCM: 102360332(POLK)
CMK: 103186374(polk)
RTP: 109931751(polk)
BFO: 118410304
CIN: 100179616
SPU: 754579
APLC: 110981807
SKO: 102806717
FCD: 110858005
PVM: 113812272
DPTE: 113791123
CSCU: 111622506
PTEP: 107439479
CEL: CELE_F22B7.6(polk-1)
CBR: CBG22922(Cbr-polk-1)
BMY: Bm1_37790
TSP: Tsp_01714
PCAN: 112554490
CRG: 105317179
MYI: 110447414
OBI: 106874111
LAK: 106153638
SHX: MS3_00172
EGL: EGR_01380
EPA: 110233633
ADF: 107356880
AMIL: 114956571
PDAM: 113668989
SPIS: 111338276
DGT: 114520093
HMG: 100197887
ATH: AT1G49980
ALY: 9327609
CRB: 17898321
BRP: 103871374
BOE: 106296363
RSZ: 108810881
THJ: 104803441
CPAP: 110810424
CIT: 102631401
TCC: 18608091
GRA: 105795177
GAB: 108484060
DZI: 111309021
EGR: 104453083
GMX: 100816973
GSJ: 114373987
VRA: 106776979
VAR: 108319976
VUN: 114173172
CCAJ: 109814587
CAM: 101496826
ADU: 107488608
AIP: 107640350
FVE: 101292945
RCN: 112172674
PPER: 18768146
PMUM: 103335090
PAVI: 110763673
MDM: 103436119
ZJU: 107434628
CSV: 101212452
CMO: 103495309
MCHA: 111017350
CMAX: 111470994
CMOS: 111455591
CPEP: 111811256
RCU: 107261922
JCU: 105650782
HBR: 110648690
MESC: 110625340
POP: 7465079
PEU: 105129805
JRE: 108979743
VVI: 100253205
SLY: 101263644
SPEN: 107011472
SOT: 102583515
CANN: 107840178
NSY: 104212531
NTO: 104093115
NAU: 109230901
INI: 109161557
SIND: 105169381
OEU: 111410653
HAN: 110918701
LSV: 111904227
CCAV: 112507989
DCR: 108224801
BVG: 104904866
SOE: 110804934
CQI: 110684985
NNU: 104590383
DOSA: Os03t0616300-01(Os03g0616300)
BDI: 100839865
ZMA: 100381652
PDA: 103709141
EGU: 105032776
MUS: 103983593
ATR: 18430883
CRE: CHLREDRAFT_111898(POLK1)
APRO: F751_1873
NCR: NCU02457
NTE: NEUTE1DRAFT85852(NEUTE1DRAFT_85852)
MGR: MGG_07238
SSCK: SPSK_03129
MAW: MAC_01865
MAJ: MAA_00563
CMT: CCM_05997
MBE: MBM_09134
ANI: AN3373.2
ANG: ANI_1_264104(An12g01930)
ABE: ARB_06262
TVE: TRV_00836
PTE: PTT_09519
SPO: SPCC553.07c(kpa1)
CNE: CNL04490
CNB: CNBI2350
TASA: A1Q1_02062
ABP: AGABI1DRAFT55621(AGABI1DRAFT_55621)
ABV: AGABI2DRAFT69121(AGABI2DRAFT_69121)
MGL: MGL_1557
MRT: MRET_3800
DFA: DFA_07573
SMIN: v1.2.024275.t1(symbB.v1.2.024275.t1)
FCY: FRACYDRAFT_194538(PolKa)
SPAR: SPRG_09244
 » show all
Reference
  Authors
Ogi T, Kato T Jr, Kato T, Ohmori H
  Title
Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB.
  Journal
Genes Cells 4:607-18 (1999)
DOI:10.1046/j.1365-2443.1999.00289.x
  Sequence
[hsa:51426]
Reference
  Authors
Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC
  Title
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene.
  Journal
J Biol Chem 276:92-8 (2001)
DOI:10.1074/jbc.M004413200
  Sequence
[hsa:51426]
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