KEGG   ORTHOLOGY: K03990
Entry
K03990                      KO                                     

Name
C3
Definition
complement component 3
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04145  Phagosome
ko04610  Complement and coagulation cascades
ko04613  Neutrophil extracellular trap formation
ko05131  Shigellosis
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05150  Staphylococcus aureus infection
ko05152  Tuberculosis
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05203  Viral carcinogenesis
ko05322  Systemic lupus erythematosus
Disease
H00102  Classic complement pathway component defects
H00821  Age-related macular degeneration
H01434  Atypical hemolytic uremic syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03990  C3; complement component 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K03990  C3; complement component 3
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03990  C3; complement component 3
   04613 Neutrophil extracellular trap formation
    K03990  C3; complement component 3
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K03990  C3; complement component 3
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K03990  C3; complement component 3
   05168 Herpes simplex virus 1 infection
    K03990  C3; complement component 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K03990  C3; complement component 3
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K03990  C3; complement component 3
   05133 Pertussis
    K03990  C3; complement component 3
   05134 Legionellosis
    K03990  C3; complement component 3
   05150 Staphylococcus aureus infection
    K03990  C3; complement component 3
   05152 Tuberculosis
    K03990  C3; complement component 3
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K03990  C3; complement component 3
   05142 Chagas disease
    K03990  C3; complement component 3
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03990  C3; complement component 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03990  C3; complement component 3
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03990  C3; complement component 3
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03990  C3; complement component 3
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   K03990  C3; complement component 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Opsonins
    K03990  C3; complement component 3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   K03990  C3; complement component 3
Genes
HSA: 718(C3)
PTR: 455644(C3)
PPS: 100982432(C3)
GGO: 101139062(C3)
PON: 100446798(C3)
NLE: 100598784(C3)
MCC: 703613(C3)
MCF: 102131458(C3)
CSAB: 103234342(C3)
RRO: 104665361(C3)
RBB: 108534593(C3)
CJC: 100400501(C3)
SBQ: 101044671(C3)
MMU: 12266(C3)
MCAL: 110312494(C3)
MPAH: 110335652(C3)
RNO: 24232(C3)
MUN: 110545607(C3)
CGE: 100763958(C3)
NGI: 103737182(C3)
HGL: 101726247(C3)
CCAN: 109694300(C3) 109698715
TUP: 102487294(C3)
CFA: 476728(C3)
VVP: 112911820(C3)
AML: 100472549(C3)
UMR: 103681871(C3)
UAH: 113242886(C3)
ORO: 101385252(C3)
ELK: 111161841
FCA: 101088468
PPAD: 109261021(C3) 109261022
BTA: 280677(C3)
BOM: 102270836(C3)
BIU: 109561686(C3)
BBUB: 102407588(C3)
CHX: 100860826(C3)
OAS: 101108131
SSC: 397072(C3)
CFR: 102512172(C3)
CDK: 105104550(C3)
BACU: 103011779(C3)
LVE: 103083690(C3)
OOR: 101281425(C3)
DLE: 111166019(C3)
PCAD: 102979432(C3)
EPZ: 103540378(C3)
EAI: 106832730(C3)
MYD: 102754026
MNA: 107525753(C3)
DRO: 112312430(C3)
PALE: 102882350(C3)
RAY: 107511212(C3)
MJV: 108401780(C3)
LAV: 100657489(C3)
TMU: 101350977
MDO: 100020034(C3)
SHR: 100934148(C3)
PCW: 110197414(C3)
GGA: 396370(C3)
MGP: 100551026(C3)
NMEL: 110391242(C3)
ACYG: 106049436(C3)
TGU: 100222821(C3)
GFR: 102043273
FAB: 101805832
PHI: 102102912(C3)
FPG: 101923177(C3)
FCH: 102047045(C3)
CLV: 102087426(C3)
EGZ: 104129973(C3)
NNI: 104014965(C3)
ACUN: 113490564(C3)
PADL: 103916897(C3)
PSS: 102452901(C3)
CMY: 102933485
ACS: 100555124(c3)
PVT: 110090193
PBI: 103048059(C3)
PMUR: 107287994
PMUA: 114587731
GJA: 107125723
NPR: 108794623(C3)
DRE: 30491(c3a.2) 321046(c3a.1) 494039(c3a.6) 565074(c3a.3)
CCAR: 109074247
PHYP: 113537390
AMEX: 103045627
EEE: 113591926
TRU: 101066599(c3)
LCO: 104939795
OLA: 100125801(c3-1)
XMA: 102235663
XCO: 114144597
PRET: 103475608(c3)
CVG: 107082431
NFU: 107391903(c3)
KMR: 108241457
ALIM: 106528528(c3)
AOCE: 111584065(c3)
CSEM: 103383921
POV: 109627599
LCF: 108885437
SDU: 111229209
SLAL: 111665554(c3)
HCQ: 109527282(c3)
BPEC: 110166125
MALB: 109952399(c3)
SFM: 108919697
PKI: 111841378(c3)
LCM: 102353531(C3)
CMK: 103191243(c3)
RTP: 109916785
CIN: 445694(c3-1)
SPU: 373284(c3)
 » show all
Reference
PMID:2579379
  Authors
de Bruijn MH, Fey GH
  Title
Human complement component C3: cDNA coding sequence and derived primary structure.
  Journal
Proc Natl Acad Sci U S A 82:708-12 (1985)
DOI:10.1073/pnas.82.3.708
  Sequence
[hsa:718]
Reference
  Authors
Murray I, Kohl J, Cianflone K
  Title
Acylation-stimulating protein (ASP): structure-function determinants of cell surface binding and triacylglycerol synthetic activity.
  Journal
Biochem J 342 ( Pt 1):41-8 (1999)
DOI:10.1042/bj3420041
  Sequence
[hsa:718]
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