KEGG   ORTHOLOGY: K04004
Entry
K04004                      KO                                     

Name
CFH, HF1
Definition
complement factor H
Pathway
ko04610  Complement and coagulation cascades
ko05150  Staphylococcus aureus infection
Disease
H00104  Alternative complement pathway component defects
H00821  Age-related macular degeneration
H00825  Familial flecked retina syndrome
H01434  Atypical hemolytic uremic syndrome
H01726  Membranoproliferative glomerulonephritis
H02108  Basal laminar drusen
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K04004  CFH, HF1; complement factor H
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K04004  CFH, HF1; complement factor H
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04004  CFH, HF1; complement factor H
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K04004  CFH, HF1; complement factor H
Genes
HSA: 3075(CFH)
PTR: 457601(CFH)
PPS: 100971143(CFH)
GGO: 101130313(CFH)
PON: 100451270(CFH)
NLE: 100600041(CFH)
MCC: 717346(CFH)
MCF: 102133702(CFH)
CSAB: 103230382(CFH)
RBB: 108531415(CFH)
CJC: 100399888(CFH)
SBQ: 101044777
MMU: 12628(Cfh)
MCAL: 110288786
MPAH: 110322014(Cfh)
RNO: 155012(Cfh)
MUN: 110564827
CGE: 100765974
NGI: 103732853(Cfh)
HGL: 101715308(Cfh)
CCAN: 109689621
OCU: 100340175(CFH)
TUP: 102495620(CFH)
CFA: 478952(CFH)
VVP: 112914361(CFH)
AML: 100465619(CFH)
UMR: 103671020(CFH)
UAH: 113242459(CFH)
ORO: 101373866
ELK: 111150965
PTG: 102956603
PPAD: 109261391
BTA: 100336868 280816(CFH)
BOM: 102282186
BIU: 109570520
CHX: 102188881(CFH)
OAS: 106990096
SSC: 397525(CFH)
CFR: 102507941(CFH)
CDK: 105100422(CFH)
BACU: 102999306
LVE: 103085808
OOR: 101271984(CFH)
DLE: 111177442(CFH)
PCAD: 102991067
EPZ: 103554612(CFH)
EAI: 106823391
MYB: 102246318
MYD: 102763280(CFH)
MNA: 107540245
HAI: 109380456(CFH)
DRO: 112318788(CFH)
RAY: 107520841
MJV: 108399583(CFH)
LAV: 100662384(CFH)
TMU: 101344709
MDO: 100026485
SHR: 100914654
PCW: 110197677
OAA: 100681275(CFH)
GGA: 429057(CFH)
MGP: 100541715(CFH)
CJO: 107317154(CFH)
NMEL: 110402268(CFH)
APLA: 101804106
ACYG: 106041536(CFH)
TGU: 100222992(CFH)
LSR: 110467784(CFH)
SCAN: 103815117(CFH)
GFR: 102036592(CFH)
FAB: 101818719(CFH)
PHI: 102104268(CFH)
PMAJ: 107208428(CFH)
CCAE: 111933189(CFH)
CCW: 104695418(CFH)
ETL: 114055859(CFH)
FPG: 101913888(CFH)
FCH: 102057675(CFH)
CLV: 102096114(CFH)
EGZ: 104127620(CFH)
NNI: 104010470(CFH)
ACUN: 113483120(CFH)
PADL: 103918784(CFH)
AAM: 106499662(CFH)
ASN: 102374805
AMJ: 102564273(CFH)
CPIC: 101939299(CFH)
ACS: 100564874
PMUR: 107298667
PMUA: 114598424(CFH)
XLA: 398768
XTR: 394826(cfh)
DRE: 553297(cfh)
SRX: 107741545
SGH: 107560699
CCAR: 109057354
IPU: 108270757
PHYP: 113527029
AMEX: 103046808
EEE: 113582398
TRU: 101077514
LCO: 104936281(cfh)
NCC: 104967508
MZE: 105941283
ONL: 100710693
XMA: 102218360(cfh)
XCO: 114150908
PRET: 103463360
CVG: 107096975
NFU: 107393014
KMR: 108243580(cfh)
ALIM: 106535782
AOCE: 111575812
CSEM: 103399822(cfh)
POV: 109640738
LCF: 108879552
SDU: 111227581(cfh)
SLAL: 111671704(cfh)
HCQ: 109524599
BPEC: 110164222
SASA: 106595673
SALP: 111975416
SFM: 108935381
 » show all
Reference
  Authors
Agarwal V, Asmat TM, Luo S, Jensch I, Zipfel PF, Hammerschmidt S
  Title
Complement regulator Factor H mediates a two-step uptake of Streptococcus pneumoniae by human cells.
  Journal
J Biol Chem 285:23486-95 (2010)
DOI:10.1074/jbc.M110.142703
  Sequence
[hsa:3075]
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