KEGG   ORTHOLOGY: K04073
Entry
K04073                      KO                                     

Name
mhpF
Definition
acetaldehyde dehydrogenase [EC:1.2.1.10]
Pathway
ko00360  Phenylalanine metabolism
ko00362  Benzoate degradation
ko00620  Pyruvate metabolism
ko00621  Dioxin degradation
ko00622  Xylene degradation
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Module
M00545  Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K04073  mhpF; acetaldehyde dehydrogenase
   00650 Butanoate metabolism
    K04073  mhpF; acetaldehyde dehydrogenase
  09105 Amino acid metabolism
   00360 Phenylalanine metabolism
    K04073  mhpF; acetaldehyde dehydrogenase
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K04073  mhpF; acetaldehyde dehydrogenase
   00622 Xylene degradation
    K04073  mhpF; acetaldehyde dehydrogenase
   00621 Dioxin degradation
    K04073  mhpF; acetaldehyde dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.10  acetaldehyde dehydrogenase (acetylating)
     K04073  mhpF; acetaldehyde dehydrogenase
Other DBs
RN: R00228 R01172
COG: COG4569
GO: 0008774
Genes
ECO: b0351(mhpF)
ECJ: JW0342(mhpF)
EBW: BWG_0240(mhpF)
ECOK: ECMDS42_0273(mhpF)
ECE: Z0450(mhpF)
ECS: ECs0406
ECF: ECH74115_0426(mhpF)
ETW: ECSP_0415(mhpF)
ELX: CDCO157_0394
EOI: ECO111_0387(mhpF)
EOJ: ECO26_0387(mhpF)
EOH: ECO103_0333(mhpF)
ECOO: ECRM13514_0495(mhpF)
ECOH: ECRM13516_0331(mhpF)
ESL: O3K_19720
ESO: O3O_05575
ESM: O3M_19705
ECK: EC55989_0358(mhpF)
EOK: G2583_0464(mhpF)
ELH: ETEC_0407
ECW: EcE24377A_0375(mhpF)
ENA: ECNA114_0334(mhpF)
ECOS: EC958_0495
ECX: EcHS_A0415(mhpF)
ECM: EcSMS35_0382(mhpF)
ECY: ECSE_0376
ECR: ECIAI1_0352(mhpF)
ECQ: ECED1_0379(mhpF)
EUM: ECUMN_0394(mhpF)
ECT: ECIAI39_0327(mhpF)
EOC: CE10_0319(mhpF)
EBR: ECB_00305(mhpF)
EBL: ECD_00305(mhpF)
EBE: B21_00309(mhpF)
EBD: ECBD_3306
ELO: EC042_0388(mhpF)
ESE: ECSF_0322
EKF: KO11_21825(mhpF)
EDJ: ECDH1ME8569_0338(mhpF)
ELW: ECW_m0429(mhpF)
ELL: WFL_02110(mhpF)
ELP: P12B_c0311(mhpF) P12B_c0369(mhpF)
ECOJ: P423_01845
SSN: SSON_0330(mhpF)
KPN: KPN_02118(mhpF)
KPU: KP1_3213(mhpF)
KPP: A79E_2126
KPR: KPR_2663(mhpF)
KPJ: N559_2172
KPX: PMK1_04482(mhpF)
KPNU: LI86_10790
KPNK: BN49_3223(mhpF)
KVA: Kvar_2157
KPE: KPK_2205(mhpF)
KOX: KOX_22675
KOE: A225_3412
EBT: EBL_c20000(mhpF)
REE: electrica_02139(mhpF)
KAS: KATP_20210(mhpF)
EBF: D782_1986
SPE: Spro_3026
ECA: ECA1428(nahO)
LRI: NCTC12151_03195(mhpF)
PPSE: BN5_3619(xylQ)
PCQ: PcP3B5_23490(dmpF_1) PcP3B5_25710(dmpF_2)
PPX: T1E_4257(amnH) T1E_4273(tobI)
PPUH: B479_25870
PKC: PKB_3257(amnh1) PKB_3605(amnh3)
PSES: PSCI_2057(xylQ)
PSOS: POS17_2262(xylQ)
PSET: THL1_491
PSIL: PMA3_18065
AVN: Avin_08700(xylQ) Avin_15120(mhpF) Avin_42130
AVL: AvCA_08700(xylQ) AvCA_15120(mhpF) AvCA_42130
ACX: Achr_27760(mhpF) Achr_32740(xylQ)
MAD: HP15_1114(mhpF) HP15_4035(mhpF)
CHAE: CH06BL_23610(mhpF)
RSO: RSp0894(dmpF)
RSM: CMR15_mp10878(mhpF)
RSE: F504_4323
REH: H16_A1806(h16_A1806) H16_B0551(mhpF)
RME: Rmet_5208(mhpF)
BPS: BPSS1808(mhpF)
BPM: BURPS1710b_A0891(mhpF)
BPSE: BDL_5208
BPSM: BBQ_4324
BPSU: BBN_5271
BPSD: BBX_4374
BPZ: BP1026B_II1938(mhpF)
BPK: BBK_4538
BPSH: DR55_5931
BPSA: BBU_4206
BPSO: X996_5728
BUT: X994_5291
BTE: BTH_II0569(mhpF)
BTQ: BTQ_3863
BTJ: BTJ_4895
BTZ: BTL_5689
BTD: BTI_5185
BTV: BTHA_4521
BTHE: BTN_5351
BTHM: BTRA_5625
BTHA: DR62_5489
BTHL: BG87_5696
BOK: DM82_6080
BOC: BG90_4585
BVE: AK36_3501
BCJ: BCAM2122
BCEW: DM40_5001
BCEO: I35_6004
BCON: NL30_34155
BLAT: WK25_27485
BSEM: WJ12_26055
BMEC: WJ16_20005
BGU: KS03_3375
BGO: BM43_7071
BUK: MYA_5003
BFN: OI25_256
PPNM: LV28_21845
PPUL: RO07_16235
PSPU: NA29_20925
PAPI: SG18_00065
BAV: BAV0599(bphG)
BHZ: ACR54_00828(mhpF)
PUT: PT7_2461
AFQ: AFA_13955
POL: Bpro_5135
ACK: C380_15910(bphG)
CTES: O987_08270
JAG: GJA_233
DAR: Daro_3239
SHAL: SHALO_2224
ARA: Arad_7256
XAU: Xaut_0937
MSL: Msil_1478
MTUN: MTUNDRAET4_3893(mhpF)
MMED: Mame_00138(mhpF)
PHP: PhaeoP97_04062(bphJ)
PPIC: PhaeoP14_03832(bphJ)
SGI: SGRAN_1421(mhpF2)
SPHU: SPPYR_1438(mhpF)
SPHM: G432_01980
SPHB: EP837_03395(mhpF)
TMO: TMO_b0122
MAGQ: MGMAQ_0650
BCA: BCE_2156
BCX: BCA_2154
BCF: bcf_10210
BCER: BCK_24225
BTL: BALH_1843
BMYC: DJ92_4637
BMD: BMD_3573(mhpF)
BMEG: BG04_462
BKW: BkAM31D_23415(mhpF)
GTN: GTNG_3152(nbaJ)
GGH: GHH_c14830(pheF)
ASOC: CB4_02451
AAC: Aaci_1620
AAD: TC41_0801(mhpF) TC41_1516(mhpF)
BTS: Btus_0968
SIV: SSIL_3691
DHD: Dhaf_1244
PTH: PTH_0482(MhpF)
TMR: Tmar_1780
SAY: TPY_0641(mhpF)
CHY: CHY_1279(mhpF)
MTA: Moth_1776
TOC: Toce_0377
LPIL: LIP_2172
MTU: Rv3535c(hsaG)
MTC: MT3639(mhpF)
MRA: MRA_3574(mhpF)
MTUR: CFBS_3751
MTD: UDA_3535c
MTUB: MT7199_3597(hsaG)
MTUC: J113_24725
MTUE: J114_18905
MTUH: I917_24810
MTUL: TBHG_03475
MTUT: HKBT1_3736
MTUU: HKBT2_3745
MBO: BQ2027_MB3565C(hsag)
MBB: BCG_3599c
MBT: JTY_3600
MBX: BCGT_3401
MAF: MAF_35470
MMIC: RN08_3911
MCQ: BN44_110027(hsaG)
MCV: BN43_90033(hsaG)
MCZ: BN45_100030(hsaG)
MPA: MAP_0532
MAO: MAP4_3335
MAVI: RC58_16540
MAVU: RE97_16575
MAV: MAV_0626
MID: MIP_00990
MYO: OEM_05430
MIR: OCQ_05510
MLP: MLM_0771
MUL: MUL_2436(mhpF) MUL_4096(mhpF_1)
MMI: MMAR_1505(mhpF) MMAR_5022(mhpF_1)
MMAE: MMARE11_14050(mhpF) MMARE11_48320(mhpF_1)
MMM: W7S_02625
MLI: MULP_01623(mhpF) MULP_05274(mhpF_1)
MHAD: B586_04635
MSHG: MSG_04520(mhpF)
MXE: MYXE_06140(mhpF)
MGI: Mflv_1521
MPHL: MPHLCCUG_00566(mhpF)
MVQ: MYVA_5130
MTHN: 4412656_04051(bphJ)
MHAS: MHAS_03728(mhpF_1) MHAS_04022(mhpF_2)
MDU: MDUV_49650(mhpF)
MAUU: NCTC10437_01139(mhpF) NCTC10437_02745(bphJ_1) NCTC10437_05000(bphJ_2)
MMAG: MMAD_42130 MMAD_47990(mhpF)
MMOR: MMOR_12260(mhpF)
MABB: MASS_0595
MCHE: BB28_02995
MSTE: MSTE_00584
MSAL: DSM43276_00543(mhpF)
MJD: JDM601_3680(mhpF_1)
MTER: 4434518_03652(mhpF_1)
MHIB: MHIB_23780(mhpF) MHIB_30700
CDR: CDHC03_1948(mhpF)
CAMG: CAMM_02600
CEE: CENDO_02770(mhpF)
NFR: ERS450000_00750(mhpF) ERS450000_01015(bphJ_1) ERS450000_03771(bphJ_2)
NCY: NOCYR_0494(mhpF)
NSR: NS506_01253(mhpF)
NAD: NCTC11293_01236(bphJ_1) NCTC11293_04252(mhpF) NCTC11293_04414(bphJ_2)
REQ: REQ_42070
RHS: A3Q41_02908(dmpF)
RRT: 4535765_04742(dmpF)
RCR: NCTC10994_02787(dmpF)
GPO: GPOL_c41180(hsaG)
GOR: KTR9_0811(hsaG)
GRU: GCWB2_04120(mhpF1) GCWB2_17415(mhpF2)
GOM: D7316_02538(mhpF_1) D7316_02562(mhpF_2)
TPR: Tpau_3801
SGR: SGR_565
SCB: SCAB_15201 SCAB_2081(bphG)
SALU: DC74_7439
SALL: SAZ_38400
STRM: M444_14910
SLAU: SLA_6902
SLX: SLAV_27400(mhpF)
SGE: DWG14_08256(dmpF)
SRJ: SRO_1325
KSK: KSE_23720
NDK: I601_0558(mhpF_1) I601_3472(mhpF_2)
SRO: Sros_9114
NML: Namu_4082
AMD: AMED_4219(mhpF)
AMN: RAM_21490
AMM: AMES_4169(mhpF)
AMZ: B737_4169(mhpF)
AOI: AORI_3690(mhpF)
AJA: AJAP_20720(hpdG)
AMQ: AMETH_2975(mhpF)
AMYY: YIM_27905(mhpF)
AORI: SD37_18935
PDX: Psed_4178
PAUT: Pdca_38530(mhpF)
KAL: KALB_5137
SAQ: Sare_3901
MIL: ML5_3356
AFS: AFR_23750
RCA: Rcas_2411
CAU: Caur_1350
CAG: Cagg_2033
TRO: trd_1393
TTJ: TTHB247
AG: CAA43226(dmpF)
 » show all
Reference
  Authors
Lee SJ, Ko JH, Kang HY, Lee Y
  Title
Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.
  Journal
Biochem Biophys Res Commun 346:1009-15 (2006)
DOI:10.1016/j.bbrc.2006.06.009
  Sequence
[eco:b0351]
Reference
PMID:22316175 (EC:1.2.1.10 1.2.1.87)
  Authors
Baker P, Hillis C, Carere J, Seah SY
  Title
Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes.
  Journal
Biochemistry 51:1942-52 (2012)
DOI:10.1021/bi201832a
  Sequence
[ttj:TTHB247]
LinkDB

KEGG   ORTHOLOGY: K18366
Entry
K18366                      KO                                     

Name
bphJ, xylQ, nahO, tesF
Definition
acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
Pathway
ko00362  Benzoate degradation
ko00620  Pyruvate metabolism
ko00621  Dioxin degradation
ko00622  Xylene degradation
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00650 Butanoate metabolism
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00622 Xylene degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
   00621 Dioxin degradation
    K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.10  acetaldehyde dehydrogenase (acetylating)
     K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
    1.2.1.87  propanal dehydrogenase (CoA-propanoylating)
     K18366  bphJ, xylQ, nahO, tesF; acetaldehyde/propanal dehydrogenase
Other DBs
RN: R00228 R01172 R09097
COG: COG4569
GO: 0008774
Genes
PATR: EV46_07230
PATO: GZ59_14670(nahO)
PSD: DSC_09370
RGL: CS053_01765
RBD: ALSL_0878 ALSL_1081
VAF: D1115_22445
PRE: PCA10_13830
PPI: ND085(nahO)
PPUT: L483_14060
PPUN: PP4_27270(mhpF)
PPUU: PputUW4_01661(mhpF)
PKC: PKB_4238(nahO)
PSET: THL1_1434
PSIL: PMA3_11730
AVN: Avin_30580(lapF)
AVL: AvCA_30580(lapF)
AVD: AvCA6_30580(lapF)
SPL: Spea_2117
SHL: Shal_2089
SWD: Swoo_1391
PHA: PSHAa2142(mhpF)
PTN: PTRA_a2595(bphJ)
PNG: PNIG_a2789(bphJ)
MARJ: MARI_05450(bphJ)
SALH: HMF8227_02731(bphJ)
CJA: CJA_1528(nahO)
HMAR: HVMH_0575(mhpF)
CYQ: Q91_0509(nahO) Q91_1490
AEH: Mlg_2461
TBN: TBH_C0929
GPB: HDN1F_27080(aphF)
NZO: SAMEA4504057_0443(bphJ)
NCI: NCTC10296_00918(bphJ)
RPI: Rpic_4618
REH: H16_B0596(h16_B0596)
RME: Rmet_1320(mhpF)
CTI: RALTA_B0400(mhpF)
BCJ: BCAM1614(mhpF)
BCEO: I35_5474(mhpF)
BMEC: WJ16_26795
BXE: Bxe_C1188(bphJ)
BXB: DR64_8617
BFN: OI25_4590
CABA: SBC2_49010(bphJ)
RFR: Rfer_0455
PNA: Pnap_4143
AJS: Ajs_0223
VEI: Veis_2782
CTES: O987_07735
HPSE: HPF_01855(bphJ)
LCH: Lcho_3341
AZO: azo1856(lapF) azo1973(mhpF) azo2432(nahO)
AAQI: AAQM_0981(dmpF)
ACIB: ACBT_0260(dmpF)
ACLO: ACLO_a0140(dmpF)
AANA: AANAER_1259(dmpF)
ALK: ALEK_0382(dmpF)
ADZ: ADFLV_2552(dmpF)
AFC: AFAEC_1845(dmpF)
ARC: ABLL_2443
SHZ: shn_33315
CID: P73_1381
SGI: SGRAN_1580(mhpF)
SJP: SJA_C1-11900(mhpF)
SINB: SIDU_08315
SFLA: SPHFLASMR4Y_02367(bphJ)
TXI: TH3_21413
HTL: HPTL_0048
SIV: SSIL_0067
KZO: NCTC404_01742(bphJ)
STED: SPTER_02990(bphJ_1) SPTER_36970(bphJ_2)
SAQ: Sare_4566
CWO: Cwoe_4834
 » show all
Reference
  Authors
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T
  Title
Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.
  Journal
Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005
  Sequence
LinkDB

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