KEGG   ORTHOLOGY: K04126
Entry
K04126                      KO                                     

Name
PCBC
Definition
isopenicillin-N synthase [EC:1.21.3.1]
Pathway
ko00311  Penicillin and cephalosporin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00672  Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K04126  PCBC; isopenicillin-N synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.3  With oxygen as acceptor
    1.21.3.1  isopenicillin-N synthase
     K04126  PCBC; isopenicillin-N synthase
Other DBs
RN: R04872
GO: 0016216
Genes
FCD: 110843583
ANI: AN2622.2
AOR: AO090038000544
AFV: AFLA_009030
PCS: Pc21g21380(ips)
ABE: ARB_02225
TVE: TRV_00552
SCT: SCAT_5683(pcbC)
SCY: SCATT_56830
SCLF: BB341_07795
AMYY: YIM_39180(cefE1)
 » show all
Reference
PMID:7791906
  Authors
Roach PL, Clifton IJ, Fulop V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE
  Title
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
  Journal
Nature 375:700-4 (1995)
DOI:10.1038/375700a0
  Sequence
[ani:AN2622.2]
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