KEGG   ORTHOLOGY: K04127
Entry
K04127                      KO                                     

Name
cefD
Definition
isopenicillin-N epimerase [EC:5.1.1.17]
Pathway
ko00311  Penicillin and cephalosporin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00673  Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K04127  cefD; isopenicillin-N epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.17  isopenicillin-N epimerase
     K04127  cefD; isopenicillin-N epimerase
Other DBs
RN: R04147
GO: 0045439
Genes
XCC: XCC1212(nifS)
XCB: XC_3030
XCA: xcc-b100_3093(cefD)
XCP: XCR_1454
XAX: XACM_1285
XPE: BJD13_10100
XTH: G4Q83_19870
SML: Smlt4409
SMT: Smal_3800
BUJ: BurJV3_3836
SMZ: SMD_3984
VAG: N646_3232
PPR: PBPRB0227(SCRA)
PFL: PFL_4607
PPRO: PPC_4709
PFS: PFLU_4835
PFB: VO64_1690
PMAN: OU5_4921
PSEM: TO66_24020
PSOS: POS17_4674
PANR: A7J50_4605
PSIL: PMA3_23020
SPL: Spea_3648
SHL: Shal_3735
SWD: Swoo_4279
FBL: Fbal_3231
MVS: MVIS_3970
RSO: RSp0696
RSL: RPSI07_mp0854(cefD)
RSN: RSPO_c00320(cefD)
RSY: RSUY_02990(cefD)
CGD: CR3_3821(csdB)
BMA: BMAA0692
BMAL: DM55_4745
BMAE: DM78_3245
BMAQ: DM76_3699
BMAI: DM57_12105
BMAF: DM51_4398
BMAZ: BM44_4735
BMAB: BM45_4997
BPS: BPSS0826
BPM: BURPS1710b_A2417(cefD)
BPL: BURPS1106A_A1140(cefD)
BPSE: BDL_4112
BPSM: BBQ_5312
BPSU: BBN_4284
BPSD: BBX_5952
BPK: BBK_3615
BPSH: DR55_4511
BPSA: BBU_5206
BPSO: X996_4060
BUT: X994_3738
BTD: BTI_5642
BDL: AK34_5097
BUL: BW21_5329
PLG: NCTC10937_01176(cefD)
BUO: BRPE64_BCDS08330(sufS)
AAV: Aave_1124
AAA: Acav_1121
DAC: Daci_5319
RTA: Rta_32020
RGE: RGE_38680
MXA: MXAN_5758(cefD)
CCX: COCOR_06250(cefD)
SUR: STAUR_6423(cefD)
SCL: sce8130
BBT: BBta_3802
BARH: WN72_04450
HBA: Hbal_2708
SPHI: TS85_22675
SSAN: NX02_08215
SSY: SLG_33460
SPHR: BSY17_3059
SHUM: STHU_41780(cefD)
SVC: STVA_45250(nifS)
HTQ: FRZ44_45180(nifS)
HADH: FRZ61_42820(nifS)
BBA: Bd2034
BBAT: Bdt_2002
BBW: BDW_07330
BBAC: EP01_06195
MMAG: MMAD_03810(cefD)
SGB: WQO_32335
SCT: SCAT_5686(cefD)
SBH: SBI_00921
STRM: M444_06915
SRW: TUE45_pSRc_0626(cefD)
SMAL: SMALA_2490
SLAU: SLA_7034
SALJ: SMD11_6247
SLX: SLAV_07070(cefD2)
SFK: KY5_0714
SGE: DWG14_07627(cefD_2)
MOY: CVS54_03345(cefD)
ARM: ART_1339
KFL: Kfla_3594
SRO: Sros_3487
KRA: Krad_0174
AMYY: YIM_39195(cefD)
ALO: CRK55303
MIL: ML5_1645
ASE: ACPL_7270(cefD)
ACTN: L083_6863(cefD)
AFS: AFR_36275
ACTS: ACWT_7140
CAI: Caci_5559
SNA: Snas_2195
BLN: Blon_1377
BLON: BLIJ_1421
BBRE: B12L_0972
BBRV: B689b_1067
BBRC: B7019_1125
BBRN: B2258_1017
BBRD: BBBR_1001
CYA: CYA_0818(cefD)
CYB: CYB_1874(cefD)
LET: O77CONTIG1_02952(cefD_2)
LBO: LBWT_6690
AMR: AM1_6324
MAR: MAE_52910
MPK: VL20_1539
NSH: GXM_02799
CALH: IJ00_06455
RCA: Rcas_3584
CAU: Caur_1659
CAG: Cagg_2502
STI: Sthe_1315
ATM: ANT_18540
MRB: Mrub_1746
RBA: RB7564(cefD)
PSL: Psta_2194
PIR: VN12_10170(cefD)
MFF: MFFC18_08200(cefD)
ROL: CA51_19080(cefD)
LCRE: Pla8534_29080(cefD)
AMUC: Pan181_34570(cefD)
PLM: Plim_1607
PEH: Spb1_24620(cefD)
PLS: VT03_15840(cefD)
FMR: Fuma_05761(cefD)
BVO: Pan97_28140(cefD)
MRI: Mal4_46350(cefD)
SDYN: Mal52_22760(cefD)
PLON: Pla110_41390(cefD)
GES: VT84_18005(cefD)
FTJ: FTUN_5065
IPA: Isop_2866
AGV: OJF2_29370(cefD)
ABAC: LuPra_01101(cefD_1) LuPra_04390(cefD_4) LuPra_06203(cefD_5)
GBA: J421_0094
FSN: GS03_01086(cefD)
AG: AAA26714(cefD)
 » show all
Reference
PMID:1694525
  Authors
Kovacevic S, Tobin MB, Miller JR
  Title
The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus.
  Journal
J Bacteriol 172:3952-8 (1990)
DOI:10.1128/JB.172.7.3952-3958.1990
  Sequence
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