KEGG   ORTHOLOGY: K04145
Entry
K04145                      KO                                     

Name
DRD2
Definition
dopamine receptor D2
Pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04540  Gap junction
ko04728  Dopaminergic synapse
ko05012  Parkinson disease
ko05030  Cocaine addiction
ko05034  Alcoholism
Disease
H01611  Alcohol dependence
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04145  DRD2; dopamine receptor D2
   04024 cAMP signaling pathway
    K04145  DRD2; dopamine receptor D2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04145  DRD2; dopamine receptor D2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04145  DRD2; dopamine receptor D2
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    K04145  DRD2; dopamine receptor D2
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K04145  DRD2; dopamine receptor D2
  09165 Substance dependence
   05030 Cocaine addiction
    K04145  DRD2; dopamine receptor D2
   05034 Alcoholism
    K04145  DRD2; dopamine receptor D2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04145  DRD2; dopamine receptor D2
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Biogenic amine
   Dopamine
    K04145  DRD2; dopamine receptor D2
Other DBs
GO: 0001591
TC: 9.A.14.3.10
Genes
HSA: 1813(DRD2)
PTR: 451553(DRD2)
PPS: 100980993(DRD2)
GGO: 101152577(DRD2)
PON: 100442948(DRD2)
NLE: 100589985(DRD2)
MCC: 694181(DRD2)
MCF: 102120020(DRD2)
CSAB: 103248489(DRD2)
RRO: 104677371(DRD2)
RBB: 108536354(DRD2)
CJC: 100400797(DRD2)
SBQ: 101049546(DRD2)
MMU: 13489(Drd2)
MCAL: 110301511(Drd2)
MPAH: 110327760(Drd2)
RNO: 24318(Drd2)
MUN: 110546462(Drd2)
CGE: 100751925(Drd2)
NGI: 103733868(Drd2)
HGL: 101711462(Drd2)
CCAN: 109684952(Drd2)
OCU: 100347371(DRD2)
TUP: 102497400(DRD2)
CFA: 403701(DRD2)
VVP: 112925994(DRD2)
AML: 100468533(DRD2)
UMR: 103662377(DRD2)
UAH: 113260043(DRD2)
ORO: 101363015(DRD2)
ELK: 111153852
FCA: 101096838(DRD2)
PTG: 102962968(DRD2)
PPAD: 109278635(DRD2)
AJU: 106980600(DRD2)
BTA: 281126(DRD2)
BOM: 102271086(DRD2)
BIU: 109569207(DRD2)
BBUB: 102395376(DRD2)
CHX: 102177355(DRD2)
OAS: 101113525(DRD2)
SSC: 100624857(DRD2)
CFR: 102508088(DRD2)
CDK: 105091720(DRD2)
BACU: 103014709(DRD2)
LVE: 103091269(DRD2)
OOR: 101290465(DRD2)
DLE: 111166890(DRD2)
PCAD: 102984954(DRD2)
ECB: 100062195(DRD2)
EPZ: 103567933(DRD2)
EAI: 106840230(DRD2)
MYB: 102238602(DRD2)
MYD: 102757935(DRD2)
MNA: 107531298(DRD2)
HAI: 109394776(DRD2)
DRO: 112314328(DRD2)
PALE: 102883304(DRD2)
RAY: 107512952(DRD2)
MJV: 108409056(DRD2)
LAV: 100671978(DRD2)
TMU: 101349901
MDO: 100026172(DRD2)
SHR: 100915321(DRD2)
PCW: 110210666(DRD2)
OAA: 100093143(DRD2)
GGA: 428252(DRD2)
MGP: 100303660(DRD2)
CJO: 107324316(DRD2)
NMEL: 110387768(DRD2)
APLA: 101804061(DRD2)
ACYG: 106039846(DRD2)
TGU: 100191007(DRD2)
LSR: 110470406(DRD2)
SCAN: 103822980(DRD2)
GFR: 102041928(DRD2)
FAB: 101806581(DRD2)
PHI: 102106330(DRD2)
PMAJ: 107214290(DRD2)
CCAE: 111939232(DRD2)
CCW: 104692072(DRD2)
ETL: 114056264(DRD2)
FPG: 101910542(DRD2)
FCH: 102056546(DRD2)
CLV: 102092586(DRD2)
EGZ: 104125904(DRD2)
NNI: 104019040(DRD2)
ACUN: 113488555(DRD2)
PADL: 103921539(DRD2)
AAM: 106497735(DRD2)
ASN: 102371569(DRD2)
AMJ: 102571561(DRD2)
PSS: 102446398(DRD2)
CMY: 102945726(DRD2)
CPIC: 101949559(DRD2)
ACS: 100557445(drd2)
PVT: 110078819(DRD2)
PBI: 103056226(DRD2)
PMUR: 107284807(DRD2)
PMUA: 114585861(DRD2)
GJA: 107119232(DRD2)
XLA: 378584(drd2.L) 378597(drd2.S)
XTR: 100493063(drd2)
NPR: 108797500(DRD2)
DRE: 282557(drd2a) 378718(drd2l) 378719(drd2b)
PHYP: 113531666 113532573(drd2) 113541240(drd3)
LCO: 104918022(drd2) 104930279
NCC: 104944291
MZE: 101472921 101485235(drd2)
OLA: 101164579(drd2) 101171193
CSEM: 103378413(drd2) 103380303
SDU: 111228043(drd2) 111235768
HCQ: 109515262 109526441(drd2)
BPEC: 110154116(drd2) 110168223
MALB: 109954718 109960173(drd2)
SASA: 106582624 106612463(drd2)
ELS: 105008517 105011551(drd2)
PKI: 111846250(drd2) 111851381
LCM: 102359370(DRD2) 102361922
CMK: 103188716(drd2)
RTP: 109922220(drd2) 109938748
SKO: 102800462
DME: Dmel_CG33517(Dop2R)
DSE: 6615076
DSI: Dsimw501_GD27412(Dsim_GD27412)
DSR: 110184171
DPE: 6597322
DMN: 108164954
DWI: 6644872
DAZ: 108618372
DHE: 111602821
DVI: 6631380
LCQ: 111677032
AGA: AgaP_AGAP004453(GPRDOP3)
AAG: 5564275
AME: 408995(Dop3)
BIM: 100740284
BTER: 100644210
CCAL: 108625913
OBB: 114873579
SOC: 105194927
MPHA: 105840067
AEC: 105143135
ACEP: 105617319
PBAR: 105428795
VEM: 105565509
HST: 105189379
DQU: 106740953
CFO: 105254705
LHU: 105671766
PGC: 109854225
OBO: 105277610
PCF: 106792695
NVI: 100118577
CSOL: 105359613
MDL: 103578787
TCA: 657486
ATD: 109609377
NVL: 108559373
PRAP: 110991628
API: 100166556
DNX: 107166287
RMD: 113560999
CLEC: 106668960
ZNE: 110839781
DPX: DAPPUDRAFT_56664(Dop-R)
PVM: 113817292
TUT: 107371618
DPTE: 113798639
CSCU: 111634846
CEL: CELE_K09G1.4(dop-2) CELE_T14E8.3(dop-3)
CBR: CBG10841(Cbr-dop-3) CBG19316 CBG19317(Cbr-dop-2)
TSP: Tsp_06111
PDAM: 113672806
SPIS: 111340588
HMG: 100200500
 » show all
Reference
  Authors
Albizu L, Holloway T, Gonzalez-Maeso J, Sealfon SC
  Title
Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors.
  Journal
Neuropharmacology 61:770-7 (2011)
DOI:10.1016/j.neuropharm.2011.05.023
  Sequence
[hsa:1813]
Reference
PMID:2532362
  Authors
Grandy DK, Marchionni MA, Makam H, Stofko RE, Alfano M, Frothingham L, Fischer JB, Burke-Howie KJ, Bunzow JR, Server AC, et al.
  Title
Cloning of the cDNA and gene for a human D2 dopamine receptor.
  Journal
Proc Natl Acad Sci U S A 86:9762-6 (1989)
DOI:10.1073/pnas.86.24.9762
  Sequence
[hsa:1813]
LinkDB

KEGG   ORTHOLOGY: K04277
Entry
K04277                      KO                                     

Name
CNR1
Definition
cannabinoid receptor 1
Pathway
ko04015  Rap1 signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04714  Thermogenesis
ko04723  Retrograde endocannabinoid signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04277  CNR1; cannabinoid receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04277  CNR1; cannabinoid receptor 1
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K04277  CNR1; cannabinoid receptor 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K04277  CNR1; cannabinoid receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04277  CNR1; cannabinoid receptor 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Others
   Cannabinoid
    K04277  CNR1; cannabinoid receptor 1
Other DBs
GO: 0004949
TC: 9.A.14.2.2
Genes
HSA: 1268(CNR1)
PTR: 472066(CNR1)
PPS: 100992795(CNR1)
GGO: 101132794(CNR1)
PON: 100436897(CNR1)
NLE: 100587681(CNR1)
MCC: 574142(CNR1)
MCF: 102127382(CNR1)
CSAB: 103240075(CNR1)
RRO: 104661524(CNR1)
RBB: 108515682(CNR1)
CJC: 100393865(CNR1)
SBQ: 101053389(CNR1)
MMU: 12801(Cnr1)
MCAL: 110293089(Cnr1)
MPAH: 110338745(Cnr1)
RNO: 25248(Cnr1)
MUN: 110547363(Cnr1)
CGE: 100768005(Cnr1)
NGI: 103733077(Cnr1)
HGL: 101697935(Cnr1)
CCAN: 109686468(Cnr1)
OCU: 100339826(CNR1)
TUP: 102476019(CNR1)
CFA: 481913(CNR1)
VVP: 112908382(CNR1)
AML: 100483374(CNR1)
UMR: 103659842(CNR1)
UAH: 113264839(CNR1)
ORO: 101365494(CNR1)
ELK: 111158829
FCA: 493926(CNR1)
PTG: 102958794(CNR1)
PPAD: 109263390(CNR1)
AJU: 106972541(CNR1)
BTA: 100299449(CNR1)
BOM: 102270153(CNR1)
BBUB: 102392858(CNR1)
CHX: 102177799(CNR1)
OAS: 101111639(CNR1)
SSC: 100520160(CNR1)
CFR: 102516765(CNR1)
CDK: 105095542(CNR1)
BACU: 103012771(CNR1)
LVE: 103088810(CNR1)
OOR: 101288787(CNR1)
DLE: 111163633(CNR1)
PCAD: 102992769(CNR1)
ECB: 100065681(CNR1)
EPZ: 103549524(CNR1)
EAI: 106826949(CNR1)
MYB: 102248871(CNR1)
MYD: 102773293(CNR1)
MNA: 107533434(CNR1)
HAI: 109392967(CNR1)
DRO: 112297311(CNR1)
PALE: 102887984(CNR1)
RAY: 107508671(CNR1)
MJV: 108403157(CNR1)
LAV: 100671522(CNR1)
TMU: 101348138
MDO: 100019458(CNR1)
SHR: 100918903(CNR1)
PCW: 110192047(CNR1)
OAA: 100076148(CNR1)
GGA: 428633(CNR1)
MGP: 100541856(CNR1)
CJO: 107311975(CNR1)
NMEL: 110396637(CNR1)
APLA: 101801352(CNR1) 113843136
ACYG: 106035413(CNR1)
TGU: 751607(CNR1)
LSR: 110478795(CNR1)
SCAN: 103819302(CNR1)
GFR: 102040886(CNR1)
FAB: 101810795(CNR1)
PHI: 102104259(CNR1)
PMAJ: 107202377(CNR1)
CCAE: 111925745(CNR1)
CCW: 104692354(CNR1)
ETL: 114063760(CNR1)
FPG: 101919596(CNR1)
FCH: 102046181(CNR1)
CLV: 102092703(CNR1)
EGZ: 104135271(CNR1)
NNI: 104021951(CNR1)
ACUN: 113478408(CNR1)
PADL: 103924560(CNR1)
AAM: 106489628(CNR1)
ASN: 102372885(CNR1)
AMJ: 102567511(CNR1)
PSS: 102453854(CNR1)
CMY: 102935826(CNR1)
CPIC: 101947308(CNR1)
ACS: 100555903(cnr1)
PVT: 110076786(CNR1)
PBI: 103056738(CNR1)
PMUR: 107294949(CNR1)
TSR: 106547555(CNR1)
PMUA: 114593942(CNR1)
GJA: 107120821(CNR1)
XLA: 108716878(cnr1.L) 373759(cnr1.S)
XTR: 100497761(cnr1)
NPR: 108785304(CNR1)
DRE: 404209(cnr1)
SRX: 107731524 107742998(cnr1)
SANH: 107660513 107680305(cnr1)
IPU: 108273966(cnr1)
PHYP: 113528702(cnr1)
AMEX: 103021990(cnr1)
EEE: 113590004(cnr1)
TRU: 101066637 101074068(cnr1)
LCO: 104922181 104936193(cnr1)
NCC: 104945549 104966964(cnr1)
MZE: 101464170 101470806(cnr1)
ONL: 100692983(cnr1) 100696119
OLA: 101162493(cnr1) 101174061
XMA: 102229488 102236584(cnr1)
XCO: 114134693 114158891(cnr1)
PRET: 103457370(cnr1) 103458813
CVG: 107081173(cnr1) 107091318
NFU: 107377730(cnr1) 107392251
KMR: 108233336(cnr1) 108234169
ALIM: 106522003 106525684(cnr1)
AOCE: 111577964 111578346(cnr1)
CSEM: 103378019 103381227(cnr1)
SDU: 111226050 111239924(cnr1)
BPEC: 110155444(cnr1)
MALB: 109955154 109962358(cnr1)
ELS: 105016036 105017859(cnr1)
PKI: 111843016(cnr1) 111857900
LCM: 102361307(CNR1)
CMK: 103186201(cnr1)
RTP: 109911587 109921314(cnr1)
BFO: 118425970
CIN: 445655(ciad70l24)
SKO: 102800799
HMG: 100203366
 » show all
Reference
  Authors
Ryberg E, Vu HK, Larsson N, Groblewski T, Hjorth S, Elebring T, Sjogren S, Greasley PJ
  Title
Identification and characterisation of a novel splice variant of the human CB1 receptor.
  Journal
FEBS Lett 579:259-64 (2005)
DOI:10.1016/j.febslet.2004.11.085
  Sequence
[hsa:1268]
LinkDB

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