KEGG   ORTHOLOGY: K04289
Entry
K04289                      KO                                     

Name
LPAR1, EDG2
Definition
lysophosphatidic acid receptor 1
Pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04540  Gap junction
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04072 Phospholipase D signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04151 PI3K-Akt signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
Other DBs
GO: 0070915
Genes
HSA: 1902(LPAR1)
PTR: 464655(LPAR1)
PPS: 100981266(LPAR1)
GGO: 101144872(LPAR1)
PON: 100458931(LPAR1)
NLE: 100589911(LPAR1)
MCC: 709208(LPAR1)
MCF: 101864894(LPAR1) 102125640
CSAB: 103219021(LPAR1)
RRO: 104664137(LPAR1)
RBB: 108513979
CJC: 100414340(LPAR1)
SBQ: 101035023(LPAR1)
MMU: 14745(Lpar1)
MCAL: 110292580(Lpar1)
MPAH: 110322872(Lpar1)
RNO: 116744(Lpar1)
MUN: 110554214(Lpar1)
CGE: 100757522(Lpar1)
NGI: 103732526(Lpar1)
HGL: 101713333(Lpar1)
CCAN: 109692877(Lpar1)
OCU: 100355169(LPAR1)
TUP: 102503029(LPAR1)
CFA: 474800(LPAR1)
VVP: 112923052(LPAR1)
AML: 100479569(LPAR1)
UMR: 103678568(LPAR1)
UAH: 113260324(LPAR1)
ORO: 101371767(LPAR1)
ELK: 111145805
FCA: 101092556(LPAR1)
PTG: 102968521(LPAR1)
PPAD: 109269980(LPAR1)
AJU: 106971772(LPAR1)
BTA: 281136(LPAR1)
BOM: 102273019(LPAR1)
BIU: 109563336(LPAR1) 109563337
BBUB: 102406108(LPAR1)
CHX: 102189399(LPAR1)
OAS: 443346(LPAR1)
SSC: 100512581(LPAR1)
CFR: 102522277(LPAR1)
CDK: 105096434
BACU: 103015300(LPAR1)
LVE: 103091078(LPAR1)
OOR: 101274338(LPAR1)
DLE: 111177336(LPAR1)
PCAD: 102992144(LPAR1)
ECB: 100053797(LPAR1)
EPZ: 103546686(LPAR1)
EAI: 106826903(LPAR1)
MYB: 102258769(LPAR1)
MYD: 102762844(LPAR1)
MNA: 107537650(LPAR1)
HAI: 109379349(LPAR1)
DRO: 112304468(LPAR1)
PALE: 102891503(LPAR1)
RAY: 107502626(LPAR1)
MJV: 108408598(LPAR1)
LAV: 100668056(LPAR1)
TMU: 101344103
MDO: 100016607(LPAR1) 103103209
SHR: 100928953(LPAR1) 100932534
OAA: 100077696(LPAR1)
GGA: 427339(LPAR1)
MGP: 100541536(LPAR1) 109363681
CJO: 107306591(LPAR1)
NMEL: 110389432(LPAR1) 110407913
APLA: 101796868 101802482(LPAR1)
ACYG: 106043035(LPAR1) 106046837
TGU: 100223722(LPAR1) 115497772
LSR: 110467706 110467746(LPAR1)
SCAN: 103820340 103821825(LPAR1)
GFR: 102032612 102038748(LPAR1)
FAB: 101814928 101819651(LPAR1)
PHI: 102105561 102111782(LPAR1)
PMAJ: 107198333(LPAR1) 107212973
CCAE: 111937972 111941320(LPAR1)
CCW: 104690481(LPAR1) 104690993
ETL: 114069483 114072958(LPAR1)
FPG: 101920309(LPAR1) 106112258
FCH: 102050804 102058846(LPAR1)
CLV: 102084885(LPAR1) 102089623
EGZ: 104121830 104123052(LPAR1)
NNI: 104017012 104019835(LPAR1)
ACUN: 113487191 113490290(LPAR1)
PADL: 103917222 103921055(LPAR1)
AAM: 106494707 106499585(LPAR1)
ASN: 102382491(LPAR1) 112551204
AMJ: 102563758(LPAR1)
PSS: 102445645(LPAR1) 102453320
CMY: 102929826 102935396(LPAR1)
CPIC: 101932155(LPAR1) 101940038
ACS: 100565601(lpar1)
PVT: 110075502 110077739(LPAR1)
PBI: 103053763(LPAR1) 103055321
TSR: 106544059(LPAR1) 106555676
PMUA: 114585716 114587543(LPAR1)
GJA: 107108929 107114523(LPAR1)
XLA: 373591(lpar1.L) 379403(lpar1.S)
XTR: 100124893(lpar1) 116408597
NPR: 108787629(LPAR1)
DRE: 368461(lpar1)
SANH: 107653498(lpar1)
IPU: 108277333(lpar1)
PHYP: 113544013
EEE: 113577615(lpar1)
TRU: 101075588
LCO: 104927704(lpar1)
NCC: 104964645(lpar1)
MZE: 101487294(lpar1)
ONL: 100691976(lpar1)
OLA: 101164735(lpar1)
XMA: 102222146(lpar1)
XCO: 114149710(lpar1)
PRET: 103473989(lpar1)
CVG: 107091062(lpar1)
NFU: 107396668(lpar1)
KMR: 108232758(lpar1)
ALIM: 106513587(lpar1)
AOCE: 111581611(lpar1)
CSEM: 103390307(lpar1) 103399363
POV: 109646242(lpar1)
LCF: 108880309(lpar1)
SDU: 111237500
SLAL: 111655943
HCQ: 109530147(lpar1)
BPEC: 110166379
MALB: 109960839(lpar1)
ELS: 105026669
SFM: 108936306
PKI: 111842175
LCM: 102349282(LPAR1)
CMK: 103187154(lpar1)
RTP: 109929476
CIN: 100182538
ADF: 107357274
 » show all
Reference
PMID:9070858
  Authors
An S, Dickens MA, Bleu T, Hallmark OG, Goetzl EJ
  Title
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
  Journal
Biochem Biophys Res Commun 231:619-22 (1997)
DOI:10.1006/bbrc.1997.6150
  Sequence
[hsa:1902]
LinkDB

KEGG   ORTHOLOGY: K04291
Entry
K04291                      KO                                     

Name
LPAR2, EDG4
Definition
lysophosphatidic acid receptor 2
Pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
   04072 Phospholipase D signaling pathway
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
   04151 PI3K-Akt signaling pathway
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
Other DBs
GO: 0070915
TC: 9.A.14.2.5
Genes
HSA: 9170(LPAR2)
PTR: 455878(LPAR2)
PPS: 100988354(LPAR2)
GGO: 101126528(LPAR2)
PON: 100458628(LPAR2)
NLE: 100587344(LPAR2)
MCC: 719844(LPAR2)
MCF: 102120852(LPAR2)
CSAB: 103234222(LPAR2)
RRO: 104680662(LPAR2)
RBB: 108515641(LPAR2)
CJC: 100391457(LPAR2)
SBQ: 101048307(LPAR2)
MMU: 53978(Lpar2)
MCAL: 110300387(Lpar2)
MPAH: 110336830(Lpar2)
RNO: 498609(Lpar2)
MUN: 110549164(Lpar2)
CGE: 100753903(Lpar2)
NGI: 103726831(Lpar2)
HGL: 101721970(Lpar2)
CCAN: 109687178(Lpar2)
OCU: 100343700(LPAR2)
TUP: 102502351(LPAR2)
CFA: 484802(LPAR2)
VVP: 112912747(LPAR2)
AML: 100483313(LPAR2)
UMR: 103675138(LPAR2)
UAH: 113256760(LPAR2)
ORO: 101363634(LPAR2)
ELK: 111144147
FCA: 101100950(LPAR2)
PTG: 102966758(LPAR2)
PPAD: 109247675(LPAR2)
AJU: 106969061(LPAR2)
BTA: 509748(LPAR2)
BOM: 102268794(LPAR2)
BIU: 109561368(LPAR2)
BBUB: 102411165(LPAR2)
CHX: 102187119(LPAR2)
OAS: 101104572(LPAR2)
SSC: 100038015(LPAR2)
CFR: 102504628(LPAR2)
CDK: 105103737(LPAR2)
BACU: 103016779(LPAR2)
LVE: 103074802(LPAR2)
OOR: 101287741(LPAR2)
DLE: 111166724(LPAR2)
PCAD: 102986483(LPAR2)
ECB: 102147510(LPAR2)
EPZ: 103561322(LPAR2)
EAI: 106825461(LPAR2)
MYB: 102246865(LPAR2)
MYD: 102761006(LPAR2)
MNA: 107535357(LPAR2)
HAI: 109382376(LPAR2)
DRO: 112305257(LPAR2)
PALE: 102891807(LPAR2)
RAY: 107503740(LPAR2)
MJV: 108401369(LPAR2)
LAV: 100674529(LPAR2)
TMU: 101360086
MDO: 100014105(LPAR2)
SHR: 100915220(LPAR2)
PCW: 110214461(LPAR2)
GGA: 426086(LPAR2)
MGP: 100550166(LPAR2)
CJO: 107307021(LPAR2)
NMEL: 110391060(LPAR2)
APLA: 101789658(LPAR2)
ACYG: 106049475(LPAR2)
TGU: 115491626(LPAR2)
LSR: 110479080(LPAR2)
SCAN: 103825056(LPAR2)
GFR: 102032251(LPAR2)
PHI: 102112903(LPAR2)
PMAJ: 107199132(LPAR2)
CCAE: 111945421(LPAR2)
ETL: 114072973(LPAR2)
FPG: 101923045(LPAR2)
FCH: 102058075(LPAR2)
EGZ: 104135290(LPAR2)
NNI: 104013846(LPAR2)
ACUN: 113490929(LPAR2)
PADL: 103920849(LPAR2)
AAM: 106500202(LPAR2)
ASN: 102369379(LPAR2)
AMJ: 102561509(LPAR2)
PSS: 102447107
CMY: 102942984(LPAR2)
CPIC: 101951112(LPAR2)
ACS: 100565184(lpar2)
PVT: 110071644(LPAR2)
PBI: 103067510(LPAR2)
PMUR: 107287233(LPAR2)
TSR: 106539958(LPAR2)
PMUA: 114592871(LPAR2)
GJA: 107124321(LPAR2)
XLA: 108711685(lpar2.L) 447460(lpar2.S)
XTR: 493190(lpar2)
NPR: 108800357(LPAR2)
DRE: 445184(lpar2a) 567956(lpar2b)
IPU: 108257275(lpar2) 108258779(LPAR2)
AMEX: 103027992 103037183(lpar2)
NCC: 104952496(lpar2)
PRET: 103468756(lpar2) 103474898
CVG: 107090067 107093411(lpar2)
NFU: 107378328(lpar2) 107389755
ALIM: 106522697 106529464(lpar2)
HCQ: 109511043(lpar2)
ELS: 105005707 105023381(lpar2)
LCM: 102356779
CMK: 103174454
LAK: 106163074
 » show all
Reference
PMID:9525886
  Authors
An S, Bleu T, Hallmark OG, Goetzl EJ
  Title
Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid.
  Journal
J Biol Chem 273:7906-10 (1998)
DOI:10.1074/jbc.273.14.7906
  Sequence
[hsa:9170]
LinkDB

KEGG   ORTHOLOGY: K04275
Entry
K04275                      KO                                     

Name
LPAR4, GPR23
Definition
lysophosphatidic acid receptor 4
Pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
   04072 Phospholipase D signaling pathway
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
   04151 PI3K-Akt signaling pathway
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
Other DBs
GO: 0070915
TC: 9.A.14.13.9
Genes
HSA: 2846(LPAR4)
PTR: 465729(LPAR4)
PPS: 100989638(LPAR4)
GGO: 101150616(LPAR4)
PON: 100459511(LPAR4)
NLE: 100588179(LPAR4)
MCC: 707170(LPAR4)
MCF: 101864899(LPAR4)
CSAB: 103232244(LPAR4)
RRO: 104654349(LPAR4)
RBB: 108529808(LPAR4)
CJC: 100395819(LPAR4)
SBQ: 101044548(LPAR4)
MMU: 78134(Lpar4)
MCAL: 110287196(Lpar4)
MPAH: 110313491(Lpar4)
RNO: 302378(Lpar4)
MUN: 110541171(Lpar4)
CGE: 100752179(Lpar4)
NGI: 103737817(Lpar4)
OCU: 100344512(LPAR4)
TUP: 102500888(LPAR4)
CFA: 491978(LPAR4)
VVP: 112909196(LPAR4)
AML: 100477865(LPAR4)
UMR: 103675824(LPAR4)
UAH: 113242104(LPAR4)
ORO: 101363180(LPAR4)
ELK: 111160942
FCA: 101087973(LPAR4)
PTG: 102962731(LPAR4)
PPAD: 109260287(LPAR4)
AJU: 106987200(LPAR4)
BTA: 539738(LPAR4)
BOM: 102277938(LPAR4)
BBUB: 102411978(LPAR4)
CHX: 102184511(LPAR4)
OAS: 101118506(LPAR4)
SSC: 100038017(LPAR4)
CFR: 102505523(LPAR4)
CDK: 105090092(LPAR4)
BACU: 103017315
LVE: 103078023(LPAR4)
OOR: 101276625(LPAR4)
DLE: 111178180(LPAR4)
PCAD: 102976773(LPAR4)
ECB: 100071749(LPAR4)
EPZ: 103561874(LPAR4)
EAI: 106827637(LPAR4)
MYB: 102246973(LPAR4)
MYD: 102762209(LPAR4)
MNA: 107537244(LPAR4)
HAI: 109385677(LPAR4)
DRO: 112317954(LPAR4)
PALE: 102881134(LPAR4)
RAY: 107500228(LPAR4)
LAV: 100656506(LPAR4)
TMU: 101346400
MDO: 100020275(LPAR4)
SHR: 100914083(LPAR4)
PCW: 110193052(LPAR4)
OAA: 114812808(LPAR4)
GGA: 422149(LPAR4)
MGP: 100539306(LPAR4)
CJO: 107312621(LPAR4)
NMEL: 110403160(LPAR4)
ACYG: 106042983(LPAR4)
TGU: 100226504(LPAR4)
LSR: 110474370(LPAR4)
SCAN: 103816438(LPAR4)
GFR: 102036590(LPAR4)
FAB: 101818510(LPAR4)
PHI: 102099403(LPAR4)
PMAJ: 107203848(LPAR4)
CCAE: 111928583(LPAR4)
CCW: 104691290(LPAR4)
ETL: 114065169(LPAR4)
FPG: 101916616(LPAR4)
FCH: 102058845(LPAR4)
CLV: 102084800(LPAR4)
EGZ: 104135969(LPAR4)
NNI: 104012845(LPAR4)
ACUN: 113479996(LPAR4)
PADL: 103919177(LPAR4)
AAM: 106482083(LPAR4)
ASN: 102377038(LPAR4)
AMJ: 102566056(LPAR4)
PSS: 102445780(LPAR4)
CMY: 102946452(LPAR4)
CPIC: 101944244(LPAR4)
ACS: 100556160 100562456(lpar4)
PVT: 110086630(LPAR4)
PBI: 103065158(LPAR4) 103067277(HCAR1)
PMUR: 107289964(LPAR4) 107296113
TSR: 106549815(LPAR4) 106553862
PMUA: 114589214(LPAR4) 114599968
GJA: 107121365(LPAR4) 107125005
XLA: 108700165(lpar4.S) 779407(lpar4.L)
XTR: 780308(lpar4)
NPR: 108795346(LPAR4)
DRE: 794698(lpar4)
IPU: 108268431(lpar4)
PHYP: 113542682(lpar4)
AMEX: 103042068
EEE: 113570362 113574177(lpar4)
LCO: 104920594(lpar4)
NCC: 104946178(lpar4)
MZE: 101469114 101482060(lpar4)
XCO: 114139701
NFU: 107375389
KMR: 108237951
ALIM: 106518132(lpar4)
AOCE: 111562742 111569862(lpar4)
CSEM: 103391316(lpar4)
POV: 109630081(lpar4) 109634450
LCF: 108882745(lpar4)
SDU: 111226560(lpar4)
SLAL: 111668872
HCQ: 109524498(lpar4)
BPEC: 110153794(lpar4)
MALB: 109957477(lpar4)
ELS: 105007557(lpar4)
SFM: 108922905 108925231(lpar4)
LCM: 102353655(LPAR4)
CMK: 103176311 103177830(lpar4)
RTP: 109912325(lpar4) 109927492
MYI: 110442869
DGT: 114517624
 » show all
Reference
  Authors
Noguchi K, Ishii S, Shimizu T
  Title
Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family.
  Journal
J Biol Chem 278:25600-6 (2003)
DOI:10.1074/jbc.M302648200
  Sequence
[hsa:2846]
LinkDB

KEGG   ORTHOLOGY: K08390
Entry
K08390                      KO                                     

Name
LPAR5, GPR92
Definition
lysophosphatidic acid receptor 5
Pathway
ko04015  Rap1 signaling pathway
ko04072  Phospholipase D signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
   04072 Phospholipase D signaling pathway
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
   04151 PI3K-Akt signaling pathway
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
Genes
HSA: 57121(LPAR5)
PTR: 747759(LPAR5)
PPS: 100974345(LPAR5)
GGO: 101126364(LPAR5)
PON: 100444153(LPAR5)
NLE: 100586980(LPAR5)
MCC: 713283(LPAR5)
MCF: 102146767(LPAR5)
CSAB: 103218464(LPAR5)
RRO: 104680109(LPAR5)
RBB: 108542054(LPAR5)
CJC: 100413340(LPAR5)
SBQ: 101037682(LPAR5)
MMU: 381810(Lpar5)
MCAL: 110297038(Lpar5)
MPAH: 110317128(Lpar5)
RNO: 500317(Lpar5)
MUN: 110548577(Lpar5)
CGE: 100765885(Lpar5)
NGI: 103727518(Lpar5)
HGL: 101716148(Lpar5)
CCAN: 109682765(Lpar5)
OCU: 100347657(LPAR5)
TUP: 102491630(LPAR5)
CFA: 486724(LPAR5)
VVP: 112917350(LPAR5)
AML: 100477983(LPAR5)
UAH: 113257973(LPAR5)
ORO: 101377363(LPAR5)
ELK: 111159825
FCA: 102899848(LPAR5)
PPAD: 109276125(LPAR5)
AJU: 106965444(LPAR5)
BTA: 507598(LPAR5)
BOM: 102276877(LPAR5)
BIU: 109558930(LPAR5)
BBUB: 102407059(LPAR5)
CHX: 102189196(LPAR5)
OAS: 101109610(LPAR5)
SSC: 102161415(LPAR5)
CFR: 102524474(LPAR5)
CDK: 105098214(LPAR5)
BACU: 103015627(LPAR5)
LVE: 103071546(LPAR5)
OOR: 101281432(LPAR5)
PCAD: 102981443(LPAR5)
ECB: 100147585(LPAR5)
EPZ: 103547006(LPAR5)
EAI: 106847340(LPAR5)
MYB: 102250139(LPAR5)
MYD: 102756094(LPAR5)
MNA: 107544026(LPAR5)
HAI: 109373640(LPAR5)
DRO: 112321636(LPAR5)
PALE: 102892521(LPAR5)
RAY: 107519844(LPAR5)
MJV: 108387620(LPAR5)
LAV: 100674432(LPAR5)
TMU: 101343136
MDO: 100015472(LPAR5)
SHR: 100922143(LPAR5)
PCW: 110213879(LPAR5)
OAA: 114807801(LPAR5)
GGA: 418279(LPAR5)
MGP: 100547557(LPAR5)
CJO: 107318862(LPAR5)
NMEL: 110398598(LPAR5)
APLA: 101804147(LPAR5)
ACYG: 106047848(LPAR5)
TGU: 100229694(LPAR5)
LSR: 110480807(LPAR5)
SCAN: 103827152(LPAR5)
GFR: 102041046(LPAR5)
FAB: 101812796(LPAR5)
PHI: 102113993(LPAR5)
PMAJ: 107212790(LPAR5)
CCAE: 111938362(LPAR5)
CCW: 104687119(LPAR5)
ETL: 114058191(LPAR5)
FPG: 101917980(LPAR5)
FCH: 102057164(LPAR5)
CLV: 102090478(LPAR5)
EGZ: 104126530(LPAR5)
NNI: 104009404(LPAR5)
ACUN: 113486812(LPAR5)
PADL: 103922014(LPAR5)
AAM: 106497200(LPAR5)
ASN: 102383882(LPAR5)
AMJ: 102573900(LPAR5)
PSS: 102456044(LPAR5)
CMY: 102947899(LPAR5)
CPIC: 101935808(LPAR5)
ACS: 100566703(lpar5)
PVT: 110084627(LPAR5)
PBI: 103048306(LPAR5)
PMUR: 107285764(LPAR5)
TSR: 106548359(LPAR5)
PMUA: 114588139(LPAR5)
GJA: 107118407(LPAR5)
XLA: 108696063(lpar5.L) 108697350(lpar5.S)
XTR: 100216171(lpar5)
NPR: 108784390(LPAR5)
OTW: 112260400
LCM: 102346747(LPAR5)
RTP: 109925950(lpar5)
 » show all
Reference
  Authors
Hu J, Oda SK, Shotts K, Donovan EE, Strauch P, Pujanauski LM, Victorino F, Al-Shami A, Fujiwara Y, Tigyi G, Oravecz T, Pelanda R, Torres RM
  Title
Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response.
  Journal
J Immunol 193:85-95 (2014)
DOI:10.4049/jimmunol.1300429
  Sequence
[mmu:381810]
LinkDB

KEGG   ORTHOLOGY: K03914
Entry
K03914                      KO                                     

Name
F2R, PAR1
Definition
coagulation factor II (thrombin) receptor
Pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04610  Complement and coagulation cascades
ko04611  Platelet activation
ko04810  Regulation of actin cytoskeleton
ko05130  Pathogenic Escherichia coli infection
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04020 Calcium signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04072 Phospholipase D signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04024 cAMP signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04151 PI3K-Akt signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04611 Platelet activation
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Peptide
   Thrombin
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
Other DBs
GO: 0015057
Genes
HSA: 2149(F2R)
PTR: 471510(F2R)
PPS: 100986369(F2R)
GGO: 101144448(F2R)
PON: 100447792(F2R)
NLE: 100607663(F2R)
MCC: 707370(F2R)
MCF: 102137130(F2R)
CSAB: 103223358(F2R)
RRO: 104655485(F2R)
RBB: 108513076(F2R)
CJC: 100400356(F2R)
SBQ: 101048036(F2R)
MMU: 14062(F2r)
MCAL: 110308051(F2r)
MPAH: 110328985(F2r)
RNO: 25439(F2r)
MUN: 110551097(F2r)
CGE: 100758351(F2r)
NGI: 103752270(F2r)
HGL: 101708544(F2r)
CCAN: 109701102(F2r)
OCU: 100351711(F2R)
TUP: 102485895(F2R)
CFA: 488942(F2R)
VVP: 112919743(F2R)
AML: 105240499(F2R)
UMR: 103663554(F2R)
UAH: 113255187
ORO: 101364644(F2R)
ELK: 111148319
FCA: 101100861(F2R)
PTG: 102964799(F2R)
PPAD: 109274968(F2R)
BTA: 526585(F2R)
BOM: 102272347(F2R)
BIU: 109564649(F2R)
BBUB: 102407393(F2R)
CHX: 102187491(F2R)
OAS: 101105757(F2R)
SSC: 100521609(F2R)
CFR: 102506154(F2R)
CDK: 105084810(F2R)
BACU: 103006270(F2R)
LVE: 103078013(F2R)
OOR: 101278325(F2R)
DLE: 111185188(F2R)
PCAD: 102983891(F2R)
ECB: 100073278(F2R)
EPZ: 103540011(F2R)
EAI: 106824041(F2R)
MYB: 102249171(F2R)
MYD: 102770826(F2R)
MNA: 107531201(F2R)
HAI: 109381883(F2R)
DRO: 112307510(F2R)
PALE: 102886001(F2R)
RAY: 107501531(F2R)
MJV: 108383641(F2R) 108389995
LAV: 100668995(F2R)
TMU: 101358047
MDO: 100010071(F2R)
SHR: 100934757(F2R)
PCW: 110216589(F2R)
OAA: 114813183(F2R)
GGA: 427212(F2R)
MGP: 100543186(F2R)
CJO: 107306072(F2R)
NMEL: 110390007(F2R)
ACYG: 106042104(F2R)
TGU: 100220661(F2R)
LSR: 110471304(F2R)
SCAN: 103819537(F2R)
GFR: 102045591(F2R)
FAB: 101809495(F2R)
PHI: 102108910(F2R)
PMAJ: 107215843(F2R)
CCAE: 111940635(F2R)
CCW: 104698561(F2R)
ETL: 114057079(F2R)
FPG: 101917626(F2R)
FCH: 102055206(F2R)
CLV: 102096136(F2R)
EGZ: 104124890(F2R)
NNI: 104013343(F2R)
ACUN: 113489757(F2R)
PADL: 103919756(F2R)
AAM: 106489297(F2R) 106496616
ASN: 102371571(F2R)
AMJ: 102559171(F2R)
PSS: 102462418(F2R)
CMY: 102932450(F2R)
CPIC: 101935056(F2R)
ACS: 100566666(f2r) 107982334
PVT: 110084596 110084597(F2R)
PBI: 103063671(F2R) 103064541
XLA: 108707268(f2r.S) 378526(f2r.L)
XTR: 100493325(f2r)
DRE: 100124597(f2r2.1) 100149161 558477(f2r) 794215 794278(si:dkey-163m14.6) 794365(si:dkey-163m14.7) 799082(si:dkey-163m14.2) 799156 799227
IPU: 108255687(f2r)
PHYP: 113537012(f2r)
EEE: 113568043 113580495(f2r)
TRU: 101072420(f2r) 101078307
NCC: 104954982(f2r)
PRET: 103470430(f2r) 103473499
CVG: 107084527(f2r) 107090355
NFU: 107374832 107393891(f2r)
KMR: 108234532(f2r) 108244740
ALIM: 106517457(f2r)
AOCE: 111572634 111576016(f2r)
CSEM: 103389897 103398127(f2r)
POV: 109626040 109638049(f2r)
LCF: 108873765 108878175(f2r)
SDU: 111228371(f2r) 111239586
SLAL: 111660342(f2r) 111666761
HCQ: 109514170(f2r) 109529262
BPEC: 110156751(f2r) 110157418
MALB: 109957034(f2r) 109967793
ELS: 105014292
PKI: 111836076 111849769(f2r)
LCM: 102349897(F2R) 102362466
 » show all
Reference
  Authors
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR
  Title
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin.
  Journal
J Clin Invest 103:879-87 (1999)
DOI:10.1172/JCI6042
  Sequence
[hsa:2149]
LinkDB

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