KEGG   ORTHOLOGY: K04348Help
Entry
K04348                      KO                                     

Name
PPP3C, CNA
Definition
serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04114  Oocyte meiosis
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04370  VEGF signaling pathway
ko04380  Osteoclast differentiation
ko04625  C-type lectin receptor signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko04728  Dopaminergic synapse
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05031  Amphetamine addiction
ko05152  Tuberculosis
ko05163  Human cytomegalovirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Disease
H02150  Infantile or early childhood epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04310 Wnt signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04370 VEGF signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04020 Calcium signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04022 cGMP-PKG signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04218 Cellular senescence
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04650 Natural killer cell mediated cytotoxicity
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04660 T cell receptor signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04658 Th1 and Th2 cell differentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04659 Th17 cell differentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04662 B cell receptor signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04921 Oxytocin signaling pathway
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04924 Renin secretion
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09156 Nervous system
   04724 Glutamatergic synapse
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04728 Dopaminergic synapse
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04720 Long-term potentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09158 Development and regeneration
   04360 Axon guidance
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   04380 Osteoclast differentiation
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05014 Amyotrophic lateral sclerosis (ALS)
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09165 Substance dependence
   05031 Amphetamine addiction
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05170 Human immunodeficiency virus 1 infection
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05163 Human cytomegalovirus infection
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit
BRITE hierarchy
Other DBs
COG: COG0639
GO: 0004723
Genes
HSA: 5530(PPP3CA) 5532(PPP3CB) 5533(PPP3CC)
PTR: 450898(PPP3CB) 461403(PPP3CA) 742406(PPP3CC)
PPS: 100968593(PPP3CB) 100976831(PPP3CC) 100976987(PPP3CA)
GGO: 101132713(PPP3CB) 101144930(PPP3CA) 101146305(PPP3CC)
PON: 100174530(PPP3CA) 100436675(PPP3CB) 100455542(PPP3CC)
NLE: 100583664(PPP3CA) 100598029(PPP3CC) 100607264(PPP3CB)
MCC: 706955(PPP3CB) 708233(PPP3CC) 709773(PPP3CA)
MCF: 101866070(PPP3CB) 101926738(PPP3CC) 102134477(PPP3CA)
CSAB: 103215459(PPP3CC) 103215997(PPP3CB) 103236040(PPP3CA)
RRO: 104663623 104663969(PPP3CC) 104669965(PPP3CB) 104676543(PPP3CA)
RBB: 108515446(PPP3CA) 108516875(PPP3CB) 108540785(PPP3CC) 108542795
CJC: 100386369(PPP3CA) 100386452(PPP3CC) 100387059(PPP3CB)
SBQ: 101032266(PPP3CB) 101035788(PPP3CA) 101045514(PPP3CC)
MMU: 19055(Ppp3ca) 19056(Ppp3cb) 19057(Ppp3cc)
MCAL: 110290686(Ppp3ca) 110309045(Ppp3cb) 110309273(Ppp3cc)
MPAH: 110321008(Ppp3ca) 110325335(Ppp3cb) 110325367(Ppp3cc)
RNO: 171378(Ppp3cc) 24674(Ppp3ca) 24675(Ppp3cb)
MUN: 110551668(Ppp3cc) 110551992(Ppp3cb) 110555973(Ppp3ca) 110561621
CGE: 100751412(Ppp3cc) 100752571 100764987(Ppp3cb)
NGI: 103728037(Ppp3ca) 103736944(Ppp3cb) 103747869(Ppp3cc)
HGL: 101698959(Ppp3ca) 101708178(Ppp3cb) 101719947(Ppp3cc)
CCAN: 109681777(Ppp3cc) 109682626(Ppp3cb) 109688186
OCU: 100009423(PPP3CA) 100009487(PPP3CB) 100356245(PPP3CC)
TUP: 102478627(PPP3CB) 102478870(PPP3CA) 102480885(PPP3CC)
CFA: 403486(PPP3CA) 479248(PPP3CB) 609027(PPP3CC)
VVP: 112908364(PPP3CA) 112924308(PPP3CB) 112926818(PPP3CC)
AML: 100467653(PPP3CA) 100474970(PPP3CB) 100477289(PPP3CC)
UMR: 103667825(PPP3CB) 103673318(PPP3CC) 103677943(PPP3CA)
UAH: 113259177(PPP3CB) 113263105(PPP3CA) 113270001(PPP3CC)
ORO: 101363063(PPP3CA) 101363831(PPP3CB) 101385000(PPP3CC)
FCA: 101086926(PPP3CB) 101093097(PPP3CC) 101097144(PPP3CA)
PTG: 102949359(PPP3CC) 102952632(PPP3CA) 102963447(PPP3CB)
AJU: 106970974(PPP3CB) 106981120(PPP3CC) 106982482(PPP3CA)
BTA: 286852(PPP3CA) 533527(PPP3CC) 790867(PPP3CB)
BOM: 102266749(PPP3CA) 102275863(PPP3CB) 102286752(PPP3CC)
BIU: 109553732(PPP3CB) 109560300(PPP3CA) 109563107(PPP3CC)
BBUB: 102400064(PPP3CA) 102414534(PPP3CB) 102415631(PPP3CC)
PHD: 102316775(PPP3CC) 102317711(PPP3CA) 102329404(PPP3CB)
CHX: 102176770(PPP3CA) 102179767(PPP3CC) 102184033(PPP3CB)
OAS: 101108104(PPP3CB) 101115429(PPP3CC) 101122602(PPP3CA)
SSC: 100158082(PPP3CC) 396603(PPP3CB) 397241(PPP3CA)
CFR: 102505131(PPP3CA) 102513924(PPP3CB) 102515660(PPP3CC)
CDK: 105089593(PPP3CA) 105092463(PPP3CB) 105102643(PPP3CC)
BACU: 102997475(PPP3CA) 103008480(PPP3CC) 103009446(PPP3CB)
LVE: 103070526(PPP3CC) 103088182(PPP3CB) 103090427(PPP3CA)
OOR: 101271019(PPP3CC) 101278517(PPP3CA) 101286888(PPP3CB)
DLE: 111169035(PPP3CC) 111179107(PPP3CA) 111183521(PPP3CB)
PCAD: 102973173(PPP3CC) 102990815(PPP3CB) 102994784(PPP3CA)
ECB: 100057357(PPP3CC) 100067434(PPP3CA) 100072862(PPP3CB)
EPZ: 103549452(PPP3CB) 103552390(PPP3CA) 103552773(PPP3CC)
EAI: 106834431(PPP3CA) 106842388(PPP3CB) 106847712(PPP3CC)
MYB: 102245752(PPP3CA) 102251300(PPP3CB) 102264111(PPP3CC)
MYD: 102753757(PPP3CC) 102754623(PPP3CB) 102755500(PPP3CA)
MNA: 107536108(PPP3CC) 107545505(PPP3CA) 107545813(PPP3CB)
HAI: 109372443(PPP3CB) 109375958(PPP3CC) 109392365(PPP3CA)
RSS: 109436135(PPP3CC) 109454847(PPP3CB) 109461440(PPP3CA)
DRO: 112305248(PPP3CC) 112305449(PPP3CB) 112317863(PPP3CA)
PALE: 102880029(PPP3CA) 102883156(PPP3CB) 102898473(PPP3CC)
RAY: 107509227(PPP3CC) 107516843(PPP3CB) 107517885(PPP3CA)
LAV: 100661626(PPP3CA) 100664832(PPP3CC) 100677352(PPP3CB)
MDO: 100011077(PPP3CB) 100014900(PPP3CA) 100033104(PPP3CC)
SHR: 100915297(PPP3CC) 100917281(PPP3CB) 100918408(PPP3CA)
PCW: 110200396(PPP3CC) 110209680(PPP3CA) 110221443(PPP3CB)
OAA: 100073776(PPP3CB) 100083890(PPP3CA) 100087467(PPP3CC)
GGA: 101748851(PPP3CC) 378890(PPP3CB) 395113(PPP3CA)
MGP: 100543188 100543676(PPP3CB) 100547009(PPP3CA)
CJO: 107307315(PPP3CC) 107313629(PPP3CA) 107313674 107315797(PPP3CB)
NMEL: 110391318 110391319 110397833(PPP3CA) 110400477(PPP3CB)
APLA: 101792272(PPP3CA) 101794308(PPP3CC) 101800684(PPP3CB)
ACYG: 106033242(PPP3CB) 106048115(PPP3CA) 106049204(PPP3CC)
TGU: 100222189(PPP3CB) 100225527(PPP3CC) 100232244(PPP3CA)
LSR: 110471147(PPP3CA) 110479420(PPP3CC) 110480589(PPP3CB) 110482717
SCAN: 103813987(PPP3CB) 103824434(PPP3CC) 103826268(PPP3CA)
GFR: 102037137(PPP3CA) 102037249(PPP3CB) 102039738(PPP3CC)
FAB: 101807808(PPP3CC) 101813689(PPP3CB) 101818111(PPP3CA)
PHI: 102100025(PPP3CC) 102106610(PPP3CB) 102109818(PPP3CA)
PMAJ: 107203186(PPP3CA) 107206630(PPP3CB) 107213934(PPP3CC)
CCAE: 111928326(PPP3CA) 111931085(PPP3CB) 111938823(PPP3CC)
CCW: 104694838(PPP3CC) 104697093(PPP3CA) 104697310(PPP3CB)
ETL: 114058124(PPP3CB) 114062705(PPP3CA) 114070077(PPP3CC)
FPG: 101914455(PPP3CA) 101917506(PPP3CC) 101918536(PPP3CB)
FCH: 102048177(PPP3CB) 102052148(PPP3CC) 102053077(PPP3CA)
CLV: 102086447(PPP3CA) 102088936(PPP3CC) 102096117(PPP3CB)
EGZ: 104122599(PPP3CA) 104127929(PPP3CC) 104129113(PPP3CB)
NNI: 104017979(PPP3CB) 104019551(PPP3CC) 104021326(PPP3CA)
ACUN: 113479547(PPP3CA) 113481752(PPP3CB) 113490863(PPP3CC)
PADL: 103915573(PPP3CB) 103919557(PPP3CA) 103921517(PPP3CC)
AAM: 106492052(PPP3CA) 106498910(PPP3CB) 106499981(PPP3CC)
ASN: 102377124(PPP3CC) 102382032(PPP3CB) 102386011(PPP3CA)
AMJ: 102573328(PPP3CB) 102576061(PPP3CC) 102576759(PPP3CA)
PSS: 102445775(PPP3CC) 102453558(PPP3CB) 102457798(PPP3CA)
CMY: 102929773(PPP3CA) 102931885(PPP3CB) 102941746(PPP3CC)
CPIC: 101933990(PPP3CA) 101940511(PPP3CC) 101940788(PPP3CB)
ACS: 100552158(ppp3cc) 100555622(ppp3ca) 100562089(ppp3cb)
PVT: 110072175(PPP3CC) 110077763(PPP3CB) 110085339(PPP3CA)
PBI: 103052619 103059540(PPP3CA)
PMUR: 107289259(PPP3CC) 107298959(PPP3CA)
GJA: 107105761(PPP3CA) 107113004(PPP3CC)
XLA: 100381102(ppp3cc.L) 108705261 108712283 380507(ppp3ca) 432106(ppp3cb.L) 447196(ppp3ca.L)
XTR: 100037840(ppp3cb) 100037857(ppp3cc) 100144934(ppp3ca)
NPR: 108789057(PPP3CA) 108792819(PPP3CC) 108793505(PPP3CB)
DRE: 550554(ppp3cb) 557926(ppp3cca) 565241(ppp3ccb) 794574(ppp3ca)
CMK: 103177620(ppp3ca) 103185841(ppp3cb) 103186967 103187759(ppp3cc)
CIN: 100185597
SPU: 588695(ppp3ca)
APLC: 110980404
SKO: 100303571(cna1)
DME: Dmel_CG1455(CanA1) Dmel_CG9819(CanA-14F) Dmel_CG9842(Pp2B-14D)
DSI: Dsimw501_GD15742(Dsim_GD15742) Dsimw501_GD21557(Dsim_GD21557) Dsimw501_GD27266(Dsim_GD27266)
AAG: 5571230
AME: 411046
BIM: 100747656
BTER: 100650999
SOC: 105205864
MPHA: 105832504
AEC: 105150512
ACEP: 105625924
PBAR: 105434032
VEM: 105568189
HST: 105181729
DQU: 106744500
CFO: 105248809
LHU: 105671886
PGC: 109860650
OBO: 105281324
PCF: 106791073
BMOR: 692577(Cna)
PRAP: 110992703
HAW: 110369910
TNL: 113506972
PXY: 105384905
API: 100162175
DNX: 107163721
AGS: 114119050
BTAB: 109040504
ZNE: 110827065
FCD: 110856429
TUT: 107359528
CEL: CELE_C02F4.2(tax-6)
CBR: CBG08362(Cbr-tax-6)
BMY: Bm1_31320
TSP: Tsp_08323
PCAN: 112575601
CRG: 105341116
MYI: 110448600
OBI: 106874522
LAK: 106150691
EPA: 110238114
PDAM: 113667539
SPIS: 111337610
HMG: 100205420(ppp3ca)
PXB: 103942823
SCE: YLR433C(CNA1) YML057W(CMP2)
ERC: Ecym_7032
KMX: KLMA_50182(CMP2)
NCS: NCAS_0A02820(NCAS0A02820) NCAS_0J01890(NCAS0J01890)
NDI: NDAI_0J02460(NDAI0J02460)
TPF: TPHA_0B00570(TPHA0B00570)
TBL: TBLA_0E04600(TBLA0E04600) TBLA_0G02130(TBLA0G02130)
TDL: TDEL_0D01050(TDEL0D01050)
KAF: KAFR_0I00480(KAFR0I00480)
CAL: CAALFM_C100730CA(CMP1)
SLB: AWJ20_3807(CMP2)
NCR: NCU03804
NTE: NEUTE1DRAFT76873(NEUTE1DRAFT_76873)
MGR: MGG_07456
SSCK: SPSK_02365
MAW: MAC_08953
MAJ: MAA_08418
BFU: BCIN_02g01540(BccnA)
MBE: MBM_02740
ANI: AN8820.2
ANG: ANI_1_444064(An07g03620)
ABE: ARB_00785
TVE: TRV_07786
PTE: PTT_20364
ZTR: MYCGRDRAFT_100967(CNB-1)
SPO: SPBP4H10.04(ppb1)
CNE: CNJ02230
CNB: CNBJ1250
PPL: POSPLDRAFT_122457(PP2B-1) POSPLDRAFT_20475(PP2B-2)
ABP: AGABI1DRAFT115816(AGABI1DRAFT_115816) AGABI1DRAFT76707(AGABI1DRAFT_76707)
ABV: AGABI2DRAFT194461(AGABI2DRAFT_194461) AGABI2DRAFT77099(AGABI2DRAFT_77099)
WSE: WALSEDRAFT_59605(Cmp1p)
MGL: MGL_3171
DFA: DFA_02232(canA)
EHI: EHI_017600(126.t00023) EHI_048590(107.t00006) EHI_050920(60.t00035) EHI_051020(5.t00022) EHI_069970(393.t00001) EHI_109570 EHI_115710(355.t00003) EHI_118600 EHI_136190(33.t00008) EHI_146350(260.t00008) EHI_151180(2.t00018) EHI_167510(69.t00006) EHI_178030(261.t00011) EHI_199120(87.t00027)
PYO: PY17X_1230900(PY02315)
PCB: PCHAS_122800(PC000719.01.0)
CPV: cgd6_4200
SMIN: v1.2.005815.t2(symbB.v1.2.005815.t2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8392375
  Authors
Muramatsu T, Kincaid RL
  Title
Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha).
  Journal
Biochim Biophys Acta 1178:117-20 (1993)
DOI:10.1016/0167-4889(93)90117-8
  Sequence
[hsa:5530]
LinkDB All DBs

KEGG   ORTHOLOGY: K06268Help
Entry
K06268                      KO                                     

Name
PPP3R, CNB
Definition
serine/threonine-protein phosphatase 2B regulatory subunit
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04114  Oocyte meiosis
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04360  Axon guidance
ko04370  VEGF signaling pathway
ko04380  Osteoclast differentiation
ko04625  C-type lectin receptor signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko04662  B cell receptor signaling pathway
ko04720  Long-term potentiation
ko04724  Glutamatergic synapse
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis (ALS)
ko05031  Amphetamine addiction
ko05152  Tuberculosis
ko05163  Human cytomegalovirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04310 Wnt signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04370 VEGF signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04020 Calcium signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04022 cGMP-PKG signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04218 Cellular senescence
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04650 Natural killer cell mediated cytotoxicity
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04660 T cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04658 Th1 and Th2 cell differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04659 Th17 cell differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04662 B cell receptor signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04921 Oxytocin signaling pathway
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04924 Renin secretion
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09156 Nervous system
   04724 Glutamatergic synapse
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04720 Long-term potentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09158 Development and regeneration
   04360 Axon guidance
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   04380 Osteoclast differentiation
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05014 Amyotrophic lateral sclerosis (ALS)
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09165 Substance dependence
   05031 Amphetamine addiction
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05170 Human immunodeficiency virus 1 infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05163 Human cytomegalovirus infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
   05167 Kaposi sarcoma-associated herpesvirus infection
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
BRITE hierarchy
Other DBs
COG: COG5126
GO: 0004723
Genes
HSA: 5534(PPP3R1) 5535(PPP3R2)
PTR: 100613118(PPP3R1) 736325(PPP3R2)
PPS: 100995767(PPP3R2)
GGO: 101144871(PPP3R2)
PON: 100461146(PPP3R2) 103889825(PPP3R1)
NLE: 100593195(PPP3R1) 100600788(PPP3R2)
MCC: 100428682(PPP3R1) 574258(PPP3R2)
MCF: 101866439(PPP3R2) 102137250(PPP3R1)
CSAB: 103219106(PPP3R2) 103220127(PPP3R1)
RRO: 104670806(PPP3R2) 104675975(PPP3R1)
RBB: 108537161(PPP3R2)
CJC: 100388148(PPP3R1) 100392986(PPP3R2)
SBQ: 101039659(PPP3R2) 104650539(PPP3R1)
MMU: 19058(Ppp3r1) 19059(Ppp3r2)
MCAL: 110293037(Ppp3r2) 110304839(Ppp3r1)
MPAH: 110322987(Ppp3r2) 110330477(Ppp3r1)
RNO: 29748(Ppp3r1) 29749(Ppp3r2)
MUN: 110558957(Ppp3r1) 110561325
CGE: 100754314(Ppp3r2) 100773706(Ppp3r1)
NGI: 103734750(Ppp3r1) 103749104(Ppp3r2)
HGL: 101706255(Ppp3r1) 101710684(Ppp3r2)
CCAN: 109693705(Ppp3r1) 109696247(Ppp3r2)
OCU: 100344533(PPP3R2)
TUP: 102474096(PPP3R1) 102478386(PPP3R2)
CFA: 610453(PPP3R2) 612559(PPP3R1)
VVP: 112930770(PPP3R2) 112934379(PPP3R1)
AML: 100467683(PPP3R1) 100474742(PPP3R2)
UMR: 103671340(PPP3R1) 103678534(PPP3R2)
UAH: 113244743(PPP3R1) 113260378(PPP3R2)
ORO: 101368686(PPP3R2) 101386271(PPP3R1)
FCA: 101090344(PPP3R1) 101097765(PPP3R2)
PTG: 102965200(PPP3R1) 102967427(PPP3R2)
AJU: 106967692(PPP3R1) 106972076(PPP3R2)
BTA: 282321(PPP3R1) 617585(PPP3R2)
BOM: 102272271(PPP3R1) 102277736(PPP3R2)
BIU: 109563306(PPP3R2) 109566227(PPP3R1)
BBUB: 102400804(PPP3R2) 102406798(PPP3R1)
PHD: 102325503(PPP3R2) 102332014(PPP3R1)
CHX: 102177339(PPP3R2) 102182602(PPP3R1)
OAS: 101120802(PPP3R2) 114108765(PPP3R1)
SSC: 100625117(PPP3R2) 100627903(PPP3R1)
CFR: 106729683(PPP3R2)
BACU: 103009602(PPP3R2)
LVE: 103068473(PPP3R1) 103078845(PPP3R2)
OOR: 101272877(PPP3R1) 105748080(PPP3R2)
DLE: 111186607(PPP3R1) 111188120(PPP3R2)
PCAD: 112065477(PPP3R2) 112067521(PPP3R1)
ECB: 100061874(PPP3R1) 102148270(PPP3R2)
EPZ: 103548960(PPP3R1) 103552460(PPP3R2)
EAI: 106828340(PPP3R1) 106831788(PPP3R2)
MYB: 102247129(PPP3R2) 102250711(PPP3R1)
MYD: 102760712(PPP3R2) 102774846(PPP3R1)
MNA: 107545969(PPP3R1)
HAI: 109379237(PPP3R1)
DRO: 112297858(PPP3R1) 112304508(PPP3R2)
PALE: 102894471(PPP3R1) 102895490(PPP3R2)
RAY: 107499586(PPP3R2) 107506933(PPP3R1)
LAV: 100668807(PPP3R2) 111751572(PPP3R1)
MDO: 100033302(PPP3R1)
SHR: 100918689(PPP3R1)
PCW: 110207663(PPP3R1)
OAA: 100083665(PPP3R1)
GGA: 378804(PPP3R1)
MGP: 100549150(PPP3R1)
CJO: 107310666(PPP3R1)
NMEL: 110396552(PPP3R1)
APLA: 101791746(PPP3R1)
ACYG: 106044692(PPP3R1)
TGU: 100229058(PPP3R1)
LSR: 110484892(PPP3R1)
SCAN: 103821361(PPP3R1)
GFR: 102034017(PPP3R1)
FAB: 101820532(PPP3R1)
PHI: 102111343(PPP3R1)
PMAJ: 107201468(PPP3R1)
CCAE: 111926640(PPP3R1)
CCW: 104696602(PPP3R1)
ETL: 114054864(PPP3R1)
FPG: 101923629(PPP3R1)
FCH: 102050745(PPP3R1)
CLV: 102095954(PPP3R1)
EGZ: 104129247(PPP3R1)
NNI: 104018925(PPP3R1)
ACUN: 113478143(PPP3R1)
PADL: 103917815(PPP3R1)
AAM: 106495909(PPP3R1)
ASN: 102377091(PPP3R1)
AMJ: 106737480(PPP3R1)
PSS: 102448775(PPP3R1)
ACS: 100561213(ppp3r1)
PVT: 110091682(PPP3R1)
PBI: 107326860(PPP3R1)
GJA: 107114939(PPP3R1)
XLA: 108716580(ppp3r1.L) 399215(ppp3r1.S)
XTR: 395037(ppp3r1)
NPR: 108795656(PPP3R1)
DRE: 447814(ppp3r1b) 564337(ppp3r1a)
IPU: 108258530 108263224(ppp3r1)
PHYP: 113537343 113541892(ppp3r1)
EEE: 113579658 113585612(ppp3r1)
TRU: 101071292 101074110(ppp3r1)
LCO: 104918540 104930901(ppp3r1)
NCC: 104954071(ppp3r1)
MZE: 101465581 101487274(ppp3r1)
OLA: 101161991(ppp3r1) 101168674
XMA: 102218918(ppp3r1)
XCO: 114137969(ppp3r1)
PRET: 103472014 103476469(ppp3r1)
NFU: 107376079(ppp3r1)
KMR: 108247263(ppp3r1)
AOCE: 111570968(ppp3r1)
CSEM: 103386871(ppp3r1)
POV: 109634942(ppp3r1) 109645661
LCF: 108873404(ppp3r1) 108888732
SDU: 111227385(ppp3r1) 111237590
HCQ: 109508548 109526689(ppp3r1)
BPEC: 110157106(ppp3r1) 110173890
MALB: 109961064(ppp3r1)
ELS: 105021516 106024317(ppp3r1)
PKI: 111850760(ppp3r1) 111859769
LCM: 102367157(PPP3R1)
CMK: 103177901(ppp3r1)
DME: Dmel_CG11217(CanB2) Dmel_CG4209(CanB)
DSI: Dsimw501_GD15356(Dsim_GD15356) Dsimw501_GD29162(Dsim_GD29162)
MDE: 101894267
LCQ: 111676949
AAG: 5573370
AME: 551313
BIM: 100749634
BTER: 100650453
SOC: 105201645
MPHA: 105835317
AEC: 105144936
ACEP: 105624663
PBAR: 105422521
HST: 105182789
DQU: 106747742
CFO: 105250886
LHU: 105678532
PGC: 109851930
OBO: 105276504
PCF: 106788783
NVI: 100121135
MDL: 103579881
TCA: 664163
DPA: 109542598
NVL: 108556329
BMOR: 692578(Cnb)
PMAC: 106708445
PRAP: 110991898
HAW: 110369812
TNL: 113496220
PXY: 105380958
API: 100162564
DNX: 107163945
BTAB: 109033461
CLEC: 106673033
ZNE: 110826606
FCD: 110842725
TUT: 107372011
DPTE: 113793164
CEL: CELE_F55C10.1(cnb-1)
CBR: CBG23183(Cbr-cnb-1)
BMY: Bm1_50880
TSP: Tsp_02876
PCAN: 112570556
MYI: 110459429
OBI: 106878873
SHX: MS3_08636
EGL: EGR_02530
HMG: 100213359
AQU: 100640962
ATH: AT1G64480(CBL8) AT3G18430 AT4G01420(CBL5) AT4G16350(CBL6) AT4G17615(CBL1) AT4G26560(CBL7) AT4G26570(CBL3) AT4G33000(CBL10) AT5G24270(SOS3) AT5G47100(CBL9) AT5G55990(CBL2)
LJA: Lj0g3v0205869.1(Lj0g3v0205869.1) Lj1g3v0984330.1(Lj1g3v0984330.1) Lj1g3v0984330.2(Lj1g3v0984330.2) Lj1g3v0984330.3(Lj1g3v0984330.3) Lj2g3v1988900.1(Lj2g3v1988900.1) Lj2g3v3318760.1(Lj2g3v3318760.1) Lj3g3v0044110.1(Lj3g3v0044110.1) Lj3g3v0044110.2(Lj3g3v0044110.2) Lj3g3v2442020.1(Lj3g3v2442020.1) Lj3g3v2442020.2(Lj3g3v2442020.2) Lj3g3v2693160.2(Lj3g3v2693160.2) Lj4g3v0095240.2(Lj4g3v0095240.2) Lj4g3v1202210.1(Lj4g3v1202210.1) Lj4g3v2002950.1(Lj4g3v2002950.1) Lj4g3v3014180.1(Lj4g3v3014180.1) Lj4g3v3014180.2(Lj4g3v3014180.2) Lj5g3v0391490.1(Lj5g3v0391490.1) Lj6g3v0704520.1(Lj6g3v0704520.1) Lj6g3v1707200.1(Lj6g3v1707200.1)
VVI: 100243294(CBL01) 100244675 100246874(CBL04) 100249564(CBL05) 100254259(CBL07) 100254683(CBL08) 100259377(CBL06) 100260894(CBL01) 100262221(CBL03) 100263924 100266945(CBL02) 104878144
DOSA: Os01t0579600-01(Os01g0579600) Os01t0598200-01(Os01g0598200) Os01t0711500-00(Os01g0711500) Os02t0291000-00(Os02g0291000) Os02t0291400-00(Os02g0291400) Os02t0480800-00(Os02g0480800) Os02t0802400-01(Os02g0802400) Os03t0448500-01(Os03g0448500) Os03t0626800-01(Os03g0626800) Os05t0534400-01(Os05g0534400) Os08t0442300-01(Os08g0442300) Os08t0442350-01(Os08g0442350) Os10t0564800-01(Os10g0564800) Os12t0162400-01(Os12g0162400) Os12t0597000-01(Os12g0597000)
ATS: 109732811(LOC109732811) 109733825(LOC109733825) 109739617(LOC109739617) 109740273 109742945(LOC109742945) 109744414(LOC109744414) 109748696(LOC109748696) 109756485(LOC109756485) 109761304(LOC109761304) 109762527(LOC109762527) 109763262(LOC109763262) 109763576(LOC109763576) 109770914(LOC109770914) 109780615(LOC109780615) 109787363(LOC109787363)
SCE: YKL190W(CNB1)
ERC: Ecym_7012
KMX: KLMA_10636(CNB1)
NCS: NCAS_0A02710(NCAS0A02710)
NDI: NDAI_0D04640(NDAI0D04640)
TPF: TPHA_0B01930(TPHA0B01930)
TBL: TBLA_0I03160(TBLA0I03160)
TDL: TDEL_0H01410(TDEL0H01410)
KAF: KAFR_0A05790(KAFR0A05790)
CAL: CAALFM_C505160CA(CNB1)
SLB: AWJ20_4204(CNB1)
NCR: NCU03833(cnb-1)
NTE: NEUTE1DRAFT144368(NEUTE1DRAFT_144368)
MGR: MGG_06933
SSCK: SPSK_05470
TRE: TRIREDRAFT_52130(calb)
MAW: MAC_00460
MAJ: MAA_07344
CMT: CCM_03871
BFU: BCIN_03g05990(Bccnb1)
MBE: MBM_08246
ANI: AN6566.2
ANG: ANI_1_152134(An15g00870)
ABE: ARB_04150
TVE: TRV_03941
PTE: PTT_18349
ZTR: MYCGRDRAFT_68731(CANB)
CNE: CND00260
CNB: CNBD5950
PPL: POSPLDRAFT_109275(CAR1)
ABP: AGABI1DRAFT116228(AGABI1DRAFT_116228)
ABV: AGABI2DRAFT135141(AGABI2DRAFT_135141)
MGL: MGL_1603
DDI: DDB_G0267446(cnbA) DDB_G0285999(cnbB)
DFA: DFA_07623(cnbA)
EHI: EHI_106670(217.t00005)
PYO: PY17X_1319200(PY01623)
PCB: PCHAS_131870(PC001255.02.0)
CPV: cgd1_1370
SMIN: v1.2.028178.t1(symbB.v1.2.028178.t1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2558868
  Authors
Guerini D, Krinks MH, Sikela JM, Hahn WE, Klee CB
  Title
Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.
  Journal
DNA 8:675-82 (1989)
DOI:10.1089/dna.1.1989.8.675
  Sequence
[hsa:5534]
LinkDB All DBs

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