KEGG   ORTHOLOGY: K04352
Entry
K04352                      KO                                     

Name
RASA1, RASGAP
Definition
Ras GTPase-activating protein 1
Pathway
ko04010  MAPK signaling pathway
ko04013  MAPK signaling pathway - fly
ko04014  Ras signaling pathway
ko04360  Axon guidance
Disease
H00532  Parkes Weber syndrome
H02043  Capillary malformation-arteriovenous malformation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
   04013 MAPK signaling pathway - fly
    K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
   04014 Ras signaling pathway
    K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
Domain-containing proteins not elsewhere classified [BR:ko04990]
 Pleckstrin homology (PH) domain-containing proteins
  Other PH domain-containing proteins
   K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
Other DBs
GO: 0005096
Genes
HSA: 5921(RASA1)
PTR: 461762(RASA1)
PPS: 100978056(RASA1)
GGO: 101135999(RASA1)
PON: 100172162(RASA1)
NLE: 100582242(RASA1)
MCC: 694085(RASA1)
MCF: 102130897(RASA1)
CSAB: 103224220(RASA1)
RRO: 104655278(RASA1)
RBB: 108541147(RASA1)
CJC: 100415187(RASA1)
SBQ: 101032122(RASA1)
MMU: 218397(Rasa1)
MCAL: 110308133(Rasa1)
MPAH: 110328850(Rasa1)
RNO: 25676(Rasa1)
MUN: 110564462(Rasa1)
CGE: 100762440(Rasa1)
NGI: 103739115(Rasa1)
HGL: 101713771(Rasa1)
CCAN: 109694624(Rasa1)
OCU: 100343398(RASA1)
TUP: 102503100(RASA1)
CFA: 479158(RASA1)
VVP: 112915578(RASA1)
AML: 100465811(RASA1)
UMR: 103672177(RASA1)
UAH: 113255128(RASA1)
ORO: 101372560(RASA1)
ELK: 111148287
FCA: 101095151(RASA1)
PTG: 102959932(RASA1)
PPAD: 109274891(RASA1)
AJU: 106978599(RASA1)
BTA: 282032(RASA1)
BOM: 102266032(RASA1)
BIU: 109562314(RASA1)
BBUB: 102416344(RASA1)
CHX: 102170782(RASA1)
OAS: 101119216(RASA1)
SSC: 100627579(RASA1)
CFR: 102506564(RASA1)
CDK: 105099632(RASA1)
BACU: 102998210(RASA1)
LVE: 103070068(RASA1)
OOR: 101275044(RASA1)
DLE: 111184598(RASA1)
PCAD: 102991867(RASA1)
ECB: 100073242(RASA1)
EPZ: 103545018(RASA1)
EAI: 106841206(RASA1)
MYB: 102264248(RASA1)
MYD: 102760886(RASA1)
MNA: 107535058(RASA1)
HAI: 109381973(RASA1)
DRO: 112307544(RASA1)
PALE: 102883307(RASA1)
RAY: 107499531(RASA1)
MJV: 108394495(RASA1)
LAV: 100670884(RASA1)
TMU: 101359278
MDO: 100013724(RASA1)
SHR: 100933624(RASA1)
PCW: 110222845(RASA1)
OAA: 100080153(RASA1)
GGA: 427327(RASA1)
MGP: 104915268(RASA1)
CJO: 107306505(RASA1)
NMEL: 110389509(RASA1)
APLA: 101801452(RASA1) 101805096
ACYG: 106048991(RASA1)
TGU: 100226598(RASA1) 116806888
LSR: 110479149(RASA1)
SCAN: 103821051(RASA1) 103824743
GFR: 102035204(RASA1) 102040076
FAB: 101809092(RASA1)
PHI: 102100827(RASA1)
PMAJ: 107215992(RASA1)
CCAE: 111941591(RASA1)
CCW: 104693216(RASA1)
ETL: 114069721 114073765(RASA1)
FPG: 101915808(RASA1)
FCH: 102046190(RASA1)
CLV: 102089229(RASA1)
EGZ: 104128363(RASA1)
NNI: 104011928(RASA1)
ACUN: 113490284(RASA1)
PADL: 103924460(RASA1)
ASN: 102382477(RASA1)
AMJ: 102577063(RASA1)
PSS: 102444162(RASA1)
CMY: 102944043(RASA1)
CPIC: 101950575(RASA1)
ACS: 100556494(rasa1)
PVT: 110073983(RASA1)
PBI: 103062402(RASA1)
PMUR: 107302942(RASA1)
TSR: 106554534(RASA1)
PMUA: 114606766(RASA1)
GJA: 107107221(RASA1)
XLA: 106557444(rasa1.L) 108707239(rasa1.S)
XTR: 100135092(rasa1)
NPR: 108800427(RASA1)
DRE: 100002155(rasa1a) 564822(rasa1b)
IPU: 108255829(rasa1)
PHYP: 113536994(rasa1)
AMEX: 103035872(rasa1)
EEE: 113572895(rasa1)
TRU: 101069465(rasa1)
LCO: 104926811(rasa1)
NCC: 104955190
MZE: 101473967(rasa1)
ONL: 100707127(rasa1)
OLA: 101165895(rasa1)
XMA: 102236247(rasa1)
XCO: 114154589(rasa1)
PRET: 103470445(rasa1)
CVG: 107084547(rasa1)
NFU: 107393876(rasa1)
KMR: 108242834(rasa1)
ALIM: 106537030(rasa1)
AOCE: 111562502(rasa1)
CSEM: 103397270(rasa1)
POV: 109633794(rasa1)
LCF: 108878516(rasa1)
SDU: 111226968(rasa1)
SLAL: 111651557(rasa1)
HCQ: 109520643(rasa1)
BPEC: 110157960(rasa1)
MALB: 109956915(rasa1)
ELS: 105014649(rasa1)
SFM: 108930023 108938639(rasa1)
LCM: 102354006(RASA1)
CMK: 103182667(rasa1)
RTP: 109916106
BFO: 118409651
CIN: 100184835
SPU: 576459
APLC: 110987498
DME: Dmel_CG9209(vap)
DER: 6550515
DSE: 6620727
DSI: Dsimw501_GD24496(Dsim_GD24496)
DAN: 6502898
DSR: 110179538
DPE: 6603322
DMN: 117186414
DWI: 6641204
DAZ: 108619327
DNV: 108656827
DHE: 111605549
DVI: 6634829
MDE: 101901421
LCQ: 111688957
AAG: 5577365
AALB: 109428128
AME: 410811
BIM: 100749421
BTER: 100651514
CCAL: 108623071
OBB: 114871859
SOC: 105193626
MPHA: 105833936
AEC: 105154072
ACEP: 105617957
PBAR: 105428551
VEM: 105558130
HST: 105190570
DQU: 106750797
CFO: 105259347
LHU: 105672244
PGC: 109860610
OBO: 105286183
PCF: 106788257
NVI: 100118819
CSOL: 105366945
MDL: 103572256
TCA: 655394
DPA: 109538426
ATD: 109604552
NVL: 108566465
BMOR: 101743695
BMAN: 114248256
PMAC: 106709970
PRAP: 111003525
HAW: 110384229
TNL: 113503316
API: 100160561
DNX: 107173360
AGS: 114123239
RMD: 113554318
BTAB: 109042476
CLEC: 106672464
ZNE: 110837316
FCD: 110846490
PVM: 113822181
TUT: 107367077
DPTE: 113799481
CSCU: 111631484
PTEP: 107455394
PCAN: 112553896
MYI: 110451183
OBI: 106872485
LAK: 106150987
NVE: 5507620
EPA: 110243074
ADF: 107338731
AMIL: 114963197
PDAM: 113679816
SPIS: 111332953
DGT: 114522587
AQU: 100641281
SPAR: SPRG_20260
 » show all
Reference
PMID:3201259
  Authors
Trahey M, Wong G, Halenbeck R, Rubinfeld B, Martin GA, Ladner M, Long CM, Crosier WJ, Watt K, Koths K, et al.
  Title
Molecular cloning of two types of GAP complementary DNA from human placenta.
  Journal
Science 242:1697-700 (1988)
DOI:10.1126/science.3201259
  Sequence
[hsa:5921]
Reference
  Authors
Pamonsinlapatham P, Hadj-Slimane R, Lepelletier Y, Allain B, Toccafondi M, Garbay C, Raynaud F
  Title
p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling.
  Journal
Biochimie 91:320-8 (2009)
DOI:10.1016/j.biochi.2008.10.010
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