KEGG   ORTHOLOGY: K04371
Entry
K04371                      KO                                     

Name
ERK, MAPK1_3
Definition
mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map01524  Platinum drug resistance
map04010  MAPK signaling pathway
map04011  MAPK signaling pathway - yeast
map04012  ErbB signaling pathway
map04013  MAPK signaling pathway - fly
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04111  Cell cycle - yeast
map04114  Oocyte meiosis
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04214  Apoptosis - fly
map04218  Cellular senescence
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04320  Dorso-ventral axis formation
map04350  TGF-beta signaling pathway
map04360  Axon guidance
map04370  VEGF signaling pathway
map04371  Apelin signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04520  Adherens junction
map04540  Gap junction
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04666  Fc gamma R-mediated phagocytosis
map04668  TNF signaling pathway
map04713  Circadian entrainment
map04720  Long-term potentiation
map04722  Neurotrophin signaling pathway
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04726  Serotonergic synapse
map04730  Long-term depression
map04810  Regulation of actin cytoskeleton
map04910  Insulin signaling pathway
map04912  GnRH signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04921  Oxytocin signaling pathway
map04926  Relaxin signaling pathway
map04928  Parathyroid hormone synthesis, secretion and action
map04929  GnRH secretion
map04930  Type II diabetes mellitus
map04933  AGE-RAGE signaling pathway in diabetic complications
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map05010  Alzheimer disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05034  Alcoholism
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05145  Toxoplasmosis
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05216  Thyroid cancer
map05218  Melanoma
map05219  Bladder cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05417  Lipid and atherosclerosis
Disease
H01738  Noonan syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04013 MAPK signaling pathway - fly
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04011 MAPK signaling pathway - yeast
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04012 ErbB signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04014 Ras signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04015 Rap1 signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04350 TGF-beta signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04370 VEGF signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04371 Apelin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04668 TNF signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04066 HIF-1 signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04068 FoxO signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04072 Phospholipase D signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04071 Sphingolipid signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04024 cAMP signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04022 cGMP-PKG signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04151 PI3K-Akt signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04150 mTOR signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09143 Cell growth and death
   04111 Cell cycle - yeast
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04114 Oocyte meiosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04210 Apoptosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04214 Apoptosis - fly
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04218 Cellular senescence
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04520 Adherens junction
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04540 Gap junction
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04550 Signaling pathways regulating pluripotency of stem cells
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04613 Neutrophil extracellular trap formation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04620 Toll-like receptor signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04621 NOD-like receptor signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04625 C-type lectin receptor signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04650 Natural killer cell mediated cytotoxicity
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04660 T cell receptor signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04658 Th1 and Th2 cell differentiation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04659 Th17 cell differentiation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04657 IL-17 signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04662 B cell receptor signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04664 Fc epsilon RI signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04666 Fc gamma R-mediated phagocytosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04062 Chemokine signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04929 GnRH secretion
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04912 GnRH signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04915 Estrogen signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04914 Progesterone-mediated oocyte maturation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04917 Prolactin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04921 Oxytocin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04926 Relaxin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04935 Growth hormone synthesis, secretion and action
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04919 Thyroid hormone signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04928 Parathyroid hormone synthesis, secretion and action
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04916 Melanogenesis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04270 Vascular smooth muscle contraction
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09156 Nervous system
   04724 Glutamatergic synapse
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04725 Cholinergic synapse
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04726 Serotonergic synapse
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04720 Long-term potentiation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04730 Long-term depression
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04723 Retrograde endocannabinoid signaling
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04722 Neurotrophin signaling pathway
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09158 Development and regeneration
   04320 Dorso-ventral axis formation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04360 Axon guidance
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04380 Osteoclast differentiation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05206 MicroRNAs in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05205 Proteoglycans in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05207 Chemical carcinogenesis - receptor activation
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05208 Chemical carcinogenesis - reactive oxygen species
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05203 Viral carcinogenesis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05230 Central carbon metabolism in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05231 Choline metabolism in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05212 Pancreatic cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05225 Hepatocellular carcinoma
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05226 Gastric cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05214 Glioma
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05216 Thyroid cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05221 Acute myeloid leukemia
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05220 Chronic myeloid leukemia
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05218 Melanoma
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05211 Renal cell carcinoma
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05219 Bladder cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05215 Prostate cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05213 Endometrial cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05224 Breast cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05223 Non-small cell lung cancer
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05170 Human immunodeficiency virus 1 infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05161 Hepatitis B
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05160 Hepatitis C
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05171 Coronavirus disease - COVID-19
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05164 Influenza A
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05163 Human cytomegalovirus infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05165 Human papillomavirus infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05132 Salmonella infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05131 Shigellosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05135 Yersinia infection
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05133 Pertussis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05152 Tuberculosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05140 Leishmaniasis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05142 Chagas disease
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05020 Prion disease
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   05022 Pathways of neurodegeneration - multiple diseases
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09165 Substance dependence
   05034 Alcoholism
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   04934 Cushing syndrome
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   01524 Platinum drug resistance
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
   01522 Endocrine resistance
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3
Other DBs
COG: COG0515
GO: 0004707
Genes
HSA: 5594(MAPK1) 5595(MAPK3)
PTR: 454037(MAPK3) 458680(MAPK1)
PPS: 100979542(MAPK3) 100995567(MAPK1)
GGO: 101135988(MAPK3) 101140164(MAPK1)
PON: 100169740(MAPK1) 100431824(MAPK3)
NLE: 100584480(MAPK3) 100600574(MAPK1)
MCC: 698569(MAPK1) 708938(MAPK3)
MCF: 102116996(MAPK3) 102145011(MAPK1)
CSAB: 103222941(MAPK1) 103230532(MAPK3)
CATY: 105598233(MAPK1) 105598850(MAPK3)
PANU: 101006756(MAPK3) 101012041(MAPK1)
RRO: 104676897(MAPK1) 104681150(MAPK3)
RBB: 108523695(MAPK3) 108536070(MAPK1)
TFN: 117087606(MAPK3) 117096627(MAPK1)
PTEH: 111525729(MAPK3) 111530673(MAPK1) 111533157 111533180
CJC: 100400700(MAPK1) 100404815(MAPK3)
SBQ: 101038546(MAPK3) 101043202(MAPK1)
MMUR: 105870697 105871124(MAPK3) 105877796(MAPK1)
MMU: 26413(Mapk1) 26417(Mapk3)
MCAL: 110297836(Mapk3) 110311382(Mapk1)
MPAH: 110320020(Mapk3) 110329343(Mapk1)
RNO: 116590(Mapk1) 50689(Mapk3)
MCOC: 116073648(Mapk6) 116085641(Mapk1) 116102969(Mapk3)
MUN: 110547978(Mapk3) 110553796(Mapk1)
CGE: 100753149(Mapk3) 100759514(Mapk1)
PLEU: 114682732(Mapk1) 114704332(Mapk3) 114710523
NGI: 103726390(Mapk3) 103741442(Mapk1)
HGL: 101702687(Mapk3) 101706099(Mapk1)
CCAN: 109683259(Mapk3) 109684381(Mapk1)
OCU: 100347345(MAPK1) 100348561(MAPK3)
TUP: 102483057(MAPK3) 102496453(MAPK1)
CFA: 100855877(MAPK3) 477575(MAPK1)
VVP: 112907501(MAPK1) 112929340(MAPK3)
VLG: 121475510(MAPK1) 121486545(MAPK3)
AML: 100470035(MAPK1) 100472388(MAPK3)
UMR: 103657827(MAPK3) 103669286(MAPK1)
UAH: 113247020(MAPK1) 113267646(MAPK3)
ORO: 101372573(MAPK1) 101382213(MAPK3)
MPUF: 101671073(MAPK1) 101679748(MAPK3)
EJU: 114202353(MAPK1) 114214409(MAPK3)
MLX: 117999637(MAPK3) 117999826(MAPK1)
FCA: 101087614(MAPK1) 101087958(MAPK3)
PTG: 102960964(MAPK3) 102964841(MAPK1)
PPAD: 109259699(MAPK1) 109261343(MAPK3)
AJU: 106969232(MAPK3) 106990008(MAPK1)
HHV: 120238830(MAPK1) 120242212(MAPK3)
BTA: 327672(MAPK1) 531391(MAPK3)
BOM: 102272368(MAPK3) 102284931(MAPK1)
BIU: 109570973(MAPK1) 109578667(MAPK3)
BBUB: 102396206(MAPK1) 102403296(MAPK3)
CHX: 102186040(MAPK1) 102188824(MAPK3)
OAS: 101115485(MAPK1) 101123008(MAPK3)
ODA: 120871418(MAPK1) 120876943(MAPK3) 120882996
SSC: 100153927(MAPK1) 445013(MAPK3)
CFR: 102517586(MAPK1) 102521659(MAPK3)
CDK: 105095214(MAPK1) 105102769(MAPK3)
BACU: 102999619(MAPK1) 103002590(MAPK3)
LVE: 103070260(MAPK1) 103075543(MAPK3)
OOR: 101273287(MAPK1) 101289394(MAPK3)
DLE: 111163022(MAPK1) 111182181(MAPK3)
PCAD: 102984305(MAPK1) 102989074(MAPK3)
ECB: 100057701(MAPK1) 100066173(MAPK3)
EPZ: 103547261(MAPK3) 103562408(MAPK1)
EAI: 106845632(MAPK3) 106848262(MAPK1)
MYB: 102245641(MAPK1) 102255250(MAPK3)
MYD: 102769037(MAPK1) 102775211(MAPK3)
MMYO: 118656605(MAPK3) 118678650(MAPK1)
MNA: 107530451(MAPK1) 107541504(MAPK3)
HAI: 109385803(MAPK3) 109394900(MAPK1)
DRO: 112301746(MAPK1) 112304801(MAPK3)
SHON: 119000423(MAPK3) 119001903(MAPK1)
AJM: 119040930(MAPK3) 119059157(MAPK1)
MMF: 118640210(MAPK1) 118642307(MAPK3)
PALE: 102885749(MAPK3) 102895390(MAPK1)
RAY: 107497830(MAPK1) 107515836(MAPK3)
MJV: 108398454(MAPK3) 108400663(MAPK1)
TOD: 119234388(MAPK1) 119241775(MAPK3)
LAV: 100658240(MAPK3) 100665157(MAPK1)
MDO: 100012916(MAPK3) 100028096(MAPK1)
SHR: 100913231(MAPK1) 100934330(MAPK3)
PCW: 110215167(MAPK1) 110221918(MAPK3)
OAA: 100085480(MAPK1) 100086487(MAPK3)
GGA: 373953(MAPK1)
PCOC: 116228725(MAPK1)
MGP: 100543845(MAPK1)
CJO: 107321038(MAPK1)
NMEL: 110406180(MAPK1)
APLA: 101800319(MAPK1)
ACYG: 106031260(MAPK1)
TGU: 100220802(MAPK1)
LSR: 110481332(MAPK1)
SCAN: 103818074(MAPK1)
PMOA: 120509773(MAPK1)
GFR: 102043401(MAPK1)
FAB: 101815088(MAPK1)
PHI: 102102818(MAPK1)
PMAJ: 107211727(MAPK1)
CCAE: 111936534(MAPK1)
CCW: 104688782(MAPK1)
ETL: 114061800(MAPK1)
FPG: 101914611(MAPK1)
FCH: 102048221(MAPK1)
CLV: 102084879(MAPK1)
EGZ: 104127223(MAPK1)
NNI: 104020099(MAPK1)
ACUN: 113486052(MAPK1)
PADL: 103922585(MAPK1)
AAM: 106486864(MAPK1)
ASN: 102375250 102376690(MAPK1)
CPOO: 109312999(MAPK1)
GGN: 109290443(MAPK1)
PSS: 102453948(MAPK1)
CMY: 102932555(MAPK3) 102942218(MAPK1)
CPIC: 101936664(MAPK1) 101937531(MAPK3)
TST: 117887996(MAPK1)
CABI: 116822806(MAPK1)
ACS: 100555877(mapk1) 100566699(mapk3)
PVT: 110081803(MAPK3) 110088651(MAPK1)
PBI: 103052178(MAPK1) 103059169
PGUT: 117666745(MAPK3) 117676368(MAPK1)
PMUA: 114582021(MAPK3) 114586322(MAPK1)
ZVI: 118075832(MAPK1) 118094794(MAPK3)
GJA: 107115252(MAPK1) 107117455(MAPK3)
XLA: 397785(mapk1.L) 398985(mapk1.S)
XTR: 549881(mapk1)
NPR: 108794889(MAPK1)
DRE: 360144(mapk1) 399480(mapk3)
IPU: 108255782(mapk1) 108256206
PHYP: 113528208 113537091(mapk1)
AMEX: 103041389 103047585(mapk1)
EEE: 113585589(mapk1) 113592047
TRU: 101066563 101078496(mapk1)
LCO: 104929510 104932685(mapk1)
ELY: 117253153(mapk1) 117268290(mapk3)
PLEP: 121944320(mapk1) 121956713(mapk3)
SLUC: 116054032(mapk1) 116065226(mapk3)
ECRA: 117944578(mapk1) 117957522(mapk3)
PFLV: 114555749(mapk1) 114569468
GAT: 120827198(mapk3) 120831071(mapk1)
MSAM: 119886325(mapk3) 119891295(mapk1)
CUD: 121509618(mapk1) 121529066(mapk3)
MZE: 101474234 101486997(mapk1)
ONL: 100697722 100701546(mapk1)
OAU: 116314562(mapk3) 116333371(mapk1)
OML: 112136385(mapk1) 112146278(mapk3)
XMA: 102235941(mapk1) 102237032
XCO: 114154145(mapk1) 114160039
XHE: 116729383(mapk1) 116735682
PRET: 103469111 103470721(mapk1)
CVG: 107095925(mapk1) 107101186
CTUL: 119777409 119781702(mapk3)
KMR: 108242980(mapk3) 108244549(mapk1)
LCF: 108881026 108891348(mapk1)
SLAL: 111657703 111660943(mapk1)
XGL: 120782944(mapk3) 120805165(mapk1)
HCQ: 109514865 109526913(mapk1)
MALB: 109951143(mapk1) 109958888
ELS: 105006515(mapk1) 105012809
PKI: 111835825 111857802(mapk1)
LOC: 102683764(mapk1)
LCM: 102354262 102355992(MAPK1)
CMK: 103188576(mapk1)
RTP: 109918415
BFO: 118425949
CIN: 778596(erk1/2)
SCLV: 120342060
SPU: 373525
APLC: 110984844
SKO: 100376998
DME: Dmel_CG12559(rl)
DER: 6543275
DSE: 6620522
DSI: Dsimw501_GD28502(Dsim_GD28502)
DAN: 6496775
DSR: 110182853
DPE: 6603366
DMN: 117189168
DWI: 6652698
DAZ: 108610094
DNV: 108658629
DHE: 111594679
DVI: 6629054
MDE: 101889743
LCQ: 111675135
ACOZ: 120957306
AARA: 120902746
AAG: 5578960
AALB: 109417712
CPII: 120415489
AME: 409523
ACER: 107997332
BIM: 100743744
BTER: 100651240
CCAL: 108622098
OBB: 114873233
MGEN: 117223182
NMEA: 116434895
CGIG: 122398575
SOC: 105201951
MPHA: 105840576
AEC: 105149454
ACEP: 105627106
PBAR: 105424175
VEM: 105562454
HST: 105188452
DQU: 106749090
CFO: 105258670
FEX: 115236103
LHU: 105679971
PGC: 109859229
OBO: 105280970
PCF: 106786258
NVI: 100122312
MDL: 103578018
TCA: 655225
DPA: 109535163
ATD: 109603469
AGB: 108917688
NVL: 108559803
APLN: 108744488
PPYR: 116176439
OTU: 111426930
BMOR: 692466(Erk)
BMAN: 114248880
MSEX: 115442325
BANY: 112043463
PMAC: 106720637
PPOT: 106109111
PXU: 106127184
PRAP: 110996883
ZCE: 119835138
HAW: 110369684
TNL: 113491757
API: 100161230
DNX: 107171308
AGS: 114126775
RMD: 113551251
BTAB: 109031868
DCI: 103513749
CLEC: 106669706
NLU: 111043261
ZNE: 110827503
CSEC: 111866618
HAME: 121878849
DSV: 119446046
RMP: 119173672
VDE: 111252478
VJA: 111273684
TUT: 107360716
DPTE: 113796445
PTEP: 107442143
SDM: 118198159
CEL: CELE_F43C1.2(mpk-1)
CBR: CBG21247(Cbr-mpk-1)
BMY: BM_BM4047(Bma-mpk-1)
TSP: Tsp_01601
PCAN: 112561078
BGT: 106051311
GAE: 121368294
CRG: 105334418
MYI: 110461316
PMAX: 117333566
OBI: 106881135
LAK: 106170183
NVE: 5508961
EPA: 110247086
ATEN: 116289672
ADF: 107335330
AMIL: 114955994
PDAM: 113671903
SPIS: 111342764
ATH: AT1G07880(ATMPK13)
BRP: 103843431
CIT: 102609140
TCC: 18590823
EGR: 104423871
CAM: 101496681
LJA: Lj0g3v0316449.1(Lj0g3v0316449.1) Lj0g3v0316449.2(Lj0g3v0316449.2) Lj6g3v1887730.1(Lj6g3v1887730.1) Lj6g3v1887730.2(Lj6g3v1887730.2)
FVE: 101308652
PMUM: 103322343
PDUL: 117630109
MDM: 103447828
CSV: 101218403
CMO: 103502937
JCU: 105631897
QLO: 115988670
VVI: 100251947
SLY: 100736513(MAPK4)
SOT: 102601363(StMPK4)
ITR: 116005302
EGT: 105949164
CSIN: 114285576
BVG: 104903118
DOSA: Os11t0271100-01(Os11g0271100)
BDI: 100834611
ATS: 109784934
ZMA: 103647817
SITA: 101782379
PHAI: 112884820
DCT: 110100836
ATR: 18440606
MNG: MNEG_5225
SCE: YBL016W(FUS3) YGR040W(KSS1)
KMX: KLMA_20041(FUS3) KLMA_30639(KSS1)
NCS: NCAS_0A02120(NCAS0A02120) NCAS_0B05560(NCAS0B05560)
NDI: NDAI_0B02900(NDAI0B02900) NDAI_0D04050(NDAI0D04050)
TPF: TPHA_0C02880(TPHA0C02880) TPHA_0J00630(TPHA0J00630)
TBL: TBLA_0A08430(TBLA0A08430) TBLA_0A08810(TBLA0A08810)
TDL: TDEL_0B04490(TDEL0B04490) TDEL_0D02650(TDEL0D02650)
KAF: KAFR_0C02840(KAFR0C02840) KAFR_0F03900(KAFR0F03900)
CDU: CD36_31320(CEK2) CD36_45970(CEK1)
SLB: AWJ20_4514(FUS3)
NCR: NCU02393(mak-2)
NTE: NEUTE1DRAFT117829(NEUTE1DRAFT_117829)
SMP: SMAC_03492(putative mak2)
MGR: MGG_09565
SSCK: SPSK_00536
NHE: NECHADRAFT_103967(FUS3)
TRE: TRIREDRAFT_121539(tmk1)
MAW: MAC_00098
MAJ: MAA_04503
CMT: CCM_01235
BFU: BCIN_02g08170(bmp1)
MBE: MBM_03013
ANI: AN3719.2
ANG: ANI_1_1432074(An08g10670)
ABE: ARB_07504
TVE: TRV_07105
PNO: SNOG_03299(AY847792)
PTE: PTT_14847
BSC: COCSADRAFT_24574(CHK1)
ZTR: MYCGRDRAFT_73071(MgFus3)
SPO: SPAC31G5.09c(spk1)
ABP: AGABI1DRAFT115254(AGABI1DRAFT_115254) AGABI1DRAFT86785(AGABI1DRAFT_86785)
ABV: AGABI2DRAFT194216(AGABI2DRAFT_194216) AGABI2DRAFT195979(AGABI2DRAFT_195979)
DFA: DFA_01227(erkA)
EHI: EHI_194420(46.t00053)
PCB: PCHAS_091060(PC001036.02.0)
TAN: TA21080
TPV: TP01_0359
BBO: BBOV_IV005520(23.m06268)
SMIN: v1.2.003637.t1(symbB.v1.2.003637.t1) v1.2.009877.t1(symbB.v1.2.009877.t1) v1.2.014907.t1(symbB.v1.2.014907.t1) v1.2.019916.t1(symbB.v1.2.019916.t1) v1.2.029781.t1(symbB.v1.2.029781.t1) v1.2.033809.t1(symbB.v1.2.033809.t1)
LPAN: LPMP_100450(MPK3) LPMP_191330(MPK4) LPMP_300380(MPK12) LPMP_302860(MPK5) LPMP_331460(MPK11)
 » show all
Reference
PMID:9094309
  Authors
Tedford K, Kim S, Sa D, Stevens K, Tyers M
  Title
Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates.
  Journal
Curr Biol 7:228-38 (1997)
DOI:10.1016/S0960-9822(06)00118-7
Reference
PMID:1540184
  Authors
Owaki H, Makar R, Boulton TG, Cobb MH, Geppert TD
  Title
Extracellular signal-regulated kinases in T cells: characterization of human ERK1 and ERK2 cDNAs.
  Journal
Biochem Biophys Res Commun 182:1416-22 (1992)
DOI:10.1016/0006-291X(92)91891-S
  Sequence
[hsa:5594 5595]
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