KEGG   ORTHOLOGY: K04394
Entry
K04394                      KO                                     

Name
CASP4, CASP11
Definition
caspase 4 [EC:3.4.22.57 3.4.22.64]
Pathway
ko04621  NOD-like receptor signaling pathway
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K04394  CASP4, CASP11; caspase 4
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04394  CASP4, CASP11; caspase 4
   05132 Salmonella infection
    K04394  CASP4, CASP11; caspase 4
   05131 Shigellosis
    K04394  CASP4, CASP11; caspase 4
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K04394  CASP4, CASP11; caspase 4
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.57  caspase-4
     K04394  CASP4, CASP11; caspase 4
    3.4.22.64  caspase-11
     K04394  CASP4, CASP11; caspase 4
Peptidases and inhibitors [BR:ko01002]
 Cysteine peptidases
  Family C14: caspase family
   K04394  CASP4, CASP11; caspase 4
Genes
HSA: 837(CASP4)
PTR: 451518(CASP4)
PPS: 100991353(CASP4)
GGO: 101139012 101139367
PON: 100436933
NLE: 100587427(CASP4)
MCC: 704864(CASP4)
MCF: 102116921(CASP4)
CSAB: 103248367(CASP4)
RRO: 104665269(CASP4)
RBB: 108513171
CJC: 100385257(CASP4)
SBQ: 101048389
MMU: 12363(Casp4)
MCAL: 110301962(Casp4)
MPAH: 110328019(Casp4)
RNO: 114555(Casp4)
NGI: 103743234(Casp4)
HGL: 101700797(Casp4)
CCAN: 109694936
OCU: 100359184(CASP4)
TUP: 102468460 102489894(CASP4)
CFA: 403724(CASP4)
VVP: 112925945
AML: 100464921
UMR: 103662442
UAH: 113260124
ORO: 101382016
ELK: 111153907
FCA: 493961(CASP4)
PTG: 102967742
PPAD: 109258467
AJU: 106976501
BTA: 338039(CASP4)
BOM: 102272500(CASP1)
BIU: 109569831
BBUB: 102394992
CHX: 102191717(CASP1)
OAS: 101117272
SSC: 100522887
CDK: 105100419
BACU: 103012084
LVE: 103078575
OOR: 101290090
DLE: 111167555
PCAD: 102987795
ECB: 100069303(CASP4) 100069322
MYD: 102769995
MNA: 107532382
MJV: 108385984
LAV: 100661933
MDO: 100032600
PRET: 103474727
LCF: 108900839
 » show all
Reference
  Authors
Kamada S, Funahashi Y, Tsujimoto Y
  Title
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases.
  Journal
Cell Death Differ 4:473-8 (1997)
DOI:10.1038/sj.cdd.4400268
Reference
PMID:7797592
  Authors
Munday NA, Vaillancourt JP, Ali A, Casano FJ, Miller DK, Molineaux SM, Yamin TT, Yu VL, Nicholson DW
  Title
Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases.
  Journal
J Biol Chem 270:15870-6 (1995)
DOI:10.1074/jbc.270.26.15870
  Sequence
[hsa:837]
Reference
PMID:9491891
  Authors
Wang S, Miura M, Jung YK, Zhu H, Li E, Yuan J
  Title
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.
  Journal
Cell 92:501-9 (1998)
DOI:10.1016/S0092-8674(00)80943-5
  Sequence
[mmu:12363]
Reference
PMID:8702803
  Authors
Wang S, Miura M, Jung Yk, Zhu H, Gagliardini V, Shi L, Greenberg AH, Yuan J
  Title
Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.
  Journal
J Biol Chem 271:20580-7 (1996)
DOI:10.1074/jbc.271.34.20580
  Sequence
[mmu:12363]
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