KEGG   ORTHOLOGY: K04403Help
Entry
K04403                      KO                                     

Name
MAP3K7IP1, TAB1
Definition
TAK1-binding protein 1
Pathway
ko04010  MAPK signaling pathway
ko04064  NF-kappa B signaling pathway
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04668  TNF signaling pathway
ko05130  Pathogenic Escherichia coli infection
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05145  Toxoplasmosis
ko05161  Hepatitis B
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04064 NF-kappa B signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04668 TNF signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04621 NOD-like receptor signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05135 Yersinia infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05161 Hepatitis B
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05168 Herpes simplex virus 1 infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05169 Epstein-Barr virus infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05140 Leishmaniasis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
BRITE hierarchy
Genes
HSA: 10454(TAB1)
PTR: 458845(TAB1)
PPS: 100985128(TAB1)
GGO: 101138846(TAB1) 101140925
PON: 103888975(TAB1)
NLE: 100587157(TAB1)
MCC: 703409(TAB1)
MCF: 102122493(TAB1)
CSAB: 103223342(TAB1)
RRO: 104682560(TAB1)
RBB: 108520466(TAB1)
CJC: 100398947(TAB1)
SBQ: 101041553(TAB1)
MMU: 66513(Tab1)
MCAL: 110310212(Tab1)
MPAH: 110334874(Tab1)
RNO: 315139(Tab1)
MUN: 110557813(Tab1)
CGE: 100771613(Tab1)
NGI: 103748567(Tab1)
HGL: 101696480(Tab1)
CCAN: 109692995(Tab1)
OCU: 100358246(TAB1)
TUP: 102479566(TAB1)
CFA: 481245(TAB1)
VVP: 112933980(TAB1)
AML: 100484077(TAB1)
UMR: 103676518(TAB1)
UAH: 113241761(TAB1)
ORO: 101369401(TAB1)
FCA: 101083606(TAB1)
PTG: 102950874(TAB1)
AJU: 106981055(TAB1)
BTA: 519958(TAB1)
BOM: 102266863(TAB1)
BIU: 109559827(TAB1)
BBUB: 102395598(TAB1)
PHD: 102315673(TAB1)
CHX: 102185161(TAB1)
OAS: 101122943(TAB1)
SSC: 100153785(TAB1)
CFR: 102508813(TAB1)
CDK: 105091931(TAB1)
BACU: 103016005(TAB1)
LVE: 103084128(TAB1)
OOR: 101282675(TAB1)
DLE: 111186464(TAB1)
PCAD: 102983590(TAB1)
ECB: 100070300(TAB1)
EPZ: 103542619(TAB1)
EAI: 106836857(TAB1)
MYB: 102239405(TAB1)
MYD: 102752149(TAB1)
MNA: 107531263(TAB1)
HAI: 109392251(TAB1)
RSS: 109448798(TAB1)
DRO: 112322023(TAB1)
PALE: 102882572(TAB1)
RAY: 107500809(TAB1)
LAV: 100660911(TAB1)
TMU: 101344618
MDO: 100012432(TAB1)
SHR: 100917609(TAB1)
PCW: 110205796(TAB1)
OAA: 100091969(TAB1)
GGA: 418014(TAB1)
MGP: 100543083(TAB1)
CJO: 107312690(TAB1)
NMEL: 110392579(TAB1)
APLA: 101793675(TAB1)
ACYG: 106035856(TAB1)
TGU: 100223478(TAB1)
LSR: 110483855(TAB1)
SCAN: 103813611(TAB1)
GFR: 102037151(TAB1)
FAB: 101806997(TAB1)
PHI: 102100012(TAB1)
PMAJ: 107204714(TAB1)
CCAE: 111934894(TAB1)
CCW: 104696529(TAB1)
ETL: 114055360(TAB1)
FPG: 101921035(TAB1)
FCH: 102056178(TAB1)
CLV: 102097298(TAB1)
EGZ: 104134239(TAB1)
NNI: 104021621(TAB1)
ACUN: 113487745(TAB1)
PADL: 103915676(TAB1)
AAM: 106488645(TAB1)
ASN: 102378385(TAB1)
AMJ: 102563482(TAB1)
PSS: 102453103(TAB1)
CMY: 102930031(TAB1)
CPIC: 101951442(TAB1)
ACS: 100555014(tab1)
PVT: 110088081(TAB1)
PBI: 103054695(TAB1)
PMUR: 107288135
GJA: 107117159(TAB1)
XLA: 108715765(tab1.S) 398025(tab1.L)
XTR: 549217(tab1)
NPR: 108798164(TAB1)
DRE: 403084(tab1)
SRX: 107737983(tab1)
SANH: 107666659(tab1)
IPU: 108273215(tab1)
PHYP: 113538469(tab1)
AMEX: 103038577(tab1)
EEE: 113579727(tab1)
TRU: 101062734(tab1)
LCO: 104925439(tab1)
MZE: 101484781(tab1)
OLA: 101163057(tab1)
XMA: 102220462(tab1)
XCO: 114144243(tab1)
PRET: 103478828(tab1)
NFU: 107375154(tab1)
KMR: 108232138(tab1)
AOCE: 111577584(syngr1)
CSEM: 103383419(tab1)
POV: 109639281(tab1)
LCF: 108889064(tab1)
SDU: 111235905(tab1)
HCQ: 109511279(tab1)
BPEC: 110157716(tab1)
MALB: 109975048(tab1)
OTW: 112241134(tab1)
SALP: 112072398(tab1)
ELS: 105031193(tab1)
SFM: 108928827(tab1)
PKI: 111835987(tab1)
LCM: 102359833(TAB1)
CMK: 103172117(tab1)
CIN: 100179989
SPU: 100887846
APLC: 110981847
SKO: 100370658
AAG: 5565238
AME: 411720
BIM: 100744752
BTER: 100644347
SOC: 105203018
MPHA: 105837212
AEC: 105146532
ACEP: 105624813
PBAR: 105430083
VEM: 105564137
HST: 105184853
DQU: 106749801
CFO: 105254540
LHU: 105672562
PGC: 109854684
OBO: 105274898
PCF: 106786985
NVI: 100117009
MDL: 103571836
TCA: 658149
DPA: 109545565
NVL: 108563302
BMOR: 100529234(tab1)
PMAC: 106715864
PRAP: 110992156
HAW: 110382611
TNL: 113494824
PXY: 105398817
API: 100164790
DNX: 107169127
AGS: 114130105
BTAB: 109031741
CLEC: 106670466
ZNE: 110839291
FCD: 110858144
DPTE: 113797578
CEL: CELE_C44H4.5(tap-1)
CBR: CBG07558(Cbr-tap-1)
PCAN: 112561607
CRG: 105348086
MYI: 110450561
OBI: 106873708
LAK: 106155643
EPA: 110239969
ADF: 107332669
PDAM: 113679341
SPIS: 111321612
HMG: 100201195
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8638164
  Authors
Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K
  Title
TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction.
  Journal
Science 272:1179-82 (1996)
DOI:10.1126/science.272.5265.1179
  Sequence
[hsa:10454]
LinkDB All DBs

KEGG   ORTHOLOGY: K04404Help
Entry
K04404                      KO                                     

Name
MAP3K7IP2, TAB2
Definition
TAK1-binding protein 2
Pathway
ko04010  MAPK signaling pathway
ko04013  MAPK signaling pathway - fly
ko04064  NF-kappa B signaling pathway
ko04214  Apoptosis - fly
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04657  IL-17 signaling pathway
ko04668  TNF signaling pathway
ko05130  Pathogenic Escherichia coli infection
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05145  Toxoplasmosis
ko05161  Hepatitis B
ko05162  Measles
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
Disease
H02199  Congenital heart defects, multiple type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04013 MAPK signaling pathway - fly
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04064 NF-kappa B signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04668 TNF signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
 09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04624 Toll and Imd signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04621 NOD-like receptor signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   04657 IL-17 signaling pathway
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05135 Yersinia infection
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05162 Measles
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05161 Hepatitis B
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05168 Herpes simplex virus 1 infection
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05169 Epstein-Barr virus infection
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
   05140 Leishmaniasis
    K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
BRITE hierarchy
Genes
HSA: 23118(TAB2)
PTR: 463057(TAB2)
PPS: 100992480(TAB2)
GGO: 101126531(TAB2)
PON: 100174071(TAB2)
NLE: 100597932(TAB2)
MCC: 696875(TAB2)
MCF: 101865975(TAB2)
CSAB: 103240159(TAB2)
RRO: 104676257(TAB2)
RBB: 108536673(TAB2)
CJC: 100414129(TAB2)
SBQ: 101040230(TAB2)
MMU: 68652(Tab2)
MCAL: 110303600(Tab2)
MPAH: 110338176(Tab2)
RNO: 308267(Tab2)
MUN: 110540621(Tab2)
CGE: 100759882(Tab2)
NGI: 103731917(Tab2)
HGL: 101698406(Tab2)
CCAN: 109692528(Tab2)
OCU: 100342249(TAB2)
TUP: 102477062 102478674(TAB2)
CFA: 484028(TAB2)
VVP: 112919509(TAB2)
AML: 100468085(TAB2)
UMR: 103666926(TAB2)
UAH: 113259542(TAB2)
ORO: 101369627(TAB2)
FCA: 101098714(TAB2)
PTG: 102959790(TAB2)
AJU: 106987183(TAB2)
BTA: 540203(TAB2)
BOM: 102278516(TAB2)
BIU: 109564026(TAB2)
BBUB: 102413796(TAB2)
PHD: 102316907(TAB2)
CHX: 102187405(TAB2)
OAS: 101122114(TAB2)
SSC: 100156182(TAB2)
CFR: 102516031(TAB2)
CDK: 105100906(TAB2)
BACU: 102997501(TAB2)
LVE: 103074334(TAB2)
OOR: 101284365(TAB2)
DLE: 111166813(TAB2)
PCAD: 102996495(TAB2)
ECB: 100060433(TAB2)
EPZ: 103548723(TAB2)
EAI: 106837218(TAB2)
MYB: 102248925(TAB2)
MYD: 102770532(TAB2)
MNA: 107545742(TAB2)
HAI: 109380888(TAB2)
RSS: 109455407(TAB2)
DRO: 112297111(TAB2)
PALE: 102898592(TAB2)
RAY: 107518453(TAB2)
LAV: 100656450(TAB2)
TMU: 101355146
MDO: 100026855(TAB2)
SHR: 100930713(TAB2)
PCW: 110208533(TAB2)
OAA: 100074866(TAB2)
GGA: 421622(TAB2)
MGP: 100540789(TAB2)
CJO: 107311553(TAB2)
NMEL: 110395593(TAB2)
APLA: 101790309(TAB2)
ACYG: 106034268(TAB2)
TGU: 100225126(TAB2)
LSR: 110468849(TAB2)
SCAN: 103818533(TAB2)
GFR: 102037601(TAB2)
FAB: 101808905(TAB2)
PHI: 102109164(TAB2)
PMAJ: 107202278(TAB2)
CCAE: 111926823(TAB2)
CCW: 104689165(TAB2)
ETL: 114059183(TAB2)
FPG: 101920039(TAB2)
FCH: 102047715(TAB2)
CLV: 102092362(TAB2)
EGZ: 104133546(TAB2)
NNI: 104013777(TAB2)
ACUN: 113478283(TAB2)
PADL: 103917026(TAB2)
AAM: 106486816(TAB2)
ASN: 102386987(TAB2)
AMJ: 102567745(TAB2)
PSS: 102451479(TAB2)
CMY: 102941166(TAB2)
CPIC: 101945138(TAB2)
ACS: 100553005(tab2)
PVT: 110087432(TAB2)
PMUR: 107287407(TAB2)
GJA: 107114113(TAB2)
XLA: 108716751 108717890(tab2.S)
XTR: 100037849(tab2)
NPR: 108789386(TAB2)
DRE: 494163(tab2)
SANH: 107688309(tab2) 107696859
SGH: 107558968 107568749(tab2)
IPU: 108275278(tab2)
PHYP: 113529084(tab2)
AMEX: 103032786(tab2)
EEE: 113589932(tab2)
TRU: 101069621(tab2)
LCO: 104918319(tab2)
NCC: 104941014(tab2)
MZE: 101482482(tab2)
OLA: 101168511(tab2)
XMA: 102236763(tab2)
XCO: 114158125(tab2)
PRET: 103458018(tab2)
NFU: 107396012(tab2)
KMR: 108246525(tab2)
AOCE: 111578164(tab2)
CSEM: 103380596(tab2)
POV: 109632543(tab2)
LCF: 108899320(tab2)
SDU: 111216386(tab2)
HCQ: 109524845(tab2)
BPEC: 110158440(tab2)
MALB: 109968091(tab2)
ELS: 105017897(tab2)
SFM: 108929403(tab2)
PKI: 111843039(tab2)
LCM: 102364705(TAB2)
CMK: 103179281(tab2)
CIN: 100186829
SPU: 591886
DME: Dmel_CG7417(Tab2)
DER: 6547204
DSI: Dsimw501_GD11443(Dsim_GD11443)
DPE: 6601630
DWI: 6637980
DAZ: 108616418
DNV: 108652884
DHE: 111594609
MDE: 101892773
LCQ: 111676934
AAG: 110678810
AME: 726947
BIM: 100745732
BTER: 100647820
SOC: 105196529
MPHA: 105828457
AEC: 105152974
ACEP: 105627500
PBAR: 105428111
VEM: 105558546
HST: 105185405
DQU: 106745789
CFO: 105256180
LHU: 105671382
PGC: 109853511
OBO: 105283447
PCF: 106784177
NVI: 100678005
MDL: 103573502
TCA: 657352(Tab2)
DPA: 109538280
NVL: 108560383
PMAC: 106721029
PRAP: 110994728
HAW: 110373219
TNL: 113497314
API: 100161584
DNX: 107167923
AGS: 114119917
BTAB: 109042671
ZNE: 110838167
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J, Matsumoto K
  Title
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
  Journal
Mol Cell 5:649-58 (2000)
DOI:10.1016/S1097-2765(00)80244-0
  Sequence
[hsa:23118]
LinkDB All DBs

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