K04452                      KO                                     

DNA damage-inducible transcript 3
ko04010  MAPK signaling pathway
ko04141  Protein processing in endoplasmic reticulum
ko04210  Apoptosis
ko04932  Non-alcoholic fatty liver disease
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05202  Transcriptional misregulation in cancer
H00049  Myxoid liposarcoma
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
   05012 Parkinson disease
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
   05014 Amyotrophic lateral sclerosis
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
   05020 Prion disease
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
   05022 Pathways of neurodegeneration - multiple diseases
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   C/EBP-like factors
    K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
HSA: 1649(DDIT3)
PTR: 452017(DDIT3)
PPS: 100982590(DDIT3)
GGO: 101140706(DDIT3)
PON: 100439399(DDIT3)
NLE: 100600067(DDIT3)
MCC: 714901(DDIT3)
MCF: 102131632(DDIT3)
CSAB: 103238566(DDIT3)
RRO: 104682361(DDIT3)
RBB: 108519685(DDIT3)
CJC: 100385367(DDIT3) 103794361
SBQ: 104651132(DDIT3)
MMU: 13198(Ddit3)
MCAL: 110302857(Ddit3)
MPAH: 110326609(Ddit3)
RNO: 29467(Ddit3)
MUN: 110561450(Ddit3)
CGE: 100763514(Ddit3)
NGI: 103742913(Ddit3)
HGL: 101715873(Ddit3)
CCAN: 109675714 109686362(Ddit3)
OCU: 100338439(DDIT3)
TUP: 102500216(DDIT3)
CFA: 607439(DDIT3)
VVP: 112922347(DDIT3)
AML: 100479063(DDIT3)
UMR: 103656598(DDIT3)
UAH: 113256381(DDIT3)
ORO: 101380889(DDIT3)
ELK: 111160240
FCA: 101081819(DDIT3)
PTG: 102965918(DDIT3)
PPAD: 109270377(DDIT3)
AJU: 106975861(DDIT3)
BTA: 777788(DDIT3)
BOM: 102284065(DDIT3)
BIU: 109559326(DDIT3)
BBUB: 102405069(DDIT3)
CHX: 102175557(DDIT3)
OAS: 541600(DDIT3)
SSC: 100240743(DDIT3)
CFR: 102517621(DDIT3)
CDK: 105100346(DDIT3)
BACU: 103018481(DDIT3)
LVE: 103069139(DDIT3)
OOR: 101278090(DDIT3)
DLE: 111173840(DDIT3)
PCAD: 102979652(DDIT3)
ECB: 100053417(DDIT3)
EPZ: 103559784(DDIT3)
EAI: 106833003(DDIT3)
MYB: 102255226(DDIT3)
MYD: 102764039(DDIT3)
MNA: 107546204(DDIT3)
HAI: 109390744(DDIT3)
DRO: 112319047(DDIT3)
PALE: 102890557(DDIT3)
RAY: 107501502(DDIT3)
MJV: 108409974(DDIT3)
LAV: 100660941(DDIT3)
TMU: 101361189
SHR: 100931338(DDIT3)
PCW: 110210977(DDIT3)
OAA: 103167225(DDIT3)
GGA: 100857832(DDIT3)
NMEL: 110402723
APLA: 101802390(DDIT3)
ACYG: 106049589(DDIT3)
LSR: 116184551(DDIT3)
PMAJ: 107199033(DDIT3)
NNI: 104019181(DDIT3)
ASN: 102384643(DDIT3)
AMJ: 102574043(DDIT3)
PSS: 102448363(DDIT3)
CMY: 102934528(DDIT3)
CPIC: 101947222(DDIT3)
ACS: 100567470(ddit3)
PVT: 110070828(DDIT3)
PBI: 103050195(DDIT3)
PMUR: 107293466(DDIT3)
TSR: 106552745(DDIT3)
PMUA: 114592937(DDIT3)
GJA: 107118957(DDIT3)
XLA: 108709861(ddit3.S) 398615(ddit3.L)
XTR: 733816(ddit3)
NPR: 108797835(DDIT3)
DRE: 561924(ddit3)
SRX: 107734605(ddit3)
SANH: 107683613(ddit3)
SGH: 107566410(ddit3)
IPU: 108271880(ddit3)
PHYP: 113533348(ddit3)
AMEX: 103022996(ddit3)
EEE: 113578011(ddit3)
TRU: 101061813(ddit3)
LCO: 104919971(ddit3)
NCC: 104968149(ddit3)
MZE: 101473986(ddit3)
ONL: 100711221(ddit3)
OLA: 101163653(ddit3)
XMA: 102237930(ddit3)
XCO: 114135476(ddit3)
PRET: 103464404(ddit3)
CVG: 107102812(ddit3)
NFU: 107385332(ddit3)
KMR: 108231469(ddit3)
ALIM: 106514742(ddit3)
AOCE: 111576947(ddit3)
CSEM: 103386391(ddit3)
POV: 109635636(ddit3)
LCF: 108884828(ddit3)
SDU: 111223952(ddit3)
SLAL: 111659798(ddit3)
HCQ: 109510628(ddit3)
BPEC: 110154550(ddit3)
MALB: 109965745(ddit3)
SASA: 106582666
OTW: 112254144
SALP: 111969676
ELS: 105028306(ddit3)
SFM: 108928403(ddit3)
PKI: 111835263(ddit3)
LCM: 102361121(DDIT3)
CMK: 103189067(ddit3)
 » show all
Oyadomari S, Mori M
Roles of CHOP/GADD153 in endoplasmic reticulum stress.
Cell Death Differ 11:381-9 (2004)
Yamaguchi H, Wang HG
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells.
J Biol Chem 279:45495-502 (2004)
Park JS, Luethy JD, Wang MG, Fargnoli J, Fornace AJ Jr, McBride OW, Holbrook NJ
Isolation, characterization and chromosomal localization of the human GADD153 gene.
Gene 116:259-67 (1992)

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