KEGG   ORTHOLOGY: K04503
Entry
K04503                      KO                                     

Name
CCND1
Definition
G1/S-specific cyclin-D1
Pathway
ko01522  Endocrine resistance
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04152  AMPK signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04340  Hedgehog signaling pathway
ko04371  Apelin signaling pathway
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04921  Oxytocin signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04934  Cushing syndrome
ko05160  Hepatitis C
ko05162  Measles
ko05163  Human cytomegalovirus infection
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05210  Colorectal cancer
ko05212  Pancreatic cancer
ko05213  Endometrial cancer
ko05214  Glioma
ko05215  Prostate cancer
ko05216  Thyroid cancer
ko05218  Melanoma
ko05219  Bladder cancer
ko05220  Chronic myeloid leukemia
ko05221  Acute myeloid leukemia
ko05222  Small cell lung cancer
ko05223  Non-small cell lung cancer
ko05224  Breast cancer
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05416  Viral myocarditis
Disease
H00006  Hairy cell leukemia
H00010  Multiple myeloma
H00016  Oral cancer
H00017  Esophageal cancer
H00031  Breast cancer
H00055  Laryngeal cancer
H00559  von Hippel-Lindau syndrome
H01464  Mantle cell lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04340 Hedgehog signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04390 Hippo signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04371 Apelin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04630 JAK-STAT signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04068 FoxO signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04151 PI3K-Akt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04152 AMPK signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K04503  CCND1; G1/S-specific cyclin-D1
   04115 p53 signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04218 Cellular senescence
    K04503  CCND1; G1/S-specific cyclin-D1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04503  CCND1; G1/S-specific cyclin-D1
   04530 Tight junction
    K04503  CCND1; G1/S-specific cyclin-D1
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04921 Oxytocin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04919 Thyroid hormone signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05206 MicroRNAs in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05205 Proteoglycans in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05203 Viral carcinogenesis
    K04503  CCND1; G1/S-specific cyclin-D1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05212 Pancreatic cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05225 Hepatocellular carcinoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05226 Gastric cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05214 Glioma
    K04503  CCND1; G1/S-specific cyclin-D1
   05216 Thyroid cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05221 Acute myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05220 Chronic myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05218 Melanoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05219 Bladder cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05215 Prostate cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05213 Endometrial cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05224 Breast cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05222 Small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05223 Non-small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K04503  CCND1; G1/S-specific cyclin-D1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04503  CCND1; G1/S-specific cyclin-D1
   04934 Cushing syndrome
    K04503  CCND1; G1/S-specific cyclin-D1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05160 Hepatitis C
    K04503  CCND1; G1/S-specific cyclin-D1
   05162 Measles
    K04503  CCND1; G1/S-specific cyclin-D1
   05163 Human cytomegalovirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05169 Epstein-Barr virus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05165 Human papillomavirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04503  CCND1; G1/S-specific cyclin-D1
Genes
HSA: 595(CCND1)
PTR: 747442(CCND1)
PPS: 100995605(CCND1)
GGO: 101130447(CCND1)
PON: 100171625(CCND1)
NLE: 100605736(CCND1)
MCC: 574320(CCND1)
MCF: 102135329(CCND1)
CSAB: 103246489(CCND1)
RRO: 104677168(CCND1)
RBB: 108538745(CCND1)
CJC: 100399312
SBQ: 101047858(CCND1)
MMU: 12443(Ccnd1)
MCAL: 110298189(Ccnd1)
MPAH: 110322378(Ccnd1)
RNO: 58919(Ccnd1)
MUN: 110546940(Ccnd1)
CGE: 100689063(Ccnd1)
NGI: 103751498(Ccnd1)
HGL: 101712621(Ccnd1)
CCAN: 109696351(Ccnd1)
TUP: 102490651(CCND1)
CFA: 449028(CCND1)
VVP: 112924157(CCND1)
AML: 100469787(CCND1)
UMR: 103671139(CCND1)
UAH: 113243982(CCND1)
ORO: 101371532(CCND1)
ELK: 111149458
FCA: 100037407(CCND1)
PTG: 102959906(CCND1)
PPAD: 109246902(CCND1)
AJU: 106971167(CCND1)
BTA: 524530(CCND1)
BOM: 102270546(CCND1)
BIU: 109554439(CCND1)
BBUB: 102411133(CCND1)
CHX: 102169650(CCND1)
OAS: 100144763(CCND1)
SSC: 100738589(CCND1)
CFR: 102518309(CCND1)
CDK: 105104393(CCND1)
BACU: 103013404(CCND1)
LVE: 103090612(CCND1)
OOR: 101273294(CCND1)
DLE: 111183632(CCND1)
PCAD: 102996914(CCND1)
ECB: 102149114(CCND1)
EAI: 106844248(CCND1)
MYB: 102263484(CCND1)
MYD: 102759793(CCND1)
MNA: 107537434(CCND1)
HAI: 109389297(CCND1)
DRO: 112317273(CCND1)
PALE: 102885330(CCND1)
RAY: 107503391(CCND1)
MJV: 108388480(CCND1)
LAV: 100669703(CCND1)
TMU: 101359745
MDO: 100013257(CCND1)
SHR: 100917462(CCND1)
PCW: 110197171(CCND1)
OAA: 100075081(CCND1)
GGA: 396341(CCND1)
MGP: 100539759(CCND1)
CJO: 107314428(CCND1)
NMEL: 110400907(CCND1)
APLA: 101800639(CCND1)
ACYG: 106044779(CCND1)
TGU: 100231612(CCND1)
LSR: 110469631(CCND1)
SCAN: 103822217(CCND1)
GFR: 102042858(CCND1)
FAB: 101807319(CCND1)
PHI: 102099659(CCND1)
PMAJ: 107205992(CCND1)
CCAE: 111930656(CCND1)
CCW: 104697629(CCND1)
ETL: 114067926(CCND1)
FPG: 101914937(CCND1)
FCH: 102053036(CCND1)
CLV: 102086245(CCND1)
EGZ: 104124693(CCND1)
NNI: 104009408(CCND1)
ACUN: 113481227(CCND1)
PADL: 103925769(CCND1)
AAM: 106498229(CCND1)
ASN: 102378816(CCND1)
AMJ: 102563714(CCND1)
PSS: 102457993(CCND1)
CMY: 102947923(CCND1)
CPIC: 101943958(CCND1)
ACS: 100563772(ccnd1)
PVT: 110073542(CCND1)
PBI: 103066913(CCND1)
PMUR: 107285821(CCND1)
TSR: 106546690(CCND1)
PMUA: 114596879(CCND1)
GJA: 107121511(CCND1)
XLA: 108697837 379161(ccnd1.S) 379937(ccnd1.L) 447541 447748(ccndx.L)
XTR: 448045(ccnd1) 548862(ccndx)
NPR: 108785450(CCND1) 108793412
DRE: 30222(ccnd1)
CCAR: 109093191(ccnd1)
IPU: 108271119(ccnd1)
PHYP: 113528462 113536429(ccnd1)
AMEX: 103031956(ccnd1)
EEE: 113578962(ccnd1) 113588422
TRU: 101061278(ccnd1)
LCO: 104937240(ccnd1) 104939589
NCC: 104950786(ccnd1) 104967413
MZE: 101467298 101485361(ccnd1)
ONL: 100691051(ccnd1) 100691373
OLA: 101169672(ccnd1)
XMA: 102233074(ccnd1)
XCO: 114143123(ccnd1)
PRET: 103462287(ccnd1)
CVG: 107096221(ccnd1)
NFU: 107374449(ccnd1)
KMR: 108237918(ccnd1)
ALIM: 106510985(ccnd1)
AOCE: 111576239(ccnd1)
CSEM: 103379080 103379853(ccnd1)
POV: 109625110(ccnd1) 109642994
SDU: 111221119(ccnd1) 111234824
BPEC: 110169262(ccnd1) 110174870
MALB: 109967859(ccnd1)
ELS: 105017289(ccnd1) 105018279
SFM: 108940463 108941209(ccnd1)
PKI: 111851863
LCM: 102361167(CCND1) 102367471
TCA: 660655
FCY: FRACYDRAFT_140762(dsCyc9b)
 » show all
Reference
PMID:1826542
  Authors
Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A
  Title
A novel cyclin encoded by a bcl1-linked candidate oncogene.
  Journal
Nature 350:512-5 (1991)
DOI:10.1038/350512a0
  Sequence
[hsa:595]
LinkDB

KEGG   ORTHOLOGY: K10151
Entry
K10151                      KO                                     

Name
CCND2
Definition
G1/S-specific cyclin-D2
Pathway
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04340  Hedgehog signaling pathway
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04630  JAK-STAT signaling pathway
ko04917  Prolactin signaling pathway
ko05162  Measles
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05203  Viral carcinogenesis
ko05206  MicroRNAs in cancer
Disease
H00023  Testicular cancer
H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04340 Hedgehog signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04390 Hippo signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04630 JAK-STAT signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04068 FoxO signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04151 PI3K-Akt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K10151  CCND2; G1/S-specific cyclin-D2
   04115 p53 signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04218 Cellular senescence
    K10151  CCND2; G1/S-specific cyclin-D2
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10151  CCND2; G1/S-specific cyclin-D2
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05202 Transcriptional misregulation in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05206 MicroRNAs in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05203 Viral carcinogenesis
    K10151  CCND2; G1/S-specific cyclin-D2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05162 Measles
    K10151  CCND2; G1/S-specific cyclin-D2
   05169 Epstein-Barr virus infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05165 Human papillomavirus infection
    K10151  CCND2; G1/S-specific cyclin-D2
Genes
HSA: 894(CCND2)
PTR: 747123(CCND2)
PPS: 100990850(CCND2)
GGO: 101139749(CCND2)
PON: 100457978(CCND2)
NLE: 100585770(CCND2)
MCC: 710379(CCND2)
MCF: 102119572(CCND2)
CSAB: 103218410(CCND2)
RRO: 104658979(CCND2)
RBB: 108536489(CCND2)
CJC: 100390172(CCND2)
SBQ: 101049141(CCND2)
MMU: 12444(Ccnd2)
MCAL: 110296334(Ccnd2)
MPAH: 110315929(Ccnd2)
RNO: 64033(Ccnd2)
MUN: 110548628(Ccnd2)
CGE: 100771544(Ccnd2)
NGI: 103727547(Ccnd2)
HGL: 101721480(Ccnd2)
OCU: 100009036(CCND2)
TUP: 102479902(CCND2)
CFA: 611782(CCND2)
VVP: 112917379(CCND2)
AML: 100471517(CCND2)
UMR: 103675743(CCND2)
UAH: 113258003(CCND2)
ORO: 101363193(CCND2)
ELK: 111159766
FCA: 101090950(CCND2)
PTG: 102970259(CCND2)
PPAD: 109276198(CCND2)
AJU: 106965383(CCND2)
BTA: 615414(CCND2)
BOM: 102272576(CCND2)
BIU: 109559745(CCND2)
BBUB: 102410004(CCND2)
CHX: 102180657(CCND2)
OAS: 100147799(CCND2)
SSC: 397162(CCND2)
CFR: 116661359(CCND2)
CDK: 105091327(CCND2)
BACU: 103002964(CCND2)
LVE: 103077970(CCND2)
OOR: 101274693(CCND2)
DLE: 111176638(CCND2)
PCAD: 102981679(CCND2)
ECB: 100051150(CCND2)
EPZ: 103567717(CCND2)
EAI: 106831500(CCND2)
MYB: 102254218(CCND2)
MYD: 102755701(CCND2)
MNA: 107538904(CCND2)
HAI: 109392488(CCND2)
DRO: 112312821(CCND2)
PALE: 102892640(CCND2)
RAY: 107513450(CCND2)
MJV: 108403976(CCND2)
LAV: 100668070(CCND2)
TMU: 101351510
MDO: 100016259(CCND2)
SHR: 100915359(CCND2)
PCW: 110218698(CCND2)
OAA: 100088940(CCND2)
GGA: 374047(CCND2)
MGP: 104909362
CJO: 107318017(CCND2)
NMEL: 110390646(CCND2)
APLA: 101802600(CCND2)
ACYG: 106046294(CCND2)
TGU: 100224096(CCND2)
LSR: 110479030(CCND2)
SCAN: 103819603(CCND2)
GFR: 102034688(CCND2)
FAB: 101818224(CCND2)
PHI: 102114518(CCND2)
PMAJ: 107204709(CCND2)
CCAE: 111930045(CCND2)
CCW: 104696177(CCND2)
ETL: 114067087(CCND2)
FPG: 101920354(CCND2)
FCH: 102053549(CCND2)
CLV: 102093196(CCND2)
EGZ: 104124210(CCND2)
NNI: 104021822(CCND2)
PADL: 103917223(CCND2)
AAM: 106489562(CCND2)
AMJ: 102564576(CCND2)
PSS: 102462674(CCND2)
CMY: 102931445(CCND2)
CPIC: 101939404(CCND2)
GJA: 107110411(CCND2)
XLA: 373667(ccnd2.L) 734882(ccnd2.S)
XTR: 100038071(ccnd2)
NPR: 108788361(CCND2)
DRE: 565038(ccnd2b) 799608(ccnd2a)
IPU: 100528326(ccnd2) 108279704(CCND2)
AMEX: 103031397(ccnd2) 111193357
LCM: 102345953 102351286(CCND2)
CMK: 103182468(ccnd3) 103185578(ccnd2)
RTP: 109931888
BFO: 118406671
CIN: 100186373
SKO: 100303589(ccnd)
DME: Dmel_CG9096(CycD)
DER: 6550709
DSE: 6620005
DSI: Dsimw501_GD15773(Dsim_GD15773)
DSR: 110181715
DPE: 6603470
DMN: 117186171
DWI: 6652925
DHE: 111596963
LCQ: 111677893
AME: 413183
BIM: 100744328
BTER: 100642333
CCAL: 108623408
OBB: 114875760
SOC: 105196203
MPHA: 105830325
AEC: 105149790
ACEP: 105619259
PBAR: 105427311
VEM: 105565318
HST: 105191023
DQU: 106748961
CFO: 105248357
LHU: 105676942
PGC: 109855101
OBO: 105284703
PCF: 106790317
NVI: 100117434(cycD)
CSOL: 105362588
MDL: 103571676
DPA: 109541632
BMOR: 100862781(cycD)
BMAN: 114245331
PMAC: 106708805
PRAP: 110996554
HAW: 110372374
TNL: 113508375
PXY: 105385267
DNX: 107168411
BTAB: 109039503
CLEC: 106666256
FCD: 110851356
DPTE: 113798117
CSCU: 111630486
PTEP: 107457517
CEL: CELE_Y38F1A.5(cyd-1)
CBR: CBG02768(Cbr-cyd-1)
PCAN: 112566123
CRG: 105330764
MYI: 110454764
OBI: 106878898
LAK: 106173892
SHX: MS3_06539
EGL: EGR_02547
NVE: 5500914
EPA: 110247806
ADF: 107334967
AMIL: 114962504
PDAM: 113677260
SPIS: 111345418
DGT: 114520980
HMG: 100198325
 » show all
Reference
PMID:1386336
  Authors
Xiong Y, Menninger J, Beach D, Ward DC
  Title
Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.
  Journal
Genomics 13:575-84 (1992)
DOI:10.1016/0888-7543(92)90127-E
  Sequence
[hsa:894]
Reference
PMID:9178893
  Authors
Sweeney KJ, Sarcevic B, Sutherland RL, Musgrove EA
  Title
Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells.
  Journal
Oncogene 14:1329-40 (1997)
DOI:10.1038/sj.onc.1200951
  Sequence
[hsa:894]
Reference
  Authors
Jena N, Deng M, Sicinska E, Sicinski P, Daley GQ
  Title
Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.
  Journal
Cancer Res 62:535-41 (2002)
  Sequence
[mmu:12444]
LinkDB

KEGG   ORTHOLOGY: K10152
Entry
K10152                      KO                                     

Name
CCND3
Definition
G1/S-specific cyclin-D3
Pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04310  Wnt signaling pathway
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04630  JAK-STAT signaling pathway
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
Disease
H00010  Multiple myeloma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04390 Hippo signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04630 JAK-STAT signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04151 PI3K-Akt signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K10152  CCND3; G1/S-specific cyclin-D3
   04115 p53 signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04218 Cellular senescence
    K10152  CCND3; G1/S-specific cyclin-D3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10152  CCND3; G1/S-specific cyclin-D3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10152  CCND3; G1/S-specific cyclin-D3
   05203 Viral carcinogenesis
    K10152  CCND3; G1/S-specific cyclin-D3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10152  CCND3; G1/S-specific cyclin-D3
   05164 Influenza A
    K10152  CCND3; G1/S-specific cyclin-D3
   05162 Measles
    K10152  CCND3; G1/S-specific cyclin-D3
   05169 Epstein-Barr virus infection
    K10152  CCND3; G1/S-specific cyclin-D3
   05165 Human papillomavirus infection
    K10152  CCND3; G1/S-specific cyclin-D3
Genes
HSA: 896(CCND3)
PTR: 462689(CCND3)
PPS: 100972595(CCND3)
GGO: 101130628(CCND3)
PON: 100452570(CCND3)
NLE: 100580170(CCND3)
MCC: 695215(CCND3)
MCF: 101865999(CCND3)
CSAB: 103221504(CCND3)
RRO: 104667309(CCND3)
RBB: 108533501(CCND3)
CJC: 100408249(CCND3)
SBQ: 101047749(CCND3)
MMU: 12445(Ccnd3)
MCAL: 110312516(Ccnd3)
MPAH: 110335402(Ccnd3)
RNO: 25193(Ccnd3)
MUN: 110550225(Ccnd3)
CGE: 100766025(Ccnd3)
NGI: 103725891(Ccnd3)
HGL: 101708062(Ccnd3)
CCAN: 109682157(Ccnd3)
OCU: 100009038(CCND3)
TUP: 102499577(CCND3)
CFA: 608847(CCND3)
VVP: 112913983(CCND3)
AML: 100479467(CCND3)
UMR: 103664092(CCND3)
UAH: 113261302(CCND3)
ORO: 101372891(CCND3)
ELK: 111147855
FCA: 101101311(CCND3)
PTG: 102970915(CCND3)
PPAD: 109271613(CCND3)
AJU: 106974052(CCND3)
BTA: 540547(CCND3)
BOM: 102268077(CCND3)
BIU: 109577151(CCND3)
BBUB: 102412107(CCND3)
CHX: 102190470(CCND3)
OAS: 100147798(CCND3)
SSC: 780426(CCND3)
CFR: 102524562(CCND3)
CDK: 105086756(CCND3)
BACU: 103007761(CCND3)
LVE: 103072491(CCND3)
OOR: 101274576(CCND3)
DLE: 111178811(CCND3)
PCAD: 102987349(CCND3)
ECB: 100066590(CCND3)
EPZ: 103563494(CCND3)
EAI: 106824516(CCND3)
MYB: 102252389(CCND3)
MYD: 102756923(CCND3)
MNA: 107536896(CCND3)
HAI: 109382891(CCND3)
DRO: 112302074(CCND3)
PALE: 102881884(CCND3)
RAY: 107501938(CCND3)
MJV: 108405335(CCND3)
LAV: 100668683(CCND3)
TMU: 101351688
MDO: 100027538(CCND3)
SHR: 100921166(CCND3)
PCW: 110203289(CCND3)
OAA: 100088334(CCND3)
GGA: 419928(CCND3)
MGP: 100546832(CCND3)
CJO: 107324823(CCND3)
NMEL: 110388224(CCND3)
APLA: 101790685(CCND3)
ACYG: 106045863(CCND3)
TGU: 100218837(CCND3)
LSR: 110477163(CCND3)
SCAN: 115484353(CCND3)
GFR: 102033692(CCND3)
FAB: 101819978(CCND3)
PHI: 102106455(CCND3)
PMAJ: 107214873
CCAE: 111939904(CCND3)
CCW: 104692524(CCND3)
FPG: 101913539(CCND3)
FCH: 102059828(CCND3)
CLV: 102090134(CCND3)
EGZ: 104125735(CCND3)
NNI: 104013148(CCND3)
ACUN: 113488829(CCND3)
PADL: 103919864(CCND3)
AAM: 106483949(CCND3)
ASN: 102386423(CCND3)
AMJ: 102560290(CCND3)
PSS: 102445982(CCND3)
CMY: 102940098(CCND3)
CPIC: 101940970(CCND3)
ACS: 100566165(ccnd3)
PVT: 110078878 110080664(CCND3)
PBI: 103060947(CCND3)
PMUR: 107293964(CCND3)
TSR: 106540193(CCND3)
PMUA: 114599266(CCND3)
GJA: 107119188(CCND3)
DRE: 449996(ccnd3)
SRX: 107723118
SANH: 107656907
SGH: 107572366
CCAR: 109088524
IPU: 108281084(ccnd3)
PHYP: 113539684(ccnd3)
AMEX: 103045792(ccnd3)
LCO: 104927998(ccnd3)
NCC: 104957029
MZE: 101472513(ccnd3)
ONL: 100690263
OLA: 101165722
XMA: 102221373
XCO: 114136140
PRET: 103465178(ccnd3)
CVG: 107085628(ccnd3)
NFU: 107385769(ccnd3)
KMR: 108235802(ccnd3)
ALIM: 106516142(ccnd3)
AOCE: 111574366
CSEM: 103385889(ccnd3)
POV: 109629233(ccnd3)
LCF: 108886479(ccnd3)
SDU: 111222077
SLAL: 111660864(ccnd3)
HCQ: 109522291
BPEC: 110168781
MALB: 109964433(ccnd3)
SASA: 106583090
OTW: 112254562
SALP: 111970058
ELS: 105017123(ccnd3)
PKI: 111852988(ccnd3)
ATD: 109601133
BMOR: 101738852
BMAN: 114241730
PMAC: 106707770
PRAP: 110992868
HAW: 110378432
TNL: 113508047
BTAB: 109034725
CSCU: 111622028
PTEP: 107448152
TSP: Tsp_06217
 » show all
Reference
  Authors
Liu W, Sun M, Jiang J, Shen X, Sun Q, Liu W, Shen H, Gu J
  Title
Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity.
  Journal
Biochem Biophys Res Commun 321:954-60 (2004)
DOI:10.1016/j.bbrc.2004.07.053
  Sequence
[hsa:896]
Reference
PMID:1383201
  Authors
Motokura T, Keyomarsi K, Kronenberg HM, Arnold A
  Title
Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 proto-oncogene.
  Journal
J Biol Chem 267:20412-5 (1992)
  Sequence
[hsa:896]
LinkDB

KEGG   ORTHOLOGY: K06626
Entry
K06626                      KO                                     

Name
CCNE
Definition
G1/S-specific cyclin-E1
Pathway
ko04110  Cell cycle
ko04114  Oocyte meiosis
ko04115  p53 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04218  Cellular senescence
ko04391  Hippo signaling pathway - fly
ko04934  Cushing syndrome
ko05161  Hepatitis B
ko05162  Measles
ko05165  Human papillomavirus infection
ko05166  Human T-cell leukemia virus 1 infection
ko05169  Epstein-Barr virus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
ko05206  MicroRNAs in cancer
ko05215  Prostate cancer
ko05222  Small cell lung cancer
ko05226  Gastric cancer
Disease
H00018  Gastric cancer
H00055  Laryngeal cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04391 Hippo signaling pathway - fly
    K06626  CCNE; G1/S-specific cyclin-E1
   04151 PI3K-Akt signaling pathway
    K06626  CCNE; G1/S-specific cyclin-E1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06626  CCNE; G1/S-specific cyclin-E1
   04114 Oocyte meiosis
    K06626  CCNE; G1/S-specific cyclin-E1
   04115 p53 signaling pathway
    K06626  CCNE; G1/S-specific cyclin-E1
   04218 Cellular senescence
    K06626  CCNE; G1/S-specific cyclin-E1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05206 MicroRNAs in cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05203 Viral carcinogenesis
    K06626  CCNE; G1/S-specific cyclin-E1
  09162 Cancer: specific types
   05226 Gastric cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05215 Prostate cancer
    K06626  CCNE; G1/S-specific cyclin-E1
   05222 Small cell lung cancer
    K06626  CCNE; G1/S-specific cyclin-E1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K06626  CCNE; G1/S-specific cyclin-E1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06626  CCNE; G1/S-specific cyclin-E1
   05161 Hepatitis B
    K06626  CCNE; G1/S-specific cyclin-E1
   05162 Measles
    K06626  CCNE; G1/S-specific cyclin-E1
   05169 Epstein-Barr virus infection
    K06626  CCNE; G1/S-specific cyclin-E1
   05165 Human papillomavirus infection
    K06626  CCNE; G1/S-specific cyclin-E1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K06626  CCNE; G1/S-specific cyclin-E1
   03036 Chromosome and associated proteins
    K06626  CCNE; G1/S-specific cyclin-E1
DNA replication proteins [BR:ko03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    K06626  CCNE; G1/S-specific cyclin-E1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Cyclins
    K06626  CCNE; G1/S-specific cyclin-E1
Genes
HSA: 898(CCNE1) 9134(CCNE2)
PTR: 455914(CCNE1) 464292(CCNE2)
PPS: 100972365(CCNE1) 100982783(CCNE2)
GGO: 101134470(CCNE1) 101153263(CCNE2)
PON: 100438282(CCNE2) 100461587(CCNE1)
NLE: 100602200(CCNE2) 100607751(CCNE1)
MCC: 700382(CCNE2) 700589(CCNE1)
MCF: 102137714(CCNE1) 102138564(CCNE2)
CSAB: 103235482(CCNE1) 103237156(CCNE2)
RRO: 104656155(CCNE1) 104660331(CCNE2)
RBB: 108530611(CCNE1) 108539896(CCNE2)
CJC: 100396520(CCNE1) 100403750(CCNE2)
SBQ: 101036684(CCNE2) 101052282(CCNE1)
MMU: 12447(Ccne1) 12448(Ccne2)
MCAL: 110292124(Ccne2) 110298604(Ccne1)
MPAH: 110324083(Ccne1) 110338930(Ccne2)
RNO: 25729(Ccne1) 362485(Ccne2)
MUN: 110545702(Ccne1) 110561277(Ccne2)
CGE: 100753358(Ccne1) 100760464(Ccne2)
NGI: 103740830(Ccne1) 103745830(Ccne2)
HGL: 101701725(Ccne2) 101711961(Ccne1)
CCAN: 109693086(Ccne1) 109695602(Ccne2)
OCU: 100134864(CCNE1) 100134867(CCNE2)
TUP: 102468317(CCNE1) 102492088(CCNE2)
CFA: 484610(CCNE1) 487057(CCNE2)
VVP: 112928464(CCNE1) 112931227(CCNE2)
AML: 100471009(CCNE1) 100483627(CCNE2)
UMR: 103661328(CCNE1) 103661444(CCNE2)
UAH: 113244704(CCNE1) 113252919(CCNE2)
ORO: 101366323(CCNE2) 101382136(CCNE1)
FCA: 101085347(CCNE2) 101086192(CCNE1)
PTG: 102955833(CCNE2) 102966425(CCNE1)
PPAD: 109251568(CCNE1) 109269512(CCNE2)
AJU: 106974883(CCNE2) 106975766(CCNE1)
BTA: 533526(CCNE1) 538436(CCNE2)
BOM: 102271261(CCNE1) 102284697(CCNE2)
BIU: 109568476(CCNE2) 109572914(CCNE1)
BBUB: 102389005(CCNE1) 102390852(CCNE2)
CHX: 102184185(CCNE1) 102185672(CCNE2)
OAS: 101107124(CCNE1) 101109811(CCNE2)
SSC: 100512048(CCNE2) 100523248(CCNE1)
CFR: 102512815(CCNE2) 102516466(CCNE1)
CDK: 105085741(CCNE2) 105096784(CCNE1)
BACU: 102997538(CCNE2) 103008660(CCNE1)
LVE: 103078168(CCNE1) 103087546(CCNE2)
OOR: 101272657(CCNE1) 101285614(CCNE2)
DLE: 111180416(CCNE2) 111180958(CCNE1)
PCAD: 102980091(CCNE1) 102988829(CCNE2)
ECB: 100053882(CCNE1) 100055302(CCNE2)
EPZ: 103556279(CCNE1) 103567628(CCNE2)
EAI: 106831458(CCNE2) 106832401(CCNE1)
MYB: 102248984(CCNE2)
MYD: 102763547(CCNE2) 102769827(CCNE1)
MNA: 107534117(CCNE2) 107535865(CCNE1)
HAI: 109376215(CCNE2) 109383495(CCNE1)
DRO: 112296785(CCNE1) 112315543(CCNE2)
PALE: 102882260(CCNE1) 102882411(CCNE2)
RAY: 107502556(CCNE2) 107515884(CCNE1)
MJV: 108385232(CCNE1) 108396147(CCNE2)
LAV: 100659451(CCNE1) 100668342(CCNE2)
MDO: 100014623(CCNE1) 100022654(CCNE2) 100030421
SHR: 100920942(CCNE1) 100924454(CCNE2)
PCW: 110195790(CCNE2) 110207433(CCNE1)
OAA: 100075784(CCNE2) 100087197(CCNE1)
GGA: 420231(CCNE2) 426117(CCNE1)
MGP: 100545829(CCNE2) 104913010
CJO: 107310377(CCNE2) 107319346(CCNE1)
NMEL: 110393757(CCNE2) 110404443(CCNE1)
APLA: 101792020(CCNE2) 101792902(CCNE1)
ACYG: 106030499(CCNE2) 106039599(CCNE1)
TGU: 100220841(CCNE1) 105759030(CCNE2)
LSR: 110476268(CCNE1) 110477449(CCNE2)
SCAN: 103813607(CCNE2) 103816602(CCNE1)
GFR: 102040569(CCNE1) 102043017(CCNE2)
FAB: 101809310(CCNE2) 101821269(CCNE1)
PHI: 102111744(CCNE2) 102114128(CCNE1)
PMAJ: 107200409(CCNE2) 107210040(CCNE1)
CCAE: 111924530(CCNE2) 111934658(CCNE1)
CCW: 104687430(CCNE1) 104692739(CCNE2)
ETL: 114060091(CCNE2) 114063486(CCNE1)
FPG: 101913703(CCNE2) 101923204(CCNE1)
FCH: 102047310(CCNE2) 102059423(CCNE1)
CLV: 102091343(CCNE1) 102094830(CCNE2)
EGZ: 104125564(CCNE1) 104125860(CCNE2)
NNI: 104013280(CCNE1) 104016423(CCNE2)
ACUN: 113476163(CCNE2) 113484462(CCNE1)
PADL: 103913786(CCNE1) 103917293(CCNE2)
AAM: 106483300(CCNE1) 106483881(CCNE2)
ASN: 102368597(CCNE2) 102382034(CCNE1)
AMJ: 102568414(CCNE2) 102569019(CCNE1)
PSS: 102445271(CCNE2) 102460990(CCNE1)
CMY: 102931864(CCNE2) 102941488(CCNE1)
CPIC: 101940805(CCNE1) 101946480(CCNE2)
ACS: 100553527(ccne1) 100563792(ccne2)
PVT: 110069793(CCNE1) 110074768(CCNE2)
PBI: 103052775(CCNE1) 103066008(CCNE2)
PMUR: 107289143(CCNE2) 107292735(CCNE1)
TSR: 106551743(CCNE2) 106555427(CCNE1)
PMUA: 114600411(CCNE2) 114602273(CCNE1)
GJA: 107109268(CCNE2) 107111199(CCNE1)
XLA: 380219(ccne2.L) 397840(ccne1.L) 397841(ccne1.S) 495419(ccne2.S)
XTR: 549021(ccne2) 549082(ccne1)
NPR: 108784132(CCNE1) 108795903(CCNE2)
DRE: 30188(ccne1) 415165(ccne2)
AMEX: 103028876 103030457(ccne2) 103042001(ccne1)
EEE: 113572719(ccne2) 113586489 113591781(ccne1)
OLA: 101155592(ccne1) 101172438(ccne2)
XMA: 102233990(ccne2) 102234620(ccne1)
XCO: 114139015(ccne2) 114142529(ccne1)
PRET: 103462253(ccne1) 103477592(ccne2)
CVG: 107086797 107092298(ccne2)
NFU: 107374180(ccne1) 107379284(ccne2)
KMR: 108237878(ccne1) 108240335(ccne2)
ALIM: 106516743(ccne1) 106524900(ccne2)
CSEM: 103378619(ccne1) 103388039(ccne2)
SLAL: 111644688(ccne2) 111649541 111672273(ccne1)
SASA: 100195405(ccne2) 106562012 106605376(ccne2)
ELS: 105019239(ccne2) 105022734(ccne1)
LCM: 102363290(CCNE2) 102366176(CCNE1)
CMK: 103175366(ccne2) 103176046(ccne1)
RTP: 109924247(ccne2) 109932834(ccne1)
BFO: 118418491
CIN: 100185796
SPU: 579860
APLC: 110980132
SKO: 100371723
DME: Dmel_CG3938(CycE)
DER: 6542978
DSE: 6611388
DSI: Dsimw501_GD21944(Dsim_GD21944)
DSR: 110185949
DPE: 6603382
DMN: 108162742
DWI: 6644016
DAZ: 108611979
DNV: 115563304
DHE: 111596331
MDE: 101893514
LCQ: 111684363
AAG: 5571432
AME: 411327
BIM: 100743743
BTER: 100643771
CCAL: 108622673
OBB: 114874054
SOC: 105195892
MPHA: 105831791
AEC: 105153804
ACEP: 105624868
PBAR: 105424288
VEM: 105560343
HST: 105184328
DQU: 106750123
CFO: 105252802
LHU: 105671051
PGC: 109855838
OBO: 105276425
PCF: 106791295
NVI: 100114765
CSOL: 105361015
MDL: 103577463
TCA: 657290
DPA: 109536939
ATD: 109598037
NVL: 108566345
BMOR: 100216493(Cyce)
BMAN: 114244023
PMAC: 106713917
PRAP: 110994971
HAW: 110381830
TNL: 113496456
PXY: 105382581
API: 100159237
DNX: 107167038
AGS: 114125620
RMD: 113551412
BTAB: 109043120
CLEC: 106670511
ZNE: 110838908
FCD: 110842390
TUT: 107367273
DPTE: 113792814
PTEP: 107455437
CEL: CELE_C37A2.4(cye-1)
CBR: CBG12774(Cbr-cye-1)
PCAN: 112577049
CRG: 105332299
MYI: 110443792
OBI: 106874854
NVE: 5505144
EPA: 110253010
ADF: 107345701
AMIL: 114954247
PDAM: 113680591
SPIS: 111337022
DGT: 114517040
HMG: 100211715
AQU: 100634156
 » show all
Reference
  Authors
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK
  Title
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines.
  Journal
Nature 413:311-6 (2001)
DOI:10.1038/35095068
  Sequence
Reference
PMID:1833068
  Authors
Koff A, Cross F, Fisher A, Schumacher J, Leguellec K, Philippe M, Roberts JM
  Title
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.
  Journal
Cell 66:1217-28 (1991)
DOI:10.1016/0092-8674(91)90044-Y
  Sequence
[hsa:898]
LinkDB

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