KEGG   ORTHOLOGY: K04684
Entry
K04684                      KO                                     

Name
SP1
Definition
transcription factor Sp1
Pathway
map01522  Endocrine resistance
map04137  Mitophagy - animal
map04350  TGF-beta signaling pathway
map04915  Estrogen signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05163  Human cytomegalovirus infection
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05224  Breast cancer
map05231  Choline metabolism in cancer
map05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K04684  SP1; transcription factor Sp1
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K04684  SP1; transcription factor Sp1
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04684  SP1; transcription factor Sp1
   04928 Parathyroid hormone synthesis, secretion and action
    K04684  SP1; transcription factor Sp1
   04927 Cortisol synthesis and secretion
    K04684  SP1; transcription factor Sp1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04684  SP1; transcription factor Sp1
   05202 Transcriptional misregulation in cancer
    K04684  SP1; transcription factor Sp1
   05231 Choline metabolism in cancer
    K04684  SP1; transcription factor Sp1
  09162 Cancer: specific types
   05224 Breast cancer
    K04684  SP1; transcription factor Sp1
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K04684  SP1; transcription factor Sp1
  09164 Neurodegenerative disease
   05016 Huntington disease
    K04684  SP1; transcription factor Sp1
   05017 Spinocerebellar ataxia
    K04684  SP1; transcription factor Sp1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K04684  SP1; transcription factor Sp1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04684  SP1; transcription factor Sp1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04684  SP1; transcription factor Sp1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04684  SP1; transcription factor Sp1
   03029 Mitochondrial biogenesis
    K04684  SP1; transcription factor Sp1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 SP/KLF family and related proteins
    K04684  SP1; transcription factor Sp1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Ubiquitas transcription factors
    K04684  SP1; transcription factor Sp1
Genes
HSA: 6667(SP1)
PTR: 451939(SP1)
PPS: 100985203(SP1)
PON: 100440745(SP1)
NLE: 100585963(SP1)
MCC: 702710(SP1)
MCF: 102115996(SP1)
CSAB: 103238395(SP1)
CATY: 105580268(SP1)
PANU: 116268873(SP1)
RRO: 104670595(SP1)
RBB: 108521535(SP1)
TFN: 117090035(SP1)
PTEH: 111541933
CJC: 100407824(SP1)
SBQ: 101048381(SP1)
MMUR: 105870777(SP1)
MMU: 20683(Sp1)
MCAL: 110310111(Sp1)
MPAH: 110334488(Sp1)
RNO: 24790(Sp1)
MCOC: 116080468(Sp1)
MUN: 110552322(Sp1)
CGE: 100767199(Sp1)
PLEU: 114696625(Sp1)
NGI: 103738561(Sp1)
HGL: 101697506(Sp1)
CCAN: 109684073(Sp1)
OCU: 100351317(SP1)
TUP: 102473003(SP1)
CFA: 486507(SP1)
VVP: 112921180(SP1)
VLG: 121479904(SP1)
AML: 100474983(SP1)
UMR: 103675530(SP1)
UAH: 113257555(SP1)
ORO: 101367562(SP1)
ELK: 111157856
MPUF: 101686835(SP1)
EJU: 114225869(SP1)
MLX: 118008792(SP1)
FCA: 101100227(SP1)
PTG: 102955984(SP1)
PPAD: 109249199(SP1)
AJU: 106983094(SP1)
HHV: 120247236(SP1)
BTA: 540741(SP1)
BOM: 102282294(SP1)
BIU: 109559035(SP1)
BBUB: 102392142(SP1)
CHX: 100860911(SP1)
OAS: 101104139(SP1)
ODA: 120858300(SP1)
SSC: 396575(SP1)
CFR: 102520683(SP1)
CDK: 105094564(SP1)
BACU: 103010578(SP1)
OOR: 101284508(SP1)
DLE: 111173942(SP1)
PCAD: 102973166(SP1)
ECB: 100629527(SP1)
EPZ: 103559402(SP1)
EAI: 106835289(SP1)
MYB: 102256096(SP1)
MYD: 102752526(SP1) 102753263
MMYO: 118650196(SP1)
MNA: 107528307(SP1)
HAI: 109391846(SP1)
DRO: 112318338(SP1)
AJM: 119043517(SP1)
MMF: 118623453(SP1)
PALE: 102894100(SP1)
RAY: 107509855(SP1)
MJV: 108387199
TOD: 119247989(SP1)
LAV: 100662543(SP1)
TMU: 101349790
SHR: 100930024(SP1)
PCW: 110194006(SP1)
OAA: 114814764(SP1)
GGA: 395303(SP1)
PCOC: 116234959(SP1)
MGP: 100539328(SP1)
CJO: 107306967(SP1)
NMEL: 110390879(SP1)
TGU: 115491349(SP1)
LSR: 110480534(SP1)
SCAN: 103825226(SP1)
PMOA: 120501829(SP1)
FAB: 101818755(SP1)
PHI: 102112711(SP1)
PMAJ: 107198749(SP1)
CCAE: 111940460(SP1)
ETL: 114072464(SP1)
FPG: 101921378(SP1)
FCH: 102046473(SP1)
CLV: 102091713(SP1)
EGZ: 104124794(SP1)
NNI: 104017530(SP1)
ACUN: 113490686(SP1)
PADL: 103925632(SP1)
AAM: 106487505(SP1)
ASN: 102370562(SP1)
AMJ: 102557884(SP1)
CPOO: 109323220(SP1)
PSS: 102450768(SP1)
CMY: 102943070(SP1)
CPIC: 101949432(SP1)
TST: 117888449(SP1)
CABI: 116828475(SP1)
ACS: 100553756(sp1)
PVT: 110074383(SP1)
PBI: 103052107(SP1)
PMUR: 107291239(SP1)
TSR: 106552859(SP1)
PGUT: 117662667(SP1)
PMUA: 114593046(SP1)
ZVI: 118077160(SP1)
GJA: 107119663(SP1)
XLA: 108709905(sp1.S) 431939(sp1.L)
XTR: 394744(sp1)
NPR: 108786826(SP1)
DRE: 324109(sp1)
SRX: 107742020(sp1) 107748519
SGH: 107575074
CAUA: 113068116(sp1)
IPU: 108254785(sp1)
PHYP: 113524457(sp1)
AMEX: 103027197(sp1)
EEE: 113581441(sp1)
TRU: 101071233(sp1)
LCO: 104919961(sp1)
NCC: 104962038
ELY: 117256362(sp1)
PLEP: 121957297(sp1)
SLUC: 116051354(sp1)
ECRA: 117943581(sp1)
PFLV: 114554650(sp1)
GAT: 120835455(sp1)
MSAM: 119885812(sp1)
CUD: 121507071(sp1)
MZE: 101477446(sp1)
ONL: 100690316(sp1)
OAU: 116320762(sp1)
OLA: 101161549(sp1)
OML: 112144742(sp1)
XMA: 102236306(sp1)
XCO: 114134954(sp1)
XHE: 116710631(sp1)
PRET: 103464412(sp1)
CVG: 107103259(sp1)
CTUL: 119789679(sp1)
NFU: 107385320(sp1)
KMR: 108231465(sp1)
ALIM: 106514730(sp1)
AOCE: 111583780(sp1)
CSEM: 103386384(sp1)
POV: 109635527(sp1)
LCF: 108884839(sp1)
SDU: 111224016(sp1)
SLAL: 111670201(sp1)
XGL: 120807114(sp1)
HCQ: 109510616(sp1)
BPEC: 110171184(sp1)
MALB: 109959387(sp1)
SASA: 106566174(sp1)
OTW: 112235852(sp1)
OMY: 110494799(sp1)
SALP: 112069701(sp1)
ELS: 105031425(sp1)
SFM: 108928412(sp1)
PKI: 111835274(sp1)
LOC: 102682631
PSPA: 121308931(sp1)
LCM: 102366212(SP1)
CMK: 103190683(sp1)
 » show all
Reference
  Authors
Infantino V, Convertini P, Iacobazzi F, Pisano I, Scarcia P, Iacobazzi V
  Title
Identification of a novel Sp1 splice variant as a strong transcriptional activator.
  Journal
Biochem Biophys Res Commun 412:86-91 (2011)
DOI:10.1016/j.bbrc.2011.07.047
  Sequence
[hsa:6667]
Reference
  Authors
Ding H, Benotmane AM, Suske G, Collen D, Belayew A
  Title
Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene.
  Journal
J Biol Chem 274:19573-80 (1999)
DOI:10.1074/jbc.274.28.19573
  Sequence
[hsa:6667]
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