KEGG   ORTHOLOGY: K04958
Entry
K04958                      KO                                     

Name
ITPR1
Definition
inositol 1,4,5-triphosphate receptor type 1
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04070  Phosphatidylinositol signaling system
ko04114  Oocyte meiosis
ko04140  Autophagy - animal
ko04210  Apoptosis
ko04218  Cellular senescence
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04745  Phototransduction - fly
ko04750  Inflammatory mediator regulation of TRP channels
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04929  GnRH secretion
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05016  Huntington disease
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05205  Proteoglycans in cancer
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04020 Calcium signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04070 Phosphatidylinositol signaling system
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04022 cGMP-PKG signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04210 Apoptosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04218 Cellular senescence
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04621 NOD-like receptor signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04625 C-type lectin receptor signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04929 GnRH secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04912 GnRH signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04915 Estrogen signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04921 Oxytocin signaling pathway
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04935 Growth hormone synthesis, secretion and action
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04918 Thyroid hormone synthesis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04928 Parathyroid hormone synthesis, secretion and action
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04924 Renin secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04925 Aldosterone synthesis and secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04927 Cortisol synthesis and secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09154 Digestive system
   04970 Salivary secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04971 Gastric acid secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04972 Pancreatic secretion
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09156 Nervous system
   04724 Glutamatergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04725 Cholinergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04728 Dopaminergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04726 Serotonergic synapse
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04720 Long-term potentiation
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04730 Long-term depression
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04723 Retrograde endocannabinoid signaling
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09157 Sensory system
   04745 Phototransduction - fly
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   04750 Inflammatory mediator regulation of TRP channels
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05012 Parkinson disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05016 Huntington disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05017 Spinocerebellar ataxia
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05020 Prion disease
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05022 Pathways of neurodegeneration - multiple diseases
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05163 Human cytomegalovirus infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3708(ITPR1)
PTR: 460134(ITPR1)
PPS: 100984884(ITPR1)
GGO: 101151145(ITPR1)
PON: 100445922(ITPR1)
NLE: 100587159(ITPR1)
MCC: 703669(ITPR1)
MCF: 101865389(ITPR1)
CSAB: 103227941(ITPR1)
RRO: 104664252(ITPR1)
RBB: 108528737(ITPR1)
CJC: 100385763(ITPR1)
SBQ: 101029556(ITPR1)
MMU: 16438(Itpr1)
MCAL: 110296867(Itpr1)
MPAH: 110317210(Itpr1)
RNO: 25262(Itpr1)
MUN: 110552142(Itpr1)
CGE: 100764450(Itpr1)
NGI: 103751203(Itpr1)
HGL: 101706047(Itpr1)
CCAN: 109699340(Itpr1)
OCU: 100009505(ITPR1)
TUP: 102473622(ITPR1)
CFA: 476548(ITPR1)
VVP: 112913302(ITPR1)
AML: 100467161(ITPR1)
UMR: 103669597(ITPR1)
UAH: 113257114(ITPR1)
ORO: 101367743(ITPR1)
ELK: 111144005
FCA: 101100546(ITPR1)
PTG: 102963245(ITPR1)
PPAD: 109254652(ITPR1)
AJU: 106978946(ITPR1)
BTA: 317697(ITPR1)
BOM: 102269088(ITPR1)
BIU: 109576135(ITPR1)
BBUB: 102412452(ITPR1)
CHX: 102188092(ITPR1)
OAS: 101108864(ITPR1)
SSC: 397454(ITPR1)
CFR: 102521814(ITPR1)
CDK: 105093156(ITPR1)
BACU: 103010644(ITPR1)
LVE: 103079294(ITPR1)
OOR: 101282737(ITPR1)
DLE: 111174169(ITPR1)
ECB: 100052808(ITPR1)
EPZ: 103550297(ITPR1)
EAI: 106848450(ITPR1)
MYB: 102262150(ITPR1)
MYD: 102755292(ITPR1)
MNA: 107529142(ITPR1)
HAI: 109395800(ITPR1)
DRO: 112309625(ITPR1)
PALE: 102894982(ITPR1)
RAY: 107504134(ITPR1)
MJV: 108395952(ITPR1)
LAV: 100665028(ITPR1)
TMU: 101346534
MDO: 100013305(ITPR1)
SHR: 100918532(ITPR1)
PCW: 110195613(ITPR1)
OAA: 100075749(ITPR1)
GGA: 395412(ITPR1)
MGP: 100540293(ITPR1)
CJO: 107319899(ITPR1)
NMEL: 110404652(ITPR1)
APLA: 101791594(ITPR1)
ACYG: 106036713(ITPR1)
TGU: 100229045(ITPR1)
LSR: 110469846(ITPR1)
SCAN: 103823703(ITPR1)
GFR: 102045318(ITPR1)
FAB: 101816592(ITPR1)
PHI: 102107950(ITPR1)
PMAJ: 107210255(ITPR1)
CCAE: 111934931(ITPR1)
CCW: 104683516(ITPR1)
ETL: 114062422(ITPR1)
FPG: 101916606(ITPR1)
FCH: 102050701(ITPR1)
CLV: 102095848(ITPR1)
EGZ: 104132649(ITPR1)
NNI: 104016945(ITPR1)
ACUN: 113484753(ITPR1)
PADL: 103922482(ITPR1)
AAM: 106489801(ITPR1)
ASN: 102379206(ITPR1)
AMJ: 102561752(ITPR1)
PSS: 102462538(ITPR1)
CMY: 102941719(ITPR1)
CPIC: 101945436(ITPR1)
ACS: 100568038(itpr1)
PVT: 110088203(ITPR1)
PBI: 103049895
PMUR: 107293430(ITPR1)
PMUA: 114591812(ITPR1)
GJA: 107116811(ITPR1)
XLA: 108714625 399254(itpr1.S)
XTR: 100493341(itpr1)
NPR: 108791910(ITPR1)
DRE: 100149388(itpr1b) 567611(itpr1a)
IPU: 108254919(itpr1)
PHYP: 113539752(itpr1) 113545832
AMEX: 103030168 103040877(itpr1)
EEE: 113575990
LCO: 104921973(itpr1) 104931270
NCC: 104955082(itpr1)
XMA: 102217419 102227088(itpr1)
XCO: 114135479 114136183(itpr1)
NFU: 107384050 107385796(itpr1)
KMR: 108235741 108244393(itpr1)
AOCE: 111569665 111575102(itpr1)
CSEM: 103385989(itpr1) 103386616
HCQ: 109521562(itpr1) 109522343
OTW: 112254359 112262812(itpr1)
SALP: 111966193(itpr1) 111969857
PKI: 111839848 111840603(itpr1)
LCM: 102361301(ITPR1)
CMK: 103185072(itpr1)
BFO: 118415973
CIN: 101243127
SPU: 594527
DME: Dmel_CG1063(Itpr)
DER: 6552808
DSE: 6620843
DSI: Dsimw501_GD19791(Dsim_GD19791)
DAN: 6500042
DSR: 110177231
DPE: 6591340
DMN: 108155501
DWI: 6642428
DNV: 108655982
DVI: 6630671
MDE: 101897637
AAG: 5564815
BIM: 100747875
BTER: 100643559
OBB: 114870929
SOC: 105196704
MPHA: 105835203
AEC: 105143165
ACEP: 105623125
PBAR: 105425708
VEM: 105563305
HST: 105190557
DQU: 106750778
CFO: 105255588
LHU: 105670881
PGC: 109851819
OBO: 105286972
PCF: 106785965
NVI: 100123596
CSOL: 105359496
MDL: 103576554
TCA: 660517
DPA: 109537933
ATD: 109601088
NVL: 108565321
API: 100163622
DNX: 107168497
RMD: 113559923
CLEC: 106663307
CEL: CELE_F33D4.2(itr-1)
CBR: CBG05938(Cbr-itr-1)
BMY: Bm1_37045
TSP: Tsp_10834
NVE: 5509439
HMG: 100202979
CRE: CHLREDRAFT_153750(RYR1)
 » show all
Reference
PMID:2554142
  Authors
Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N, Mikoshiba K
  Title
Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.
  Journal
Nature 342:32-8 (1989)
DOI:10.1038/342032a0
  Sequence
[mmu:16438]
LinkDB

KEGG   ORTHOLOGY: K04959
Entry
K04959                      KO                                     

Name
ITPR2
Definition
inositol 1,4,5-triphosphate receptor type 2
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04070  Phosphatidylinositol signaling system
ko04114  Oocyte meiosis
ko04210  Apoptosis
ko04218  Cellular senescence
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04750  Inflammatory mediator regulation of TRP channels
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04929  GnRH secretion
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05205  Proteoglycans in cancer
Disease
H02281  Isolated anhidrosis with normal sweat glands
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04020 Calcium signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04070 Phosphatidylinositol signaling system
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04022 cGMP-PKG signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04210 Apoptosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04218 Cellular senescence
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04621 NOD-like receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04625 C-type lectin receptor signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04929 GnRH secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04912 GnRH signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04915 Estrogen signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04921 Oxytocin signaling pathway
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04935 Growth hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04918 Thyroid hormone synthesis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04928 Parathyroid hormone synthesis, secretion and action
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04924 Renin secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04925 Aldosterone synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04927 Cortisol synthesis and secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09154 Digestive system
   04970 Salivary secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04971 Gastric acid secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04972 Pancreatic secretion
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09156 Nervous system
   04724 Glutamatergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04725 Cholinergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04728 Dopaminergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04726 Serotonergic synapse
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04720 Long-term potentiation
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04730 Long-term depression
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   04723 Retrograde endocannabinoid signaling
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05012 Parkinson disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05017 Spinocerebellar ataxia
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05020 Prion disease
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05022 Pathways of neurodegeneration - multiple diseases
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05163 Human cytomegalovirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3709(ITPR2)
PTR: 473389(ITPR2)
PPS: 100980378(ITPR2)
GGO: 101151502(ITPR2)
PON: 100434318(ITPR2)
NLE: 100599135(ITPR2)
MCC: 708714(ITPR2)
MCF: 102115744(ITPR2)
CSAB: 103218776(ITPR2)
RRO: 104675331(ITPR2)
RBB: 108523739(ITPR2)
SBQ: 101049881(ITPR2)
MMU: 16439(Itpr2)
MCAL: 110295833(Itpr2)
MPAH: 110317251(Itpr2)
RNO: 81678(Itpr2)
MUN: 110558908(Itpr2)
CGE: 100758965(Itpr2)
HGL: 101716022(Itpr2)
OCU: 100356806(ITPR2)
TUP: 102482868(ITPR2)
CFA: 486628(ITPR2)
VVP: 112917203(ITPR2)
AML: 100477888(ITPR2)
UMR: 103665275(ITPR2)
UAH: 113257782(ITPR2)
ORO: 101377380(ITPR2)
ELK: 111159979
FCA: 101101230(ITPR2)
PTG: 102971840(ITPR2)
PPAD: 109268756(ITPR2)
AJU: 106968786(ITPR2)
BTA: 281878(ITPR2)
BOM: 102269013(ITPR2)
BIU: 109558547(ITPR2)
BBUB: 102401062(ITPR2)
CHX: 102170858(ITPR2)
OAS: 101113317
SSC: 100517279(ITPR2)
CFR: 102517295(ITPR2)
CDK: 105102013(ITPR2)
BACU: 103018280(ITPR2)
LVE: 103078697(ITPR2)
OOR: 101281155(ITPR2)
DLE: 111176861(ITPR2)
PCAD: 102984842(ITPR2)
ECB: 100064557(ITPR2)
EPZ: 103546630(ITPR2) 103548182
EAI: 106834887(ITPR2)
MYB: 102256216(ITPR2)
MNA: 107525255(ITPR2)
HAI: 109372316
DRO: 112318382(ITPR2)
PALE: 102896356(ITPR2)
RAY: 107497427(ITPR2)
MJV: 108403293(ITPR2)
LAV: 100667845(ITPR2)
TMU: 101356404
MDO: 100010212(ITPR2)
SHR: 100921270(ITPR2)
PCW: 110193334(ITPR2)
OAA: 103164954(ITPR2)
GGA: 418212(ITPR2)
MGP: 100551445(ITPR2)
CJO: 107316928(ITPR2)
NMEL: 110396437(ITPR2)
APLA: 101791934(ITPR2)
ACYG: 106038242(ITPR2)
TGU: 100230706(ITPR2)
LSR: 110474888(ITPR2)
SCAN: 103819592(ITPR2)
GFR: 102036319(ITPR2)
FAB: 101811180(ITPR2)
PHI: 102112318(ITPR2)
PMAJ: 107204618(ITPR2)
CCAE: 111930014(ITPR2)
CCW: 104696157(ITPR2)
ETL: 114064981(ITPR2)
FPG: 101920370
FCH: 102052635(ITPR2)
CLV: 102096683(ITPR2)
EGZ: 104135140(ITPR2)
NNI: 104012694(ITPR2)
ACUN: 113489114(ITPR2)
PADL: 103924320(ITPR2)
AAM: 106488657
ASN: 102379727
AMJ: 102570264(ITPR2)
PSS: 102453428(ITPR2)
CMY: 102942754(ITPR2)
CPIC: 101931123(ITPR2)
ACS: 100567982(itpr2)
PVT: 110081241(ITPR2)
PBI: 103058322
PMUR: 107296465(ITPR2)
PMUA: 114604922(ITPR2)
GJA: 107125949(ITPR2)
XLA: 108710178
XTR: 100124748(itpr2)
NPR: 108786728(ITPR2)
DRE: 562585(itpr2)
SRX: 107730567(itpr2) 107740421
SGH: 107553933(itpr2) 107583890
IPU: 108264307(itpr2)
PHYP: 113534384(itpr2)
AMEX: 103025600
EEE: 113590571
TRU: 101063873(itpr2)
LCO: 104924371(itpr2)
NCC: 104954420
MZE: 101466928(itpr2)
ONL: 100690527(itpr2)
OLA: 101155191(itpr2)
XMA: 102220160(itpr2)
XCO: 114157038(itpr2)
PRET: 103466096(itpr2)
CVG: 107104059(itpr2)
NFU: 107388954(itpr2)
KMR: 108239960(itpr2)
ALIM: 106515612(itpr2)
AOCE: 111568340(itpr2)
CSEM: 103380150(itpr2)
POV: 109624047(itpr2)
LCF: 108875355(itpr2)
SDU: 111228375(itpr2)
SLAL: 111655344(itpr2)
HCQ: 109530334(itpr2)
BPEC: 110165611
MALB: 109970756(itpr2)
SASA: 100196824(itpr2)
ELS: 105022141(itpr2)
SFM: 108942564(itpr2)
PKI: 111845672(itpr2)
LCM: 102359880(ITPR2)
CMK: 103188869(itpr2)
RTP: 109918007(itpr2)
 » show all
Reference
  Authors
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
  Title
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
  Journal
J Biol Chem 280:10305-17 (2005)
DOI:10.1074/jbc.M413824200
  Sequence
[mmu:16439]
LinkDB

KEGG   ORTHOLOGY: K04960
Entry
K04960                      KO                                     

Name
ITPR3
Definition
inositol 1,4,5-triphosphate receptor type 3
Pathway
ko04020  Calcium signaling pathway
ko04022  cGMP-PKG signaling pathway
ko04070  Phosphatidylinositol signaling system
ko04114  Oocyte meiosis
ko04210  Apoptosis
ko04218  Cellular senescence
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04540  Gap junction
ko04611  Platelet activation
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04713  Circadian entrainment
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko04742  Taste transduction
ko04750  Inflammatory mediator regulation of TRP channels
ko04911  Insulin secretion
ko04912  GnRH signaling pathway
ko04915  Estrogen signaling pathway
ko04918  Thyroid hormone synthesis
ko04921  Oxytocin signaling pathway
ko04922  Glucagon signaling pathway
ko04924  Renin secretion
ko04925  Aldosterone synthesis and secretion
ko04927  Cortisol synthesis and secretion
ko04928  Parathyroid hormone synthesis, secretion and action
ko04929  GnRH secretion
ko04934  Cushing syndrome
ko04935  Growth hormone synthesis, secretion and action
ko04970  Salivary secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko05010  Alzheimer disease
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05017  Spinocerebellar ataxia
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05170  Human immunodeficiency virus 1 infection
ko05205  Proteoglycans in cancer
Disease
H00408  Type 1 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04020 Calcium signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04070 Phosphatidylinositol signaling system
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04022 cGMP-PKG signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04210 Apoptosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04218 Cellular senescence
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04621 NOD-like receptor signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04625 C-type lectin receptor signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09152 Endocrine system
   04911 Insulin secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04922 Glucagon signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04929 GnRH secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04912 GnRH signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04915 Estrogen signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04921 Oxytocin signaling pathway
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04935 Growth hormone synthesis, secretion and action
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04918 Thyroid hormone synthesis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04928 Parathyroid hormone synthesis, secretion and action
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04924 Renin secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04925 Aldosterone synthesis and secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04927 Cortisol synthesis and secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09154 Digestive system
   04970 Salivary secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04971 Gastric acid secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04972 Pancreatic secretion
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09156 Nervous system
   04724 Glutamatergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04725 Cholinergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04728 Dopaminergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04726 Serotonergic synapse
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04720 Long-term potentiation
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04730 Long-term depression
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04723 Retrograde endocannabinoid signaling
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09157 Sensory system
   04742 Taste transduction
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   04750 Inflammatory mediator regulation of TRP channels
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05012 Parkinson disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05014 Amyotrophic lateral sclerosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05017 Spinocerebellar ataxia
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05020 Prion disease
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05022 Pathways of neurodegeneration - multiple diseases
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05163 Human cytomegalovirus infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Ion channels [BR:ko04040]
 Ligand-gated channels
  IP3 receptor
   K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
Other DBs
GO: 0005220
TC: 1.A.3.2
Genes
HSA: 3710(ITPR3)
PTR: 462618(ITPR3)
PPS: 100982024(ITPR3)
GGO: 101124725(ITPR3)
PON: 100434127(ITPR3)
NLE: 100585914(ITPR3)
MCC: 718040(ITPR3)
MCF: 102116003(ITPR3)
CSAB: 103221654(ITPR3)
RRO: 104658948(ITPR3)
RBB: 108516255(ITPR3)
CJC: 100390843
SBQ: 101048916(ITPR3)
MMU: 16440(Itpr3)
MCAL: 110312193(Itpr3)
MPAH: 110338229(Itpr3)
RNO: 25679(Itpr3)
MUN: 110543748(Itpr3)
CGE: 100751775
NGI: 103739696(Itpr3)
HGL: 101706978(Itpr3)
CCAN: 109686691(Itpr3)
OCU: 100008939(ITPR3)
TUP: 102475587(ITPR3)
CFA: 481746(ITPR3)
VVP: 112913900(ITPR3)
AML: 100471747(ITPR3)
UMR: 103665553(ITPR3)
UAH: 113243814(ITPR3)
ORO: 101380808(ITPR3)
ELK: 111152507
FCA: 101087993(ITPR3)
PTG: 102967639(ITPR3)
PPAD: 109271454(ITPR3)
AJU: 106976077(ITPR3)
BTA: 281879(ITPR3)
BOM: 102271039(ITPR3)
BIU: 109576552(ITPR3)
BBUB: 102409793(ITPR3)
CHX: 102184768(ITPR3)
OAS: 114109674(ITPR3)
SSC: 100155015(ITPR3)
CFR: 102524078(ITPR3)
CDK: 105101373(ITPR3)
BACU: 102999302(ITPR3)
LVE: 103070387(ITPR3)
OOR: 101280894(ITPR3)
DLE: 111178692(ITPR3)
PCAD: 102992034(ITPR3)
ECB: 100053019(ITPR3)
EPZ: 103564724(ITPR3)
EAI: 106834634(ITPR3)
MYB: 102241889(ITPR3)
MYD: 102764661(ITPR3)
MNA: 107541588(ITPR3)
HAI: 109392407(ITPR3)
DRO: 112302101(ITPR3)
PALE: 102881783(ITPR3)
RAY: 107511965(ITPR3)
MJV: 108402938(ITPR3)
LAV: 100659666(ITPR3)
TMU: 101354392
MDO: 100025596(ITPR3)
SHR: 100916996(ITPR3)
PCW: 110217180(ITPR3)
OAA: 100088770(ITPR3)
GGA: 419910(ITPR3)
MGP: 104914537(ITPR3)
CJO: 107324903(ITPR3)
NMEL: 110388144(ITPR3)
APLA: 101792202(ITPR3)
ACYG: 106046157(ITPR3)
TGU: 100227554(ITPR3)
LSR: 110477170(ITPR3)
SCAN: 103823305(ITPR3)
GFR: 102036728(ITPR3)
FAB: 101809694(ITPR3)
PHI: 102109497(ITPR3)
PMAJ: 107214964(ITPR3)
CCAE: 111939798(ITPR3)
CCW: 104692535(ITPR3)
ETL: 114064083(ITPR3)
FPG: 101911646(ITPR3)
FCH: 102057380(ITPR3)
CLV: 102098742(ITPR3)
EGZ: 104125774(ITPR3)
NNI: 104013165(ITPR3)
ACUN: 113488982(ITPR3)
PADL: 103919873(ITPR3)
AAM: 106496749(ITPR3)
ASN: 102381395(ITPR3)
AMJ: 102567087(ITPR3)
PSS: 102449833(ITPR3)
CMY: 102939145(ITPR3)
CPIC: 101935702(ITPR3)
ACS: 100564450(itpr3)
PVT: 110080162(ITPR3)
PBI: 103048008(ITPR3)
PMUR: 107287061(ITPR3)
TSR: 106541215(ITPR3)
PMUA: 114599227(ITPR3)
GJA: 107117556(ITPR3)
XLA: 108709441
XTR: 100124749(itpr3)
NPR: 108787281(ITPR3)
DRE: 794666(itpr3)
SANH: 107668074(itpr3) 107695219
SGH: 107549213(itpr3) 107555587
CCAR: 109061957
IPU: 108265736(itpr3)
PHYP: 113526579(itpr3)
EEE: 113581076(itpr3)
TRU: 101074918
LCO: 104933529(itpr3)
MZE: 101481255(itpr3)
ONL: 100707448(itpr3)
OLA: 101170574(itpr3)
XMA: 102237995(itpr3)
XCO: 114141097(itpr3)
PRET: 103468120(itpr3)
CVG: 107097408(itpr3)
NFU: 107391515(itpr3)
KMR: 108251566(itpr3)
ALIM: 106527884
CSEM: 103384462(itpr3)
POV: 109642872
LCF: 108879748
SDU: 111235419(itpr3)
SLAL: 111673377(itpr3)
HCQ: 109526465(itpr3)
BPEC: 110158040(itpr3)
MALB: 109970976(itpr3)
SASA: 106572092
SALP: 111966445(itpr3) 111976834
ELS: 105027760(itpr3)
SFM: 108931222(itpr3)
PKI: 111844730(itpr3)
LCM: 102349825(ITPR3)
CMK: 103179112(itpr3)
SMIN: v1.2.035044.t1(symbB.v1.2.035044.t1)
EHX: EMIHUDRAFT_209909(IPR1)
 » show all
Reference
  Authors
Iwai M, Tateishi Y, Hattori M, Mizutani A, Nakamura T, Futatsugi A, Inoue T, Furuichi T, Michikawa T, Mikoshiba K
  Title
Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.
  Journal
J Biol Chem 280:10305-17 (2005)
DOI:10.1074/jbc.M413824200
  Sequence
[mmu:16440]
LinkDB

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