KEGG   ORTHOLOGY: K04982
Entry
K04982                      KO                                     

Name
TRPM7, CHAK1
Definition
transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
Pathway
ko04217  Necroptosis
ko04218  Cellular senescence
ko04621  NOD-like receptor signaling pathway
ko04978  Mineral absorption
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
   04218 Cellular senescence
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
  09154 Digestive system
   04978 Mineral absorption
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  Alpha family [OT]
   K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7
Other DBs
GO: 0005262
TC: 1.A.4.5.1
Genes
HSA: 54822(TRPM7)
PTR: 453429(TRPM7)
PPS: 100982703(TRPM7)
GGO: 101140728(TRPM7)
PON: 100437453(TRPM7)
NLE: 100587285(TRPM7)
MCC: 716755(TRPM7)
MCF: 102114767(TRPM7)
CSAB: 103245635(TRPM7)
RRO: 104656904(TRPM7)
RBB: 108544826(TRPM7)
CJC: 100401153(TRPM7)
SBQ: 101052786(TRPM7)
MMU: 58800(Trpm7)
MCAL: 110289320(Trpm7)
MPAH: 110317831(Trpm7)
RNO: 679906(Trpm7)
MUN: 110551943(Trpm7)
CGE: 100752689(Trpm7)
NGI: 103733047(Trpm7)
HGL: 101709993(Trpm7)
CCAN: 109699886(Trpm7)
OCU: 100350932(TRPM7)
TUP: 102492170(TRPM7) 106733924
CFA: 478300(TRPM7)
VVP: 112920061(TRPM7)
AML: 100482433(TRPM7)
UMR: 103676738(TRPM7)
UAH: 113269614(TRPM7)
ORO: 101381534(TRPM7)
ELK: 111158565
FCA: 101095177(TRPM7)
PPAD: 109262997(TRPM7)
AJU: 106967234(TRPM7)
BTA: 514642(TRPM7)
BOM: 102278251(TRPM7)
BIU: 109565130(TRPM7)
BBUB: 102396769(TRPM7)
CHX: 102173747(TRPM7)
OAS: 100037693(TRPM7)
SSC: 100169932(TRPM7)
CFR: 102518266(TRPM7)
CDK: 105102459(TRPM7)
BACU: 103015250(TRPM7)
LVE: 103082405(TRPM7)
OOR: 101284278(TRPM7)
DLE: 111181560(TRPM7)
PCAD: 102981704(TRPM7)
ECB: 102149157(TRPM7)
EPZ: 103546934(TRPM7)
EAI: 106838402(TRPM7)
MYB: 102256071(TRPM7)
MYD: 102755894(TRPM7)
MNA: 107534881(TRPM7)
HAI: 109394179(TRPM7)
DRO: 112311670(TRPM7)
PALE: 102884616(TRPM7)
RAY: 107501944(TRPM7)
MJV: 108391298(TRPM7)
LAV: 100672088(TRPM7)
TMU: 101349029
MDO: 100031256(TRPM7)
SHR: 100934039(TRPM7)
PCW: 110203550(TRPM7)
OAA: 100090926(TRPM7)
GGA: 427502(TRPM7)
MGP: 100542333(TRPM7)
CJO: 107318704(TRPM7)
NMEL: 110403612(TRPM7)
APLA: 101796059(TRPM7)
ACYG: 106043381
TGU: 100228325(TRPM7)
LSR: 110474258(TRPM7)
SCAN: 103816033(TRPM7)
FAB: 101813566(TRPM7)
PHI: 102106298(TRPM7)
PMAJ: 107209240(TRPM7)
CCAE: 111933879(TRPM7)
CCW: 104683979(TRPM7)
ETL: 114059935(TRPM7)
FCH: 114015105
CLV: 102086184(TRPM7)
EGZ: 104130794(TRPM7)
NNI: 104017260(TRPM7)
ACUN: 113483902(TRPM7)
PADL: 103922740(TRPM7)
AAM: 106496405
ASN: 102372173(TRPM7)
AMJ: 102566660(TRPM7)
PSS: 102461295
CMY: 102929346(TRPM7)
CPIC: 101940689(TRPM7)
ACS: 100559024(trpm7)
PVT: 110077231(TRPM7)
PBI: 103065308(TRPM7)
PMUR: 107293588(TRPM7)
TSR: 106546390(TRPM7)
PMUA: 114584753(TRPM7)
GJA: 107124454(TRPM7)
XLA: 100499162(trpm7.L) 108711406 108711407 108712895(trpm7.S)
XTR: 100329113(trpm7) 100497855
NPR: 108804799 108804815(TRPM7)
DRE: 280653(trpm7)
SRX: 107715248 107724022(trpm7)
SGH: 107569970(trpm7) 107595391
CCAR: 109044934(trpm7)
IPU: 108264473(trpm7)
PHYP: 113526647
AMEX: 111197571(trpm7)
EEE: 113585346(trpm7)
TRU: 101077272(trpm7)
LCO: 104929767(trpm7)
NCC: 104946310
MZE: 101479476(trpm7)
ONL: 109194405(trpm7)
OLA: 101156483(trpm7)
XMA: 102224766(trpm7)
XCO: 114143366(trpm7)
PRET: 103462173(trpm7)
CVG: 107099438(trpm7)
NFU: 107373599(trpm7)
KMR: 108237368(trpm7)
ALIM: 106518980(trpm7)
AOCE: 111568465(trpm7)
CSEM: 103379369(trpm7)
POV: 109624842(trpm7)
LCF: 108876909(trpm7)
SDU: 111218170(trpm7)
SLAL: 111659123(trpm7)
HCQ: 109513898(trpm7)
BPEC: 110175509(trpm7)
MALB: 109955892 109971580(trpm7)
OTW: 112249377(trpm7)
SALP: 112076906
ELS: 105022650(trpm7) 106024192
SFM: 108941140(trpm7) 108942028
PKI: 111845024(trpm7) 111846675
LCM: 102357315(TRPM7)
CMK: 103186533(trpm7)
SHX: MS3_06156
 » show all
Reference
  Authors
Schmitz C, Perraud AL, Johnson CO, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM
  Title
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.
  Journal
Cell 114:191-200 (2003)
DOI:10.1016/S0092-8674(03)00556-7
Reference
  Authors
Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A
  Title
LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.
  Journal
Nature 411:590-5 (2001)
DOI:10.1038/35079092
  Sequence
[hsa:54822]
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