KEGG   ORTHOLOGY: K05063
Entry
K05063                      KO                                     

Name
IL12RB1, CD212
Definition
interleukin 12 receptor beta-1
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04659 Th17 cell differentiation
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
   04090 CD molecules
    K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
CD molecules [BR:ko04090]
 Proteins
  K05063  CD212, IL12RB1; interleukin 12 receptor, beta 1
Genes
HSA: 3594(IL12RB1)
PTR: 455851(IL12RB1)
PPS: 100979712(IL12RB1)
GGO: 101134933(IL12RB1)
PON: 100435478(IL12RB1)
NLE: 100605040(IL12RB1)
MCC: 574199(IL12RB1)
MCF: 102143359(IL12RB1)
CSAB: 103234165(IL12RB1)
RRO: 104680608(IL12RB1)
RBB: 108534277(IL12RB1)
CJC: 100399291(IL12RB1)
SBQ: 101032718(IL12RB1)
MMU: 16161(Il12rb1)
MCAL: 110300406(Il12rb1)
MPAH: 110336813(Il12rb1)
RNO: 171333(Il12rb1)
MUN: 110549207(Il12rb1)
CGE: 100763378(Il12rb1)
NGI: 103726945(Il12rb1)
HGL: 101702338(Il12rb1)
CCAN: 109699530(Il12rb1)
TUP: 102470262(IL12RB1)
CFA: 484828(IL12RB1)
VVP: 112913171(IL12RB1)
AML: 100474774(IL12RB1)
UMR: 103674947(IL12RB1)
UAH: 113256701(IL12RB1)
ORO: 101372587(IL12RB1)
ELK: 111144102
FCA: 101093085(IL12RB1)
PTG: 102959877(IL12RB1)
PPAD: 109247602(IL12RB1)
AJU: 106969152(IL12RB1)
BTA: 524299(IL12RB1)
BOM: 102286576(IL12RB1)
BIU: 109561420(IL12RB1)
BBUB: 102403765(IL12RB1)
CHX: 102172253(IL12RB1)
OAS: 101110054(IL12RB1)
SSC: 100271900(IL12RB1)
CFR: 102512953(IL12RB1)
CDK: 105101865(IL12RB1)
BACU: 103009591(IL12RB1)
LVE: 103081698(IL12RB1)
OOR: 101281920(IL12RB1)
DLE: 111166653(IL12RB1)
PCAD: 102991223(IL12RB1)
ECB: 100146965(IL12RB1)
EPZ: 103561544(IL12RB1)
EAI: 106825010(IL12RB1)
MYB: 102253710(IL12RB1)
MYD: 102769690(IL12RB1)
MNA: 107535370(IL12RB1)
HAI: 109382356(IL12RB1)
DRO: 112305028(IL12RB1)
PALE: 102878946(IL12RB1)
RAY: 107521689(IL12RB1)
MJV: 108383562(IL12RB1)
LAV: 100672726(IL12RB1)
TMU: 101351266
MDO: 103105099(IL12RB1)
SHR: 105749415(IL12RB1)
PCW: 110223476(IL12RB1)
OAA: 100079998(IL12RB1)
GGA: 101749221(IL12RB1)
MGP: 104915407
CJO: 107325690(IL12RB1)
NMEL: 110388754(IL12RB1)
APLA: 101797086(IL12RB1)
ACYG: 106044936(IL12RB1)
TGU: 115490890(IL12RB1)
SCAN: 103822011(IL12RB1)
GFR: 102037576(IL12RB1)
FAB: 101812402(IL12RB1)
PHI: 102100998(IL12RB1)
PMAJ: 107215365(IL12RB1)
CCAE: 111940322(IL12RB1)
CCW: 104697031(IL12RB1)
ETL: 114069506(IL12RB1)
FPG: 101911543(IL12RB1)
FCH: 102051332(IL12RB1)
CLV: 102098000(IL12RB1)
EGZ: 104135651(IL12RB1)
NNI: 104018782(IL12RB1)
ACUN: 113489367(IL12RB1)
ASN: 102378143(IL12RB1)
AMJ: 106737527(IL12RB1)
PSS: 102461655(IL12RB1)
CPIC: 101941042(IL12RB1)
ACS: 103282283(il12rb1)
PVT: 110072563(IL12RB1)
PBI: 112540224(IL12RB1)
PMUR: 114922203(IL12RB1)
TSR: 106543464(IL12RB1)
PMUA: 114588688(IL12RB1)
XLA: 108720006
XTR: 100496683(il12rb1)
DRE: 101883301(si:dkey-13m1.2)
IPU: 108270768
PHYP: 113528465
AMEX: 103028625
TRU: 105417954
LCO: 104920404
NCC: 104959360(il12rb1)
MZE: 101472333
ONL: 102077946
OLA: 105353921
XMA: 111609789(il12rb1)
XCO: 114151489(il12rb1)
PRET: 103463422
CVG: 107099666(il12rb1)
KMR: 108234318(il12rb1)
ALIM: 106519187
AOCE: 111576546
CSEM: 103395987
LCF: 108881184(il12rb1)
SDU: 111216416(il12rb1)
SLAL: 111669988(il12rb1)
HCQ: 109519017
BPEC: 110167972
MALB: 109966833
ELS: 105026196
SFM: 108930531(il12rb1)
 » show all
Reference
PMID:8617302
  Authors
Wu CY, Warrier RR, Carvajal DM, Chua AO, Minetti LJ, Chizzonite R, Mongini PK, Stern AS, Gubler U, Presky DH, Gately MK
  Title
Biological function and distribution of human interleukin-12 receptor beta chain.
  Journal
Eur J Immunol 26:345-50 (1996)
DOI:10.1002/eji.1830260212
  Sequence
[hsa:3594]
Reference
PMID:7911493
  Authors
Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK, et al.
  Title
Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.
  Journal
J Immunol 153:128-36 (1994)
  Sequence
[hsa:3594]
LinkDB

KEGG   ORTHOLOGY: K05064
Entry
K05064                      KO                                     

Name
IL12RB2
Definition
interleukin 12 receptor beta-2
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease
Disease
H01476  Behcet disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05064  IL12RB2; interleukin 12 receptor beta-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05064  IL12RB2; interleukin 12 receptor beta-2
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05064  IL12RB2; interleukin 12 receptor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05064  IL12RB2; interleukin 12 receptor beta-2
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05064  IL12RB2; interleukin 12 receptor beta-2
Genes
HSA: 3595(IL12RB2)
PTR: 469348(IL12RB2)
PPS: 100984257(IL12RB2)
GGO: 101144503(IL12RB2)
PON: 100456779(IL12RB2)
NLE: 100582797(IL12RB2)
MCC: 700677(IL12RB2)
MCF: 102131165(IL12RB2)
CSAB: 103224656(IL12RB2)
RRO: 104657309(IL12RB2)
RBB: 108532946(IL12RB2)
CJC: 100393796(IL12RB2)
SBQ: 101048468(IL12RB2)
MMU: 16162(Il12rb2)
MCAL: 110296634(Il12rb2)
MPAH: 110316620(Il12rb2)
RNO: 171334(Il12rb2)
CGE: 100758602(Il12rb2)
NGI: 103743352(Il12rb2)
HGL: 101717608(Il12rb2)
CCAN: 109698313(Il12rb2)
OCU: 100350416(IL12RB2)
TUP: 102494666(IL12RB2)
CFA: 489550(IL12RB2)
VVP: 112907882(IL12RB2)
AML: 100478166(IL12RB2)
UMR: 103663034(IL12RB2)
UAH: 113254551(IL12RB2)
ORO: 101376489(IL12RB2)
ELK: 111143098
FCA: 101088012(IL12RB2)
PTG: 102953239(IL12RB2)
PPAD: 109266706(IL12RB2)
AJU: 106985194(IL12RB2)
BTA: 282452(IL12RB2)
BOM: 102265420(IL12RB2)
BIU: 109556179(IL12RB2)
BBUB: 102403761(IL12RB2)
CHX: 102176287(IL12RB2)
OAS: 100820736(IL12RB2)
SSC: 397178(IL12RB2)
CFR: 102523963(IL12RB2)
CDK: 105096624(IL12RB2)
BACU: 103019963(IL12RB2)
LVE: 103079416(IL12RB2)
OOR: 101283273(IL12RB2)
DLE: 111178439(IL12RB2)
PCAD: 102991572
ECB: 100053757(IL12RB2)
EPZ: 103561906(IL12RB2)
EAI: 106825064(IL12RB2)
MYB: 102240232(IL12RB2)
MYD: 102751523(IL12RB2)
MNA: 107533449(IL12RB2)
HAI: 109384960(IL12RB2)
DRO: 112309047(IL12RB2)
PALE: 102885605(IL12RB2)
RAY: 107520563(IL12RB2)
MJV: 108404889(IL12RB2)
LAV: 100666176(IL12RB2)
TMU: 101352491
MDO: 103105069(IL12RB2)
SHR: 100931154(IL12RB2)
PCW: 110212954(IL12RB2)
OAA: 100081756(IL12RB2)
GGA: 424705(IL12RB2)
MGP: 100540289
CJO: 107317747(IL12RB2)
NMEL: 110402621(IL12RB2)
APLA: 101791874(IL12RB2)
ACYG: 106043599(IL12RB2)
TGU: 115496184
LSR: 110473252
SCAN: 103815228
GFR: 102044094(IL12RB2)
FAB: 101814678(IL12RB2)
PHI: 102101267(IL12RB2)
PMAJ: 107207898(IL12RB2)
CCW: 104695495(IL12RB2)
ETL: 114061068(IL12RB2)
FPG: 101921709(IL12RB2)
FCH: 102052886(IL12RB2)
CLV: 102091062(IL12RB2)
EGZ: 104123868(IL12RB2)
NNI: 104009324
ACUN: 113483179(IL12RB2)
PADL: 103914046(IL12RB2)
AAM: 106486526(IL12RB2)
ASN: 102373922(IL12RB2)
AMJ: 102576733(IL12RB2)
PSS: 102452148(IL12RB2)
CMY: 102947382(IL12RB2)
CPIC: 101932982(IL12RB2)
ACS: 103280214(il12rb2) 103281926
PVT: 110079852(IL12RB2)
PBI: 103053316(IL12RB2)
PMUR: 114923702(IL12RB2)
TSR: 106548941(IL12RB2)
PMUA: 114598875(IL12RB2)
GJA: 107114339(IL12RB2)
DRE: 100134971(il12rb2)
CCAR: 109093447
IPU: 108271892
PHYP: 113538213
AMEX: 103034527
EEE: 113570424
ALIM: 106532034
SASA: 100306791(i12r2) 106613945
OTW: 112251058
LCM: 102353471 102361820(IL27RA)
CMK: 103189128(il12rb2)
RTP: 109926856 109926857(il12rb2)
 » show all
Reference
PMID:8943050
  Authors
Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U
  Title
A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits.
  Journal
Proc Natl Acad Sci U S A 93:14002-7 (1996)
DOI:10.1073/pnas.93.24.14002
  Sequence
[hsa:3595]
LinkDB

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